Panos G Georgopoulos

Summary

Affiliation: Rutgers University
Country: USA

Publications

  1. pmc Computational multiscale toxicodynamic modeling of silver and carbon nanoparticle effects on mouse lung function
    Dwaipayan Mukherjee
    Department of Environmental and Occupational Medicine, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, United States of America Department of Chemical and Biochemical Engineering, Rutgers University, Piscataway, New Jersey, United States of America
    PLoS ONE 8:e80917. 2013
  2. pmc A unified multiscale field/network/agent based modeling framework for human and ecological health risk analysis
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, Piscataway, NJ 08854, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6420-3. 2009
  3. ncbi request reprint Hospital response to chemical terrorism: personal protective equipment, training, and operations planning
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute EOHSI, UMDNJ RW Johnson Medical School and Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Am J Ind Med 46:432-45. 2004
  4. pmc Reconstructing population exposures to environmental chemicals from biomarkers: challenges and opportunities
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute EOHSI, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, Piscataway, NJ 08854, USA
    J Expo Sci Environ Epidemiol 19:149-71. 2009
  5. ncbi request reprint Assessment of human exposure to copper: a case study using the NHEXAS database
    Panos G Georgopoulos
    Exposure Measurement and Assessment Division, Environmental and Occupational Health Sciences Institute EOHSI a Joint Institute of UMDNJ Robert Wood Johnson Medical School and Rutgers University, Piscataway, NJ 08854, USA
    J Expo Sci Environ Epidemiol 16:397-409. 2006
  6. pmc Biologically based modeling of multimedia, multipathway, multiroute population exposures to arsenic
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute EOHSI, A Joint Institute of UMDNJ R W Johnson Medical School and Rutgers University, 170 Frelinghuysen Road, Piscataway, New Jersey 08854, USA
    J Expo Sci Environ Epidemiol 18:462-76. 2008
  7. ncbi request reprint From a theoretical framework of human exposure and dose assessment to computational system implementation: the Modeling ENvironment for TOtal Risk Studies (MENTOR)
    Panos G Georgopoulos
    Exposure Measurement and Assessment Science Division, Environmental and Occupational Health Sciences Institute, UMDNJ Robert Wood Johnson Medical School and Rutgers University, Piscataway, New Jersey 08854, USA
    J Toxicol Environ Health B Crit Rev 9:457-83. 2006
  8. pmc Modeling of personal exposures to ambient air toxics in Camden, New Jersey: an evaluation study
    Sheng Wei Wang
    Exposure Science Division, Environmental and Occupational Health Sciences Institute, a Joint Institute of the University of Medicine and Dentistry of New Jersey R W Johnson Medical School and Rutgers University, Piscataway, NJ, USA
    J Air Waste Manag Assoc 59:733-46. 2009
  9. ncbi request reprint A source-to-dose assessment of population exposures to fine PM and ozone in Philadelphia, PA, during a summer 1999 episode
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute, Piscataway, New Jersey, USA
    J Expo Anal Environ Epidemiol 15:439-57. 2005
  10. pmc Exposure indices for the National Children's Study: application to inhalation exposures in Queens County, NY
    Sastry S Isukapalli
    Environmental and Occupational Health Science Institute, EOHSI, 170 Frelinghuysen Road, Piscataway, New Jersey 08854, USA
    J Expo Sci Environ Epidemiol 23:22-31. 2013

Collaborators

Detail Information

Publications23

  1. pmc Computational multiscale toxicodynamic modeling of silver and carbon nanoparticle effects on mouse lung function
    Dwaipayan Mukherjee
    Department of Environmental and Occupational Medicine, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, United States of America Department of Chemical and Biochemical Engineering, Rutgers University, Piscataway, New Jersey, United States of America
    PLoS ONE 8:e80917. 2013
    ..The predictions were found to follow the trends of observed changes in mouse surfactant composition over 7 days post dosing, and are in good agreement with the observed changes in mouse lung function over the same period of time. ..
  2. pmc A unified multiscale field/network/agent based modeling framework for human and ecological health risk analysis
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, Piscataway, NJ 08854, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6420-3. 2009
    ..These examples include problems describing human health risk assessment, ecological risk assessment, and environmentally caused disease...
  3. ncbi request reprint Hospital response to chemical terrorism: personal protective equipment, training, and operations planning
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute EOHSI, UMDNJ RW Johnson Medical School and Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Am J Ind Med 46:432-45. 2004
    ..The ERP must address OSHA, EPA, and JCAHO requirements...
  4. pmc Reconstructing population exposures to environmental chemicals from biomarkers: challenges and opportunities
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute EOHSI, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, Piscataway, NJ 08854, USA
    J Expo Sci Environ Epidemiol 19:149-71. 2009
    ....
  5. ncbi request reprint Assessment of human exposure to copper: a case study using the NHEXAS database
    Panos G Georgopoulos
    Exposure Measurement and Assessment Division, Environmental and Occupational Health Sciences Institute EOHSI a Joint Institute of UMDNJ Robert Wood Johnson Medical School and Rutgers University, Piscataway, NJ 08854, USA
    J Expo Sci Environ Epidemiol 16:397-409. 2006
    ..The values were well below the upper tolerable intake value of 10,000 microg/day. The inhalation route consistently acted as only a minor contributor to the total exposure...
  6. pmc Biologically based modeling of multimedia, multipathway, multiroute population exposures to arsenic
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute EOHSI, A Joint Institute of UMDNJ R W Johnson Medical School and Rutgers University, 170 Frelinghuysen Road, Piscataway, New Jersey 08854, USA
    J Expo Sci Environ Epidemiol 18:462-76. 2008
    ....
  7. ncbi request reprint From a theoretical framework of human exposure and dose assessment to computational system implementation: the Modeling ENvironment for TOtal Risk Studies (MENTOR)
    Panos G Georgopoulos
    Exposure Measurement and Assessment Science Division, Environmental and Occupational Health Sciences Institute, UMDNJ Robert Wood Johnson Medical School and Rutgers University, Piscataway, New Jersey 08854, USA
    J Toxicol Environ Health B Crit Rev 9:457-83. 2006
    ....
  8. pmc Modeling of personal exposures to ambient air toxics in Camden, New Jersey: an evaluation study
    Sheng Wei Wang
    Exposure Science Division, Environmental and Occupational Health Sciences Institute, a Joint Institute of the University of Medicine and Dentistry of New Jersey R W Johnson Medical School and Rutgers University, Piscataway, NJ, USA
    J Air Waste Manag Assoc 59:733-46. 2009
    ..Non-ambient sources were also found as significant contributors to personal exposures to benzene and toluene for the population studied...
  9. ncbi request reprint A source-to-dose assessment of population exposures to fine PM and ozone in Philadelphia, PA, during a summer 1999 episode
    Panos G Georgopoulos
    Environmental and Occupational Health Sciences Institute, Piscataway, New Jersey, USA
    J Expo Anal Environ Epidemiol 15:439-57. 2005
    ..Future work will focus on incorporating the effects of commuting patterns on population exposure/dose assessments as well as on extending the MENTOR/SHEDS applications to seasonal/annual studies and to other areas in the U.S...
  10. pmc Exposure indices for the National Children's Study: application to inhalation exposures in Queens County, NY
    Sastry S Isukapalli
    Environmental and Occupational Health Science Institute, EOHSI, 170 Frelinghuysen Road, Piscataway, New Jersey 08854, USA
    J Expo Sci Environ Epidemiol 23:22-31. 2013
    ..The results also serve as an example application of the EI for use in other exposure and outcome studies...
  11. ncbi request reprint An evaluation of the role of risk-based decision-making in a former manufactured gas plant site remediation
    Vikram M Vyas
    Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School and Rutgers, State University of New Jersey, Piscataway, NJ 08854 1179, USA
    J Air Waste Manag Assoc 56:225-35. 2006
    ..The lessons from this case study are generalizable to more complicated remediation cases, when supported by correspondingly sophisticated technical approaches...
  12. ncbi request reprint A Tiered Framework for Risk-Relevant Characterization and Ranking of Chemical Exposures: Applications to the National Children's Study (NCS)
    Panos G Georgopoulos
    Rutgers University, Environmental and Occupational Health Science Institute EOHSI, Piscataway, NJ, USA
    Risk Anal 34:1299-316. 2014
    ..Applications of TiER demonstrate the feasibility of developing risk-relevant exposure characterizations for pollutants using extant environmental and demographic/socioeconomic data. ..
  13. pmc A semi-mechanistic integrated toxicokinetic-toxicodynamic (TK/TD) model for arsenic(III) in hepatocytes
    Spyros K Stamatelos
    Environmental and Occupational Health Sciences Institute EOHSI a Joint Institute of UMDNJ Robert Wood Johnson Medical School and Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    J Theor Biol 317:244-56. 2013
    ....
  14. pmc A Bayesian population PBPK model for multiroute chloroform exposure
    Yuching Yang
    Exposure Science Division, Environmental and Occupational Health Sciences Institute, Joint Institute of UMDNJ Robert Wood Johnson Medical School and Rutgers University, Piscataway, NJ 08854, USA
    J Expo Sci Environ Epidemiol 20:326-41. 2010
    ..This study demonstrates the use of the Bayesian approach to optimize PBPK model parameters for typical household exposure scenarios...
  15. pmc Using national and local extant data to characterize environmental exposures in the national children's study: Queens County, New York
    Paul J Lioy
    Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry, New Jersey Robert Wood Johnson Medical School and Rutgers University, Piscataway, New Jersey, USA
    Environ Health Perspect 117:1494-504. 2009
    ..To fill major data gaps, extant data will be required for each study location. The Queens Vanguard Center has examined the extent of those needs and the types of data that are generally and possibly locally available...
  16. pmc Mathematical model of uptake and metabolism of arsenic(III) in human hepatocytes - Incorporation of cellular antioxidant response and threshold-dependent behavior
    Spyros K Stamatelos
    Environmental and Occupational Health Sciences Institute EOHSI, a joint institute of UMDNJ Robert Wood Johnson Medical School and Rutgers University, 170 Frelinghuysen Rd, Piscataway, NJ 08854, USA
    BMC Syst Biol 5:16. 2011
    ..Notable features of this model are the incorporation of arsenic-glutathione complex formation and a "switch-like" formulation to describe the antioxidant response of hepatocytes to arsenic exposure...
  17. pmc New Jersey: a case study of the reduction in urban and suburban air pollution from the 1950s to 2010
    Paul J Lioy
    Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School and Rutgers University, Piscataway, New Jersey, USA
    Environ Health Perspect 119:1351-5. 2011
    ....
  18. ncbi request reprint Development and application of a methodology for determining background groundwater quality at the Savannah River Site
    Vikram M Vyas
    Exposure Assessment and Measurement Division, Environmental and Occupational Health Sciences Institute, Rutgers, The State University of New Jersey and University of Medicine and Dentistry of New Jersey, Piscataway, NJ, USA
    J Air Waste Manag Assoc 56:159-68. 2006
    ..S. Department of Energy Savannah River Site facility, and results for four representative constituents (aluminum, arsenic, mercury, and tritium) are discussed...
  19. pmc Bayesian Analysis of a Lipid-Based Physiologically Based Toxicokinetic Model for a Mixture of PCBs in Rats
    Alan F Sasso
    Environmental and Occupational Health Sciences Institute, UMDNJ RW Johnson Medical School, Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    J Toxicol 2012:895391. 2012
    ..The linked PBTK/induction model remained on a lipid basis and was capable of modeling PCB concentrations in multiple tissues for all dose levels and dose profiles...
  20. pmc A generalized physiologically-based toxicokinetic modeling system for chemical mixtures containing metals
    Alan F Sasso
    Environmental and Occupational Health Sciences Institute, a joint institute of UMDNJ Robert Wood Johnson Medical School and Rutgers University, Piscataway, New Jersey, USA
    Theor Biol Med Model 7:17. 2010
    ..There is a need, therefore, for a consistent modeling framework that would allow the systematic study of cumulative risks from complex mixtures of contaminants...
  21. pmc Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time response and inhibitor effect
    Donald R Gerecke
    Environmental and Occupational Health Sciences Institute EOHSI, a joint institute of UMDNJ RW Johnson Medical School and Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Toxicol Appl Pharmacol 234:156-65. 2009
    ..These results can help in understanding the molecular mechanism of SM-induced blistering, as well as to test the efficacy of different inhibitors...
  22. pmc Climate change effect on Betula (birch) and Quercus (oak) pollen seasons in the United States
    Yong Zhang
    Environmental and Occupational Health Sciences Institute EOHSI A Joint Institute of UMDNJ RW Johnson Medical School and Rutgers University, Piscataway, NJ, 08854, USA
    Int J Biometeorol 58:909-19. 2014
    ..Simulation results indicated that responses of birch and oak pollen seasons to climate change are expected to vary for different regions...
  23. ncbi request reprint Concepts in developing health-based indicators for ozone
    Clifford P Weisel
    Environmental and Occupational Health Sciences Institute, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Int Arch Occup Environ Health 75:415-22. 2002
    ..g., changes in the prevalence of adverse health outcomes attributed to the pollutant. This manuscript presents the concepts of using asthma emergency room (ER) visits and hospital admission as potential health-based indicators for ozone...