Gyorgy Buzsaki

Summary

Affiliation: Rutgers University
Country: USA

Publications

  1. ncbi request reprint Temporal encoding of place sequences by hippocampal cell assemblies
    George Dragoi
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    Neuron 50:145-57. 2006
  2. pmc Neural syntax: cell assemblies, synapsembles, and readers
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Neuron 68:362-85. 2010
  3. pmc Pattern and inhibition-dependent invasion of pyramidal cell dendrites by fast spikes in the hippocampus in vivo
    G Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark 07102, USA
    Proc Natl Acad Sci U S A 93:9921-5. 1996
  4. ncbi request reprint Neuroscience. Similar is different in hippocampal networks
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Science 309:568-9. 2005
  5. ncbi request reprint Neuronal oscillations in cortical networks
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, State University of New Jersey, Newark, NJ 07102, USA
    Science 304:1926-9. 2004
  6. ncbi request reprint Large-scale recording of neuronal ensembles
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, New Jersey 07102, USA
    Nat Neurosci 7:446-51. 2004
  7. pmc Inhibition and brain work
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
    Neuron 56:771-83. 2007
  8. ncbi request reprint Hippocampal network patterns of activity in the mouse
    G Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Neuroscience 116:201-11. 2003
  9. ncbi request reprint Homeostatic maintenance of neuronal excitability by burst discharges in vivo
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Cereb Cortex 12:893-9. 2002
  10. ncbi request reprint Hippocampal GABAergic interneurons: a physiological perspective
    G Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Neurochem Res 26:899-905. 2001

Research Grants

  1. Imaging Local Network Activity in Vivo
    Gyorgy Buzsaki; Fiscal Year: 2006
  2. NETWORK COOPERATION IN THE HIPPOCAMPUS IN VIVO
    Gyorgy Buzsaki; Fiscal Year: 2007
  3. Hippocampal interneuronal network (MH 54671)
    Gyorgy Buzsaki; Fiscal Year: 2007
  4. NETWORK COOPERATION IN THE HIPPOCAMPUS IN VIVO
    Gyorgy Buzsaki; Fiscal Year: 2009
  5. NETWORK COOPERATION IN THE HIPPOCAMPUS IN VIVO
    Gyorgy Buzsaki; Fiscal Year: 2010
  6. Hippocampal interneuronal network (MH 54671)
    Gyorgy Buzsaki; Fiscal Year: 2010
  7. NETWORK COOPERATION IN THE HIPPOCAMPUS IN VIVO
    Gyorgy Buzsaki; Fiscal Year: 2003
  8. HIPPOCAMPAL INTERNEURONAL NETWORK
    Gyorgy Buzsaki; Fiscal Year: 1999
  9. CRCNS: Dynamics of the auditory cortical column
    Gyorgy Buzsaki; Fiscal Year: 2010

Collaborators

Detail Information

Publications65

  1. ncbi request reprint Temporal encoding of place sequences by hippocampal cell assemblies
    George Dragoi
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    Neuron 50:145-57. 2006
    ..These observations suggest that interleaving CA3 neuronal sequences bind CA1 assemblies representing overlapping past, present, and future locations into single episodes...
  2. pmc Neural syntax: cell assemblies, synapsembles, and readers
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Neuron 68:362-85. 2010
    ..The existing support for this tripartite framework is reviewed and strategies for experimental testing of its predictions are discussed...
  3. pmc Pattern and inhibition-dependent invasion of pyramidal cell dendrites by fast spikes in the hippocampus in vivo
    G Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark 07102, USA
    Proc Natl Acad Sci U S A 93:9921-5. 1996
    ....
  4. ncbi request reprint Neuroscience. Similar is different in hippocampal networks
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Science 309:568-9. 2005
  5. ncbi request reprint Neuronal oscillations in cortical networks
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, State University of New Jersey, Newark, NJ 07102, USA
    Science 304:1926-9. 2004
    ....
  6. ncbi request reprint Large-scale recording of neuronal ensembles
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, New Jersey 07102, USA
    Nat Neurosci 7:446-51. 2004
    ....
  7. pmc Inhibition and brain work
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
    Neuron 56:771-83. 2007
    ..Herein we examine issues relevant to an assessment of the work performed by inhibitory interneurons in the service of brain function...
  8. ncbi request reprint Hippocampal network patterns of activity in the mouse
    G Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Neuroscience 116:201-11. 2003
    ..We suggest that the main hippocampal network patterns are mediated by similar pathways and mechanisms in mouse and rat...
  9. ncbi request reprint Homeostatic maintenance of neuronal excitability by burst discharges in vivo
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Cereb Cortex 12:893-9. 2002
    ....
  10. ncbi request reprint Hippocampal GABAergic interneurons: a physiological perspective
    G Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Neurochem Res 26:899-905. 2001
    ..Experiments on hippocampal interneurons are reviewed and possible solutions for some of these complex functions are illustrated...
  11. ncbi request reprint Intracellular features predicted by extracellular recordings in the hippocampus in vivo
    D A Henze
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    J Neurophysiol 84:390-400. 2000
    ..This theoretical maximum is in contrast to the approximately six units that are usually detected per tetrode. From this, we conclude that a large percentage of hippocampal CA1 pyramidal cells are silent in any given behavioral condition...
  12. ncbi request reprint Theta oscillations in the hippocampus
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey and Neurological Institute of New Jersey, Newark, NJ 07102, USA
    Neuron 33:325-40. 2002
    ..Nevertheless, numerous critical issues regarding both the generation of theta oscillations and their functional significance remain challenges for future research...
  13. ncbi request reprint Memory consolidation during sleep: a neurophysiological perspective
    G Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    J Sleep Res 7:17-23. 1998
    ..These observations suggest that sleep patterns in the limbic system are essential for the preservation of experience-induced synaptic modifications...
  14. ncbi request reprint Hippocampal pyramidal cell-interneuron spike transmission is frequency dependent and responsible for place modulation of interneuron discharge
    Lisa Marshall
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    J Neurosci 22:RC197. 2002
    ..Thus, single pyramidal neurons can effectively determine the firing patterns of their interneuron targets...
  15. pmc Theta and gamma coordination of hippocampal networks during waking and rapid eye movement sleep
    Sean M Montgomery
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, New Jersey 07102, USA
    J Neurosci 28:6731-41. 2008
    ..We hypothesize that tonic REM sleep may support off-line mnemonic processing, whereas phasic bursts of activity during REM may promote memory consolidation...
  16. ncbi request reprint Integration and segregation of activity in entorhinal-hippocampal subregions by neocortical slow oscillations
    Yoshikazu Isomura
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, New Jersey 07102, USA
    Neuron 52:871-82. 2006
    ..Thus, neo/paleocortical and hippocampal networks periodically reset, self-organize, and temporally coordinate their cell assemblies via the slow oscillation...
  17. pmc Internally generated cell assembly sequences in the rat hippocampus
    Eva Pastalkova
    Center for Molecular and Behavioral Neuroscience, Rutgers, State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Science 321:1322-7. 2008
    ..Such sequences were not formed in control (nonmemory) tasks. We hypothesize that neuronal representations, evolved for encoding distance in spatial navigation, also support episodic recall and the planning of action sequences...
  18. pmc Theta oscillations provide temporal windows for local circuit computation in the entorhinal-hippocampal loop
    Kenji Mizuseki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
    Neuron 64:267-80. 2009
    ..We hypothesize that the temporal windows set by the theta cycles allow for local circuit interactions and thus a considerable degree of computational independence in subdivisions of the EC-hippocampal loop...
  19. ncbi request reprint Single granule cells reliably discharge targets in the hippocampal CA3 network in vivo
    Darrell A Henze
    Center for Molecular and Behavioral Neuroscience, Rutgers University, The State University of New Jersey, 197 University Avenue, Newark, New Jersey 07102, USA
    Nat Neurosci 5:790-5. 2002
    ..In addition, we suggest that information in single granule cells is converted into a temporal delay code in target CA3 pyramidal cells and interneurons. These data demonstrate how a neural circuit of the CNS may process information...
  20. ncbi request reprint Place representation within hippocampal networks is modified by long-term potentiation
    George Dragoi
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
    Neuron 39:843-53. 2003
    ..The findings support the view that learned place representation can be accomplished by LTP-like synaptic plasticity within intrahippocampal networks...
  21. ncbi request reprint Mechanisms of gamma oscillations in the hippocampus of the behaving rat
    Jozsef Csicsvari
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Neuron 37:311-22. 2003
    ..CA3 pyramidal neurons discharged CA3 and CA1 interneurons at latencies indicative of monosynaptic connections. Intrahippocampal gamma oscillation emerges in the CA3 recurrent system, which entrains the CA1 region via its interneurons...
  22. pmc Entrainment of neocortical neurons and gamma oscillations by the hippocampal theta rhythm
    Anton Sirota
    Center for Molecular and Behavioral Neuroscience, Rutgers, State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Neuron 60:683-97. 2008
    ....
  23. ncbi request reprint Hippocampal CA3 pyramidal cells selectively innervate aspiny interneurons
    Lucia Wittner
    Center for Molecular and Behavioural Neuroscience, Rutgers, The State University of New Jersey, 197 University Ave, Newark, 07102, USA
    Eur J Neurosci 24:1286-98. 2006
    ..These findings indicate a strong target selection of CA3 pyramidal cells favouring the activation of aspiny classes of interneurons...
  24. ncbi request reprint Spike train dynamics predicts theta-related phase precession in hippocampal pyramidal cells
    Kenneth D Harris
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, New Jersey 07102, USA
    Nature 417:738-41. 2002
    ....
  25. pmc Intrinsic circuit organization and theta-gamma oscillation dynamics in the entorhinal cortex of the rat
    Pascale Quilichini
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    J Neurosci 30:11128-42. 2010
    ..The special wiring architecture and unique membrane properties of EC neurons may underlie their behaviorally distinct firing patterns in the waking animal...
  26. ncbi request reprint Characterization of neocortical principal cells and interneurons by network interactions and extracellular features
    Peter Bartho
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Ave, Newark, NJ 07102, USA
    J Neurophysiol 92:600-8. 2004
    ..High-density parallel recordings of neuronal activity, determination of their physical location and their classification into pyramidal and interneuron classes provide the necessary tools for local circuit analysis...
  27. pmc Spike phase precession persists after transient intrahippocampal perturbation
    Michaël B Zugaro
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    Nat Neurosci 8:67-71. 2005
    ..These findings indicate that phase advancement that emerges within hippocampal circuitry may be updated at the beginning of each theta cycle by extrahippocampal inputs...
  28. ncbi request reprint Interneuron Diversity series: Circuit complexity and axon wiring economy of cortical interneurons
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
    Trends Neurosci 27:186-93. 2004
    ..The complex wiring of diverse interneuron classes could represent an economic solution for supporting global synchrony and oscillations at multiple timescales with minimum axon length...
  29. pmc Relationships between hippocampal sharp waves, ripples, and fast gamma oscillation: influence of dentate and entorhinal cortical activity
    David Sullivan
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    J Neurosci 31:8605-16. 2011
    ..We hypothesize that each hippocampal subnetwork possesses distinct resonant properties, tuned by the magnitude of the excitatory drive...
  30. pmc Temporal delays among place cells determine the frequency of population theta oscillations in the hippocampus
    Caroline Geisler
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Proc Natl Acad Sci U S A 107:7957-62. 2010
    ....
  31. ncbi request reprint Cannabinoids reveal importance of spike timing coordination in hippocampal function
    David Robbe
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    Nat Neurosci 9:1526-33. 2006
    ..We hypothesize that reduced spike timing coordination and the associated impairment of physiological oscillations are responsible for cannabinoid-induced memory deficits...
  32. doi request reprint The origin of extracellular fields and currents--EEG, ECoG, LFP and spikes
    Gyorgy Buzsaki
    Center for Molecular and Behavioural Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, New Jersey 07102, USA
    Nat Rev Neurosci 13:407-20. 2012
    ....
  33. ncbi request reprint Theta rhythm of navigation: link between path integration and landmark navigation, episodic and semantic memory
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, 07102, USA
    Hippocampus 15:827-40. 2005
    ..Theta oscillation can hence be conceived as the navigation rhythm through both physical and mnemonic space, facilitating the formation of maps and episodic/semantic memories...
  34. pmc REM sleep reorganizes hippocampal excitability
    Andres D Grosmark
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Neuron 75:1001-7. 2012
    ..These findings assign a prominent role of REM sleep in sleep-related neuronal plasticity...
  35. pmc Diode probes for spatiotemporal optical control of multiple neurons in freely moving animals
    Eran Stark
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    J Neurophysiol 108:349-63. 2012
    ..The capacity of the system to generate unique neural activity patterns facilitates multisite manipulation of neural circuits in a closed-loop manner and opens the door to addressing novel questions...
  36. pmc Activity dynamics and behavioral correlates of CA3 and CA1 hippocampal pyramidal neurons
    Kenji Mizuseki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey, USA
    Hippocampus 22:1659-80. 2012
    ..Our findings suggest that these distinct activity dynamics of CA1 and CA3 pyramidal cells support their distinct computational roles...
  37. pmc Transcranial electric stimulation entrains cortical neuronal populations in rats
    Simal Ozen
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, New Jersey 07102, USA
    J Neurosci 30:11476-85. 2010
    ..We suggest that TES in chronic preparations may be used for experimental and therapeutic control of brain activity...
  38. pmc Alteration of theta timescale dynamics of hippocampal place cells by a cannabinoid is associated with memory impairment
    David Robbe
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
    J Neurosci 29:12597-605. 2009
    ..We hypothesize that precise temporal coordination of hippocampal neurons is necessary for guiding behavior in spatial memory tasks...
  39. pmc Hippocampal network dynamics constrain the time lag between pyramidal cells across modified environments
    Kamran Diba
    Center for Molecular and Behavioral Neuroscience, Rutgers University Newark, Newark, New Jersey 07102, USA
    J Neurosci 28:13448-56. 2008
    ..The freedoms permit the necessary flexibility for the network to distinctly represent unique patterns, whereas the dynamics constrain the speed at which activity propagates between the cell assemblies representing the patterns...
  40. pmc Hippocampal CA1 pyramidal cells form functionally distinct sublayers
    Kenji Mizuseki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey, USA
    Nat Neurosci 14:1174-81. 2011
    ..Thus, CA1 pyramidal cells in adjacent sublayers can address their targets jointly or differentially, depending on brain states...
  41. pmc Forward and reverse hippocampal place-cell sequences during ripples
    Kamran Diba
    Center for Molecular and Behavioral Neurobiology, Rutgers University, 197 University Ave, Newark, New Jersey 07102, USA
    Nat Neurosci 10:1241-2. 2007
    ..This bidirectional re-enactment of temporal sequences may contribute to the establishment of higher-order associations in episodic memory...
  42. pmc Communication between neocortex and hippocampus during sleep in rodents
    Anton Sirota
    Center for Molecular and Behavioral Neuroscience, Rutgers, State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Proc Natl Acad Sci U S A 100:2065-9. 2003
    ..We hypothesize that oscillation-mediated temporal links coordinate specific information transfer between neocortical and hippocampal cell assemblies. Such a neocortical-hippocampal interplay may be important for memory consolidation...
  43. ncbi request reprint Massively parallel recording of unit and local field potentials with silicon-based electrodes
    Jozsef Csicsvari
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    J Neurophysiol 90:1314-23. 2003
    ..Silicon technology is a promising approach for high-density, high-resolution sampling of neuronal activity in both basic research and prosthetic devices...
  44. pmc Cross-frequency phase-phase coupling between θ and γ oscillations in the hippocampus
    Mariano A Belluscio
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    J Neurosci 32:423-35. 2012
    ..We suggest that cross-frequency phase coupling can support multiple time-scale control of neuronal spikes within and across structures...
  45. pmc Three-dimensional reconstruction of the axon arbor of a CA3 pyramidal cell recorded and filled in vivo
    Lucia Wittner
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Brain Struct Funct 212:75-83. 2007
    ..This arrangement, in combination with the parallel input granule cells and parallel output CA1 pyramidal cells, appears ideal for segregation and integration of information and memories...
  46. pmc Distinct representations and theta dynamics in dorsal and ventral hippocampus
    Sebastien Royer
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    J Neurosci 30:1777-87. 2010
    ..This change is paralleled with a reduction of theta rhythm and an increased representation of nonspatial information...
  47. ncbi request reprint Two-photon imaging of brain pericytes in vivo using dextran-conjugated dyes
    Hajime Hirase
    Center for Molecular and Behavioral Neuroscience, Rutgers, State University of New Jersey, Newark, New Jersey 07102, USA
    Glia 46:95-100. 2004
    ..Selective in vivo labeling of pericytes with functional markers may help reveal their physiological function in neuronal activity-associated regulation of local cerebral blood flow...
  48. ncbi request reprint Organization of cell assemblies in the hippocampus
    Kenneth D Harris
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, New Jersey 07102, USA
    Nature 424:552-6. 2003
    ....
  49. pmc Traveling theta waves along the entire septotemporal axis of the hippocampus
    Jagdish Patel
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Neuron 75:410-7. 2012
    ..Thus, theta oscillations can temporally combine or segregate neocortical representations along the septotemporal axis of the hippocampus...
  50. pmc Behavior-dependent coordination of multiple theta dipoles in the hippocampus
    Sean M Montgomery
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, New Jersey 07102, USA
    J Neurosci 29:1381-94. 2009
    ..Moreover, our data suggest that these different theta generators flexibly coordinate hippocampal regions and layers to support behavioral task performance...
  51. pmc Theta-mediated dynamics of spatial information in hippocampus
    Vladimir Itskov
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    J Neurosci 28:5959-64. 2008
    ....
  52. pmc A 4 Hz oscillation adaptively synchronizes prefrontal, VTA, and hippocampal activities
    Shigeyoshi Fujisawa
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Neuron 72:153-65. 2011
    ..Thus, multiplexed timing mechanisms in the PFC-VTA-hippocampus axis may support processing of information, including working memory...
  53. pmc GABAergic circuits mediate the reinforcement-related signals of striatal cholinergic interneurons
    Daniel F English
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, New Jersey, USA
    Nat Neurosci 15:123-30. 2012
    ..These results reveal a previously unknown circuit mechanism that transmits reinforcement-related information of ChAT interneurons in the mouse neostriatal network...
  54. pmc Behavior-dependent short-term assembly dynamics in the medial prefrontal cortex
    Shigeyoshi Fujisawa
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, New Jersey 07102, USA
    Nat Neurosci 11:823-33. 2008
    ..Seeking potential mechanisms for such effects, we found evidence for both firing pattern-dependent facilitation and depression, as well as for a supralinear effect of presynaptic coincidence on the firing of postsynaptic targets...
  55. pmc Calcium dynamics of cortical astrocytic networks in vivo
    Hajime Hirase
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, New Jersey, USA
    PLoS Biol 2:E96. 2004
    ..These findings indicate potential neuron-glia communication in the intact brain...
  56. pmc Hippocampal place cell assemblies are speed-controlled oscillators
    Caroline Geisler
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102, USA
    Proc Natl Acad Sci U S A 104:8149-54. 2007
    ..We hypothesize that the speed-correlated acceleration of place cell assembly oscillation is responsible for the phase-distance invariance of hippocampal place cells...
  57. pmc Local generation and propagation of ripples along the septotemporal axis of the hippocampus
    Jagdish Patel
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, The Neuroscience Institute, School of Medicine and Center for Neural Science, New York University, New York, New York 10016, Physics Department, California Institute of Technology, Pasadena, California 91125, and Department of Physiology, University of Szeged, Szeged H 6720, Hungary
    J Neurosci 33:17029-41. 2013
    ..In contrast, ripples that emerged in the temporal pole broadcast largely independent information to their cortical and subcortical targets. ..
  58. doi request reprint Mechanisms of gamma oscillations
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, New Jersey 07102, USA
    Annu Rev Neurosci 35:203-25. 2012
    ..Because of their ubiquitous nature and strong correlation with the "operational modes" of local circuits, gamma oscillations continue to provide important clues about neuronal population dynamics in health and disease...
  59. pmc Gamma oscillations dynamically couple hippocampal CA3 and CA1 regions during memory task performance
    Sean M Montgomery
    Center for Molecular and Behavioral Neuroscience, Rutgers University, 197 University Avenue, Newark, NJ 07102, USA
    Proc Natl Acad Sci U S A 104:14495-500. 2007
    ..Based on these findings, we propose that gamma oscillations may serve as a physiological mechanism by which CA3 output can coordinate CA1 activity to support retrieval of hippocampus-dependent memories...
  60. ncbi request reprint Selective impairment of hippocampal gamma oscillations in connexin-36 knock-out mouse in vivo
    Derek L Buhl
    Center for Molecular and Behavioral Neuroscience, Rutgers University, The State University of New Jersey, Newark, New Jersey 07102, USA
    J Neurosci 23:1013-8. 2003
    ..This suggests that Cx36 interneuronal gap junctions selectively contribute to gamma oscillations...
  61. pmc Sequential structure of neocortical spontaneous activity in vivo
    Artur Luczak
    Center for Molecular and Behavioral Science, Rutgers University, Newark, NJ 07102, USA
    Proc Natl Acad Sci U S A 104:347-52. 2007
    ..We suggest that these stereotyped patterns arise from the interplay of intrinsic cellular conductances and local circuit properties...
  62. ncbi request reprint Klusters, NeuroScope, NDManager: a free software suite for neurophysiological data processing and visualization
    Lynn Hazan
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ 07102, USA
    J Neurosci Methods 155:207-16. 2006
    ..Also included are extensive user manuals and sample data, as well as source code and documentation...
  63. ncbi request reprint The structure of consciousness
    Gyorgy Buzsaki
    Center for Molecular and Behavioral Neuroscience, Rutgers University, 197 University Avenue, Newark, New Jersey 07102, USA
    Nature 446:267. 2007
  64. doi request reprint Closed-loop control of epilepsy by transcranial electrical stimulation
    Antal Berenyi
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Science 337:735-7. 2012
    ..Closed-loop TES can be an effective clinical tool to reduce pathological brain patterns in drug-resistant patients...
  65. pmc Predominant enhancement of glucose uptake in astrocytes versus neurons during activation of the somatosensory cortex
    Julien Chuquet
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, New Jersey 07102, USA
    J Neurosci 30:15298-303. 2010
    ....

Research Grants33

  1. Imaging Local Network Activity in Vivo
    Gyorgy Buzsaki; Fiscal Year: 2006
    ..The electric field-unit imaging methods developed and tested in the hippocampus can be applied for other cortical and subcortical structures. ..
  2. NETWORK COOPERATION IN THE HIPPOCAMPUS IN VIVO
    Gyorgy Buzsaki; Fiscal Year: 2007
    ..The dysfunction of these hypothesized, cooperative mechanisms may contribute to human diseases, such as Alzheimer's, schizophrenia and epilepsy. ..
  3. Hippocampal interneuronal network (MH 54671)
    Gyorgy Buzsaki; Fiscal Year: 2007
    ....
  4. NETWORK COOPERATION IN THE HIPPOCAMPUS IN VIVO
    Gyorgy Buzsaki; Fiscal Year: 2009
    ..Dysfunction of self-organized cellular-synaptic mechanisms may underline Alzheimer's disease, schizophrenia and other cognitive diseases. ..
  5. NETWORK COOPERATION IN THE HIPPOCAMPUS IN VIVO
    Gyorgy Buzsaki; Fiscal Year: 2010
    ..Dysfunction of self-organized cellular-synaptic mechanisms may underline Alzheimer's disease, schizophrenia and other cognitive diseases. ..
  6. Hippocampal interneuronal network (MH 54671)
    Gyorgy Buzsaki; Fiscal Year: 2010
    ....
  7. NETWORK COOPERATION IN THE HIPPOCAMPUS IN VIVO
    Gyorgy Buzsaki; Fiscal Year: 2003
    ..The results will be used to moderate conclusions based on EC data if reliability is low. Misses and FA's will be considered. ..
  8. HIPPOCAMPAL INTERNEURONAL NETWORK
    Gyorgy Buzsaki; Fiscal Year: 1999
    ..Such knowledge is essential for understanding the consequences of interneuronal damage in disease. ..
  9. CRCNS: Dynamics of the auditory cortical column
    Gyorgy Buzsaki; Fiscal Year: 2010
    ..Involvement of underrepresented groups is also a priority, and our location at Rutgers Newark allows us a unique opportunity promote diverse participation in this program. ..