L M Brzustowicz

Summary

Affiliation: Rutgers University
Country: USA

Publications

  1. pmc Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-q22
    L M Brzustowicz
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Science 288:678-82. 2000
  2. pmc Use of a quantitative trait to map a locus associated with severity of positive symptoms in familial schizophrenia to chromosome 6p
    L M Brzustowicz
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Am J Hum Genet 61:1388-96. 1997
  3. pmc Mapping of a new SGBS locus to chromosome Xp22 in a family with a severe form of Simpson-Golabi-Behmel syndrome
    L M Brzustowicz
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Am J Hum Genet 65:779-83. 1999
  4. pmc Linkage of familial schizophrenia to chromosome 13q32
    L M Brzustowicz
    Center for Molecular and Behavorial Neuroscience, Rutgers University, Newark, New Jersey 07102, USA
    Am J Hum Genet 65:1096-103. 1999
  5. pmc Tumor necrosis factor promoter haplotype associated with schizophrenia reveals a linked locus on 1q44
    V Saviouk
    Department of Genetics, Rutgers University, 604 Allison Road, Piscataway, NJ 08854 8095, USA
    Mol Psychiatry 10:375-83. 2005
  6. ncbi Association of the homeobox transcription factor, ENGRAILED 2, 3, with autism spectrum disorder
    N Gharani
    Department of Genetics, Rutgers University, Piscataway, NJ, USA
    Mol Psychiatry 9:474-84. 2004
  7. pmc Recent advances in the genetics of schizophrenia
    D M Waterwort
    Department of Genetics, Rutgers University, Piscataway, New Jersey 08854 8082, USA
    Cell Mol Life Sci 59:331-48. 2002
  8. ncbi Familial aggregation in specific language impairment
    P Tallal
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark 07102, USA
    J Speech Lang Hear Res 44:1172-82. 2001
  9. ncbi Mapping, cloning and genetic characterization of the region containing the Wilson disease gene
    K Petrukhin
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York 10032
    Nat Genet 5:338-43. 1993
  10. pmc Mapping of human microtubule-associated protein 1B in proximity to the spinal muscular atrophy locus at 5q13
    L L Lien
    Department of Genetics, Harvard Medical School, Boston, MA 02115
    Proc Natl Acad Sci U S A 88:7873-6. 1991

Collaborators

Detail Information

Publications12

  1. pmc Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-q22
    L M Brzustowicz
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Science 288:678-82. 2000
    ..50. This linkage result should provide sufficient power to allow the positional cloning of the underlying susceptibility gene...
  2. pmc Use of a quantitative trait to map a locus associated with severity of positive symptoms in familial schizophrenia to chromosome 6p
    L M Brzustowicz
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Am J Hum Genet 61:1388-96. 1997
    ..Assessment of behavioral quantitative traits may provide increased power over categorical phenotype assignment for detection of linkage in complex psychiatric disorders...
  3. pmc Mapping of a new SGBS locus to chromosome Xp22 in a family with a severe form of Simpson-Golabi-Behmel syndrome
    L M Brzustowicz
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, USA
    Am J Hum Genet 65:779-83. 1999
    ..31 and with LOD scores <-2.0 for all of Xq. These results demonstrate that neither the GPC3 gene nor other genes on Xq26 are responsible for all cases of SGBS and that a second SGBS locus resides on Xp22...
  4. pmc Linkage of familial schizophrenia to chromosome 13q32
    L M Brzustowicz
    Center for Molecular and Behavorial Neuroscience, Rutgers University, Newark, New Jersey 07102, USA
    Am J Hum Genet 65:1096-103. 1999
    ..13. These results provide independent significant evidence of linkage of a schizophrenia-susceptibility locus to markers on 13q32 and support the presence of a second susceptibility locus on 8p21...
  5. pmc Tumor necrosis factor promoter haplotype associated with schizophrenia reveals a linked locus on 1q44
    V Saviouk
    Department of Genetics, Rutgers University, 604 Allison Road, Piscataway, NJ 08854 8095, USA
    Mol Psychiatry 10:375-83. 2005
    ....
  6. ncbi Association of the homeobox transcription factor, ENGRAILED 2, 3, with autism spectrum disorder
    N Gharani
    Department of Genetics, Rutgers University, Piscataway, NJ, USA
    Mol Psychiatry 9:474-84. 2004
    ..0024). These data demonstrate association between a cerebellar patterning gene and ASD, suggesting a role for EN2 as a susceptibility locus and supporting a neurodevelopmental defect hypothesis in the etiology of autism...
  7. pmc Recent advances in the genetics of schizophrenia
    D M Waterwort
    Department of Genetics, Rutgers University, Piscataway, New Jersey 08854 8082, USA
    Cell Mol Life Sci 59:331-48. 2002
    ..A greater understanding of disease mechanisms and the application of pharmacogenetics should also lead to improvements in therapeutic interventions...
  8. ncbi Familial aggregation in specific language impairment
    P Tallal
    Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark 07102, USA
    J Speech Lang Hear Res 44:1172-82. 2001
    ..However, case-by-case analyses showed poor intrasubject agreement on classification as language impaired on the basis of current testing as compared to history information...
  9. ncbi Mapping, cloning and genetic characterization of the region containing the Wilson disease gene
    K Petrukhin
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York 10032
    Nat Genet 5:338-43. 1993
    ..Our haplotype and mutation analyses predict that approximately half of all WD mutations will be rare in the American and Russian populations...
  10. pmc Mapping of human microtubule-associated protein 1B in proximity to the spinal muscular atrophy locus at 5q13
    L L Lien
    Department of Genetics, Harvard Medical School, Boston, MA 02115
    Proc Natl Acad Sci U S A 88:7873-6. 1991
    ..These mapping data together with the postulated role of MAP-1B in neuronal morphogenesis and its localization in anterior horn motor neurons suggest a possible association with SMA...
  11. ncbi The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene
    R E Tanzi
    Neurology Department, Harvard Medical School, Boston, Massachusetts 02114
    Nat Genet 5:344-50. 1993
    ....
  12. ncbi A posterior probability of linkage-based re-analysis of schizophrenia data yields evidence of linkage to chromosomes 1 and 17
    M W Logue
    Program for Public Health Genetics, Center for Statistical Genetics Research, Iowa City, IA 52242, USA
    Hum Hered 62:47-54. 2006
    ..8 [Brzustowicz et al. 2000]. In the current study, we revisited this data set using a Bayesian linkage analysis technique, namely the posterior probability of linkage (PPL)...