Adrienne T Black

Summary

Affiliation: Rutgers University
Country: USA

Publications

  1. pmc UVB light regulates expression of antioxidants and inflammatory mediators in human corneal epithelial cells
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Biochem Pharmacol 81:873-80. 2011
  2. pmc Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with inflammation and DNA damage
    Laurie B Joseph
    Department of Pharmacology, Rutgers University, Piscataway, NJ, United States
    Exp Mol Pathol 91:515-27. 2011
  3. ncbi Modulation of keratinocyte expression of antioxidants by 4-hydroxynonenal, a lipid peroxidation end product
    Ruijin Zheng
    Pharmacology and Toxicology and Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, USA
    Toxicol Appl Pharmacol 275:113-21. 2014
  4. pmc Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to paraquat
    Adrienne T Black
    Department of Pharmacology and Toxicology, Rutgers University, USA
    Toxicol Appl Pharmacol 231:384-92. 2008
  5. pmc Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ 08854, USA
    Toxicol Appl Pharmacol 249:178-87. 2010
  6. ncbi The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard
    Ruijin Zheng
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA
    Toxicol Appl Pharmacol 272:345-55. 2013
  7. pmc Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA
    Toxicol Appl Pharmacol 253:112-20. 2011
  8. pmc Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA
    Toxicol Appl Pharmacol 245:352-60. 2010
  9. pmc UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes
    Adrienne T Black
    Department of Pharmacology and Toxicology, Rutgers University, USA
    Toxicol Appl Pharmacol 232:14-24. 2008
  10. ncbi Oxidants and antioxidants in sulfur mustard-induced injury
    Jeffrey D Laskin
    Department of Environmental and Occupation Medicine, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
    Ann N Y Acad Sci 1203:92-100. 2010

Collaborators

Detail Information

Publications12

  1. pmc UVB light regulates expression of antioxidants and inflammatory mediators in human corneal epithelial cells
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Biochem Pharmacol 81:873-80. 2011
    ..Alterations in expression of these mediators are likely to be important in regulating inflammation and protecting the cornea from UVB-induced oxidative stress...
  2. pmc Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with inflammation and DNA damage
    Laurie B Joseph
    Department of Pharmacology, Rutgers University, Piscataway, NJ, United States
    Exp Mol Pathol 91:515-27. 2011
    ..X. These findings are consistent with the pathophysiology of SM-induced skin injury in humans suggesting that the hairless mouse can be used to investigate the dermatoxicity of vesicants and the potential efficacy of countermeasures...
  3. ncbi Modulation of keratinocyte expression of antioxidants by 4-hydroxynonenal, a lipid peroxidation end product
    Ruijin Zheng
    Pharmacology and Toxicology and Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, USA
    Toxicol Appl Pharmacol 275:113-21. 2014
    ..Changes in expression of keratinocyte antioxidants may be important in protecting the skin from oxidative stress...
  4. pmc Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to paraquat
    Adrienne T Black
    Department of Pharmacology and Toxicology, Rutgers University, USA
    Toxicol Appl Pharmacol 231:384-92. 2008
    ..These intracellular proteins may be important in protecting the skin from paraquat-mediated cytotoxicity...
  5. pmc Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ 08854, USA
    Toxicol Appl Pharmacol 249:178-87. 2010
    ..These effects are similar to human responses to vesicants in vivo and suggest that the full thickness skin equivalent is a useful in vitro model to characterize the biological effects of mustards and to develop potential therapeutics...
  6. ncbi The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard
    Ruijin Zheng
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA
    Toxicol Appl Pharmacol 272:345-55. 2013
    ..The sensitivity of corneal epithelial cells to oxidative stress may be an important mechanism mediating tissue injury induced by UVB or nitrogen mustard...
  7. pmc Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA
    Toxicol Appl Pharmacol 253:112-20. 2011
    ..These data suggest that MAP kinases regulate Hsp 27 and Hsp70; moreover, caveolae-mediated regulation of heat shock protein expression may be important in the pathophysiology of vesicant-induced skin toxicity...
  8. pmc Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA
    Toxicol Appl Pharmacol 245:352-60. 2010
    ..Inhibiting the capacity of keratinocytes to generate eicosanoids may be important in limiting inflammation and protecting the skin from vesicant-induced oxidative stress and injury...
  9. pmc UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes
    Adrienne T Black
    Department of Pharmacology and Toxicology, Rutgers University, USA
    Toxicol Appl Pharmacol 232:14-24. 2008
    ..Moreover, both the capacity of keratinocytes to generate prostaglandins and their ability to respond to these lipid mediators are stimulated by exposure to UVB...
  10. ncbi Oxidants and antioxidants in sulfur mustard-induced injury
    Jeffrey D Laskin
    Department of Environmental and Occupation Medicine, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
    Ann N Y Acad Sci 1203:92-100. 2010
    ..These data indicate that drugs that target oxidative stress pathways may represent important candidates for reducing SM-induced tissue injury...
  11. ncbi Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid
    Ruijin Zheng
    Pharmacology and Toxicology and Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ 08854, USA
    Free Radic Biol Med 67:1-9. 2014
    ..These data indicate that nitrofatty acids are effective signaling molecules in keratinocytes. Moreover, caveolae seem to be important in the localization of stress proteins in response to nitrofatty acids. ..
  12. pmc Distinct effects of ultraviolet B light on antioxidant expression in undifferentiated and differentiated mouse keratinocytes
    Adrienne T Black
    Department of Pharmacology and Toxicology, Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Carcinogenesis 29:219-25. 2008
    ..Moreover, MAP kinases are critical regulators of this response. Alterations in antioxidants are likely to be important mechanisms for protecting the skin from UVB-induced oxidative stress...