Adrienne T Black

Summary

Affiliation: Rutgers University
Country: USA

Publications

  1. ncbi UVB light regulates expression of antioxidants and inflammatory mediators in human corneal epithelial cells
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Biochem Pharmacol 81:873-80. 2011
  2. ncbi Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with inflammation and DNA damage
    Laurie B Joseph
    Department of Pharmacology, Rutgers University, Piscataway, NJ, United States
    Exp Mol Pathol 91:515-27. 2011
  3. ncbi Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to paraquat
    Adrienne T Black
    Department of Pharmacology and Toxicology, Rutgers University, USA
    Toxicol Appl Pharmacol 231:384-92. 2008
  4. ncbi Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ 08854, USA
    Toxicol Appl Pharmacol 249:178-87. 2010
  5. ncbi Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA
    Toxicol Appl Pharmacol 253:112-20. 2011
  6. ncbi UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes
    Adrienne T Black
    Department of Pharmacology and Toxicology, Rutgers University, USA
    Toxicol Appl Pharmacol 232:14-24. 2008
  7. ncbi Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA
    Toxicol Appl Pharmacol 245:352-60. 2010
  8. ncbi Oxidants and antioxidants in sulfur mustard-induced injury
    Jeffrey D Laskin
    Department of Environmental and Occupation Medicine, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
    Ann N Y Acad Sci 1203:92-100. 2010
  9. ncbi Distinct effects of ultraviolet B light on antioxidant expression in undifferentiated and differentiated mouse keratinocytes
    Adrienne T Black
    Department of Pharmacology and Toxicology, Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Carcinogenesis 29:219-25. 2008

Collaborators

Detail Information

Publications9

  1. ncbi UVB light regulates expression of antioxidants and inflammatory mediators in human corneal epithelial cells
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Biochem Pharmacol 81:873-80. 2011
    ..Alterations in expression of these mediators are likely to be important in regulating inflammation and protecting the cornea from UVB-induced oxidative stress...
  2. ncbi Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with inflammation and DNA damage
    Laurie B Joseph
    Department of Pharmacology, Rutgers University, Piscataway, NJ, United States
    Exp Mol Pathol 91:515-27. 2011
    ..X. These findings are consistent with the pathophysiology of SM-induced skin injury in humans suggesting that the hairless mouse can be used to investigate the dermatoxicity of vesicants and the potential efficacy of countermeasures...
  3. ncbi Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to paraquat
    Adrienne T Black
    Department of Pharmacology and Toxicology, Rutgers University, USA
    Toxicol Appl Pharmacol 231:384-92. 2008
    ..These intracellular proteins may be important in protecting the skin from paraquat-mediated cytotoxicity...
  4. ncbi Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ 08854, USA
    Toxicol Appl Pharmacol 249:178-87. 2010
    ..These effects are similar to human responses to vesicants in vivo and suggest that the full thickness skin equivalent is a useful in vitro model to characterize the biological effects of mustards and to develop potential therapeutics...
  5. ncbi Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA
    Toxicol Appl Pharmacol 253:112-20. 2011
    ..These data suggest that MAP kinases regulate Hsp 27 and Hsp70; moreover, caveolae-mediated regulation of heat shock protein expression may be important in the pathophysiology of vesicant-induced skin toxicity...
  6. ncbi UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes
    Adrienne T Black
    Department of Pharmacology and Toxicology, Rutgers University, USA
    Toxicol Appl Pharmacol 232:14-24. 2008
    ..Moreover, both the capacity of keratinocytes to generate prostaglandins and their ability to respond to these lipid mediators are stimulated by exposure to UVB...
  7. ncbi Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide
    Adrienne T Black
    Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA
    Toxicol Appl Pharmacol 245:352-60. 2010
    ..Inhibiting the capacity of keratinocytes to generate eicosanoids may be important in limiting inflammation and protecting the skin from vesicant-induced oxidative stress and injury...
  8. ncbi Oxidants and antioxidants in sulfur mustard-induced injury
    Jeffrey D Laskin
    Department of Environmental and Occupation Medicine, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
    Ann N Y Acad Sci 1203:92-100. 2010
    ..These data indicate that drugs that target oxidative stress pathways may represent important candidates for reducing SM-induced tissue injury...
  9. ncbi Distinct effects of ultraviolet B light on antioxidant expression in undifferentiated and differentiated mouse keratinocytes
    Adrienne T Black
    Department of Pharmacology and Toxicology, Rutgers University, 170 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Carcinogenesis 29:219-25. 2008
    ..Moreover, MAP kinases are critical regulators of this response. Alterations in antioxidants are likely to be important mechanisms for protecting the skin from UVB-induced oxidative stress...