Research Topics
| K Y SmithSummaryAffiliation: Rush University Medical Center Country: USA Publications
Research Grants
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Detail Information
Publications
Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapyK Y Smith
Section of Infectious Diseases, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
J Infect Dis 181:141-7. 2000..These findings suggest that there is a complex relationship among the thymus, viral replication, and lymphocyte restoration after application of HAART in HIV disease...
Initiating antiretroviral therapy in asymptomatic HIV patientsKimberly Y Smith
Rush Medical College, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60614, USA
J Natl Med Assoc 96:13S-16S. 2004
Disparities and gaps in HIV research and careKimberly Y Smith
Rush Medical College, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60614, USA
J Natl Med Assoc 96:5S-7S. 2004
Optimizing care for African-American HIV-positive patientsKimberly Y Smith
Rush Medical College and Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
AIDS Patient Care STDS 17:527-38. 2003....
Protease inhibitor-sparing regimensKimberly Y Smith
Department of Medicine, Rush Medical College, Rush-Presbyterian-St. Luke's Medical Center, Chicago, USA
J Int Assoc Physicians AIDS Care (Chic Ill) 1:116-20. 2002
Treatment with recombinant growth hormone is associated with modest improvement in CD4 lymphocyte reconstitution in HIV-infected persons on antiretroviral therapy: results of ACTG A5174Kimberly Smith
Section of Infectious Diseases, Rush University Medical Center, Chicago, Illinois 60612, USA
AIDS Res Hum Retroviruses 26:425-32. 2010..Treatment with rhGH +ART may be associated with modest increases in CD4 lymphocytes over ART alone in subjects with CD4 <350, yet the origin of these naive cells and their impact on immune function require further investigation...
Selected metabolic and morphologic complications associated with highly active antiretroviral therapyKimberly Y Smith
Section of Infectious Diseases, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
J Infect Dis 185:S123-7. 2002..Treatment regimens directed at these abnormalities are being developed, but clinical trials are needed to fully ascertain the efficacy and safety of such interventions...
T cell receptor excision circle (TREC) content following maximum HIV suppression is equivalent in HIV-infected and HIV-uninfected individualsC M Steffens
Department of Immunology/Microbiology, Rush-Presbyterian-St Luke's Medical Center, Chicago, Illinois 60612, USA
AIDS 15:1757-64. 2001....
Evaluation of the impact of highly active antiretroviral therapy on immune recovery in antiretroviral naive patientsL Al-Harthi
Department of Immunology Microbiology, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
HIV Med 5:55-65. 2004..To examine the extent of immune reconstitution in treatment-naive patients with CD4 T-cell counts <500 cells/microL following 48 weeks of highly active antiretroviral therapy (HAART)...
Randomized, double-blind, placebo-matched, multicenter trial of abacavir/lamivudine or tenofovir/emtricitabine with lopinavir/ritonavir for initial HIV treatmentKimberly Y Smith
Rush University Medical Center, Chicago, Illinois 60612, USA
AIDS 23:1547-56. 2009..This is the first completed, randomized clinical trial to directly compare the efficacy, safety, and tolerability of these agents, each in combination with lopinavir/ritonavir in antiretroviral-naive patients...
HIV-1-infected antiretroviral-treated patients with prolonged partial viral suppression: clinical, virologic, and immunologic courseAllan R Tenorio
Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
J Acquir Immune Defic Syndr 34:491-6. 2003..HIV-specific CD4+ T-cell immunity was detected in most subjects with low-level and undetectable viremia and may have a role in controlling viremia in the setting of partial suppression...
Classic pyomyositis of the extremities as an unusual manifestation of Blastomyces dermatitidis: a report of two casesMichael Y Lin
Section of Infectious Diseases, Rush University Medical Center, Chicago, IL 60612, USA
Mycoses 53:356-9. 2010..dermatitidis, particularly of the extremity muscles, is unique. We conclude that B. dermatitidis is a potential cause of classic pyomyositis...
A pilot study of the safety and efficacy of cholestin in treating HIV-related dyslipidemiaJoyce K Keithley
Rush University College of Nursing, Chicago, Illinois 60612, USA
Nutrition 18:201-4. 2002..We collected preliminary safety and efficacy data on the effects of Cholestin, a statin-containing dietary supplement, in individuals with dsylipidemia related to human immunodeficiency virus...
Electron beam computed tomography for assessment of coronary artery disease in HIV-infected men receiving antiretroviral therapyRohit Talwani
Section of Infectious Diseases, Department of Medicine, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60612, USA
J Acquir Immune Defic Syndr 30:191-5. 2002..These results need to be confirmed in larger long-term studies, with controls well matched for coronary risk factors...
Recognizing and managing common toxicities in patients receiving antiretroviral therapyM Keith Rawlings
Peabody Health Center, Dallas, Texas, USA
AIDS Read 14:S12-5. 2004..An understanding of the drug-specific, class-specific, and general toxicities and side effects of antiretroviral drugs will help the clinician tailor treatment regimens to individual patients...
Role of Baseline pol Genotype in HIV-1 Fitness EvolutionJan Weber
Department of Virology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Acquir Immune Defic Syndr 33:448-60. 2003..65, P < 0.0001). However, our results suggest that the preexistence of secondary mutations in protease genetic background may have implications in HIV-1 fitness evolution and virologic response to antiretroviral therapy...
Limited immune restoration after 3 years' suppression of HIV-1 replication in patients with moderately advanced diseaseHernan Valdez
Case Western Reserve University, University Hospitals of Cleveland Center for AIDS Research, Ohio, USA
AIDS 16:1859-66. 2002..The clinical significance of incomplete reconstitution of CD4 lymphocyte number, phenotype, and proliferative function in HIV-1 infection remains to be determined...
Immune reconstitution after successful treatment with protease inhibitor-based and protease inhibitor-sparing antiretroviral regimensKimberly Y Smith
J Acquir Immune Defic Syndr 29:544-5. 2002
Improving adherence to HAARTValerie E Stone
Massachusetts General Hospital, Boston, MA 02114, USA
J Natl Med Assoc 96:27S-29S. 2004
CCR5 and CXCR4 expression after highly active antiretroviral therapy (HAART)Kimberly Y Smith
J Acquir Immune Defic Syndr 30:458-60. 2002
Research Grants
- Growth Hormone and Immune Reconstitution in HIV DiseaseKimberly Smith; Fiscal Year: 2004..abstract_text> ..
