J M Plate

Summary

Affiliation: Rush University Medical Center
Country: USA

Publications

  1. ncbi Major histocompatibility complex class I-related chain A/B (MICA/B) expression in tumor tissue and serum of pancreatic cancer: role of uric acid accumulation in gemcitabine-induced MICA/B expression
    Xiulong Xu
    Department of General Surgery, Rush University Medical Center, Chicago, IL 60612, USA
    BMC Cancer 11:194. 2011
  2. ncbi Clinical trials of vaccines for immunotherapy in pancreatic cancer
    Janet Plate
    Division of Hematology, Oncology and Cell Therapy, Section of Medical Oncology, Rush University Medical Center, Chicago, IL 60612, USA
    Expert Rev Vaccines 10:825-36. 2011
  3. ncbi Current immunotherapeutic strategies in pancreatic cancer
    Janet M D Plate
    Division of Oncology and Hematology, Department of Immunology Microbiology, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Surg Oncol Clin N Am 16:919-43, xi. 2007
  4. ncbi Effect of gemcitabine on immune cells in subjects with adenocarcinoma of the pancreas
    Janet M D Plate
    Division of Oncology and Hematology, Department of Medicine, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Cancer Immunol Immunother 54:915-25. 2005
  5. ncbi Immunobiotherapy directed against mutated and aberrantly expressed gene products in pancreas cancer
    Janet M D Plate
    Division of Hematology and Oncology, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Cell Biochem 94:1069-77. 2005
  6. ncbi PI3-kinase regulates survival of chronic lymphocytic leukemia B-cells by preventing caspase 8 activation
    Janet M D Plate
    Department of Medicine, Section of Medical Oncology, Rush University Medical Center, Chicago, IL 60612, USA
    Leuk Lymphoma 45:1519-29. 2004
  7. ncbi Immune cell functions in pancreatic cancer
    J M Plate
    Section of Medical Oncology, Rush Cancer Institute, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Crit Rev Immunol 20:375-92. 2000
  8. ncbi Gene expression in chronic lymphocytic leukemia B cells and changes during induction of apoptosis
    J M Plate
    Rush Presbyterian St Luke s Medical Center, Chicago, Ill 60612, USA
    Exp Hematol 28:1214-24. 2000
  9. ncbi Immunoregulation in pancreatic cancer patients
    J M Plate
    Section of Medical Oncology, Department of Medicine, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Cancer Immunol Immunother 48:270-9. 1999
  10. ncbi Mycobacterium avium complex activates nuclear factor kappaB via induction of inflammatory cytokines
    M Ghassemi
    Department of Medicine, University of Illinois, Chicago, Illinois, 60612, USA
    Cell Immunol 191:117-23. 1999

Collaborators

  • M Ghassemi
  • Xiulong Xu
  • Veronika Groh
  • Geetha S Rao
  • Howard L Kaufman
  • Richard A Prinz
  • Thomas Spies
  • Paolo Gattuso

Detail Information

Publications10

  1. ncbi Major histocompatibility complex class I-related chain A/B (MICA/B) expression in tumor tissue and serum of pancreatic cancer: role of uric acid accumulation in gemcitabine-induced MICA/B expression
    Xiulong Xu
    Department of General Surgery, Rush University Medical Center, Chicago, IL 60612, USA
    BMC Cancer 11:194. 2011
    ..In this study, we sought to study MICA/B expression in pancreatic cancer and to determine whether and how genotoxic drugs such as gemcitabine can affect MICA/B expression and natural killer cytotoxity...
  2. ncbi Clinical trials of vaccines for immunotherapy in pancreatic cancer
    Janet Plate
    Division of Hematology, Oncology and Cell Therapy, Section of Medical Oncology, Rush University Medical Center, Chicago, IL 60612, USA
    Expert Rev Vaccines 10:825-36. 2011
    ..Current cancer trials for pancreatic cancer patients are discussed in this article...
  3. ncbi Current immunotherapeutic strategies in pancreatic cancer
    Janet M D Plate
    Division of Oncology and Hematology, Department of Immunology Microbiology, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Surg Oncol Clin N Am 16:919-43, xi. 2007
    ..Finally, the article discusses the choices of a variety of clinical trials using immune modulation for patients with pancreatic cancer...
  4. ncbi Effect of gemcitabine on immune cells in subjects with adenocarcinoma of the pancreas
    Janet M D Plate
    Division of Oncology and Hematology, Department of Medicine, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Cancer Immunol Immunother 54:915-25. 2005
    ....
  5. ncbi Immunobiotherapy directed against mutated and aberrantly expressed gene products in pancreas cancer
    Janet M D Plate
    Division of Hematology and Oncology, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Cell Biochem 94:1069-77. 2005
    ..Immunobiotherapy intervention of pancreas cancer must circumvent these obstacles and integrate effective immunotherapy with molecularly targeted approaches to pancreas cancer intervention...
  6. ncbi PI3-kinase regulates survival of chronic lymphocytic leukemia B-cells by preventing caspase 8 activation
    Janet M D Plate
    Department of Medicine, Section of Medical Oncology, Rush University Medical Center, Chicago, IL 60612, USA
    Leuk Lymphoma 45:1519-29. 2004
    ..The data further support the hypothesis that signal transducing, membrane associated receptors triggered by extrinsic factors, maintain CLL leukemic B-cell survival in vivo by preventing caspase activation...
  7. ncbi Immune cell functions in pancreatic cancer
    J M Plate
    Section of Medical Oncology, Rush Cancer Institute, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Crit Rev Immunol 20:375-92. 2000
    ..Unless the problem of tumor-derived immunosuppressive products is addressed directly through basic and translational research studies, successful biotherapeutic treatment for pancreatic cancer may not be forthcoming...
  8. ncbi Gene expression in chronic lymphocytic leukemia B cells and changes during induction of apoptosis
    J M Plate
    Rush Presbyterian St Luke s Medical Center, Chicago, Ill 60612, USA
    Exp Hematol 28:1214-24. 2000
    ..Fludara enhances kinetics of apoptosis and induces expression of a gene responsive to stress that regulates expression of a kinase involved in initiation of the apoptotic pathway...
  9. ncbi Immunoregulation in pancreatic cancer patients
    J M Plate
    Section of Medical Oncology, Department of Medicine, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Cancer Immunol Immunother 48:270-9. 1999
    ....
  10. ncbi Mycobacterium avium complex activates nuclear factor kappaB via induction of inflammatory cytokines
    M Ghassemi
    Department of Medicine, University of Illinois, Chicago, Illinois, 60612, USA
    Cell Immunol 191:117-23. 1999
    ..The rapid induction of TNFalpha may be important in the initial host response to MAC infection...