Andres M Kanner

Summary

Affiliation: Rush University Medical Center
Country: USA

Publications

  1. ncbi request reprint Rapid detection of major depression in epilepsy: a multicentre study
    Frank G Gilliam
    Department of Neurology, The Neurological Institute, Columbia University, New York, USA
    Lancet Neurol 5:399-405. 2006
  2. ncbi request reprint Diagnosis and management of depression and psychosis in children and adolescents with epilepsy
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Chicago, IL 60612, USA
    J Child Neurol 19:S65-72. 2004
  3. doi request reprint Management of newly diagnosed epilepsy: a practical guide to monotherapy
    Michael A Stein
    Department of Neurological Sciences, Rush University Medical Centre, Chicago, Illinois 60612, USA
    Drugs 69:199-222. 2009
  4. ncbi request reprint Is major depression a neurologic disorder with psychiatric symptoms?
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush University Medical Center, Chicago, IL, USA
    Epilepsy Behav 5:636-44. 2004
  5. ncbi request reprint Prevalence and clinical characteristics of postictal psychiatric symptoms in partial epilepsy
    Andres M Kanner
    Division of Epilepsy, Department of Neurological Sciences, Rush Medical College, Rush University Medical Center, Chicago, IL, USA
    Neurology 62:708-13. 2004
  6. ncbi request reprint Depression in epilepsy: a frequently neglected multifaceted disorder
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Chicago, IL, USA
    Epilepsy Behav 4:11-9. 2003
  7. ncbi request reprint The impact of mood disorders in neurological diseases: should neurologists be concerned?
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Epilepsy Behav 4:S3-13. 2003
  8. ncbi request reprint Depression and the risk of neurological disorders
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush University Medical Center, Chicago, IL 60612, USA
    Lancet 366:1147-8. 2005
  9. doi request reprint Depression and epilepsy, pain and psychogenic non-epileptic seizures: clinical and therapeutic perspectives
    Andres M Kanner
    Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Epilepsy Behav 24:169-81. 2012
  10. doi request reprint Depressive and anxiety disorders in epilepsy: do they differ in their potential to worsen common antiepileptic drug-related adverse events?
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Chicago, Illinois 60612, USA
    Epilepsia 53:1104-8. 2012

Collaborators

Detail Information

Publications56

  1. ncbi request reprint Rapid detection of major depression in epilepsy: a multicentre study
    Frank G Gilliam
    Department of Neurology, The Neurological Institute, Columbia University, New York, USA
    Lancet Neurol 5:399-405. 2006
    ..Depression is a common comorbid disorder in epilepsy but is not routinely assessed in neurology clinics. We aimed to create a rapid yet accurate screening instrument for major depression in people with epilepsy...
  2. ncbi request reprint Diagnosis and management of depression and psychosis in children and adolescents with epilepsy
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Chicago, IL 60612, USA
    J Child Neurol 19:S65-72. 2004
    ..Although both antidepressants and antipsychotic drugs have the potential to lower the seizure threshold and increase seizures, careful drug selection, dosing, and slow titration can minimize this risk, allowing treatment to proceed...
  3. doi request reprint Management of newly diagnosed epilepsy: a practical guide to monotherapy
    Michael A Stein
    Department of Neurological Sciences, Rush University Medical Centre, Chicago, Illinois 60612, USA
    Drugs 69:199-222. 2009
    ..Finally, this information is conveniently summarized in a set of tables and illustrated by way of case scenarios...
  4. ncbi request reprint Is major depression a neurologic disorder with psychiatric symptoms?
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush University Medical Center, Chicago, IL, USA
    Epilepsy Behav 5:636-44. 2004
    ..This article reviews these data and provides evidence that major depressive and bipolar disorders may in fact be neurologic disorders with psychiatric symptoms...
  5. ncbi request reprint Prevalence and clinical characteristics of postictal psychiatric symptoms in partial epilepsy
    Andres M Kanner
    Division of Epilepsy, Department of Neurological Sciences, Rush Medical College, Rush University Medical Center, Chicago, IL, USA
    Neurology 62:708-13. 2004
    ....
  6. ncbi request reprint Depression in epilepsy: a frequently neglected multifaceted disorder
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Chicago, IL, USA
    Epilepsy Behav 4:11-9. 2003
    ....
  7. ncbi request reprint The impact of mood disorders in neurological diseases: should neurologists be concerned?
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Epilepsy Behav 4:S3-13. 2003
    ....
  8. ncbi request reprint Depression and the risk of neurological disorders
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush University Medical Center, Chicago, IL 60612, USA
    Lancet 366:1147-8. 2005
  9. doi request reprint Depression and epilepsy, pain and psychogenic non-epileptic seizures: clinical and therapeutic perspectives
    Andres M Kanner
    Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Epilepsy Behav 24:169-81. 2012
    ..Thus, clinicians have had to adopt data from patients with primary depressive disorders. We outline a consensus strategy on the identification and treatment of depressive disorders in adult and pediatric patients with epilepsy...
  10. doi request reprint Depressive and anxiety disorders in epilepsy: do they differ in their potential to worsen common antiepileptic drug-related adverse events?
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Chicago, Illinois 60612, USA
    Epilepsia 53:1104-8. 2012
    ..To compare the effect of anxiety disorders, major depressive episodes (MDEs), and subsyndromic depressive episodes (SSDEs) on antiepileptic drug (AED)-related adverse events (AEs) in persons with epilepsy (PWE)...
  11. doi request reprint Depression and epilepsy: epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrence
    Andres M Kanner
    Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Epilepsy Behav 24:156-68. 2012
    ..The negative impact of depression on the control of seizure disorders has been documented in various studies. In this manuscript, these data are reviewed and potential mechanisms explaining this phenomenon are proposed...
  12. pmc Mood disorder and epilepsy: a neurobiologic perspective of their relationship
    Andres M Kanner
    Rush Medical College, Rush University Medical Center, Chicago, Illinois 60612, USA
    Dialogues Clin Neurosci 10:39-45. 2008
    ..Indeed, patients with a history of mood disorders are twice as likely to develop pharmacoresistant epilepsy as those without such a history. These data are reviewed in this article...
  13. doi request reprint Medically intractable temporal lobe epilepsy in patients with normal MRI: surgical outcome in twenty-one consecutive patients
    Adam P Smith
    Department of Neurosurgery, Rush University Medical Center, Chicago, IL 60612, USA
    Seizure 20:475-9. 2011
    ..5 T MRI. Specifically, factors that may be associated with favorable post-surgical seizure outcome are evaluated...
  14. doi request reprint Anxiety disorders, subsyndromic depressive episodes, and major depressive episodes: do they differ on their impact on the quality of life of patients with epilepsy?
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Chicago, Illinois 60612, USA
    Epilepsia 51:1152-8. 2010
    ....
  15. ncbi request reprint Long-term significance of postictal psychotic episodes II. Are they predictive of interictal psychotic episodes?
    Andres M Kanner
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Epilepsy Behav 12:154-6. 2008
    ..The aim of this study was to determine whether postictal psychotic episodes (PIPE) are predictive of the development of interictal psychotic episodes (IPE)...
  16. ncbi request reprint The complex epilepsy patient: intricacies of assessment and treatment
    Andres M Kanner
    Laboratory of Electroencephalography and Video EEG Telemetry, Department of Neurological Science, Rush Presbyterian St Luke s Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, U S A
    Epilepsia 44:3-8. 2003
    ..Clearly, treating epilepsy is not only about controlling seizures...
  17. doi request reprint Depression in epilepsy: a complex relation with unexpected consequences
    Andres M Kanner
    Department of Neurological Sciences and Psychiatry, Rush Medical College, Laboratory of Electroencephalography and Video EEG Telemetry, Rush University Medical Center, Chicago, Illinois 60612, USA
    Curr Opin Neurol 21:190-4. 2008
    ..The recent significant increase in research on depressive disorders in epilepsy has led to a greater recognition of its negative impact on multiple aspects of these patients' lives. Thus, a review of this topic could not be timelier...
  18. doi request reprint The use of psychotropic drugs in epilepsy: what every neurologist should know
    Andres M Kanner
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Semin Neurol 28:379-88. 2008
    ..This article provides a practical review of the use of antidepressants, central nervous system stimulants, and antipsychotic drugs in patients with epilepsy...
  19. doi request reprint Pharmacodynamic and pharmacokinetic interactions of psychotropic drugs with antiepileptic drugs
    Andres M Kanner
    Rush University Medical Center, Chicago, Illinois, USA
    Int Rev Neurobiol 83:397-416. 2008
    ..This chapter provides a practical review on the use of psychotropic drugs for the treatment of these psychiatric co-morbidities in patients with epilepsy...
  20. ncbi request reprint Recognition of the various expressions of anxiety, psychosis, and aggression in epilepsy
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center at Rush University Medical Center, Chicago, Illinois 60612, USA
    Epilepsia 45:22-7. 2004
    ..In this article, three case studies are presented to illustrate the importance of distinguishing psychiatric symptoms of anxiety, psychosis, and aggression, with respect to their temporal relation with seizure occurrence...
  21. ncbi request reprint Epilepsy and mood disorders
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Rush University Medical Center, Chicago, Illinois 60612, USA
    Epilepsia 48:20-2. 2007
    ....
  22. ncbi request reprint Structural MRI changes of the brain in depression
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
    Clin EEG Neurosci 35:46-52. 2004
    ..The purpose of this article is to briefly review the published data on neuroanatomical structural changes associated with major depressive and bipolar disorders...
  23. doi request reprint Psychiatric issues in epilepsy: the complex relation of mood, anxiety disorders, and epilepsy
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, 1653 West Congress Parkway, Chicago, IL, USA
    Epilepsy Behav 15:83-7. 2009
    ..The significance of such a relation is not only theoretical, but has a marked impact on the response to pharmacological and surgical treatment of seizure disorders...
  24. ncbi request reprint Depression and epilepsy: do glucocorticoids and glutamate explain their relationship?
    Andres M Kanner
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Curr Neurol Neurosci Rep 9:307-12. 2009
    ..The abnormal role of the hypothalamic-pituitary-adrenal axis is one of the common pathogenic mechanisms that explains why patients with depression are at greater risk for developing epilepsy and vice versa...
  25. ncbi request reprint Long-term significance of postictal psychotic episodes I. Are they predictive of bilateral ictal foci?
    Andres M Kanner
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Epilepsy Behav 12:150-3. 2008
    ..The aim of this study was to determine the degree to which postictal psychotic episodes (PIPE) are predictive of bilateral independent ictal foci...
  26. doi request reprint Common errors made in the diagnosis and treatment of epilepsy
    Andres M Kanner
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Semin Neurol 28:364-78. 2008
    ..In addition to a discussion of the reasons for the errors, the article provides practical solutions...
  27. ncbi request reprint Depression in epilepsy: prevalence, clinical semiology, pathogenic mechanisms, and treatment
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Chicago, Illinois 60612, USA
    Biol Psychiatry 54:388-98. 2003
    ..Despite its relatively high prevalence, depression remains unrecognized and untreated, and unfortunately its treatment is based on empirical and uncontrolled data...
  28. ncbi request reprint When did neurologists and psychiatrists stop talking to each other?
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Chicago, IL, USA
    Epilepsy Behav 4:597-601. 2003
    ..The purpose of this paper is to highlight this bizarre phenomenon and to identify some of the reasons behind it...
  29. ncbi request reprint A past psychiatric history may be a risk factor for topiramate-related psychiatric and cognitive adverse events
    Andres M Kanner
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Rush Medical College, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Epilepsy Behav 4:548-52. 2003
    ....
  30. ncbi request reprint Should neurologists be trained to recognize and treat comorbid depression of neurologic disorders? Yes
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center and Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL, USA
    Epilepsy Behav 6:303-11. 2005
    ....
  31. ncbi request reprint Chronic epilepsy due to low grade temporal lobe tumors and due to hippocampal sclerosis: do they differ in post-surgical outcome?
    Prasad S S V Vannemreddy
    Department of Neurosurgery, Rush University Medical Center, 1725 W Harrison Street, Chicago, IL, USA
    J Neurooncol 115:225-31. 2013
    ..Given that the diagnosis of treatment-resistant TLE secondary to HS can be established after two failed AED trials at optimal doses, shortening the interval between diagnosis and surgery may improve epilepsy outcome...
  32. doi request reprint Can neurobiological pathogenic mechanisms of depression facilitate the development of seizure disorders?
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Rush University, Chicago, IL 60612, USA
    Lancet Neurol 11:1093-102. 2012
    ..The data presented in this Review provide experimental evidence that might begin to explain the bidirectional relation between depressive disorders and epilepsy and that can be regarded as a source for future research...
  33. doi request reprint Are antiepileptic drugs used in the treatment of migraine associated with an increased risk of suicidality?
    Andres M Kanner
    Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Curr Pain Headache Rep 15:164-9. 2011
    ..In this article, we review data to determine whether the AEDs used in the prevention of migraine are associated with an increased risk of suicidality...
  34. doi request reprint Ictal panic and interictal panic attacks: diagnostic and therapeutic principles
    Andres M Kanner
    Department of Neurological Sciences, Rush University Medical Center, Rush Medical College at Rush University, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Neurol Clin 29:163-75, ix. 2011
    ..A careful history is often sufficient to distinguish these events. When necessary, electroencephalography and neuroimaging studies, estimation of prolactin levels can be a helpful tool in establishing an accurate diagnosis...
  35. doi request reprint Postictal affective episodes
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College and Rush University Medical Center, Chicago, IL, USA
    Epilepsy Behav 19:156-8. 2010
    ..Prevention of PDSs and PDEs can be achieved only with seizure freedom, and preliminary uncontrolled data suggest that being on antidepressant medication does not protect patients from experiencing these types of symptoms...
  36. doi request reprint Depression and epilepsy: A bidirectional relation?
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College at Rush University, Rush University Medical Center, Chicago, Illinois 60612, USA
    Epilepsia 52:21-7. 2011
    ....
  37. doi request reprint Depression and epilepsy: a review of multiple facets of their close relation
    Andres M Kanner
    Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Neurol Clin 27:865-80. 2009
    ..The negative impact of depressive disorders in the life of PWE is significant; hence, a prompt recognition should be followed by a treatment designed to yield complete symptom remission...
  38. ncbi request reprint Neuropsychiatric complications of epilepsy
    Andres M Kanner
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Curr Neurol Neurosci Rep 2:365-72. 2002
    ..These include the psychosis of epilepsy, postictal psychotic disorders, alternative psychosis (or forced normalization), and certain forms of interictal depressive disorders...
  39. ncbi request reprint The localizing yield of sphenoidal and anterior temporal electrodes in ictal recordings: a comparison study
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, and Rush Epilepsy Center, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
    Epilepsia 43:1189-96. 2002
    ..To compare the localizing yield of sphenoidal electrodes placed under fluoroscopic guidance (SEs) and anterior temporal electrodes (ATEs) in ictal recordings from a group of patients with seizure disorders of anterior temporal origin...
  40. ncbi request reprint The use of monotherapy in patients with epilepsy: an appraisal of the new antiepileptic drugs
    Andres M Kanner
    Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
    Curr Neurol Neurosci Rep 5:322-8. 2005
    ....
  41. ncbi request reprint Depression and epilepsy: how closely related are they?
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Neurology 58:S27-39. 2002
    ..Contrary to clinicians' fears, most antidepressant drugs are safe in patients with epilepsy...
  42. ncbi request reprint More controversies on the treatment of psychogenic pseudoseizures: an addendum
    Andres M Kanner
    Department of Neurological Sciences, Rush Medical College, Section of Epilepsy and Clinical Neurophysiology and Rush Epilepsy Center, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Epilepsy Behav 4:360-4. 2003
    ..Finally, I discuss the timing of introducing a psychogenic cause during the presentation of the diagnosis to patient and family...
  43. doi request reprint Predicting white matter targets for direct neurostimulation therapy
    Marvin A Rossi
    Department Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Epilepsy Res 91:176-86. 2010
    ..This workflow demonstrates the feasibility of planning white matter-electrode placement with individual specificity to predict propagation of electrical current throughout an epileptic circuit...
  44. ncbi request reprint Efficacy and tolerability of the new antiepileptic drugs, II: Treatment of refractory epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society
    Jacqueline A French
    Neurological Institute, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Epilepsia 45:410-23. 2004
    ....
  45. ncbi request reprint Screening for major depression in epilepsy with common self-report depression inventories
    Jana E Jones
    Department of Neurology, University of Wisconsin Madison, 53792, USA
    Epilepsia 46:731-5. 2005
    ..The purpose of this study was to determine the ability of two common depressive symptom inventories to identify major depression in people with epilepsy...
  46. ncbi request reprint The diagnostic significance of video-EEG monitoring findings on pseudoseizure patients differs between neurologists and psychiatrists
    Cynthia L Harden
    Comprehensive Epilepsy Center, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York, USA
    Epilepsia 44:453-6. 2003
    ..In an attempt to elucidate factors contributing to this poor outcome, we hypothesized that neurologists and psychiatrists differ in their views of the diagnosis and management of psychogenic pseudoseizure patients...
  47. ncbi request reprint Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society
    Jacqueline A French
    Neurological Institute, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Epilepsia 45:401-9. 2004
    ..S. Food and Drug Administration] in the treatment of children and adults with newly diagnosed partial and generalized epilepsies...
  48. ncbi request reprint Clinical assessment of Axis I psychiatric morbidity in chronic epilepsy: a multicenter investigation
    Jana E Jones
    Department of Neurology, University of Wisconsin Madison, 53792 6180, USA
    J Neuropsychiatry Clin Neurosci 17:172-9. 2005
    ..Issues regarding recognition and treatment of psychiatric morbidity in epilepsy are discussed...
  49. ncbi request reprint Mood disorders in the medically ill: scientific review and recommendations
    Dwight L Evans
    School of Medicine, University of Pennsylvania, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Biol Psychiatry 58:175-89. 2005
    ....
  50. ncbi request reprint Epilepsy, suicidal behaviour, and depression: do they share common pathogenic mechanisms?
    Andres M Kanner
    Lancet Neurol 5:107-8. 2006
  51. doi request reprint Evaluation and management of epilepsy today: introductory remarks
    Andres M Kanner
    Semin Neurol 28:273-5. 2008
  52. ncbi request reprint The measurement of ammonia blood levels in patients taking valproic acid: looking for problems where they do not exist?
    Ada V Chicharro
    Departamento de Neurología Hospital Sótero del Río, Santiago, Chile
    Epilepsy Behav 11:361-6. 2007
    ..There was no association between HA and clinical symptoms. Concomitant administration of other antiepileptic drugs (AEDs) was the factor most frequently associated with HA...
  53. ncbi request reprint Rates and risk factors for suicide, suicidal ideation, and suicide attempts in chronic epilepsy
    Jana E Jones
    Department of Neurology, University of Wisconsin Madison, Madison, WI, USA
    Epilepsy Behav 4:S31-8. 2003
    ..Assessing severity of risk helps to determine the appropriate level of intervention. The suicidality module of the Mini-International Neuropsychiatric Interview is a practical tool to help quantify current suicide risk...
  54. ncbi request reprint What should psychiatry residents be taught about neurology?: A survey of psychiatry residency directors
    Linda M Selwa
    University of Michigan Department of Neurology, Ann Arbor, Michigan, USA
    Neurologist 12:268-70. 2006
    ..To improve our ability to teach psychiatry residents during their required 2 months on neurology rotations, we investigated the perceived needs of psychiatry program training directors...
  55. ncbi request reprint Is the neurologist's role over once the diagnosis of psychogenic nonepileptic seizures is made? No!
    Andres M Kanner
    Epilepsy Behav 12:1-2. 2008
  56. ncbi request reprint Consensus statement: the evaluation and treatment of people with epilepsy and affective disorders
    John J Barry
    Department of Psychiatry and Behavioral Sciences, Stanford University Medical Center, Stanford, CA, USA
    Epilepsy Behav 13:S1-29. 2008
    ..Recommendations are based on the general depression literature as well as epilepsy-specific studies. It is hoped that this document will improve the overall detection and subsequent treatment of affective illnesses in PWE...