Research Topics
| A M KannerSummaryAffiliation: Rush University Medical Center Country: USA Publications
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Detail Information
Publications
Can neurobiological pathogenic mechanisms of depression facilitate the development of seizure disorders?Andres M Kanner
Department of Neurological Sciences, Rush Medical College, Rush University, Chicago, IL 60612, USA
Lancet Neurol 11:1093-102. 2012..The data presented in this Review provide experimental evidence that might begin to explain the bidirectional relation between depressive disorders and epilepsy and that can be regarded as a source for future research...- Depressive and anxiety disorders in epilepsy: do they differ in their potential to worsen common antiepileptic drug-related adverse events?Andres M Kanner
Department of Neurological Sciences, Rush Medical College, Chicago, Illinois 60612, USA
Epilepsia 53:1104-8. 2012..To compare the effect of anxiety disorders, major depressive episodes (MDEs), and subsyndromic depressive episodes (SSDEs) on antiepileptic drug (AED)-related adverse events (AEs) in persons with epilepsy (PWE)... - Depression and epilepsy, pain and psychogenic non-epileptic seizures: clinical and therapeutic perspectivesAndres M Kanner
Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
Epilepsy Behav 24:169-81. 2012..Thus, clinicians have had to adopt data from patients with primary depressive disorders. We outline a consensus strategy on the identification and treatment of depressive disorders in adult and pediatric patients with epilepsy... - Depression and epilepsy: epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrenceAndres M Kanner
Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
Epilepsy Behav 24:156-68. 2012..The negative impact of depression on the control of seizure disorders has been documented in various studies. In this manuscript, these data are reviewed and potential mechanisms explaining this phenomenon are proposed... - Are antiepileptic drugs used in the treatment of migraine associated with an increased risk of suicidality?Andres M Kanner
Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
Curr Pain Headache Rep 15:164-9. 2011..In this article, we review data to determine whether the AEDs used in the prevention of migraine are associated with an increased risk of suicidality... 
The use of monotherapy in patients with epilepsy: an appraisal of the new antiepileptic drugsAndres M Kanner
Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
Curr Neurol Neurosci Rep 5:322-8. 2005....- Depression in epilepsy: a complex relation with unexpected consequencesAndres M Kanner
Department of Neurological Sciences and Psychiatry, Rush Medical College, Laboratory of Electroencephalography and Video EEG Telemetry, Rush University Medical Center, Chicago, Illinois 60612, USA
Curr Opin Neurol 21:190-4. 2008..The recent significant increase in research on depressive disorders in epilepsy has led to a greater recognition of its negative impact on multiple aspects of these patients' lives. Thus, a review of this topic could not be timelier... - Epilepsy and mood disordersAndres M Kanner
Department of Neurological Sciences, Rush Medical College, Rush University Medical Center, Chicago, Illinois 60612, USA
Epilepsia 48:20-2. 2007.... - Long-term significance of postictal psychotic episodes I. Are they predictive of bilateral ictal foci?Andres M Kanner
Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
Epilepsy Behav 12:150-3. 2008..The aim of this study was to determine the degree to which postictal psychotic episodes (PIPE) are predictive of bilateral independent ictal foci... - Long-term significance of postictal psychotic episodes II. Are they predictive of interictal psychotic episodes?Andres M Kanner
Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
Epilepsy Behav 12:154-6. 2008..The aim of this study was to determine whether postictal psychotic episodes (PIPE) are predictive of the development of interictal psychotic episodes (IPE)... 
Mood disorder and epilepsy: a neurobiologic perspective of their relationshipAndres M Kanner
Rush Medical College, Rush University Medical Center, Chicago, Illinois 60612, USA
Dialogues Clin Neurosci 10:39-45. 2008..Indeed, patients with a history of mood disorders are twice as likely to develop pharmacoresistant epilepsy as those without such a history. These data are reviewed in this article...- Common errors made in the diagnosis and treatment of epilepsyAndres M Kanner
Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
Semin Neurol 28:364-78. 2008..In addition to a discussion of the reasons for the errors, the article provides practical solutions... - The use of psychotropic drugs in epilepsy: what every neurologist should knowAndres M Kanner
Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
Semin Neurol 28:379-88. 2008..This article provides a practical review of the use of antidepressants, central nervous system stimulants, and antipsychotic drugs in patients with epilepsy... - Psychiatric issues in epilepsy: the complex relation of mood, anxiety disorders, and epilepsyAndres M Kanner
Department of Neurological Sciences, Rush Medical College, 1653 West Congress Parkway, Chicago, IL, USA
Epilepsy Behav 15:83-7. 2009..The significance of such a relation is not only theoretical, but has a marked impact on the response to pharmacological and surgical treatment of seizure disorders... - A lifetime psychiatric history predicts a worse seizure outcome following temporal lobectomyA M Kanner
Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
Neurology 72:793-9. 2009..Purpose: To identify the psychiatric and epilepsy variables predictive of postsurgical seizure outcome after anterotemporal lobectomy (ATL)... - Depression and epilepsy: do glucocorticoids and glutamate explain their relationship?Andres M Kanner
Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
Curr Neurol Neurosci Rep 9:307-12. 2009..The abnormal role of the hypothalamic-pituitary-adrenal axis is one of the common pathogenic mechanisms that explains why patients with depression are at greater risk for developing epilepsy and vice versa... - Depression and epilepsy: a review of multiple facets of their close relationAndres M Kanner
Department of Neurological Sciences, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
Neurol Clin 27:865-80. 2009..The negative impact of depressive disorders in the life of PWE is significant; hence, a prompt recognition should be followed by a treatment designed to yield complete symptom remission... - Ictal panic and interictal panic attacks: diagnostic and therapeutic principlesAndres M Kanner
Department of Neurological Sciences, Rush University Medical Center, Rush Medical College at Rush University, 1653 West Congress Parkway, Chicago, IL 60612, USA
Neurol Clin 29:163-75, ix. 2011..A careful history is often sufficient to distinguish these events. When necessary, electroencephalography and neuroimaging studies, estimation of prolactin levels can be a helpful tool in establishing an accurate diagnosis... - Depression and epilepsy: A bidirectional relation?Andres M Kanner
Department of Neurological Sciences, Rush Medical College at Rush University, Rush University Medical Center, Chicago, Illinois 60612, USA
Epilepsia 52:21-7. 2011.... - Should neurologists be trained to recognize and treat comorbid depression of neurologic disorders? YesAndres M Kanner
Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center and Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL, USA
Epilepsy Behav 6:303-11. 2005.... - A past psychiatric history may be a risk factor for topiramate-related psychiatric and cognitive adverse eventsAndres M Kanner
Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Rush Medical College, 1653 West Congress Parkway, Chicago, IL 60612, USA
Epilepsy Behav 4:548-52. 2003.... - Postictal affective episodesAndres M Kanner
Department of Neurological Sciences, Rush Medical College and Rush University Medical Center, Chicago, IL, USA
Epilepsy Behav 19:156-8. 2010..Prevention of PDSs and PDEs can be achieved only with seizure freedom, and preliminary uncontrolled data suggest that being on antidepressant medication does not protect patients from experiencing these types of symptoms... - Structural MRI changes of the brain in depressionAndres M Kanner
Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
Clin EEG Neurosci 35:46-52. 2004..The purpose of this article is to briefly review the published data on neuroanatomical structural changes associated with major depressive and bipolar disorders... - The localizing yield of sphenoidal and anterior temporal electrodes in ictal recordings: a comparison studyAndres M Kanner
Department of Neurological Sciences, Rush Medical College, and Rush Epilepsy Center, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
Epilepsia 43:1189-96. 2002..To compare the localizing yield of sphenoidal electrodes placed under fluoroscopic guidance (SEs) and anterior temporal electrodes (ATEs) in ictal recordings from a group of patients with seizure disorders of anterior temporal origin... - Neuropsychiatric complications of epilepsyAndres M Kanner
Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA
Curr Neurol Neurosci Rep 2:365-72. 2002..These include the psychosis of epilepsy, postictal psychotic disorders, alternative psychosis (or forced normalization), and certain forms of interictal depressive disorders... - Recognition of the various expressions of anxiety, psychosis, and aggression in epilepsyAndres M Kanner
Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center at Rush University Medical Center, Chicago, Illinois 60612, USA
Epilepsia 45:22-7. 2004..In this article, three case studies are presented to illustrate the importance of distinguishing psychiatric symptoms of anxiety, psychosis, and aggression, with respect to their temporal relation with seizure occurrence... - When did neurologists and psychiatrists stop talking to each other?Andres M Kanner
Department of Neurological Sciences, Rush Medical College, Chicago, IL, USA
Epilepsy Behav 4:597-601. 2003..The purpose of this paper is to highlight this bizarre phenomenon and to identify some of the reasons behind it... - The "forgotten" cross-tolerance between phenobarbital and primidone: it can prevent acute primidone-related toxicityA M Kanner
Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center and Rush Presbyterian Saint Luke s Medical Center, Chicago, Illinois 60612, USA
Epilepsia 41:1310-4. 2000..We report on the effect that pretreating patients with phenobarbital has on averting adverse events when primidone is introduced... - The complex epilepsy patient: intricacies of assessment and treatmentAndres M Kanner
Laboratory of Electroencephalography and Video EEG Telemetry, Department of Neurological Science, Rush Presbyterian St Luke s Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, U S A
Epilepsia 44:3-8. 2003..Clearly, treating epilepsy is not only about controlling seizures... - Adding valproate to lamotrigine: a study of their pharmacokinetic interactionA M Kanner
Section of Epilepsy and Clinical Neurophysiology, Department of Neurological Sciences, Rush Medical College, and Rush Epilepsy Center, Rush Presbyterian Saint Luke s Medical Center, Chicago, IL 60612, USA
Neurology 55:588-91. 2000..Correlations between LTG clearance and the dose and Css of VPA and comparisons of LTG clearance during low and high doses of VPA demonstrated that the degree of inhibition of LTG clearance is independent of the dose and Css of VPA... - The impact of mood disorders in neurological diseases: should neurologists be concerned?Andres M Kanner
Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
Epilepsy Behav 4:S3-13. 2003.... - Management of newly diagnosed epilepsy: a practical guide to monotherapyMichael A Stein
Department of Neurological Sciences, Rush University Medical Centre, Chicago, Illinois 60612, USA
Drugs 69:199-222. 2009..Finally, this information is conveniently summarized in a set of tables and illustrated by way of case scenarios... - Diagnosis and management of depression and psychosis in children and adolescents with epilepsyAndres M Kanner
Department of Neurological Sciences, Rush Medical College, Chicago, IL 60612, USA
J Child Neurol 19:S65-72. 2004..Although both antidepressants and antipsychotic drugs have the potential to lower the seizure threshold and increase seizures, careful drug selection, dosing, and slow titration can minimize this risk, allowing treatment to proceed... - Depression in epilepsy: prevalence, clinical semiology, pathogenic mechanisms, and treatmentAndres M Kanner
Department of Neurological Sciences, Rush Medical College, Chicago, Illinois 60612, USA
Biol Psychiatry 54:388-98. 2003..Despite its relatively high prevalence, depression remains unrecognized and untreated, and unfortunately its treatment is based on empirical and uncontrolled data... - More controversies on the treatment of psychogenic pseudoseizures: an addendumAndres M Kanner
Department of Neurological Sciences, Rush Medical College, Section of Epilepsy and Clinical Neurophysiology and Rush Epilepsy Center, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
Epilepsy Behav 4:360-4. 2003..Finally, I discuss the timing of introducing a psychogenic cause during the presentation of the diagnosis to patient and family... - Anxiety disorders, subsyndromic depressive episodes, and major depressive episodes: do they differ on their impact on the quality of life of patients with epilepsy?Andres M Kanner
Department of Neurological Sciences, Rush Medical College, Chicago, Illinois 60612, USA
Epilepsia 51:1152-8. 2010.... - Depression and epilepsy: how closely related are they?Andres M Kanner
Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
Neurology 58:S27-39. 2002..Contrary to clinicians' fears, most antidepressant drugs are safe in patients with epilepsy... - Depression in epilepsy: a frequently neglected multifaceted disorderAndres M Kanner
Department of Neurological Sciences, Rush Medical College, Chicago, IL, USA
Epilepsy Behav 4:11-9. 2003.... - Pharmacodynamic and pharmacokinetic interactions of psychotropic drugs with antiepileptic drugsAndres M Kanner
Rush University Medical Center, Chicago, Illinois, USA
Int Rev Neurobiol 83:397-416. 2008..This chapter provides a practical review on the use of psychotropic drugs for the treatment of these psychiatric co-morbidities in patients with epilepsy... - Depression and the risk of neurological disordersAndres M Kanner
Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush University Medical Center, Chicago, IL 60612, USA
Lancet 366:1147-8. 2005 - Is major depression a neurologic disorder with psychiatric symptoms?Andres M Kanner
Department of Neurological Sciences, Rush Medical College, Rush Epilepsy Center, Rush University Medical Center, Chicago, IL, USA
Epilepsy Behav 5:636-44. 2004..This article reviews these data and provides evidence that major depressive and bipolar disorders may in fact be neurologic disorders with psychiatric symptoms... - Prevalence and clinical characteristics of postictal psychiatric symptoms in partial epilepsyAndres M Kanner
Division of Epilepsy, Department of Neurological Sciences, Rush Medical College, Rush University Medical Center, Chicago, IL, USA
Neurology 62:708-13. 2004.... - The diagnostic significance of video-EEG monitoring findings on pseudoseizure patients differs between neurologists and psychiatristsCynthia L Harden
Comprehensive Epilepsy Center, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York, USA
Epilepsia 44:453-6. 2003..In an attempt to elucidate factors contributing to this poor outcome, we hypothesized that neurologists and psychiatrists differ in their views of the diagnosis and management of psychogenic pseudoseizure patients... - Epilepsy, suicidal behaviour, and depression: do they share common pathogenic mechanisms?Andres M Kanner
Lancet Neurol 5:107-8. 2006 - Mood disorders in the medically ill: scientific review and recommendationsDwight L Evans
School of Medicine, University of Pennsylvania, 423 Guardian Drive, Philadelphia, PA 19104, USA
Biol Psychiatry 58:175-89. 2005.... - Clinical assessment of Axis I psychiatric morbidity in chronic epilepsy: a multicenter investigationJana E Jones
Department of Neurology, University of Wisconsin Madison, 53792 6180, USA
J Neuropsychiatry Clin Neurosci 17:172-9. 2005..Issues regarding recognition and treatment of psychiatric morbidity in epilepsy are discussed... - Screening for major depression in epilepsy with common self-report depression inventoriesJana E Jones
Department of Neurology, University of Wisconsin Madison, 53792, USA
Epilepsia 46:731-5. 2005..The purpose of this study was to determine the ability of two common depressive symptom inventories to identify major depression in people with epilepsy... - Efficacy and tolerability of the new antiepileptic drugs, II: Treatment of refractory epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy SocietyJacqueline A French
Neurological Institute, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Epilepsia 45:410-23. 2004.... - Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy SocietyJacqueline A French
Neurological Institute, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Epilepsia 45:401-9. 2004..S. Food and Drug Administration] in the treatment of children and adults with newly diagnosed partial and generalized epilepsies... - Rapid detection of major depression in epilepsy: a multicentre studyFrank G Gilliam
Department of Neurology, The Neurological Institute, Columbia University, New York, USA
Lancet Neurol 5:399-405. 2006..Depression is a common comorbid disorder in epilepsy but is not routinely assessed in neurology clinics. We aimed to create a rapid yet accurate screening instrument for major depression in people with epilepsy... - Evaluation and management of epilepsy today: introductory remarksAndres M Kanner
Semin Neurol 28:273-5. 2008 - What should psychiatry residents be taught about neurology?: A survey of psychiatry residency directorsLinda M Selwa
University of Michigan Department of Neurology, Ann Arbor, Michigan, USA
Neurologist 12:268-70. 2006..To improve our ability to teach psychiatry residents during their required 2 months on neurology rotations, we investigated the perceived needs of psychiatry program training directors... - The measurement of ammonia blood levels in patients taking valproic acid: looking for problems where they do not exist?Ada V Chicharro
Departamento de Neurología Hospital Sótero del Río, Santiago, Chile
Epilepsy Behav 11:361-6. 2007..There was no association between HA and clinical symptoms. Concomitant administration of other antiepileptic drugs (AEDs) was the factor most frequently associated with HA... - Is the neurologist's role over once the diagnosis of psychogenic nonepileptic seizures is made? No!Andres M Kanner
Epilepsy Behav 12:1-2. 2008 - Rates and risk factors for suicide, suicidal ideation, and suicide attempts in chronic epilepsyJana E Jones
Department of Neurology, University of Wisconsin Madison, Madison, WI, USA
Epilepsy Behav 4:S31-8. 2003..Assessing severity of risk helps to determine the appropriate level of intervention. The suicidality module of the Mini-International Neuropsychiatric Interview is a practical tool to help quantify current suicide risk... - Consensus statement: the evaluation and treatment of people with epilepsy and affective disordersJohn J Barry
Department of Psychiatry and Behavioral Sciences, Stanford University Medical Center, Stanford, CA, USA
Epilepsy Behav 13:S1-29. 2008..Recommendations are based on the general depression literature as well as epilepsy-specific studies. It is hoped that this document will improve the overall detection and subsequent treatment of affective illnesses in PWE...