C G Goetz

Summary

Affiliation: Rush University Medical Center
Country: USA

Publications

  1. ncbi request reprint Rating scale for psychogenic movement disorders: scale development and clinimetric testing
    Vanessa K Hinson
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina, USA
    Mov Disord 20:1592-7. 2005
  2. pmc Treating melancholia at home: theoretical wisdom and grim reality in the career of E.C. Seguin
    Christopher G Goetz
    Rush University Medical Center, Chicago, IL, USA
    Neurology 80:1710-4. 2013
  3. doi request reprint Which dyskinesia scale best detects treatment response?
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 28:341-6. 2013
  4. pmc The history of Parkinson's disease: early clinical descriptions and neurological therapies
    Christopher G Goetz
    Department of Neurological Sciences and Department of Pharmacology, Rush University Medical Center, Chicago, Illinois 60612, USA
    Cold Spring Harb Perspect Med 1:a008862. 2011
  5. pmc Motor function in Parkinson's disease and supranuclear palsy: simultaneous factor analysis of a clinical scale in several populations
    Pieter M Kroonenberg
    Department of Education and Child Study, Wassenaarseweg 52, Leiden University, Leiden, The Netherlands
    BMC Med Res Methodol 6:26. 2006
  6. ncbi request reprint Charcot in contemporary literature
    Christopher G Goetz
    Neurological Sciences and Pharmacology, Rush University Medical Center, IL 60612, USA
    J Hist Neurosci 15:22-30. 2006
  7. ncbi request reprint Does seasonal variation affect hallucinations in PD? A longitudinal study
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 21:863-5. 2006
  8. ncbi request reprint The malignant course of "benign hallucinations" in Parkinson disease
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, 1725 W Harrison Street, Chicago, IL 60612, USA
    Arch Neurol 63:713-6. 2006
  9. ncbi request reprint Evaluating Parkinson's disease patients at home: utility of self-videotaping for objective motor, dyskinesia, and ON-OFF assessments
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 23:1479-82. 2008
  10. ncbi request reprint Early cinematographic studies of generalized dystonia
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 21:1561-5. 2006

Research Grants

  1. Multiple Factors Affecting Placebo Response in PD
    Christopher Goetz; Fiscal Year: 2004

Collaborators

Detail Information

Publications110 found, 100 shown here

  1. ncbi request reprint Rating scale for psychogenic movement disorders: scale development and clinimetric testing
    Vanessa K Hinson
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina, USA
    Mov Disord 20:1592-7. 2005
    ..The PMD scale adequately captures the complex movements of PMDs and can be used to assess PMDs and test the efficacy of intervention strategies...
  2. pmc Treating melancholia at home: theoretical wisdom and grim reality in the career of E.C. Seguin
    Christopher G Goetz
    Rush University Medical Center, Chicago, IL, USA
    Neurology 80:1710-4. 2013
    ..The grim dichotomy between the confidently written paper and the reality of the treatment failure is a neurologic lesson in humility regarding diseases and their unpredictable outcomes...
  3. doi request reprint Which dyskinesia scale best detects treatment response?
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 28:341-6. 2013
    ....
  4. pmc The history of Parkinson's disease: early clinical descriptions and neurological therapies
    Christopher G Goetz
    Department of Neurological Sciences and Department of Pharmacology, Rush University Medical Center, Chicago, Illinois 60612, USA
    Cold Spring Harb Perspect Med 1:a008862. 2011
    ....
  5. pmc Motor function in Parkinson's disease and supranuclear palsy: simultaneous factor analysis of a clinical scale in several populations
    Pieter M Kroonenberg
    Department of Education and Child Study, Wassenaarseweg 52, Leiden University, Leiden, The Netherlands
    BMC Med Res Methodol 6:26. 2006
    ....
  6. ncbi request reprint Charcot in contemporary literature
    Christopher G Goetz
    Neurological Sciences and Pharmacology, Rush University Medical Center, IL 60612, USA
    J Hist Neurosci 15:22-30. 2006
    ..Neurologists should not look to these works as replacements for more seriously composed historical studies, but as enrichments anchored in the imaginative possibilities of Charcot and his fin de siècle era...
  7. ncbi request reprint Does seasonal variation affect hallucinations in PD? A longitudinal study
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 21:863-5. 2006
    ..Because we found no evidence of seasonal variations, we cannot recommend phototherapy or other strategies affecting chronobiological systems as research priorities to treat PD hallucinations. (c) 2006 Movement Disorder Society...
  8. ncbi request reprint The malignant course of "benign hallucinations" in Parkinson disease
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, 1725 W Harrison Street, Chicago, IL 60612, USA
    Arch Neurol 63:713-6. 2006
    ..To monitor progression of "benign hallucinations" in Parkinson disease (PD)...
  9. ncbi request reprint Evaluating Parkinson's disease patients at home: utility of self-videotaping for objective motor, dyskinesia, and ON-OFF assessments
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 23:1479-82. 2008
    ..In this group of patients with no or mild fluctuations, in spite of pretrial training, patients were inaccurate in separating ON vs. OFF status...
  10. ncbi request reprint Early cinematographic studies of generalized dystonia
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 21:1561-5. 2006
    ..The films demonstrate the variety of dystonic movements appreciated during this period, consider psychogenic, postencephalitic, and hereditary forms, and refer to the treatment of dystonia by surgery and plaster casts...
  11. ncbi request reprint Sarizotan as a treatment for dyskinesias in Parkinson's disease: a double-blind placebo-controlled trial
    Christopher G Goetz
    Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 22:179-86. 2007
    ..Sarizotan 2 mg/day is a safe agent in PD patients with dyskinesia. To test its role in abating dyskinesia, future studies should focus on this dose and will use the composite score of UPDRS Items 32+33 as the primary outcome...
  12. ncbi request reprint Age-related influences on the clinical characteristics of new-onset hallucinations in Parkinson's disease patients
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 21:267-70. 2006
    ..Age-related disinhibition may facilitate wider cortical activation in PD and potentiate aberrant signaling that invokes other types of hallucinations besides the classic visual forms...
  13. ncbi request reprint Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004
    Christopher G Goetz
    Department of Neurological Sciences, Department of Pharmacology, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 20:523-39. 2005
    ..We consider a 3-year period a reasonable time frame for published updates and are working to establish a Web-based mechanism to update the report in an ongoing manner...
  14. ncbi request reprint Safety of rasagiline in elderly patients with Parkinson disease
    C G Goetz
    Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 66:1427-9. 2006
    ..This absence of an age-rasagiline interaction suggests that rasagiline does not require special safety precautions for elderly subjects with Parkinson disease...
  15. ncbi request reprint Hallucinations and sleep disorders in PD: six-year prospective longitudinal study
    Christopher G Goetz
    Department of Neurological Sciences, Rush Medical College, Rush University, Chicago, IL, USA
    Neurology 64:81-6. 2005
    ..To prospectively assess the relationship of hallucinations to sleep disorders in patients with Parkinson disease (PD) over 6 years...
  16. ncbi request reprint Movement disorders: understanding clinical trials
    Christopher G Goetz
    Rush University Medical Center, Chicago IL 60612, USA
    Lancet Neurol 4:5-6. 2005
  17. ncbi request reprint Assuring interrater reliability for the UPDRS motor section: utility of the UPDRS teaching tape
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 19:1453-6. 2004
    ..Raters have the greatest difficulty with the mildest impairment, making training especially important to studies of early PD...
  18. ncbi request reprint Movement Disorder Society Task Force report on the Hoehn and Yahr staging scale: status and recommendations
    Christopher G Goetz
    Rush University Medical Center, 1725 W Harrison Street, Chicago, IL 60612, USA
    Mov Disord 19:1020-8. 2004
    ..5 increments, this adaptation warrants clinimetric testing. Without such testing, however, the original five-point scales should be maintained...
  19. ncbi request reprint Medical-legal issues in Charcot's neurologic career
    Christopher G Goetz
    Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 62:1827-33. 2004
    ..Trace the medical-legal involvement of the 19th century clinical neurologist Jean-Martin Charcot...
  20. ncbi request reprint Standardized training tools for the UPDRS activities of daily living scale: newly available teaching program
    Christopher G Goetz
    Department of Neurological Sciences, Rush University, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
    Mov Disord 18:1455-8. 2003
    ..The written materials and videotape belong to the Movement Disorder Society and are available by contacting the MDS central office...
  21. ncbi request reprint Impact of placebo assignment in clinical trials of Parkinson's disease
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 18:1146-9. 2003
    ..Although most wish they received the active compound being tested, the overall view of participation in placebo-controlled trials is viewed very positively by PD patients...
  22. ncbi request reprint Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Process, format, and clinimetric testing plan
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 22:41-7. 2007
    ....
  23. ncbi request reprint J.-M. Charcot and simulated neurologic disease: attitudes and diagnostic strategies
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 69:103-9. 2007
    ..Neurologists have long wrestled with the diagnosis of elaborated or feigned disease. Studies have not focused on early techniques utilized to diagnose malingering...
  24. doi request reprint Temporal stability of the Unified Dyskinesia Rating Scale
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA
    Mov Disord 26:2556-9. 2011
    ..The UDysRS has strong internal consistency and a reliable factor structure, but the important issue of temporal stability has not been established...
  25. doi request reprint Visual plus nonvisual hallucinations in Parkinson's disease: development and evolution over 10 years
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA
    Mov Disord 26:2196-200. 2011
    ..To capture the breadth and severity of hallucinations in chronically hallucinating patients with Parkinson's disease, screening inventories and practice-based interviews must include questions on both visual and nonvisual components...
  26. doi request reprint The movement disorder society and movement disorders: a modern history
    Christopher G Goetz
    Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 26:939-46. 2011
    ..Movement Disorders has a continuingly growing subscribership and rising impact factor...
  27. pmc Hallucinations and sleep disorders in PD: ten-year prospective longitudinal study
    Christopher G Goetz
    Movement Disorders Section, Department of Neurological Sciences, Rush University Medical Center, Suite 1106, Chicago, IL 60612, USA
    Neurology 75:1773-9. 2010
    ..To assess prospectively progression and relationship of hallucinations and sleep disorders over a 10-year longitudinal study of patients with Parkinson disease (PD)...
  28. ncbi request reprint Teaching program for the Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale: (MDS-UPDRS)
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 25:1190-4. 2010
    ..This training program is in English, but as non-English official translations of the MDS-UPDRS are developed, the program can be potentially modified into different languages...
  29. pmc Shaking up the Salpetriere: Jean-Martin Charcot and mercury-induced tremor
    Christopher G Goetz
    Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 74:1739-42. 2010
    ..To analyze Jean-Martin Charcot's studies of mercury-induced tremor...
  30. doi request reprint New developments in depression, anxiety, compulsiveness, and hallucinations in Parkinson's disease
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA
    Mov Disord 25:S104-9. 2010
    ..New treatments are being developed, but there have been very few large-scale randomized clinical trials to test the relative roles of new or available agents for abating these problematic behaviors...
  31. doi request reprint Scales to evaluate psychosis in Parkinson's disease
    Christopher G Goetz
    Rush University Medical Center, Chicago, IL 60612, USA
    Parkinsonism Relat Disord 15:S38-41. 2009
    ..The Task Force officially recommended the development of a new scale to assess hallucinations and psychosis in Parkinson's disease. This effort is now ongoing with official endorsement by the Movement Disorder Society...
  32. doi request reprint Jean-Martin Charcot and his vibratory chair for Parkinson disease
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA
    Neurology 73:475-8. 2009
    ..Although after Charcot's death vibratory therapy was not widely pursued, vibratory appliances are reemerging in 21st century medicine and can be retested using adaptations of Charcot's neurologic protocols...
  33. ncbi request reprint Teaching program for the Unified Dyskinesia Rating Scale
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 24:1296-8. 2009
    ..Large-scale multicenter randomized clinical trials of dyskinesia treatment are strengthened by a uniform standard of scale application...
  34. pmc Testing objective measures of motor impairment in early Parkinson's disease: Feasibility study of an at-home testing device
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA
    Mov Disord 24:551-6. 2009
    ....
  35. doi request reprint Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 23:2129-70. 2008
    ..90 for each part), which support the use of sum scores for each part in preference to a total score of all parts. The combined clinimetric results of this study support the validity of the MDS-UPDRS for rating PD...
  36. doi request reprint The Unified Dyskinesia Rating Scale: presentation and clinimetric profile
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA
    Mov Disord 23:2398-403. 2008
    ..The UDysRS is a clinimetrically sound rating scale for dyskinesia in PD, demonstrating acceptable levels of internal consistency and inter- and intra-rater reliability. Testing scale responsivity to treatment interventions is planned...
  37. doi request reprint Antipsychotic medication treatment for mild hallucinations in Parkinson's disease: Positive impact on long-term worsening
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 23:1541-5. 2008
    ....
  38. ncbi request reprint Placebo response in Parkinson's disease: comparisons among 11 trials covering medical and surgical interventions
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 23:690-9. 2008
    ..Recognition of factors that impact placebo response rates should be incorporated into individual study designs for PD clinical trials...
  39. pmc Placebo influences on dyskinesia in Parkinson's disease
    Christopher G Goetz
    Rush University Medical Center, Chicago, Illinois, USA
    Mov Disord 23:700-7. 2008
    ..The magnitude and variance of placebo-related changes and the factors that influence them can be helpful in the design of future clinical trials of antidyskinetic agents...
  40. ncbi request reprint Pierre Marie: gifted intellect, poor timing and unchecked emotionality
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Rush Presbyterian St Luke s Medical Centre, 1725 W Harrison Street, Suite 755, Chicago, IL 60612, USA
    J Hist Neurosci 12:154-66. 2003
    ..In the context of his time, these elements prompted Marie to enter into controversies and medico-political battles that advanced neurological knowledge, but likely disadvantaged him in his career successes...
  41. ncbi request reprint Jean-Martin Charcot and the aging brain
    Christopher G Goetz
    Department of Neurological Sciences and Pharmacology, Rush University Rush Presbyterian St Luke s Medical Center, 1725 W Harrison St, Chicago, IL 60612, USA
    Arch Neurol 59:1821-4. 2002
  42. ncbi request reprint The prefaces by Charcot: leitmotifs of an international career
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Neurology 60:1333-40. 2003
    ....
  43. doi request reprint Chapter 15: Jean-Martin Charcot and the anatomo-clinical method of neurology
    Christopher G Goetz
    Department of Neurological Sciences and Pharmacology, Rush University Medical Center, Chicago, IL 60612, USA
    Handb Clin Neurol 95:203-12. 2010
    ..In the context of Charcot's extensive discoveries and lasting contributions, the anatomo-clinical method remains the anchor of modern neurological diagnosis and is Charcot's most important contribution to clinical neurology...
  44. ncbi request reprint Progression of gait, speech and swallowing deficits in progressive supranuclear palsy
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Rush Presbyterian St Luke s Medical Center, Chicago, IL, USA
    Neurology 60:917-22. 2003
    ..To identify outcome measures for clinical trials in progressive supranuclear palsy (PSP), the authors determined the time to key motor impairments in a well-defined patient cohort...
  45. ncbi request reprint Poor Beard!! Charcot's internationalization of neurasthenia, the "American disease"
    C G Goetz
    Rush University Rush Presbyterian St Luke s Medical Center, Chicago, IL, USA
    Neurology 57:510-4. 2001
    ..To analyze the role of the seminal 19th-century neurologist, Jean-Martin Charcot, in the internationalization of neurasthenia, previously known as "the American disease."..
  46. ncbi request reprint Battle of the titans: Charcot and Brown-Séquard on cerebral localization
    C G Goetz
    Rush University Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Neurology 54:1840-7. 2000
    ....
  47. ncbi request reprint The Brown-Séquard and S. Weir Mitchell letters
    C G Goetz
    Rush Medical College Rush Presbyterian St Luke s Medical Center, Chicago, IL, USA
    Neurology 57:2100-4. 2001
    ....
  48. ncbi request reprint Amyotrophic lateral sclerosis: early contributions of Jean-Martin Charcot
    C G Goetz
    Department of Neurological Sciences, Rush University Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
    Muscle Nerve 23:336-43. 2000
    ..Because of Charcot's fundamental contributions, the eponym "Charcot's disease" has been used internationally in association with amyotrophic lateral sclerosis...
  49. ncbi request reprint [Progressive supranuclear palsy]
    C G Goetz
    Rush University, Presbyterian St Luke s Medical Center, 1725, West Harrison street, Suite 755, Chicago, IL 60612, USA
    Rev Neurol (Paris) 159:3S25-9. 2003
    ..The Kaplan-Meier curves show that the mean duration of the disease before development of one of these signs is 50 months. Research on protocols designed to stop disease progression should be centered on this period...
  50. ncbi request reprint Placebo-associated improvements in motor function: comparison of subjective and objective sections of the UPDRS in early Parkinson's disease
    Christopher G Goetz
    Department of Neurological Sciences Rush University, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 17:283-8. 2002
    ....
  51. ncbi request reprint Prospective longitudinal assessment of hallucinations in Parkinson's disease
    C G Goetz
    Department of Neurological Sciences, Rush University, Chicago, IL, USA
    Neurology 57:2078-82. 2001
    ..The consistent association of hallucinations with combined levodopa/agonist therapy suggests that these drugs may play a role in the pathophysiology of hallucinations...
  52. ncbi request reprint Acute orthostatic hypotension when starting dopamine agonists in Parkinson's disease
    K Kujawa
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Chicago, IL, USA
    Arch Neurol 57:1461-3. 2000
    ..To study the frequency and severity of acute orthostatic hypotension (OH) in patients with Parkinson's disease who are starting dopamine agonist therapy...
  53. ncbi request reprint Early morning off-medication dyskinesias, dystonia, and choreic subtypes
    E Cubo
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Chicago, IL, USA
    Arch Neurol 58:1379-82. 2001
    ..Early morning off-medication choreic dyskinesias have been recently reported after fetal dopaminergic cell transplantations in patients with advanced PD...
  54. ncbi request reprint Delayed recognition memory in Parkinson's disease: a role for working memory?
    G T Stebbins
    Department of Neurological Sciences, Rush Medical College, Chicago, IL 60612, USA
    Neuropsychologia 37:503-10. 1999
    ..These results suggest that the same cognitive processes which support performance on tests of recall and working memory also support performance on tests of delayed recognition...
  55. ncbi request reprint Impaired frontostriatal cognitive functioning following posteroventral pallidotomy in advanced Parkinson's disease
    G T Stebbins
    Department of Neurological Sciences, Rush Medical College, Chicago, IL 60612, USA
    Brain Cogn 42:348-63. 2000
    ..These results suggest that the posteroventral pallidotomy selectively impairs performance on tests of frontostriatal cognitive abilities...
  56. ncbi request reprint Effects of central dopaminergic stimulation by apomorphine on speech in Parkinson's disease
    K Kompoliti
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Rush University, Chicago, IL, USA
    Neurology 54:458-62. 2000
    ..To determine the effect of central dopaminergic stimulation with apomorphine on speech in PD...
  57. ncbi request reprint Movement disorders in Kuru
    K Kompoliti
    Rush Presbyterian St Luke s Medical Center, Rush University, Chicago, Illinois, USA
    Mov Disord 14:800-4. 1999
    ..To describe the gamut of movement disorders (MD) seen during the clinical course of kuru...
  58. ncbi request reprint Objective changes in motor function during placebo treatment in PD
    C G Goetz
    Department of Neurological Sciences, Rush University, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Neurology 54:710-4. 2000
    ..To examine the frequency, temporal development, and stability of objectively derived motor changes during placebo treatment in PD and to define the clinical domains and demographic groups most affected...
  59. ncbi request reprint Altered cortical visual processing in PD with hallucinations: an fMRI study
    G T Stebbins
    Department of Neurological Sciences, Rush University Medical Center, 1725 West Harrison Street, Suite 309, Chicago, IL 60612, USA
    Neurology 63:1409-16. 2004
    ..To compare fMRI activation during two visual stimulation paradigms in Parkinson disease (PD) subjects with chronic visual hallucinations vs PD patients who had never hallucinated...
  60. ncbi request reprint Menstrual-related changes in motoric function in women with Parkinson's disease
    K Kompoliti
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Rush University, Chicago, IL, USA
    Neurology 55:1572-5. 2000
    ..Although PD severity fluctuated during the study period, there was no significant correlation between the objective or subjective measures of parkinsonism and estrogen and progesterone levels...
  61. ncbi request reprint Gender and pramipexole effects on levodopa pharmacokinetics and pharmacodynamics
    K Kompoliti
    Department of Neurological Science, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Neurology 58:1418-22. 2002
    ..5 mg/d and 4.5 mg/d of PPX or placebo. Compared to men, women had greater LD bioavailability. PPX did not alter LD bioavailability, and PPX pharmacokinetics were equivalent in men and women...
  62. ncbi request reprint Home alone: methods to maximize tic expression for objective videotape assessments in Gilles de la Tourette syndrome
    C G Goetz
    Department of Neurological Sciences, Rush University, Rush Presbyterian St. Luke's Medical Center, Chicago, Illinois, USA
    Mov Disord 16:693-7. 2001
    ..Because at-home videotapes consistently yield higher tic expressions than in-office films and capture tics that are not appreciated by patients, this methodology is well-suited for enhanced retrieval of objective data on tic expression...
  63. ncbi request reprint Clinical presentation and pharmacological therapy in corticobasal degeneration
    K Kompoliti
    Rush Presbyterian St Luke s Medical Center, Chicago, Ill 60612, USA
    Arch Neurol 55:957-61. 1998
    ..To date, to our knowledge, there is no systematic presentation of treatment outcome in large series of patients clinically diagnosed as having corticobasal degeneration...
  64. doi request reprint Effects of dopaminergic medications on psychosis and motor function in dementia with Lewy bodies
    Jennifer G Goldman
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 23:2248-50. 2008
    ..Our results suggest that dopaminergic medications have limited benefit in DLB because of the low likelihood of motor improvement and the risk of psychosis exacerbation...
  65. ncbi request reprint The election of Sarah McNutt as the first woman member of the American Neurological Association
    Stacy S Horn
    Department of Neurological Sciences, Rush University, Chicago, IL 60612, USA
    Neurology 59:113-7. 2002
    ..Her historic election acknowledged her accomplishments and highlighted the proactive role of the early ANA in forging new medical policies in the United States...
  66. ncbi request reprint Neuropathic features in fragile X premutation carriers
    Elizabeth Berry-Kravis
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA
    Am J Med Genet A 143:19-26. 2007
    ..These data suggest that neuropathic signs are associated with the fragile X premutation, presumably occurring through the same mechanism proposed for CNS disease, namely, toxicity from expanded-CGG-repeat FMR1 mRNA...
  67. ncbi request reprint Association between antipsychotics and body mass index when treating patients with tics
    Katie Kompoliti
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illionois 60612, USA
    J Child Adolesc Psychopharmacol 20:277-81. 2010
    ..The objective of this study is to investigate the relationship between antipsychotic use and weight in tic patients and compare the effects of SGAs to first-generation (typical) antipsychotics (FGAs)...
  68. doi request reprint Charcot and Pasteur: intersecting orbits in fin de siècle French medicine
    Christopher G Goetz
    Rush University Medical Center, Chicago, IL 60612, USA
    J Hist Neurosci 18:378-86. 2009
    ..With different primary interests and different etiological views, side by side, they exemplified two models of French medicine at the close of the nineteenth century: medical scientist and scientific physician...
  69. doi request reprint Determinants of quality of life in children with Gilles de la Tourette syndrome
    Bryan A Bernard
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 24:1070-3. 2009
    ..ADHD with predominantly inattentive symptoms, rather than hyperactivity symptoms, was associated with lower QOL. To improve QOL, clinicians must consider treatments of co-morbidities among tic patients...
  70. ncbi request reprint Fragile X-associated tremor/ataxia syndrome in sisters related to X-inactivation
    Elizabeth Berry-Kravis
    Department of Pediatrics, Rush University Medical Center, 1275 West Harrison Street, Suite 718, Chicago, IL 60612, USA
    Ann Neurol 57:144-7. 2005
    ....
  71. ncbi request reprint History of the extensor plantar response: Babinski and Chaddock signs
    Christopher G Goetz
    Rush Medical College, Chicago, Illinois, USA
    Semin Neurol 22:391-8. 2002
    ....
  72. ncbi request reprint Tremor and ataxia in fragile X premutation carriers: blinded videotape study
    Elizabeth Berry-Kravis
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Ann Neurol 53:616-23. 2003
    ..Given the relatively high population frequency of the FMR1 premutation, this mutation may be a significant cause of late-onset "idiopathic" progressive tremor...
  73. ncbi request reprint Gilles de la Tourette syndrome: patient's knowledge and concern of adverse effects
    Katie Kompoliti
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 21:248-52. 2006
    ..Overall, patient awareness of NL side effects is insufficient, and although past exposure to NLs enhances knowledge, it decreases concern...
  74. ncbi request reprint Genetic polymorphisms in Parkinson disease subjects with and without hallucinations: an analysis of the cholecystokinin system
    Jennifer G Goldman
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Chicago, Ill 60612, USA
    Arch Neurol 61:1280-4. 2004
    ..Because CCK gene polymorphisms vary across ethnic groups, the presence of similar associations in white PD subjects merits investigation...
  75. ncbi request reprint Ballistic-choreic movements as the presenting feature of renal cancer
    K A Kujawa
    Department of Neurology Sciences, Rush Presbyterian St Luke s Medical Center, Chicago, IL, USA
    Arch Neurol 58:1133-5. 2001
    ..To our knowledge, severe, rapidly progressive, and drug-resistant ballistic-choreic movements have not been previously described as the presenting feature of renal cell carcinoma...
  76. ncbi request reprint Pharmacological therapy in progressive supranuclear palsy
    K Kompoliti
    Rush Presbyterian St Luke s Medical Center, Chicago, Ill 60612, USA
    Arch Neurol 55:1099-102. 1998
    ..To our knowledge, previous reports on drug treatment in progressive supranuclear palsy have not evaluated autopsy-confirmed cases...
  77. ncbi request reprint Estrogen supplementation in the posthypoxic myoclonus rat model
    K Kompoliti
    Department of Neurological Sciences, Rush University, Chicago, Illinois 60612, USA
    Clin Neuropharmacol 24:58-61. 2001
    ..Estrogen enhances and prolongs posthypoxic myoclonus, suggesting that female gender and estrogen status may play a pivotal role as a risk factor for human posthypoxic myoclonus...
  78. ncbi request reprint Charcot and the myth of misogyny
    C G Goetz
    Rush University Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Neurology 52:1678-86. 1999
    ..To evaluate Jean-Martin Charcot's attitudes toward women and evaluate contemporary and modern accusations of misogyny...
  79. doi request reprint Parkinson's disease dementia: definitions, guidelines, and research perspectives in diagnosis
    Christopher G Goetz
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA
    Ann Neurol 64:S81-92. 2008
    ..The inclusion criteria can be applied internationally and in multicenter research on treatment interventions, clinicopathological correlations, and studies of cognitive and other nonmotor elements of PD...
  80. ncbi request reprint Genetic variation analysis in parkinson disease patients with and without hallucinations: case-control study
    C G Goetz
    Department of Neurological Sciences, Rush University Rush Presbyterian St Luke s Medical Center, 1725 W Harrison St, Chicago, IL 60612, USA
    Arch Neurol 58:209-13. 2001
    ..Another study linked the apolipoprotein E4 (APOE4) allele to hallucinations in PD...
  81. ncbi request reprint Treatment of advanced Parkinson's disease: an evidence-based analysis
    Christopher G Goetz
    Department of Neurological Sciences, Department of Pharmacology, Rush University Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
    Adv Neurol 91:213-28. 2003
  82. doi request reprint Comparison of tic characteristics between children and adults
    Esther Cubo
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA
    Mov Disord 23:2407-11. 2008
    ..004) when compared with adults. Tic phenomenology and severity were similar between children and adults, but pharmacological tic management was different, perhaps reflecting a practice trend to avoid medications in children...
  83. ncbi request reprint Treatment of tremor and dystonia
    C G Goetz
    Department of Neurological Sciences, Rush University-Rush Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA
    Neurol Clin 19:129-44, vi-vii. 2001
    ..A discussion of idiopathic and secondary dystonia with focus on diagnosis and medical and surgical treatments encompasses the second part of the article...
  84. doi request reprint Movement disorders caused by medical disease
    Brandon Barton
    Department of Neurological Sciences, Movement Disorders Section, Rush University Medical Center, Chicago, Illinois 60612, USA
    Semin Neurol 29:97-110. 2009
    ..The spectrum of medical diseases associated with these four syndromes is reviewed in this article...
  85. doi request reprint Scales to assess psychosis in Parkinson's disease: Critique and recommendations
    Hubert H Fernandez
    Department of Neurology, McKnight Brain Institute University of Florida, Gainesville, Florida 32611, USA
    Mov Disord 23:484-500. 2008
    ..The CGIS is suggested as a secondary outcome scale to measure change and response to treatment over time...
  86. ncbi request reprint Repeated visual hallucinations in Parkinson's disease as disturbed external/internal perceptions: focused review and a new integrative model
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, Luxembourg
    Mov Disord 20:130-40. 2005
    ..This new conceptual framework permits an anatomical view of VH and suggests new, testable hypotheses regarding their pathophysiology and therapy...
  87. ncbi request reprint Movement Disorders Society Scientific Issues Committee report: SIC Task Force appraisal of clinical diagnostic criteria for Parkinsonian disorders
    Irene Litvan
    Movement Disorder Program, University of Louisville, KY 40205, USA
    Mov Disord 18:467-86. 2003
    ..In each of these areas, diagnosis continues to rest on clinical findings and the judicious use of ancillary studies...
  88. ncbi request reprint Non-linearity of Parkinson's disease progression: implications for sample size calculations in clinical trials
    Paulo Guimaraes
    Dept of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, 135 Cannon St Suite 303, Charleston, SC 29425, USA
    Clin Trials 2:509-18. 2005
    ..Models can help better understand behavior of the UPDRS after initiation of symptomatic therapy when scores will improve and eventually start deteriorating again...
  89. ncbi request reprint Multicenter, open-label, trial of sarizotan in Parkinson disease patients with levodopa-induced dyskinesias (the SPLENDID Study)
    C Warren Olanow
    Department of Neurology, Mount Sinai School of Medicine, New York, New York, USA
    Clin Neuropharmacol 27:58-62. 2004
  90. ncbi request reprint A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
    C Warren Olanow
    Department of Neurology, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Ann Neurol 54:403-14. 2003
    ..Fetal nigral transplantation currently cannot be recommended as a therapy for PD based on these results...
  91. ncbi request reprint The origins of scientific cinematography and early medical applications
    Alexandru C Barboi
    Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital, Milwaukee, WI 53226, USA
    Neurology 62:2082-6. 2004
    ..To examine the neurologic cinematographic contributions of Gheorghe Marinescu...
  92. ncbi request reprint Parkin mutations and susceptibility alleles in late-onset Parkinson's disease
    Sofia A Oliveira
    Department of Medicine and Center for Human Genetics, Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, NC 27710, USA
    Ann Neurol 53:624-9. 2003
    ..These findings suggest that mutations in Parkin contribute to the common form of PD and that heterozygous mutations, especially those lying in exon 7, act as susceptibility alleles for late-onset form of Parkinson disease...
  93. ncbi request reprint Hallucinations in Parkinson disease in the prelevodopa era
    Gilles Fenelon
    Department of Neurology, Hopital Henri Mondor, AP HP, Creteil, France
    Neurology 66:93-8. 2006
    ..Even with these limitations, historical descriptions of PD from the prelevodopa era suggest that hallucinations may be part of PD itself, especially in the context of late dementia, depression, or nonspecific encephalopathy...
  94. ncbi request reprint Open-label flexible-dose pilot study to evaluate the safety and tolerability of aripiprazole in patients with psychosis associated with Parkinson's disease
    Joseph H Friedman
    Parkinson Disease and Movement Disorders Center, NeuroHealth, Warwick, Rhode Island 02886, USA
    Mov Disord 21:2078-81. 2006
    ..While some patients had a favorable response, aripiprazole was associated with an exacerbation of motor symptoms. In this small study on psychosis in PD, aripiprazole did not appear promising...
  95. ncbi request reprint A responsive outcome for Parkinson's disease neuroprotection futility studies
    Jordan J Elm
    Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston, SC 29425, USA
    Ann Neurol 57:197-203. 2005
    ....
  96. ncbi request reprint Coping strategies for visual hallucinations in Parkinson's disease
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, Luxembourg
    Mov Disord 18:831-2. 2003
    ..We found that 36 of our 46 Parkinson's disease subjects with hallucinations (78%) used coping strategies: cognitive techniques in 69%; interactive techniques in 62%; and visual techniques in 33%...
  97. ncbi request reprint Short-term and practice effects of metronome pacing in Parkinson's disease patients with gait freezing while in the 'on' state: randomized single blind evaluation
    Esther Cubo
    Department of Neurology, Sanatorio del Rosario, Clinica de la Zarzuela, Principe de Vergara 53 28006, Madrid, Spain
    Parkinsonism Relat Disord 10:507-10. 2004
    ..In a randomized single blind parallel study, we tested the efficacy of an auditory metronome on walking speed and freezing in Parkinson's disease (PD) patients with freezing gait impairment during their 'on' function...
  98. pmc Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease
    Joelle M van der Walt
    Department of Medicine, and Center for Human Genetics, Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, NC 27710, USA
    Am J Hum Genet 72:804-11. 2003
    ..45; 95% CI 0.22-0.93; P=.03). Our results suggest that ND3 is an important factor in PD susceptibility among white individuals and could help explain the role of complex I in PD expression...
  99. ncbi request reprint The placebo treatments in neurosciences: New insights from clinical and neuroimaging studies
    Nico J Diederich
    Department of Neurosciences, Centre Hospitalier de Luxembourg, 4, Rue Barble, L 1210 Luxembourg City, Luxembourg
    Neurology 71:677-84. 2008
    ..In depression, PL partially imitates selective serotonin reuptake inhibitor-mediated brain activation. Diseases lacking major "top-down" or cortically based regulation may be less prone to PL-related improvement...
  100. ncbi request reprint Movement disorders associated with encephalitis lethargica: a video compilation
    Joel A Vilensky
    Department of Anatomy and Cell Biology, Indiana University School of Medicine, Fort Wayne, Indiana 46805, USA
    Mov Disord 21:1-8. 2006
    ..We describe the most complete record of EL and PEP moving images that have been preserved and make them available in edited form...
  101. ncbi request reprint Contribution of Jules Froment to the study of parkinsonian rigidity
    Emmanuel Broussolle
    Universite de Lyon, Universite Claude Bernard Lyon I, Faculté de médecine Lyon Sud, Lyon, France
    Mov Disord 22:909-14. 2007
    ..In their number, breadth, and originality, Froment's contributions to the study of parkinsonian rigidity remain currently relevant to clinical and neurophysiological issues of PD...

Research Grants1

  1. Multiple Factors Affecting Placebo Response in PD
    Christopher Goetz; Fiscal Year: 2004
    ..Defining these determinant influences will help enhance placebo responses in clinical practice and control them in clinical trials. ..