Denis A Evans

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..We hypothesized that black caregivers would exhibit lower levels of negative emotion and higher levels of positive emotion over time than whites...

..To test whether the level of hostility predicted the rate of cognitive decline in a community of older blacks and whites and whether the association varied as a function of race...

..High intake of vitamin E from food (tocopherol), but not from supplements (which usually contain alpha-tocopherol), is inversely associated with Alzheimer disease...

..To explore the association between adult day care (ADC) attendance and utilization of home-based formal services among people with Alzheimer's Disease (AD)...

..To examine the longitudinal association between decline in cognitive function and risk of elder self-neglect in a community-dwelling population...

..The aim of this study was to examine the associations of day care use and nursing home placement with the rate of cognitive decline in Alzheimer's disease...

..We examined the prevalence of self-neglect and its specific behaviors of hoarding, hygiene and other environmental hazards in a community-dwelling elderly population...

..We examined the relation of individual-level perceived discrimination to mortality in a biracial, population-based sample...

..To assess mortality associated with mild cognitive impairment (MCI) and Alzheimer disease (AD) among older African Americans and whites from an urban community...

..Dietary intake of fish and the omega-3 fatty acids have been associated with lower risk of Alzheimer disease and stroke...

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..White matter hyperintensity volume (WMHV), cerebral infarcts, and total brain volume (TBV) are associated with cognitive function, but few studies have examined these associations in the general population or whether they differ by race...

..To examine the relation of systolic and diastolic blood pressure to incident Alzheimer's disease (AD) and rate of cognitive change...

..The purpose of the current study was to examine the association of race with rate of cognitive decline in AD...

..Little information exists on the simultaneous effects of magnetic resonance (MR) infarct characteristics, that may increase the likelihood of dementia or lower cognitive function in community populations...

..Our findings suggest that husbands may be particularly psychologically vulnerable to the negative effects of their wives' cognitive impairment. This vulnerability may have a range of long-term health and caregiving implications...

..This study aimed to examine the cross-sectional association between cognitive function and elder abuse...

..Deficiencies in folate and vitamin B12 have been associated with neurodegenerative disease...

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..The objective of this study was to test the association of the personality traits of neuroticism and extraversion with risk of death in old age...

..225, p < .001) but remained robust. The racial differences increased slightly over time. Our findings support heightened awareness of depression in older Black populations...

..To test the association of rate of cognitive decline, an indicator of the severity of the underlying disease process, with risk of death in Alzheimer's disease (AD)...

..It is currently not known whether dietary intakes of folate and vitamins B12 and B6, co-factors in the methylation of homocysteine, protect against Alzheimer's disease...

..no use: mean difference = 0.12; p trend = 0.03). Overall, we found no relation between regular aspirin use and cognitive decline, but long-term use of ibuprofen may be related to decreased rates of cognitive decline in older persons...

..Few studies compare Alzheimer disease (AD) incidence among black and white subjects...

..Early-life adversity is related to adult health in old age but little is known about its relation with cognitive decline...

..It is important to preserve motor performance in individuals with AD because it influences physical function throughout the course of the disease...

..Measures of physical performance were used in intact and community populations. We examined upper and lower extremity physical performance tests among people with Alzheimer's disease...

..We examined racial differences in the cross-sectional association of education with physical and cognitive function performance in older adults...

..Although disability levels have been declining in older adults, there is little current information on racial differences in disability...

..Many of the foods abundant in the traditional Mediterranean diet, such as vegetables and fish, have been associated with slower cognitive decline...

..This study examined the association of cognitive and physical functions with age-related transition and progression of activities of daily living (ADL) disability in a population-based longitudinal cohort of nondisabled older adults...

..06), perceptual speed (p = 0.07) and naming (p = 0.08). The results suggest that the rate of cognitive decline in AD is slower in African-Americans compared with whites, particularly for episodic memory...

..The results from these waves must be combined for effective analysis of the relation among risk factors and incident disease...

..A 5-item version of the Daily Spiritual Experiences Scale (DSES) was used in the study. Multivariable linear regression models were used to examine the relationship between sociodemographic and psychosocial factors and DSES scores...

..Although report of self-neglect is more common among black older adults, the racial/ethnic differences in mortality remain unclear...

..The results suggest that early life socioeconomic level is related to level of cognition in late life but not to rate of cognitive decline or risk of AD...

..3 million in 2002 by the Aging, Demographics, and Memory Study (ADAMS), which is almost 50% less than the estimate of 4.5 million in 2000 derived from the Chicago Health and Aging Project...

..The apolipoprotein E (APOE) epsilon 4 allele is known to influence risk of AD but it has been difficult to establish whether it affects episodic memory differently from other cognitive functions...

..Promotion of walking behavior in older adults may require improvement of the safety and upkeep of the neighborhood environment...

..Depressive symptoms in Alzheimer's disease appear to follow a more predictable pattern of expression than previously described...

..Evidence from prospective epidemiologic studies and animal models suggests that intakes of dietary fats and copper may be associated with neurodegenerative diseases...

..Findings from studies investigating whether physical activity reduces the risk of cognitive decline in old age have been inconsistent...

..This longitudinal study examined whether the use of adult day care services delayed time to nursing home placement in persons with Alzheimer's disease...

..B-vitamin deficiencies have been associated with depression; however, there is very little prospective evidence from population-based studies of older adults...

..Elder self-neglect is a common public health issue, but it is unclear to what degree it is associated with cognitive function. This study aimed to examine the cross-sectional association between self-neglect and cognitive function...

..Previous studies raise the possibility that antioxidants protect against neurodegenerative diseases...

..059) after controlling for depressive symptoms. The results suggest that the tendency to experience psychological distress is associated with increased cognitive decline in old age...

..Oxidative processes have been suggested as elements in the development of Alzheimer disease (AD), but whether dietary intake of vitamin E and other antioxidant nutrients prevents its development is unknown...

..These findings indicate that the modified Harvard FFQ provides reasonable estimates of serum levels of vitamin E, vitamin C and beta-cryptoxanthin among CHAP participants...

..Findings for extraversion were mixed, and neither agreeableness nor openness was strongly related to mortality. The results suggest that personality is associated with mortality in old age...

..We investigated whether depressive symptoms, assessed by the 10-item Center for Epidemiological Studies Depression Scale (CES-D), predicted change in physical function in elderly adults...

..Dietary n-3 polyunsaturated fatty acids improve brain functioning in animal studies, but there is limited study of whether this type of fat protects against Alzheimer disease...

..The purpose of this study was to examine the association of blood pressure (BP) with change in lower limb function in older persons...

..In this study, we report on the association of fecal incontinence with physical disability and impaired cognitive function in a large bi-racial population of individuals aged 65 yr and older...

..Few studies have investigated the effects of dietary fats on the development of Alzheimer disease. We examined the associations between intake of specific types of fat and incident Alzheimer disease in a biracial community study...

..The modified Harvard SFFQ is a reasonable method of dietary assessment even in a population of older persons, some of whom are at advanced age, have chronic health conditions, and have cognitive impairment...

..Parkinsonianlike signs are common in older persons, but little is known about how their severity or rate of progression is related to the development of Alzheimer disease (AD) or decline in cognition...

..The authors tested the relationship of hallucinations and delusions to mortality in Alzheimer disease (AD)...

..These findings indicate that dementia caregivers exposed to agitated behaviors can benefit from psychosocial interventions, particularly those aimed at building behavioral management skills...

..This study examined the differences in levels of social networks and social engagement between older Blacks and Whites and racial differences in rates of change in social resources over time...

..The results suggest that negative affect in older persons, especially internally experienced distress, is associated with an increased mortality risk...

..A better SEP and a more stimulating cognitive milieu in childhood have small but significant effects on absolute level of cognitive function; however, they do not seem to protect against cognitive decline in old age...

..The results suggest that change in cognitive function in old age primarily reflects person-specific factors rather than an inevitable developmental process...

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..3 to 0.5 million. CONCLUSION: The number of persons with AD in the US population will continue to increase unless new discoveries facilitate prevention of the disease...

..In this study, we describe the prevalence of fecal incontinence by race, age, sex, the presence of major chronic conditions of stroke and diabetes, and the use of certain psychoactive medications...

..Nevertheless, the significant association observed with T wave nondipolar voltage suggests that the cardiac effects of heart disease are associated with cognitive declines...

..Time when behavior peaked differed by type of behavior and by facility, and there was substantial heterogeneity in behavior patterns...

..06; 95% CI: 0.89-1.27). Our results suggest that racial differences in HRQOL are associated with the combined effects of social disadvantage, poor physical health, and lower cognitive function...

..The cross-sectional association between blood pressure and cognitive functions is small and curvilinear and more apparent in persons with cardiovascular conditions...

..To examine the prevalence of perceived discrimination in an older biracial population and to examine its correlation with depressive symptoms...

..Frequent participation in cognitively stimulating activities has been hypothesized to reduce risk of Alzheimer disease (AD), but prospective data regarding an association are lacking...

..We examined the association of relative weight with mobility and changes in mobility over time and whether these associations differed by race...

..We sought to identify predictors of beginning and ending caregiving...

..The Medicare Prescription Drug Benefit (Part D) program debuted in January 2006. We ascertained the sociodemographic and health characteristics of Blacks and Whites who enrolled in the early stages of the program...

..This longitudinal study examines the association between physical function decline and the risk of elder self-neglect in a community-dwelling population...

..Overall, these findings suggest that lower levels of pulmonary function and muscle strength are relatively independently associated with the development of mobility disability in the elderly...