C L Comella

Summary

Affiliation: Rush University Medical Center
Country: USA

Publications

  1. doi request reprint Treatment of restless legs syndrome
    Cynthia L Comella
    Movement Disorders Section, Department of Neurological Sciences, Rush Medical College, 1725 West Harrison Street, Suite 755, Chicago, IL, 60612, USA
    Neurotherapeutics 11:177-87. 2014
  2. ncbi request reprint Nocturnal activity with nighttime pergolide in Parkinson disease: a controlled study using actigraphy
    Cynthia L Comella
    Department of Neurologic Sciences, Rush University Medical Center, 1725 W Harrison, Chicago, IL 60612, USA
    Neurology 64:1450-1. 2005
  3. ncbi request reprint Comparison of botulinum toxin serotypes A and B for the treatment of cervical dystonia
    C L Comella
    Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 65:1423-9. 2005
  4. ncbi request reprint Treatment of cervical dystonia with botulinum toxins
    C L Comella
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Eur J Neurol 13:16-20. 2006
  5. ncbi request reprint Can families be screened for cervical dystonia using a telephone interview?
    Cynthia L Comella
    Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Nat Clin Pract Neurol 2:20-1. 2006
  6. ncbi request reprint Sleep disturbances in Parkinson's disease
    Cynthia L Comella
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Rush Medical College, 1725 West Harrison, Suite 755, Chicago, IL 60612, USA
    Curr Neurol Neurosci Rep 3:173-80. 2003
  7. ncbi request reprint The treatment of cervical dystonia with botulinum toxins
    C L Comella
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    J Neural Transm 115:579-83. 2008
  8. ncbi request reprint Restless legs syndrome: treatment with dopaminergic agents
    Cynthia L Comella
    Department of Neurological Sciences, Rush Medical Center, Chicago, IL 60612, USA
    Neurology 58:S87-92. 2002
  9. doi request reprint Sleep disorders in Parkinson's disease: an overview
    Cynthia L Comella
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 22:S367-73. 2007
  10. ncbi request reprint Botulinum toxins in neurological disease
    Cynthia L Comella
    Department of Neurological Sciences, Rush University Medical Center, 1725 West Harrison, Chicago, Illinois 60612, USA
    Muscle Nerve 29:628-44. 2004

Collaborators

Detail Information

Publications31

  1. doi request reprint Treatment of restless legs syndrome
    Cynthia L Comella
    Movement Disorders Section, Department of Neurological Sciences, Rush Medical College, 1725 West Harrison Street, Suite 755, Chicago, IL, 60612, USA
    Neurotherapeutics 11:177-87. 2014
    ..Other agents, including the opioids and clonazepam do not have sufficient evidence to recommend them as treatment for RLS, although in an individual patient, they may provide benefit. ..
  2. ncbi request reprint Nocturnal activity with nighttime pergolide in Parkinson disease: a controlled study using actigraphy
    Cynthia L Comella
    Department of Neurologic Sciences, Rush University Medical Center, 1725 W Harrison, Chicago, IL 60612, USA
    Neurology 64:1450-1. 2005
    ..The pergolide group (n = 10) worsened in actigraphic measures of sleep efficiency and sleep fragmentation vs the placebo group (n = 12). Side effects were more frequent in the pergolide group...
  3. ncbi request reprint Comparison of botulinum toxin serotypes A and B for the treatment of cervical dystonia
    C L Comella
    Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 65:1423-9. 2005
    ..To directly compare two serotypes of botulinum toxin (BoNTA and BoNTB) in cervical dystonia (CD) using a randomized, double-blind, parallel-arm study design...
  4. ncbi request reprint Treatment of cervical dystonia with botulinum toxins
    C L Comella
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Eur J Neurol 13:16-20. 2006
    ..Although many aspects of the technique of injection have not been adequately studied, general guidelines are available...
  5. ncbi request reprint Can families be screened for cervical dystonia using a telephone interview?
    Cynthia L Comella
    Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Nat Clin Pract Neurol 2:20-1. 2006
  6. ncbi request reprint Sleep disturbances in Parkinson's disease
    Cynthia L Comella
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Rush Medical College, 1725 West Harrison, Suite 755, Chicago, IL 60612, USA
    Curr Neurol Neurosci Rep 3:173-80. 2003
    ..Treatment is aimed toward improving night-time sleep and daytime drowsiness by addressing the causative factors...
  7. ncbi request reprint The treatment of cervical dystonia with botulinum toxins
    C L Comella
    Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    J Neural Transm 115:579-83. 2008
    ..However, it is likely that each brand and serotype may differ in immunogenic potential and occurrence of secondary unresponsiveness, an issue that is currently under active investigation...
  8. ncbi request reprint Restless legs syndrome: treatment with dopaminergic agents
    Cynthia L Comella
    Department of Neurological Sciences, Rush Medical Center, Chicago, IL 60612, USA
    Neurology 58:S87-92. 2002
    ..Augmentation, although it may be associated with chronic agonist use, is usually mild and responsive to additional dosing. The direct dopamine receptor agonists have largely replaced levodopa as the most effective treatment for RLS...
  9. doi request reprint Sleep disorders in Parkinson's disease: an overview
    Cynthia L Comella
    Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Mov Disord 22:S367-73. 2007
    ..Appropriate diagnosis of the sleep disturbance affecting a PD patient can lead to specific treatments that can consolidate nocturnal sleep and enhance daytime alertness...
  10. ncbi request reprint Botulinum toxins in neurological disease
    Cynthia L Comella
    Department of Neurological Sciences, Rush University Medical Center, 1725 West Harrison, Chicago, Illinois 60612, USA
    Muscle Nerve 29:628-44. 2004
    ..This review focuses on the pharmacology, electrophysiology, immunology, and application of botulinum toxin in selected neurological disorders...
  11. ncbi request reprint Menstrual-related changes in motoric function in women with Parkinson's disease
    K Kompoliti
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Rush University, Chicago, IL, USA
    Neurology 55:1572-5. 2000
    ..Although PD severity fluctuated during the study period, there was no significant correlation between the objective or subjective measures of parkinsonism and estrogen and progesterone levels...
  12. ncbi request reprint Muscle activation patterns in point-to-point and reversal movements in healthy, older subjects and in subjects with Parkinson's disease
    K D Pfann
    The Department of Movement Science M C 194, University of Illinois at Chicago, 901 West Roosevelt Road, Chicago, IL 60608, USA
    Exp Brain Res 157:67-78. 2004
    ....
  13. pmc High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease
    D E Vaillancourt
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 West Taylor, 650 AHSB, MC 994, Chicago, IL 60612, USA
    Neurology 72:1378-84. 2009
    ....
  14. ncbi request reprint Daytime sleepiness, agonist therapy, and driving in Parkinson disease
    Cynthia L Comella
    JAMA 287:509-11. 2002
  15. ncbi request reprint Efficacy and safety of botulinum type A toxin (Dysport) in cervical dystonia: results of the first US randomized, double-blind, placebo-controlled study
    Daniel Truong
    The Parkinson s and Movement Disorders Institute, Fountain Valley, California 92708, USA
    Mov Disord 20:783-91. 2005
    ..These results confirm previous reports that Dysport (500 units) is safe, effective, and well-tolerated in patients with cervical dystonia...
  16. ncbi request reprint Association of daytime napping and Parkinsonian signs in Alzheimer's disease
    Margaret Park
    Sleep Disorders Center, Rush University Medical Center, 710 South Paulina Street, JRB 6th Floor, Chicago, IL 60612, USA
    Sleep Med 7:614-8. 2006
    ..The purpose of this study was to determine whether more Parkinsonian motor signs exist in AD patients with more reported daytime napping compared to AD patients without daytime napping...
  17. ncbi request reprint Parkinson's disease--Part 2: Treatment of motor symptoms
    Daniel Weintraub
    Department of Neurological Sciences, University of Pennsylvania, 330 S 9th St, Philadelphia, PA 19107, USA
    Am J Manag Care 14:S49-58. 2008
    ..Cost-effectiveness is a major consideration for managed care and is also analyzed for many available treatment options...
  18. ncbi request reprint Treatment of dystonia
    Jennifer G Goldman
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, 1725 W Harrison Street, Suite 755, Chicago, IL 60612, USA
    Clin Neuropharmacol 26:102-8. 2003
    ..Studies in functional outcome and quality of life further support the importance of discovering safe and effective means to treat dystonia. An algorithmic approach may be useful to guide the physician along the various treatment choices...
  19. ncbi request reprint Parkinson's disease--Part 1: Pathophysiology, symptoms, burden, diagnosis, and assessment
    Daniel Weintraub
    University of Pennsylvania, Philadelphia, PA, USA
    Am J Manag Care 14:S40-8. 2008
    ..This article provides a brief review of the epidemiology, pathophysiology, clinical course, and burden of PD...
  20. ncbi request reprint Parkinson's disease--Part 3: Neuropsychiatric symptoms
    Daniel Weintraub
    Department of Psychiatry and Neurology, University of Pennsylvania, 3615 Chestnut St, Philadelphia, PA 19104, USA
    Am J Manag Care 14:S59-69. 2008
    ..This article looks at useful screening measures to help clinicians recognize neuropsychiatric symptoms and offers suggestions for their effective treatment...
  21. doi request reprint Long-term treatment with botulinum toxin type A in cervical dystonia has low immunogenicity by mouse protection assay
    Mitchell F Brin
    Allergan, Inc, Global Drug Development, Irvine, California, USA
    Mov Disord 23:1353-60. 2008
    ..The current formulation of BoNTA rarely causes neutralizing antibody formation in CD subjects treated < or =4 years...
  22. pmc Changes in the relationship between movement velocity and movement distance in primary focal hand dystonia
    Janey Prodoehl
    Department of Kinesiology and Nutrition, University of Illinois, Chicago, Chicago, IL 60612, USA
    J Mot Behav 40:301-13. 2008
    ..Underactivation of the 1st agonist burst appears to be the most likely reason to explain slowing...
  23. ncbi request reprint Force control and disease severity in Parkinson's disease
    Julie A Robichaud
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, Indiana University, Indianapolis, Indiana 46202, USA
    Mov Disord 20:441-50. 2005
    ..These measures provide objective quantification of the severity of motor impairment that can be used to investigate the efficacy of different interventions in individuals with PD...
  24. ncbi request reprint Effect of medication on EMG patterns in individuals with Parkinson's disease
    Julie A Robichaud
    School of Kinesiology, University of Illinois at Chicago, Chicago, Illinois 60608, USA
    Mov Disord 17:950-60. 2002
    ..These results show that medication does not alter the temporal profile of EMG activation...
  25. ncbi request reprint Restless legs syndrome in Parkinson's disease and other neurodegenerative diseases of the central nervous system
    Alex Iranzo
    Neurology Service, Hospital Clínic and Institut d Investigació Biomèdiques August Pi i Sunyer IDIBAPS, Barcelona, Spain
    Mov Disord 22:S424-30. 2007
    ....
  26. ncbi request reprint Rating scales for dystonia: a multicenter assessment
    Cynthia L Comella
    Rush Presbyterian St Lukes Medical Center, Suite 755, 1725 West Harrison, Chicago, IL 60612
    Mov Disord 18:303-12. 2003
    ..Among scales, the total scores correlated (Pearson's r, 0.977-0.983). Overall, 74% of raters found the GDS the easiest to apply. The GDS with its simplicity and ease of application may be the most useful dystonia rating scale...
  27. ncbi request reprint Benefits and risks of pharmacological treatments for essential tremor
    Kelly E Lyons
    University of Kansas Medical Center, Kansas City, Kansas 66160, USA
    Drug Saf 26:461-81. 2003
    ..The use of medication and/or surgery can provide adequate tremor control in the majority of the patients...
  28. ncbi request reprint Strength deficits in primary focal hand dystonia
    Janey Prodoehl
    Department of Movement Sciences, College of Applied Health Sciences, University of Illinois at Chicago, Illinois 60612, USA
    Mov Disord 21:18-27. 2006
    ..The amount of co-contraction of antagonistic muscles was not significantly different between the two groups. These results are discussed in the context of dystonia as a disorder resulting from dysfunction of basal ganglia output...
  29. ncbi request reprint Greater impairment of extension movements as compared to flexion movements in Parkinson's disease
    Julie A Robichaud
    Department of Human Movement Sciences M C 194, University of Illinois at Chicago, 901 West Roosevelt Road, Chicago, IL 60608, USA
    Exp Brain Res 156:240-54. 2004
    ..The results are consistent with the hypothesis that there is a differential impairment of neural activation of extensor muscles of the arm as compared to flexor muscles in subjects with PD...
  30. ncbi request reprint Restless legs syndrome
    Ilia Itin
    Rush University Medical Center, Section of Movement Disorders, 1725 West Harrison Street, Suite 755, Chicago, IL 60612, USA
    Prim Care 32:435-48. 2005
    ..The currently available medications are highly effective in treating RLS. The knowledge of clinical presentation and diagnostic features of RLS will empower the primary care practitioners to effectively treat their patients who have RLS...
  31. ncbi request reprint Rating scale for psychogenic movement disorders: scale development and clinimetric testing
    Vanessa K Hinson
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina, USA
    Mov Disord 20:1592-7. 2005
    ..The PMD scale adequately captures the complex movements of PMDs and can be used to assess PMDs and test the efficacy of intervention strategies...