Patricia A Boyle,

Summary

Affiliation: Rush University Medical Center
Country: USA

Publications

  1. pmc Correlates of health and financial literacy in older adults without dementia
    Jarred S Bennett
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL, USA
    BMC Geriatr 12:30. 2012
  2. pmc Poor decision making is a consequence of cognitive decline among older persons without Alzheimer's disease or mild cognitive impairment
    Patricia A Boyle
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois, USA
    PLoS ONE 7:e43647. 2012
  3. pmc Association of cognition with temporal discounting in community based older persons
    Patricia A Boyle
    Rush University Medical Center, Rush Alzheimer s Disease Center, 600 S, Paulina, Suite 1020B, Chicago, IL 60612, USA
    BMC Geriatr 12:48. 2012
  4. pmc Effect of purpose in life on the relation between Alzheimer disease pathologic changes on cognitive function in advanced age
    Patricia A Boyle
    Rush Alzheimer s Disease Center, 600 S Paulina Ave, Ste 1020B, Chicago, IL 60612, USA
    Arch Gen Psychiatry 69:499-505. 2012
  5. pmc Combinations of motor measures more strongly predict adverse health outcomes in old age: the rush memory and aging project, a community-based cohort study
    Aron S Buchman
    Department of Neurological Sciences, Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    BMC Med 9:42. 2011
  6. pmc Loneliness and the rate of motor decline in old age: the Rush Memory and Aging Project, a community-based cohort study
    Aron S Buchman
    Department of Neurological Sciences, Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S, Paulina, Chicago, Illinois 60612, USA
    BMC Geriatr 10:77. 2010
  7. ncbi request reprint Mild cognitive impairment: risk of Alzheimer disease and rate of cognitive decline
    P A Boyle
    Rush Alzheimer s Disease Center, Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 67:441-5. 2006
  8. pmc The APOE epsilon4 allele is associated with incident mild cognitive impairment among community-dwelling older persons
    Patricia A Boyle
    Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Neuroepidemiology 34:43-9. 2010
  9. pmc Purpose in life is associated with mortality among community-dwelling older persons
    Patricia A Boyle
    Rush Alzheimer s Disease Center, Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Psychosom Med 71:574-9. 2009
  10. ncbi request reprint Physical activity is associated with incident disability in community-based older persons
    Patricia A Boyle
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Am Geriatr Soc 55:195-201. 2007

Detail Information

Publications54

  1. pmc Correlates of health and financial literacy in older adults without dementia
    Jarred S Bennett
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL, USA
    BMC Geriatr 12:30. 2012
    ..Our study examines the relation of health and financial literacy with health promoting behaviors and health status among community-based older persons...
  2. pmc Poor decision making is a consequence of cognitive decline among older persons without Alzheimer's disease or mild cognitive impairment
    Patricia A Boyle
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois, USA
    PLoS ONE 7:e43647. 2012
    ..The objective of this study was to test the hypothesis that poor decision making is a consequence of cognitive decline among older persons without Alzheimer's disease or mild cognitive impairment...
  3. pmc Association of cognition with temporal discounting in community based older persons
    Patricia A Boyle
    Rush University Medical Center, Rush Alzheimer s Disease Center, 600 S, Paulina, Suite 1020B, Chicago, IL 60612, USA
    BMC Geriatr 12:48. 2012
    ..The objective of this study was to test the hypothesis that cognitive function is negatively associated with temporal discounting in old age...
  4. pmc Effect of purpose in life on the relation between Alzheimer disease pathologic changes on cognitive function in advanced age
    Patricia A Boyle
    Rush Alzheimer s Disease Center, 600 S Paulina Ave, Ste 1020B, Chicago, IL 60612, USA
    Arch Gen Psychiatry 69:499-505. 2012
    ..Purpose in life is associated with a substantially reduced risk of Alzheimer disease (AD), but the neurobiologic basis of this protective effect remains unknown...
  5. pmc Combinations of motor measures more strongly predict adverse health outcomes in old age: the rush memory and aging project, a community-based cohort study
    Aron S Buchman
    Department of Neurological Sciences, Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    BMC Med 9:42. 2011
    ..We tested the hypothesis that combinations of motor constructs more strongly predict adverse health outcomes in older people...
  6. pmc Loneliness and the rate of motor decline in old age: the Rush Memory and Aging Project, a community-based cohort study
    Aron S Buchman
    Department of Neurological Sciences, Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S, Paulina, Chicago, Illinois 60612, USA
    BMC Geriatr 10:77. 2010
    ..We tested the hypothesis that feeling alone is associated with the rate of motor decline in community-dwelling older persons...
  7. ncbi request reprint Mild cognitive impairment: risk of Alzheimer disease and rate of cognitive decline
    P A Boyle
    Rush Alzheimer s Disease Center, Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 67:441-5. 2006
    ..To examine the extent to which persons with mild cognitive impairment (MCI) have an increased risk of Alzheimer disease (AD) and a more rapid rate of decline in cognitive function compared to similar persons without cognitive impairment...
  8. pmc The APOE epsilon4 allele is associated with incident mild cognitive impairment among community-dwelling older persons
    Patricia A Boyle
    Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Neuroepidemiology 34:43-9. 2010
    ..The apolipoprotein E (APOE) epsilon4 allele is a well-known risk factor for the development of Alzheimer's disease, but little is known about the association of the epsilon4 allele with incident mild cognitive impairment (MCI)...
  9. pmc Purpose in life is associated with mortality among community-dwelling older persons
    Patricia A Boyle
    Rush Alzheimer s Disease Center, Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Psychosom Med 71:574-9. 2009
    ..To assess the association between purpose in life and all-cause mortality in community-dwelling elderly persons...
  10. ncbi request reprint Physical activity is associated with incident disability in community-based older persons
    Patricia A Boyle
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Am Geriatr Soc 55:195-201. 2007
    ....
  11. ncbi request reprint Lower extremity motor function and disability in mild cognitive impairment
    P A Boyle
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    Exp Aging Res 33:355-71. 2007
    ..These findings suggest that lower extremity motor dysfunction is common and contributes to disability in MCI, but lower extremity motor dysfunction in MCI does not appear to be explained by the vascular factors examined in this study...
  12. doi request reprint Processing resources reduce the effect of Alzheimer pathology on other cognitive systems
    P A Boyle
    Rush Alzheimer s Disease Center, Department of Behavioral Sciences, Rush University Medical Center, 600 S Paulina, 1020B, Chicago, IL 60612, USA
    Neurology 70:1534-42. 2008
    ..If this is an effective compensatory strategy, then involvement of additional cognitive systems may help maintain function in other cognitive systems despite the accumulation of pathology...
  13. pmc Physical frailty is associated with incident mild cognitive impairment in community-based older persons
    Patricia A Boyle
    Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Facility, Suite 1020B, 600 South Paulina Street, Chicago, IL 60612, USA
    J Am Geriatr Soc 58:248-55. 2010
    ..To test the hypothesis that physical frailty is associated with risk of mild cognitive impairment (MCI)...
  14. pmc Effect of a purpose in life on risk of incident Alzheimer disease and mild cognitive impairment in community-dwelling older persons
    Patricia A Boyle
    Rush Alzheimer s Disease Center, 600 S Paulina, Ste 1020B, Chicago, IL 60612, USA
    Arch Gen Psychiatry 67:304-10. 2010
    ..Emerging data suggest that psychological and experiential factors are associated with risk of Alzheimer disease (AD), but the association of purpose in life with incident AD is unknown...
  15. ncbi request reprint Parkinsonian signs in subjects with mild cognitive impairment
    P A Boyle
    Rush Alzheimer s Disease Center, Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 65:1901-6. 2005
    ....
  16. pmc Purpose in life is associated with a reduced risk of incident disability among community-dwelling older persons
    Patricia A Boyle
    From the Rush Alzheimer s Disease Center, Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA
    Am J Geriatr Psychiatry 18:1093-102. 2010
    ..Purpose in life is thought to be associated with positive health outcomes in old age, but its association with disability is unknown...
  17. pmc Association between life space and risk of mortality in advanced age
    Patricia A Boyle
    Rush Alzheimer s Disease Center, Chicago, Illinois 60612, USA
    J Am Geriatr Soc 58:1925-30. 2010
    ..To examine the association between life space, a measure of functional status that describes the range of movement through the environment covered during daily functioning, and the risk of mortality in older community-based persons...
  18. pmc Cognitive function is associated with risk aversion in community-based older persons
    Patricia A Boyle
    Rush University Medical Center, Rush Alzheimer s Disease Center, 600 S Paulina, Chicago, IL 60612, USA
    BMC Geriatr 11:53. 2011
    ....
  19. pmc Association of muscle strength with the risk of Alzheimer disease and the rate of cognitive decline in community-dwelling older persons
    Patricia A Boyle
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Arch Neurol 66:1339-44. 2009
    ....
  20. pmc Neurodegenerative basis of age-related cognitive decline
    R S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 South Paulina Ave, Suite 1038, Chicago, IL 60612, USA
    Neurology 75:1070-8. 2010
    ..To assess the contribution of dementia-related neuropathologic lesions to age-related and disease-related change in cognitive function...
  21. pmc Pulmonary function, muscle strength and mortality in old age
    A S Buchman
    Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, United States
    Mech Ageing Dev 129:625-31. 2008
    ..Overall, these findings suggest that pulmonary function may partially account for the association of muscle strength and mortality...
  22. pmc Respiratory muscle strength predicts decline in mobility in older persons
    A S Buchman
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Neuroepidemiology 31:174-80. 2008
    ..To test the hypothesis that respiratory muscle strength is associated with the rate of change in mobility even after controlling for leg strength and physical activity...
  23. pmc Kidney function is associated with the rate of cognitive decline in the elderly
    Aron S Buchman
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 73:920-7. 2009
    ..We tested the hypothesis that impaired kidney function in the elderly is associated with a more rapid rate of cognitive decline...
  24. ncbi request reprint Chronic distress and incidence of mild cognitive impairment
    R S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 68:2085-92. 2007
    ..Here we test the hypothesis that chronic psychological distress is associated with increased incidence of MCI in old age...
  25. ncbi request reprint Physical activity and motor decline in older persons
    A S Buchman
    Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Facility, Suite 1038, 600 South Paulina Street, Chicago, Illinois 60612, USA
    Muscle Nerve 35:354-62. 2007
    ..Thus, higher levels of physical activity are associated with a slower rate of motor decline in older persons...
  26. pmc Cognitive activity and the cognitive morbidity of Alzheimer disease
    R S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Neurology 75:990-6. 2010
    ..To test the hypothesis that frequent cognitive activity predicts slower cognitive decline before dementia onset in Alzheimer disease (AD) and faster decline thereafter...
  27. pmc Memory complaints are related to Alzheimer disease pathology in older persons
    L L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Facility, 600 S Paulina, Suite 1038, Chicago, IL 60612, USA
    Neurology 67:1581-5. 2006
    ..To study the relationship between Alzheimer disease (AD) pathology and memory complaints proximate to death...
  28. pmc Pulmonary function, muscle strength, and incident mobility disability in elders
    Aron S Buchman
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 South Paulina Street, Chicago, IL 60612, USA
    Proc Am Thorac Soc 6:581-7. 2009
    ..Overall, these findings suggest that lower levels of pulmonary function and muscle strength are relatively independently associated with the development of mobility disability in the elderly...
  29. pmc Loss of basic lexical knowledge in old age
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 South Paulina Ave, Suite 1038, Chicago, IL 60612, USA
    J Neurol Neurosurg Psychiatry 82:369-72. 2011
    ..Basic lexical skills are hypothesised to be relatively preserved in mild dementia, but clinical studies have reported inconsistent results...
  30. pmc Musculoskeletal pain and incident disability in community-dwelling older adults
    Aron S Buchman
    Rush University Medical Center, Chicago, Illinois 60612, USA
    Arthritis Care Res (Hoboken) 62:1287-93. 2010
    ..To test the hypothesis that the number of areas of musculoskeletal pain reported is related to incident disability...
  31. pmc Musculoskeletal pain is associated with incident mobility disability in community-dwelling elders
    Raj C Shah
    Rush Alzheimer s Disease Center, 600 South Paulina, Suite 1038, Chicago, IL 60612, USA
    J Gerontol A Biol Sci Med Sci 66:82-8. 2011
    ..We tested the hypothesis that musculoskeletal pain is associated with first occurrence of severe mobility disability...
  32. pmc Relation of late-life social activity with incident disability among community-dwelling older adults
    Bryan D James
    Rush University Medical Center, Room 1038, 600 South Paulina Street, Chicago, IL 60612, USA
    J Gerontol A Biol Sci Med Sci 66:467-73. 2011
    ..We tested the hypothesis that a higher level of social activity was associated with decreased risk of incident disability in older adults...
  33. ncbi request reprint Olfactory identification and incidence of mild cognitive impairment in older age
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Ste 1038, Chicago, IL 60612, USA
    Arch Gen Psychiatry 64:802-8. 2007
    ..Mild cognitive impairment (MCI) is often a precursor to Alzheimer disease, but knowledge about factors that predict its development is limited...
  34. pmc Olfactory impairment in presymptomatic Alzheimer's disease
    Robert S Wilson
    Department of Neurological Sciences, Rush Alzheimer s Disease Center, Rush University Medical Cetner, Chicago, Illinois 60612, USA
    Ann N Y Acad Sci 1170:730-5. 2009
    ....
  35. ncbi request reprint Physical activity and leg strength predict decline in mobility performance in older persons
    Aron S Buchman
    Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Am Geriatr Soc 55:1618-23. 2007
    ..To assess the extent to which physical activity and leg strength are associated with change in mobility in older persons...
  36. ncbi request reprint Grip strength and the risk of incident Alzheimer's disease
    Aron S Buchman
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Neuroepidemiology 29:66-73. 2007
    ..Declining strength in old age is associated with an increased risk of AD...
  37. ncbi request reprint Frailty is associated with incident Alzheimer's disease and cognitive decline in the elderly
    Aron S Buchman
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Psychosom Med 69:483-9. 2007
    ..To assess the association between frailty and incident Alzheimer's disease (AD) and cognitive decline. Frailty is common in older persons and associated with adverse health outcomes...
  38. ncbi request reprint Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons
    Julie A Schneider
    Rush Alzheimer s Disease Center and Rush Institute for Healthy Aging, Department of Neurological Sciences, Rush University Medical Center, 600 South Paulina Street, Chicago, IL 60612, USA
    Ann Neurol 62:59-66. 2007
    ..Examine the effects of subcortical infarcts with Alzheimer's disease (AD) pathology on dementia, episodic memory, and other cognitive abilities in older persons...
  39. ncbi request reprint Change in motor function and risk of mortality in older persons
    Aron S Buchman
    Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    J Am Geriatr Soc 55:11-9. 2007
    ..To assess the association between change in motor function and mortality...
  40. pmc Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment
    Robert S Wilson
    Rush Alzheimer s Disease Center, Department of Neurological Science, Rush University Medical Center, 600 S Paulina Ave, Ste 1038, Chicago, IL 60612, USA
    Arch Neurol 68:351-6. 2011
    ..To characterize the course of cognitive decline during the prodromal phase of Alzheimer disease...
  41. pmc Association between late-life social activity and motor decline in older adults
    Aron S Buchman
    Departments of Neurological Sciences, Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Facility, Chicago, IL 60612, USA
    Arch Intern Med 169:1139-46. 2009
    ..Our objective was to test the hypothesis that late-life social activity is related to the rate of change in motor function in old age...
  42. pmc Apolipoprotein E e4 allele is associated with more rapid motor decline in older persons
    Aron S Buchman
    Rush Alzheimer s Disease Center, Armour Academic Facility, Rush University Medical Center, Chicago, IL 60612, USA
    Alzheimer Dis Assoc Disord 23:63-9. 2009
    ..These results suggest that the presence of epsilon4 allele is a risk factor for more rapid motor decline in the elderly...
  43. ncbi request reprint Executive impairments predict functional declines in vascular dementia
    Patricia A Boyle
    Department of Neurology, Boston University School of Medicine, Alzheimer s Disease Center, Boston, MA, USA
    Clin Neuropsychol 18:75-82. 2004
    ..These findings demonstrate that baseline executive dysfunction is a significant and powerful predictor of future functional decline in individuals with VaD...
  44. ncbi request reprint Assessment and prediction of functional impairment in vascular dementia
    Patricia A Boyle
    Department of Neurology, Boston University School of Medicine, Alzheimer s Disease Center, 715 Albany St, B7800, Boston, MA 02118, USA
    Expert Rev Neurother 4:109-14. 2004
    ..Also, the potential use of executive dysfunction as a marker for instrumental activities of daily living impairment is discussed and recommendations for clinical practice and future research are provided...
  45. ncbi request reprint Cognitive and motor impairments predict functional declines in patients with vascular dementia
    Patricia A Boyle
    Department of Psychiatry, Brown Medical School, Providence, RI 02912, USA
    Int J Geriatr Psychiatry 17:164-9. 2002
    ..Patients with VaD display diverse cognitive and motor deficits, however, and relationships between these impairments and independent living abilities remain unclear...
  46. ncbi request reprint Assessing and predicting functional impairment in Alzheimer's disease: the emerging role of frontal system dysfunction
    Patricia A Boyle
    Department of Neurology, Alzheimer s Disease Center, Boston University School of Medicine, 715 Albany Street, B7800, Boston, MA 02118, USA
    Curr Psychiatry Rep 6:20-4. 2004
    ..The emerging role of frontal system dysfunction as an important determinant of ADL impairment is discussed, and recommendations for clinical practice and future research are provided...
  47. ncbi request reprint Cognitive and neurologic predictors of functional impairment in vascular dementia
    Patricia A Boyle
    Department of Psychiatry, Brown Medical School, Providence, RI 02912, USA
    Am J Geriatr Psychiatry 11:103-6. 2003
    ..The purpose of this study is to investigate associations between executive dysfunction, neuroimaging findings, and functional impairment in patients with vascular dementia (VaD)...
  48. ncbi request reprint Tests of executive function predict instrumental activities of daily living in community-dwelling older individuals
    Deborah A Cahn-Weiner
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island, USA
    Appl Neuropsychol 9:187-91. 2002
    ..These findings suggest that different aspects of frontal and executive functions may be related to IADLs, depending on the type of assessment instrument used. Key words: activities of daily living, executive function, older adults..
  49. ncbi request reprint Executive dysfunction and apathy predict functional impairment in Alzheimer disease
    Patricia A Boyle
    Brown Medical School, Providence, RI, USA
    Am J Geriatr Psychiatry 11:214-21. 2003
    ..The purpose of this study was to examine the extent to which executive cognitive dysfunction and frontally-mediated behavioral disturbances are associated with functional impairment in patients with mild-to-moderate Alzheimer disease (AD)...
  50. ncbi request reprint The diagnosis of neurological disorders in older adults
    Howard N Garb
    Pittsburgh Veterans Administration Healthcare System, University of Pittsburgh, 15206 1297, USA
    Assessment 10:129-34. 2003
    ..The results from this study indicate that age bias is not as serious a problem among neuropsychologists as many psychologists once believed...
  51. ncbi request reprint Treating apathy in Alzheimer's disease
    Patricia A Boyle
    Department of Neurology, Boston University School of Medicine, Boston, MA 02116, USA
    Dement Geriatr Cogn Disord 17:91-9. 2004
    ..The potential benefits of other pharmacologic agents and combined pharmacologic-behavioral interventions are also discussed, and recommendations for future research are provided...
  52. ncbi request reprint The relationship of MRI subcortical hyperintensities to treatment response in a trial of sertraline in geriatric depressed outpatients
    Stephen Salloway
    Department of Neurology, Butler Hospital Providence, RI 02906, USA
    Am J Geriatr Psychiatry 10:107-11. 2002
    ..The association between SH and antidepressant treatment response in depressed geriatric outpatients remains unclear and deserves further investigation...
  53. ncbi request reprint Project CARE: a randomized controlled trial of a behavioral intervention group for Alzheimer's disease caregivers
    Judith G Gonyea
    Boston University, School of Social Work, 264 Bay State Road, Boston, MA 02215, and Department of Psychology, Edith Norse Rogers Veterans Memorial Hospital, Bedford, USA
    Gerontologist 46:827-32. 2006
    ....
  54. ncbi request reprint Subjective appraisal of Alzheimer's disease caregiving: the role of self-efficacy and depressive symptoms in the experience of burden
    Judith G Gonyea
    School of Social Work, Boston University, Boston, Massachusetts, USA
    Am J Alzheimers Dis Other Demen 20:273-80. 2005
    ..These findings suggest that caregiver interventions aimed to reduce burden may benefit from the incorporation of specific strategies to increase self-efficacy and decrease depressive symptoms...