Julia L Bienias

Summary

Affiliation: Rush University Medical Center
Country: USA

Publications

  1. ncbi request reprint Design of the Chicago Health and Aging Project (CHAP)
    Julia L Bienias
    Rush Institute for Healthy Aging, Rush University, Chicago, IL 60612, USA
    J Alzheimers Dis 5:349-55. 2003
  2. pmc Race differences in emotional adaptation of family caregivers
    Kimberly A Skarupski
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612 3227, USA
    Aging Ment Health 13:715-24. 2009
  3. pmc Hostility and change in cognitive function over time in older blacks and whites
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    Psychosom Med 71:652-8. 2009
  4. ncbi request reprint Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Chicago, IL 60612, USA
    Arch Gen Psychiatry 64:1204-12. 2007
  5. ncbi request reprint Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change
    Martha Clare Morris
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Clin Nutr 81:508-14. 2005
  6. ncbi request reprint Fish consumption and cognitive decline with age in a large community study
    Martha Clare Morris
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, Ill 60612, USA
    Arch Neurol 62:1849-53. 2005
  7. pmc Perceived discrimination and mortality in a population-based study of older adults
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1038, Chicago, IL 60612, USA
    Am J Public Health 98:1241-7. 2008
  8. pmc Biracial population study of mortality in mild cognitive impairment and Alzheimer disease
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina Ave, Ste 1038, Chicago, IL 60612, USA
    Arch Neurol 66:767-72. 2009
  9. ncbi request reprint Parkinsonian signs and functional disability in old age
    Debra A Fleischman
    Rush Alzheimer s Disease Center and Departments of Neurological Sciences and Behavioral Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Exp Aging Res 33:59-76. 2007
  10. ncbi request reprint The relation of cigarette smoking to incident Alzheimer's disease in a biracial urban community population
    Neelum T Aggarwal
    Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Center, Chicago, IL 60612, USA
    Neuroepidemiology 26:140-6. 2006

Detail Information

Publications83

  1. ncbi request reprint Design of the Chicago Health and Aging Project (CHAP)
    Julia L Bienias
    Rush Institute for Healthy Aging, Rush University, Chicago, IL 60612, USA
    J Alzheimers Dis 5:349-55. 2003
    ..The results from these waves must be combined for effective analysis of the relation among risk factors and incident disease...
  2. pmc Race differences in emotional adaptation of family caregivers
    Kimberly A Skarupski
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612 3227, USA
    Aging Ment Health 13:715-24. 2009
    ..We hypothesized that black caregivers would exhibit lower levels of negative emotion and higher levels of positive emotion over time than whites...
  3. pmc Hostility and change in cognitive function over time in older blacks and whites
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    Psychosom Med 71:652-8. 2009
    ..To test whether the level of hostility predicted the rate of cognitive decline in a community of older blacks and whites and whether the association varied as a function of race...
  4. ncbi request reprint Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Chicago, IL 60612, USA
    Arch Gen Psychiatry 64:1204-12. 2007
    ..The personality trait of conscientiousness has been related to morbidity and mortality in old age, but its association with the development of Alzheimer disease is not known...
  5. ncbi request reprint Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change
    Martha Clare Morris
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Clin Nutr 81:508-14. 2005
    ..High intake of vitamin E from food (tocopherol), but not from supplements (which usually contain alpha-tocopherol), is inversely associated with Alzheimer disease...
  6. ncbi request reprint Fish consumption and cognitive decline with age in a large community study
    Martha Clare Morris
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, Ill 60612, USA
    Arch Neurol 62:1849-53. 2005
    ..Dietary intake of fish and the omega-3 fatty acids have been associated with lower risk of Alzheimer disease and stroke...
  7. pmc Perceived discrimination and mortality in a population-based study of older adults
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1038, Chicago, IL 60612, USA
    Am J Public Health 98:1241-7. 2008
    ..We examined the relation of individual-level perceived discrimination to mortality in a biracial, population-based sample...
  8. pmc Biracial population study of mortality in mild cognitive impairment and Alzheimer disease
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina Ave, Ste 1038, Chicago, IL 60612, USA
    Arch Neurol 66:767-72. 2009
    ..To assess mortality associated with mild cognitive impairment (MCI) and Alzheimer disease (AD) among older African Americans and whites from an urban community...
  9. ncbi request reprint Parkinsonian signs and functional disability in old age
    Debra A Fleischman
    Rush Alzheimer s Disease Center and Departments of Neurological Sciences and Behavioral Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Exp Aging Res 33:59-76. 2007
    ....
  10. ncbi request reprint The relation of cigarette smoking to incident Alzheimer's disease in a biracial urban community population
    Neelum T Aggarwal
    Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Center, Chicago, IL 60612, USA
    Neuroepidemiology 26:140-6. 2006
    ....
  11. ncbi request reprint Sex differences in the clinical manifestations of Alzheimer disease pathology
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Arch Gen Psychiatry 62:685-91. 2005
    ....
  12. ncbi request reprint The apolipoprotein E epsilon4 allele and incident Alzheimer's disease in persons with mild cognitive impairment
    Neelum T Aggarwal
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612 3872, USA
    Neurocase 11:3-7. 2005
    ..02, 2.63). There was a marginally significant reduction in the effect of epsilon4 in older compared to younger participants (p=.053). The results suggest that possession of an epsilon4 allele does increase risk of AD in persons with MCI...
  13. pmc The association of magnetic resonance imaging measures with cognitive function in a biracial population sample
    Neelum T Aggarwal
    Rush Alzheimer s Disease Center, 600 S Paulina Ave, Ste 1038, Chicago, IL 60612, USA
    Arch Neurol 67:475-82. 2010
    ..White matter hyperintensity volume (WMHV), cerebral infarcts, and total brain volume (TBV) are associated with cognitive function, but few studies have examined these associations in the general population or whether they differ by race...
  14. ncbi request reprint Motor dysfunction in mild cognitive impairment and the risk of incident Alzheimer disease
    Neelum T Aggarwal
    Rush Alzheimer s Disease Center, Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
    Arch Neurol 63:1763-9. 2006
    ..Little is known about motor function in mild cognitive impairment (MCI) and its relation to the risk of Alzheimer disease (AD)...
  15. ncbi request reprint Correlates of life space in a volunteer cohort of older adults
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Exp Aging Res 33:77-93. 2007
    ..The results suggest that the range of environmental movement in older adults is a useful indicator of health in old age and may complement measures of disability...
  16. pmc Use of home-based formal services by adult day care clients with Alzheimer's disease
    Kimberly A Skarupski
    Rush Institute for Healthy Aging, 1645 W Jackson, Chicago, IL, USA
    Home Health Care Serv Q 27:217-39. 2008
    ..To explore the association between adult day care (ADC) attendance and utilization of home-based formal services among people with Alzheimer's Disease (AD)...
  17. pmc Upper and lower extremity motor performance and functional impairment in Alzheimer's disease
    Liesi E Hebert
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Alzheimers Dis Other Demen 25:425-31. 2010
    ..It is important to preserve motor performance in individuals with AD because it influences physical function throughout the course of the disease...
  18. ncbi request reprint Black-white differences in depressive symptoms among older adults over time
    Kimberly A Skarupski
    Rush Institute for Healthy Aging, 1645 W Jackson, Suite 675, Chicago, IL 60612 3227, USA
    J Gerontol B Psychol Sci Soc Sci 60:P136-42. 2005
    ..225, p < .001) but remained robust. The racial differences increased slightly over time. Our findings support heightened awareness of depression in older Black populations...
  19. ncbi request reprint Early and late life cognitive activity and cognitive systems in old age
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Center, 600 South Paulina, Suite 1038, Chicago, IL 60612, USA
    J Int Neuropsychol Soc 11:400-7. 2005
    ..The results suggest that past cognitive activity contributes to current cognition principally through its association with cognitive activity in old age...
  20. doi request reprint Change in direct measures of physical performance among persons with Alzheimer's disease
    Liesi E Hebert
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL, USA
    Aging Ment Health 12:729-34. 2008
    ..Measures of physical performance were used in intact and community populations. We examined upper and lower extremity physical performance tests among people with Alzheimer's disease...
  21. ncbi request reprint Relation of blood pressure to risk of incident Alzheimer's disease and change in global cognitive function in older persons
    Raj C Shah
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Neuroepidemiology 26:30-6. 2006
    ..To examine the relation of systolic and diastolic blood pressure to incident Alzheimer's disease (AD) and rate of cognitive change...
  22. pmc Social engagement and cognitive function in old age
    Kristin R Krueger
    Rush Alzheimer s Disease Center and Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, USA
    Exp Aging Res 35:45-60. 2009
    ..The results confirm that higher level of social engagement in old age is associated with better cognitive function but the association varies across domains of social engagement...
  23. ncbi request reprint Is lower cognitive function in one spouse associated with depressive symptoms in the other spouse?
    Kimberly A Skarupski
    Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson, Suite 675, Chicago, IL 60612 3227, USA
    Aging Ment Health 10:621-30. 2006
    ..Our findings suggest that husbands may be particularly psychologically vulnerable to the negative effects of their wives' cognitive impairment. This vulnerability may have a range of long-term health and caregiving implications...
  24. ncbi request reprint The Rush Memory and Aging Project: study design and baseline characteristics of the study cohort
    David A Bennett
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1028, Chicago, IL 60612, USA
    Neuroepidemiology 25:163-75. 2005
    ..Their mean age was 81 years, about a third had 12 or fewer years of education, a third were men, and about 10% were members of a racial or ethnic minority group. More than 950 already have completed their baseline clinical evaluation...
  25. ncbi request reprint Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older persons
    Martha Clare Morris
    Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Ill 60612, USA
    Arch Neurol 62:641-5. 2005
    ..Deficiencies in folate and vitamin B12 have been associated with neurodegenerative disease...
  26. pmc Dietary folate and vitamins B-12 and B-6 not associated with incident Alzheimer's disease
    Martha Clare Morris
    Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson 675, Chicago, IL 60612, USA
    J Alzheimers Dis 9:435-43. 2006
    ..It is currently not known whether dietary intakes of folate and vitamins B12 and B6, co-factors in the methylation of homocysteine, protect against Alzheimer's disease...
  27. ncbi request reprint Neuroticism, extraversion, and mortality in a defined population of older persons
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Psychosom Med 67:841-5. 2005
    ..The objective of this study was to test the association of the personality traits of neuroticism and extraversion with risk of death in old age...
  28. ncbi request reprint Incidence of Alzheimer disease in a biracial urban community: relation to apolipoprotein E allele status
    Denis A Evans
    Rush Institute on Healthy Aging, Chicago, IL, USA
    Arch Neurol 60:185-9. 2003
    ..Few studies compare Alzheimer disease (AD) incidence among black and white subjects...
  29. pmc Pulmonary function, muscle strength and mortality in old age
    A S Buchman
    Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, United States
    Mech Ageing Dev 129:625-31. 2008
    ..Overall, these findings suggest that pulmonary function may partially account for the association of muscle strength and mortality...
  30. pmc Repetition priming and change in functional ability in older persons without dementia
    Debra A Fleischman
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Neuropsychology 23:98-104. 2009
    ..The results are discussed in terms of a common biological substrate in the inferotemporal neocortex, supporting efficient processing of meaningful visual-perceptual experience and proficient performance of activities of daily living...
  31. ncbi request reprint Cognitive decline and survival in Alzheimer's disease
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Int J Geriatr Psychiatry 21:356-62. 2006
    ..To test the association of rate of cognitive decline, an indicator of the severity of the underlying disease process, with risk of death in Alzheimer's disease (AD)...
  32. ncbi request reprint Racial disparities in disability: recent evidence from self-reported and performance-based disability measures in a population-based study of older adults
    Carlos F Mendes de Leon
    Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
    J Gerontol B Psychol Sci Soc Sci 60:S263-71. 2005
    ..Although disability levels have been declining in older adults, there is little current information on racial differences in disability...
  33. pmc Anti-inflammatory agents and cognitive decline in a bi-racial population
    Francine Grodstein
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL, USA
    Neuroepidemiology 30:45-50. 2008
    ..no use: mean difference = 0.12; p trend = 0.03). Overall, we found no relation between regular aspirin use and cognitive decline, but long-term use of ibuprofen may be related to decreased rates of cognitive decline in older persons...
  34. ncbi request reprint Grip strength and the risk of incident Alzheimer's disease
    Aron S Buchman
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Neuroepidemiology 29:66-73. 2007
    ..Declining strength in old age is associated with an increased risk of AD...
  35. ncbi request reprint Physical activity is associated with incident disability in community-based older persons
    Patricia A Boyle
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Am Geriatr Soc 55:195-201. 2007
    ....
  36. ncbi request reprint Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons
    Julie A Schneider
    Rush Alzheimer s Disease Center and Rush Institute for Healthy Aging, Department of Neurological Sciences, Rush University Medical Center, 600 South Paulina Street, Chicago, IL 60612, USA
    Ann Neurol 62:59-66. 2007
    ..Examine the effects of subcortical infarcts with Alzheimer's disease (AD) pathology on dementia, episodic memory, and other cognitive abilities in older persons...
  37. ncbi request reprint Early life socioeconomic status and late life risk of Alzheimer's disease
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Neuroepidemiology 25:8-14. 2005
    ..The results suggest that early life socioeconomic level is related to level of cognition in late life but not to rate of cognitive decline or risk of AD...
  38. ncbi request reprint Predictors of depressive symptoms in persons with Alzheimer's disease
    David W Gilley
    Rush Institute for Healthy Aging and Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Gerontol B Psychol Sci Soc Sci 59:P75-83. 2004
    ..Depressive symptoms in Alzheimer's disease appear to follow a more predictable pattern of expression than previously described...
  39. ncbi request reprint Efficacy of behavioral interventions for dementia caregivers
    Carol J Farran
    Rush University Medical Center, Chicago, IL, USA
    West J Nurs Res 29:944-60. 2007
    ..These findings indicate that dementia caregivers exposed to agitated behaviors can benefit from psychosocial interventions, particularly those aimed at building behavioral management skills...
  40. pmc Visuoperceptual repetition priming and progression of parkinsonian signs in aging
    Debra A Fleischman
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL, USA
    Neurobiol Aging 30:441-9. 2009
    ..Reduced visuoperceptual priming in aging may be an early signal of vulnerability in a corticostrial circuit that contributes to sensorimotor integration...
  41. pmc Neighborhood social cohesion and disorder in relation to walking in community-dwelling older adults: a multilevel analysis
    Carlos F Mendes de Leon
    Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
    J Aging Health 21:155-71. 2009
    ..Promotion of walking behavior in older adults may require improvement of the safety and upkeep of the neighborhood environment...
  42. ncbi request reprint Association of fecal incontinence with physical disability and impaired cognitive function
    Carline R Quander
    Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA
    Am J Gastroenterol 101:2588-93. 2006
    ..In this study, we report on the association of fecal incontinence with physical disability and impaired cognitive function in a large bi-racial population of individuals aged 65 yr and older...
  43. ncbi request reprint Dietary copper and high saturated and trans fat intakes associated with cognitive decline
    Martha Clare Morris
    Department of Internal Medicine, Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson Street, Chicago, IL 60612, USA
    Arch Neurol 63:1085-8. 2006
    ..Evidence from prospective epidemiologic studies and animal models suggests that intakes of dietary fats and copper may be associated with neurodegenerative diseases...
  44. pmc Childhood adversity and psychosocial adjustment in old age
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Geriatr Psychiatry 14:307-15. 2006
    ..The objective of this study was to test the hypothesis that higher level of childhood adversity is associated with lower level of psychosocial adjustment in old age...
  45. ncbi request reprint Physical activity, cognitive activity, and cognitive decline in a biracial community population
    Maureen T Sturman
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
    Arch Neurol 62:1750-4. 2005
    ..Findings from studies investigating whether physical activity reduces the risk of cognitive decline in old age have been inconsistent...
  46. ncbi request reprint A longitudinal study of implicit and explicit memory in old persons
    Debra A Fleischman
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Psychol Aging 19:617-25. 2004
    ..Findings indicate that explicit memory and priming are dissociable on the basis of age-related change and that mildly reduced priming is not an inevitable consequence of growing older...
  47. ncbi request reprint Do depressive symptoms predict declines in physical performance in an elderly, biracial population?
    Susan A Everson-Rose
    Rush Institute for Healthy Aging, Rush University Medical Center, Department of Preventive Medicine, Chicago, Illinois 60612, USA
    Psychosom Med 67:609-15. 2005
    ..We investigated whether depressive symptoms, assessed by the 10-item Center for Epidemiological Studies Depression Scale (CES-D), predicted change in physical function in elderly adults...
  48. ncbi request reprint Distress proneness and cognitive decline in a population of older persons
    Robert S Wilson
    Rush Alzheimer s Disease Center and Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Psychoneuroendocrinology 30:11-7. 2005
    ..059) after controlling for depressive symptoms. The results suggest that the tendency to experience psychological distress is associated with increased cognitive decline in old age...
  49. ncbi request reprint Personality and mortality in old age
    Robert S Wilson
    Rush Institute for Healthy Aging and Rush Alzheimer s Disease Center, Chicago, Illinois 60612, USA
    J Gerontol B Psychol Sci Soc Sci 59:P110-6. 2004
    ..Findings for extraversion were mixed, and neither agreeableness nor openness was strongly related to mortality. The results suggest that personality is associated with mortality in old age...
  50. doi request reprint Change in depressive symptoms during the prodromal phase of Alzheimer disease
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Ste 1038, Chicago, IL 60612, USA
    Arch Gen Psychiatry 65:439-45. 2008
    ..Prospective studies have established an association between depressive symptoms and risk of dementia, but how depressive symptoms change during the evolution of dementia is uncertain...
  51. ncbi request reprint Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease
    Martha Clare Morris
    Rush Institute for Healthy Aging, Department of Internal Medicine, Rush Alzheimer s Disease Center, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Arch Neurol 60:940-6. 2003
    ..Dietary n-3 polyunsaturated fatty acids improve brain functioning in animal studies, but there is limited study of whether this type of fat protects against Alzheimer disease...
  52. ncbi request reprint Implicit memory and Alzheimer's disease neuropathology
    Debra A Fleischman
    Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA
    Brain 128:2006-15. 2005
    ..The results suggest that hallmark indices of Alzheimer's disease neuropathology are associated with performance on priming tests to the extent that conceptual, but not perceptual, processing resources are required...
  53. ncbi request reprint Blood pressure and lower limb function in older persons
    Raj C Shah
    Department of Family Medicine, Rush Alzheimer s Disease Center, 710 South Paulina, Suite 8 North, Chicago, IL 60612, USA
    J Gerontol A Biol Sci Med Sci 61:839-43. 2006
    ..The purpose of this study was to examine the association of blood pressure (BP) with change in lower limb function in older persons...
  54. ncbi request reprint Reasonable estimates of serum vitamin E, vitamin C, and beta-cryptoxanthin are obtained with a food frequency questionnaire in older black and white adults
    Christy C Tangney
    Department of Clinical Nutrition, Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
    J Nutr 134:927-34. 2004
    ..These findings indicate that the modified Harvard FFQ provides reasonable estimates of serum levels of vitamin E, vitamin C and beta-cryptoxanthin among CHAP participants...
  55. ncbi request reprint Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function
    David A Bennett
    Rush Alzheimer s Disease Center and the Department of Neurological Sciences Rush University Medical Center, Chicago, IL 60612, USA
    Arch Neurol 61:378-84. 2004
    ..To test the hypothesis that the association of amyloid load with clinical Alzheimer disease (AD) and cognitive impairment is mediated through neurofibrillary tangles...
  56. ncbi request reprint Parkinsonianlike signs and risk of incident Alzheimer disease in older persons
    Robert S Wilson
    Rush Alzheimer s Disease Center and Rush Institute for Healthy Aging and the Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Arch Neurol 60:539-44. 2003
    ..Parkinsonianlike signs are common in older persons, but little is known about how their severity or rate of progression is related to the development of Alzheimer disease (AD) or decline in cognition...
  57. ncbi request reprint Validity and reproducibility of a food frequency questionnaire by cognition in an older biracial sample
    Martha Clare Morris
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Epidemiol 158:1213-7. 2003
    ..The modified Harvard SFFQ is a reasonable method of dietary assessment even in a population of older persons, some of whom are at advanced age, have chronic health conditions, and have cognitive impairment...
  58. ncbi request reprint Dietary fats and the risk of incident Alzheimer disease
    Martha Clare Morris
    Rush Institute for Healthy Aging, 1645 W Jackson, Suite 675, Chicago, IL 60612, USA
    Arch Neurol 60:194-200. 2003
    ..Few studies have investigated the effects of dietary fats on the development of Alzheimer disease. We examined the associations between intake of specific types of fat and incident Alzheimer disease in a biracial community study...
  59. ncbi request reprint Vitamin E and cognitive decline in older persons
    Martha Clare Morris
    Department of Preventive Medicine, Rush Institute for Healthy Aging, Rush Presbyterian St Luke s Medical Center, 1645 W Jackson, Suite 675, Chicago, IL 60612, USA
    Arch Neurol 59:1125-32. 2002
    ..Previous studies raise the possibility that antioxidants protect against neurodegenerative diseases...
  60. ncbi request reprint Caregiver psychological adjustment and institutionalization of persons with Alzheimer's disease
    David W Gilley
    Rush Institute for Healthy Aging, USA
    J Aging Health 17:172-89. 2005
    ..This prospective study examines the relationship between caregiver psychological adjustment and institutionalization of persons with Alzheimer's disease (AD)...
  61. ncbi request reprint Parkinsonian signs and cognitive function in old age
    Debra A Fleischman
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Int Neuropsychol Soc 11:591-7. 2005
    ..The results suggest that parkinsonian signs have a modest, but statistically reliable, association with level of cognitive function in old age...
  62. ncbi request reprint Cerebral infarctions and the relationship of depression symptoms to level of cognitive functioning in older persons
    David A Bennett
    Rush Alzheimer s Disease Center, Departments of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Geriatr Psychiatry 12:211-9. 2004
    ....
  63. ncbi request reprint Prevalence of and factors associated with fecal incontinence in a large community study of older individuals
    Carline R Quander
    Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, Illinois, USA
    Am J Gastroenterol 100:905-9. 2005
    ..In this study, we describe the prevalence of fecal incontinence by race, age, sex, the presence of major chronic conditions of stroke and diabetes, and the use of certain psychoactive medications...
  64. ncbi request reprint Caring for self while caring for others: the two-track life of coping with Alzheimer's disease
    Carol J Farran
    Rush University College of Nursing, Rush Institute for Healthy Aging, Chicago, Illinois 60612, USA
    J Gerontol Nurs 30:38-46. 2004
    ..Study findings suggest that nurses can play a pivotal role in intervening with family caregivers and potentially decreasing their depressive symptoms...
  65. ncbi request reprint Early life conditions and cognitive functioning in later life
    Susan A Everson-Rose
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Epidemiol 158:1083-9. 2003
    ..A better SEP and a more stimulating cognitive milieu in childhood have small but significant effects on absolute level of cognitive function; however, they do not seem to protect against cognitive decline in old age...
  66. ncbi request reprint Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study
    Martha Clare Morris
    Rush Institute for Healthy Aging, Rush Presbyterian St Luke s Medical Center, 1645 W Jackson, Suite 675, Chicago, IL 60612, USA
    JAMA 287:3230-7. 2002
    ..Oxidative processes have been suggested as elements in the development of Alzheimer disease (AD), but whether dietary intake of vitamin E and other antioxidant nutrients prevents its development is unknown...
  67. ncbi request reprint Participation in cognitively stimulating activities and risk of incident Alzheimer disease
    Robert S Wilson
    Rush Alzheimer s Disease Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
    JAMA 287:742-8. 2002
    ..Frequent participation in cognitively stimulating activities has been hypothesized to reduce risk of Alzheimer disease (AD), but prospective data regarding an association are lacking...
  68. ncbi request reprint Negative affect and mortality in older persons
    Robert S Wilson
    Rush Alzheimer s Disease Center and Rush Institute for Healthy Aging, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    Am J Epidemiol 158:827-35. 2003
    ..The results suggest that negative affect in older persons, especially internally experienced distress, is associated with an increased mortality risk...
  69. doi request reprint A hospitalist-run short-stay unit: features that predict length-of-stay and eventual admission to traditional inpatient services
    Brian P Lucas
    Division of Hospital Medicine, Department of Medicine, Stroger Hospital of Cook County and Rush Medical College, Chicago, Illinois, USA
    J Hosp Med 4:276-84. 2009
    ..Short-stay units (SSUs) provide an alternative to traditional inpatient services for patients with short anticipated hospital stays. Yet little is known about which patient types predict SSU success...
  70. pmc Predictors of beginning and ending caregiving during a 3-year period in a biracial community population of older adults
    Judith J McCann
    DNSc, Rush Institute for Healthy Aging, Rush University Medical Center, 1645 West Jackson Blvd, Suite 675, Chicago, IL 60612, USA
    Am J Public Health 94:1800-6. 2004
    ..We sought to identify predictors of beginning and ending caregiving...
  71. ncbi request reprint Black-white differences in health-related quality of life among older adults
    Kimberly A Skarupski
    Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson, Suite 675, Chicago, IL 60612 3227, USA
    Qual Life Res 16:287-96. 2007
    ..06; 95% CI: 0.89-1.27). Our results suggest that racial differences in HRQOL are associated with the combined effects of social disadvantage, poor physical health, and lower cognitive function...
  72. ncbi request reprint Physical activity and motor decline in older persons
    A S Buchman
    Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Facility, Suite 1038, 600 South Paulina Street, Chicago, Illinois 60612, USA
    Muscle Nerve 35:354-62. 2007
    ..Thus, higher levels of physical activity are associated with a slower rate of motor decline in older persons...
  73. ncbi request reprint Relative weight and mobility: a longitudinal study in a biracial population of older adults
    Carlos F Mendes de Leon
    Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA
    Ann Epidemiol 16:770-6. 2006
    ..We examined the association of relative weight with mobility and changes in mobility over time and whether these associations differed by race...
  74. ncbi request reprint Cognitive decline in old age: separating retest effects from the effects of growing older
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Psychol Aging 21:774-89. 2006
    ..Individual differences in retest effects were substantial but not consistent across cognitive measures. The results suggest that retest-based improvement in cognitive test performance can be substantial and persistent...
  75. ncbi request reprint Change in motor function and risk of mortality in older persons
    Aron S Buchman
    Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    J Am Geriatr Soc 55:11-9. 2007
    ..To assess the association between change in motor function and mortality...
  76. ncbi request reprint Terminal cognitive decline: accelerated loss of cognition in the last years of life
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, Suite 1038, Chicago, IL 60612, USA
    Psychosom Med 69:131-7. 2007
    ..To test the hypothesis that rate of cognitive decline accelerates in the last years of life...
  77. ncbi request reprint Racial differences in perceived discrimination in a community population of older blacks and whites
    Lisa L Barnes
    Rush Alzheimer s Disease Center and Institute for Healthy Aging
    J Aging Health 16:315-37. 2004
    ..To examine the prevalence of perceived discrimination in an older biracial population and to examine its correlation with depressive symptoms...
  78. ncbi request reprint Improved detection of substantia nigra pathology in Alzheimer's disease
    Julie A Schneider
    Rush Alzheimer s Disease Center, Rush University and Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
    J Histochem Cytochem 50:99-106. 2002
    ..We show that detection of nigra pathology is influenced by histological method. Clinicopathological studies using these methods are needed to determine the role of nigral pathology in AD...
  79. ncbi request reprint Changes in disability before and after myocardial infarction in older adults
    Carlos F Mendes de Leon
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
    Arch Intern Med 165:763-8. 2005
    ..Disability in older adults is thought to occur primarily as a consequence of clinical disease episodes. However, the temporal relationship between clinical disease and disability has received little systematic attention...
  80. ncbi request reprint Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's disease
    Thomas W Mitchell
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Ann Neurol 51:182-9. 2002
    ....
  81. pmc Levels of estrogen receptors alpha and beta in frontal cortex of patients with Alzheimer's disease: relationship to Mini-Mental State Examination scores
    Jeremiah F Kelly
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Curr Alzheimer Res 5:45-51. 2008
    ....
  82. ncbi request reprint A longitudinal study of black-white differences in social resources
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois, USA
    J Gerontol B Psychol Sci Soc Sci 59:S146-53. 2004
    ..This study examined the differences in levels of social networks and social engagement between older Blacks and Whites and racial differences in rates of change in social resources over time...
  83. ncbi request reprint Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment
    Hyman M Schipper
    Centre for Neurotranslational Research and Bloomfield Centre for Research in Aging, Lady Davis Institute, Sir Mortimer B Davis Jewish General Hospital, 3755 Cote St Catherine Road, Montreal, Que, Canada H3T 1E2
    Neurobiol Aging 27:252-61. 2006
    ..Cortical and hippocampal oxidative stress is a very early event in the pathogenesis of sporadic AD and correlates with the development of specific cognitive deficits in this condition...