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Species | Julia L BieniasSummaryAffiliation: Rush University Medical Center Country: USA Publications
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Publications
Design of the Chicago Health and Aging Project (CHAP)Julia L Bienias
Rush Institute for Healthy Aging, Rush University, Chicago, IL 60612, USA
J Alzheimers Dis 5:349-55. 2003..The results from these waves must be combined for effective analysis of the relation among risk factors and incident disease...
Race differences in emotional adaptation of family caregiversKimberly A Skarupski
Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612 3227, USA
Aging Ment Health 13:715-24. 2009..We hypothesized that black caregivers would exhibit lower levels of negative emotion and higher levels of positive emotion over time than whites...
Hostility and change in cognitive function over time in older blacks and whitesLisa L Barnes
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
Psychosom Med 71:652-8. 2009..To test whether the level of hostility predicted the rate of cognitive decline in a community of older blacks and whites and whether the association varied as a function of race...
Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairmentRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Chicago, IL 60612, USA
Arch Gen Psychiatry 64:1204-12. 2007..The personality trait of conscientiousness has been related to morbidity and mortality in old age, but its association with the development of Alzheimer disease is not known...
Relation of the tocopherol forms to incident Alzheimer disease and to cognitive changeMartha Clare Morris
Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
Am J Clin Nutr 81:508-14. 2005..High intake of vitamin E from food (tocopherol), but not from supplements (which usually contain alpha-tocopherol), is inversely associated with Alzheimer disease...
Fish consumption and cognitive decline with age in a large community studyMartha Clare Morris
Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, Ill 60612, USA
Arch Neurol 62:1849-53. 2005..Dietary intake of fish and the omega-3 fatty acids have been associated with lower risk of Alzheimer disease and stroke...
Perceived discrimination and mortality in a population-based study of older adultsLisa L Barnes
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1038, Chicago, IL 60612, USA
Am J Public Health 98:1241-7. 2008..We examined the relation of individual-level perceived discrimination to mortality in a biracial, population-based sample...
Biracial population study of mortality in mild cognitive impairment and Alzheimer diseaseRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina Ave, Ste 1038, Chicago, IL 60612, USA
Arch Neurol 66:767-72. 2009..To assess mortality associated with mild cognitive impairment (MCI) and Alzheimer disease (AD) among older African Americans and whites from an urban community...
Parkinsonian signs and functional disability in old ageDebra A Fleischman
Rush Alzheimer s Disease Center and Departments of Neurological Sciences and Behavioral Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
Exp Aging Res 33:59-76. 2007....
The relation of cigarette smoking to incident Alzheimer's disease in a biracial urban community populationNeelum T Aggarwal
Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Center, Chicago, IL 60612, USA
Neuroepidemiology 26:140-6. 2006....
Sex differences in the clinical manifestations of Alzheimer disease pathologyLisa L Barnes
Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
Arch Gen Psychiatry 62:685-91. 2005....
The apolipoprotein E epsilon4 allele and incident Alzheimer's disease in persons with mild cognitive impairmentNeelum T Aggarwal
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612 3872, USA
Neurocase 11:3-7. 2005..02, 2.63). There was a marginally significant reduction in the effect of epsilon4 in older compared to younger participants (p=.053). The results suggest that possession of an epsilon4 allele does increase risk of AD in persons with MCI...
The association of magnetic resonance imaging measures with cognitive function in a biracial population sampleNeelum T Aggarwal
Rush Alzheimer s Disease Center, 600 S Paulina Ave, Ste 1038, Chicago, IL 60612, USA
Arch Neurol 67:475-82. 2010..White matter hyperintensity volume (WMHV), cerebral infarcts, and total brain volume (TBV) are associated with cognitive function, but few studies have examined these associations in the general population or whether they differ by race...
Motor dysfunction in mild cognitive impairment and the risk of incident Alzheimer diseaseNeelum T Aggarwal
Rush Alzheimer s Disease Center, Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
Arch Neurol 63:1763-9. 2006..Little is known about motor function in mild cognitive impairment (MCI) and its relation to the risk of Alzheimer disease (AD)...
Correlates of life space in a volunteer cohort of older adultsLisa L Barnes
Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
Exp Aging Res 33:77-93. 2007..The results suggest that the range of environmental movement in older adults is a useful indicator of health in old age and may complement measures of disability...
Use of home-based formal services by adult day care clients with Alzheimer's diseaseKimberly A Skarupski
Rush Institute for Healthy Aging, 1645 W Jackson, Chicago, IL, USA
Home Health Care Serv Q 27:217-39. 2008..To explore the association between adult day care (ADC) attendance and utilization of home-based formal services among people with Alzheimer's Disease (AD)...
Upper and lower extremity motor performance and functional impairment in Alzheimer's diseaseLiesi E Hebert
Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
Am J Alzheimers Dis Other Demen 25:425-31. 2010..It is important to preserve motor performance in individuals with AD because it influences physical function throughout the course of the disease...
Black-white differences in depressive symptoms among older adults over timeKimberly A Skarupski
Rush Institute for Healthy Aging, 1645 W Jackson, Suite 675, Chicago, IL 60612 3227, USA
J Gerontol B Psychol Sci Soc Sci 60:P136-42. 2005..225, p < .001) but remained robust. The racial differences increased slightly over time. Our findings support heightened awareness of depression in older Black populations...
Early and late life cognitive activity and cognitive systems in old ageRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Center, 600 South Paulina, Suite 1038, Chicago, IL 60612, USA
J Int Neuropsychol Soc 11:400-7. 2005..The results suggest that past cognitive activity contributes to current cognition principally through its association with cognitive activity in old age...
Change in direct measures of physical performance among persons with Alzheimer's diseaseLiesi E Hebert
Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL, USA
Aging Ment Health 12:729-34. 2008..Measures of physical performance were used in intact and community populations. We examined upper and lower extremity physical performance tests among people with Alzheimer's disease...
Relation of blood pressure to risk of incident Alzheimer's disease and change in global cognitive function in older personsRaj C Shah
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Neuroepidemiology 26:30-6. 2006..To examine the relation of systolic and diastolic blood pressure to incident Alzheimer's disease (AD) and rate of cognitive change...
Social engagement and cognitive function in old ageKristin R Krueger
Rush Alzheimer s Disease Center and Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, USA
Exp Aging Res 35:45-60. 2009..The results confirm that higher level of social engagement in old age is associated with better cognitive function but the association varies across domains of social engagement...
Is lower cognitive function in one spouse associated with depressive symptoms in the other spouse?Kimberly A Skarupski
Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson, Suite 675, Chicago, IL 60612 3227, USA
Aging Ment Health 10:621-30. 2006..Our findings suggest that husbands may be particularly psychologically vulnerable to the negative effects of their wives' cognitive impairment. This vulnerability may have a range of long-term health and caregiving implications...
The Rush Memory and Aging Project: study design and baseline characteristics of the study cohortDavid A Bennett
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1028, Chicago, IL 60612, USA
Neuroepidemiology 25:163-75. 2005..Their mean age was 81 years, about a third had 12 or fewer years of education, a third were men, and about 10% were members of a racial or ethnic minority group. More than 950 already have completed their baseline clinical evaluation...
Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older personsMartha Clare Morris
Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Ill 60612, USA
Arch Neurol 62:641-5. 2005..Deficiencies in folate and vitamin B12 have been associated with neurodegenerative disease...
Dietary folate and vitamins B-12 and B-6 not associated with incident Alzheimer's diseaseMartha Clare Morris
Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson 675, Chicago, IL 60612, USA
J Alzheimers Dis 9:435-43. 2006..It is currently not known whether dietary intakes of folate and vitamins B12 and B6, co-factors in the methylation of homocysteine, protect against Alzheimer's disease...
Neuroticism, extraversion, and mortality in a defined population of older personsRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Psychosom Med 67:841-5. 2005..The objective of this study was to test the association of the personality traits of neuroticism and extraversion with risk of death in old age...
Incidence of Alzheimer disease in a biracial urban community: relation to apolipoprotein E allele statusDenis A Evans
Rush Institute on Healthy Aging, Chicago, IL, USA
Arch Neurol 60:185-9. 2003..Few studies compare Alzheimer disease (AD) incidence among black and white subjects...
Pulmonary function, muscle strength and mortality in old ageA S Buchman
Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, United States
Mech Ageing Dev 129:625-31. 2008..Overall, these findings suggest that pulmonary function may partially account for the association of muscle strength and mortality...
Repetition priming and change in functional ability in older persons without dementiaDebra A Fleischman
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Neuropsychology 23:98-104. 2009..The results are discussed in terms of a common biological substrate in the inferotemporal neocortex, supporting efficient processing of meaningful visual-perceptual experience and proficient performance of activities of daily living...
Cognitive decline and survival in Alzheimer's diseaseRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Int J Geriatr Psychiatry 21:356-62. 2006..To test the association of rate of cognitive decline, an indicator of the severity of the underlying disease process, with risk of death in Alzheimer's disease (AD)...
Racial disparities in disability: recent evidence from self-reported and performance-based disability measures in a population-based study of older adultsCarlos F Mendes de Leon
Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
J Gerontol B Psychol Sci Soc Sci 60:S263-71. 2005..Although disability levels have been declining in older adults, there is little current information on racial differences in disability...
Anti-inflammatory agents and cognitive decline in a bi-racial populationFrancine Grodstein
Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL, USA
Neuroepidemiology 30:45-50. 2008..no use: mean difference = 0.12; p trend = 0.03). Overall, we found no relation between regular aspirin use and cognitive decline, but long-term use of ibuprofen may be related to decreased rates of cognitive decline in older persons...
Grip strength and the risk of incident Alzheimer's diseaseAron S Buchman
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Neuroepidemiology 29:66-73. 2007..Declining strength in old age is associated with an increased risk of AD...
Physical activity is associated with incident disability in community-based older personsPatricia A Boyle
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
J Am Geriatr Soc 55:195-201. 2007....
Subcortical infarcts, Alzheimer's disease pathology, and memory function in older personsJulie A Schneider
Rush Alzheimer s Disease Center and Rush Institute for Healthy Aging, Department of Neurological Sciences, Rush University Medical Center, 600 South Paulina Street, Chicago, IL 60612, USA
Ann Neurol 62:59-66. 2007..Examine the effects of subcortical infarcts with Alzheimer's disease (AD) pathology on dementia, episodic memory, and other cognitive abilities in older persons...
Early life socioeconomic status and late life risk of Alzheimer's diseaseRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Neuroepidemiology 25:8-14. 2005..The results suggest that early life socioeconomic level is related to level of cognition in late life but not to rate of cognitive decline or risk of AD...
Predictors of depressive symptoms in persons with Alzheimer's diseaseDavid W Gilley
Rush Institute for Healthy Aging and Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
J Gerontol B Psychol Sci Soc Sci 59:P75-83. 2004..Depressive symptoms in Alzheimer's disease appear to follow a more predictable pattern of expression than previously described...
Efficacy of behavioral interventions for dementia caregiversCarol J Farran
Rush University Medical Center, Chicago, IL, USA
West J Nurs Res 29:944-60. 2007..These findings indicate that dementia caregivers exposed to agitated behaviors can benefit from psychosocial interventions, particularly those aimed at building behavioral management skills...
Visuoperceptual repetition priming and progression of parkinsonian signs in agingDebra A Fleischman
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL, USA
Neurobiol Aging 30:441-9. 2009..Reduced visuoperceptual priming in aging may be an early signal of vulnerability in a corticostrial circuit that contributes to sensorimotor integration...
Neighborhood social cohesion and disorder in relation to walking in community-dwelling older adults: a multilevel analysisCarlos F Mendes de Leon
Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
J Aging Health 21:155-71. 2009..Promotion of walking behavior in older adults may require improvement of the safety and upkeep of the neighborhood environment...
Association of fecal incontinence with physical disability and impaired cognitive functionCarline R Quander
Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA
Am J Gastroenterol 101:2588-93. 2006..In this study, we report on the association of fecal incontinence with physical disability and impaired cognitive function in a large bi-racial population of individuals aged 65 yr and older...
Dietary copper and high saturated and trans fat intakes associated with cognitive declineMartha Clare Morris
Department of Internal Medicine, Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson Street, Chicago, IL 60612, USA
Arch Neurol 63:1085-8. 2006..Evidence from prospective epidemiologic studies and animal models suggests that intakes of dietary fats and copper may be associated with neurodegenerative diseases...
Childhood adversity and psychosocial adjustment in old ageRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Am J Geriatr Psychiatry 14:307-15. 2006..The objective of this study was to test the hypothesis that higher level of childhood adversity is associated with lower level of psychosocial adjustment in old age...
Physical activity, cognitive activity, and cognitive decline in a biracial community populationMaureen T Sturman
Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
Arch Neurol 62:1750-4. 2005..Findings from studies investigating whether physical activity reduces the risk of cognitive decline in old age have been inconsistent...
A longitudinal study of implicit and explicit memory in old personsDebra A Fleischman
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Psychol Aging 19:617-25. 2004..Findings indicate that explicit memory and priming are dissociable on the basis of age-related change and that mildly reduced priming is not an inevitable consequence of growing older...
Do depressive symptoms predict declines in physical performance in an elderly, biracial population?Susan A Everson-Rose
Rush Institute for Healthy Aging, Rush University Medical Center, Department of Preventive Medicine, Chicago, Illinois 60612, USA
Psychosom Med 67:609-15. 2005..We investigated whether depressive symptoms, assessed by the 10-item Center for Epidemiological Studies Depression Scale (CES-D), predicted change in physical function in elderly adults...
Distress proneness and cognitive decline in a population of older personsRobert S Wilson
Rush Alzheimer s Disease Center and Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
Psychoneuroendocrinology 30:11-7. 2005..059) after controlling for depressive symptoms. The results suggest that the tendency to experience psychological distress is associated with increased cognitive decline in old age...
Personality and mortality in old ageRobert S Wilson
Rush Institute for Healthy Aging and Rush Alzheimer s Disease Center, Chicago, Illinois 60612, USA
J Gerontol B Psychol Sci Soc Sci 59:P110-6. 2004..Findings for extraversion were mixed, and neither agreeableness nor openness was strongly related to mortality. The results suggest that personality is associated with mortality in old age...
Change in depressive symptoms during the prodromal phase of Alzheimer diseaseRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Ste 1038, Chicago, IL 60612, USA
Arch Gen Psychiatry 65:439-45. 2008..Prospective studies have established an association between depressive symptoms and risk of dementia, but how depressive symptoms change during the evolution of dementia is uncertain...
Consumption of fish and n-3 fatty acids and risk of incident Alzheimer diseaseMartha Clare Morris
Rush Institute for Healthy Aging, Department of Internal Medicine, Rush Alzheimer s Disease Center, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
Arch Neurol 60:940-6. 2003..Dietary n-3 polyunsaturated fatty acids improve brain functioning in animal studies, but there is limited study of whether this type of fat protects against Alzheimer disease...
Implicit memory and Alzheimer's disease neuropathologyDebra A Fleischman
Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA
Brain 128:2006-15. 2005..The results suggest that hallmark indices of Alzheimer's disease neuropathology are associated with performance on priming tests to the extent that conceptual, but not perceptual, processing resources are required...
Blood pressure and lower limb function in older personsRaj C Shah
Department of Family Medicine, Rush Alzheimer s Disease Center, 710 South Paulina, Suite 8 North, Chicago, IL 60612, USA
J Gerontol A Biol Sci Med Sci 61:839-43. 2006..The purpose of this study was to examine the association of blood pressure (BP) with change in lower limb function in older persons...
Reasonable estimates of serum vitamin E, vitamin C, and beta-cryptoxanthin are obtained with a food frequency questionnaire in older black and white adultsChristy C Tangney
Department of Clinical Nutrition, Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
J Nutr 134:927-34. 2004..These findings indicate that the modified Harvard FFQ provides reasonable estimates of serum levels of vitamin E, vitamin C and beta-cryptoxanthin among CHAP participants...
Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive functionDavid A Bennett
Rush Alzheimer s Disease Center and the Department of Neurological Sciences Rush University Medical Center, Chicago, IL 60612, USA
Arch Neurol 61:378-84. 2004..To test the hypothesis that the association of amyloid load with clinical Alzheimer disease (AD) and cognitive impairment is mediated through neurofibrillary tangles...
Parkinsonianlike signs and risk of incident Alzheimer disease in older personsRobert S Wilson
Rush Alzheimer s Disease Center and Rush Institute for Healthy Aging and the Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
Arch Neurol 60:539-44. 2003..Parkinsonianlike signs are common in older persons, but little is known about how their severity or rate of progression is related to the development of Alzheimer disease (AD) or decline in cognition...
Validity and reproducibility of a food frequency questionnaire by cognition in an older biracial sampleMartha Clare Morris
Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
Am J Epidemiol 158:1213-7. 2003..The modified Harvard SFFQ is a reasonable method of dietary assessment even in a population of older persons, some of whom are at advanced age, have chronic health conditions, and have cognitive impairment...
Dietary fats and the risk of incident Alzheimer diseaseMartha Clare Morris
Rush Institute for Healthy Aging, 1645 W Jackson, Suite 675, Chicago, IL 60612, USA
Arch Neurol 60:194-200. 2003..Few studies have investigated the effects of dietary fats on the development of Alzheimer disease. We examined the associations between intake of specific types of fat and incident Alzheimer disease in a biracial community study...
Vitamin E and cognitive decline in older personsMartha Clare Morris
Department of Preventive Medicine, Rush Institute for Healthy Aging, Rush Presbyterian St Luke s Medical Center, 1645 W Jackson, Suite 675, Chicago, IL 60612, USA
Arch Neurol 59:1125-32. 2002..Previous studies raise the possibility that antioxidants protect against neurodegenerative diseases...
Caregiver psychological adjustment and institutionalization of persons with Alzheimer's diseaseDavid W Gilley
Rush Institute for Healthy Aging, USA
J Aging Health 17:172-89. 2005..DISCUSSION: The findings highlight the importance of caregiver appraisals in decisions to institutionalize persons with a dementia syndrome, but the limited impact of caregiver emotion was unexpected and requires further study...
Parkinsonian signs and cognitive function in old ageDebra A Fleischman
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
J Int Neuropsychol Soc 11:591-7. 2005..The results suggest that parkinsonian signs have a modest, but statistically reliable, association with level of cognitive function in old age...
Cerebral infarctions and the relationship of depression symptoms to level of cognitive functioning in older personsDavid A Bennett
Rush Alzheimer s Disease Center, Departments of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
Am J Geriatr Psychiatry 12:211-9. 2004....
Prevalence of and factors associated with fecal incontinence in a large community study of older individualsCarline R Quander
Department of Internal Medicine, Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, Illinois, USA
Am J Gastroenterol 100:905-9. 2005..In this study, we describe the prevalence of fecal incontinence by race, age, sex, the presence of major chronic conditions of stroke and diabetes, and the use of certain psychoactive medications...
Caring for self while caring for others: the two-track life of coping with Alzheimer's diseaseCarol J Farran
Rush University College of Nursing, Rush Institute for Healthy Aging, Chicago, Illinois 60612, USA
J Gerontol Nurs 30:38-46. 2004..Study findings suggest that nurses can play a pivotal role in intervening with family caregivers and potentially decreasing their depressive symptoms...
Early life conditions and cognitive functioning in later lifeSusan A Everson-Rose
Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
Am J Epidemiol 158:1083-9. 2003..A better SEP and a more stimulating cognitive milieu in childhood have small but significant effects on absolute level of cognitive function; however, they do not seem to protect against cognitive decline in old age...
Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community studyMartha Clare Morris
Rush Institute for Healthy Aging, Rush Presbyterian St Luke s Medical Center, 1645 W Jackson, Suite 675, Chicago, IL 60612, USA
JAMA 287:3230-7. 2002..Oxidative processes have been suggested as elements in the development of Alzheimer disease (AD), but whether dietary intake of vitamin E and other antioxidant nutrients prevents its development is unknown...
Participation in cognitively stimulating activities and risk of incident Alzheimer diseaseRobert S Wilson
Rush Alzheimer s Disease Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
JAMA 287:742-8. 2002..Frequent participation in cognitively stimulating activities has been hypothesized to reduce risk of Alzheimer disease (AD), but prospective data regarding an association are lacking...
Negative affect and mortality in older personsRobert S Wilson
Rush Alzheimer s Disease Center and Rush Institute for Healthy Aging, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
Am J Epidemiol 158:827-35. 2003..The results suggest that negative affect in older persons, especially internally experienced distress, is associated with an increased mortality risk...
A hospitalist-run short-stay unit: features that predict length-of-stay and eventual admission to traditional inpatient servicesBrian P Lucas
Division of Hospital Medicine, Department of Medicine, Stroger Hospital of Cook County and Rush Medical College, Chicago, Illinois, USA
J Hosp Med 4:276-84. 2009..Short-stay units (SSUs) provide an alternative to traditional inpatient services for patients with short anticipated hospital stays. Yet little is known about which patient types predict SSU success...
Predictors of beginning and ending caregiving during a 3-year period in a biracial community population of older adultsJudith J McCann
DNSc, Rush Institute for Healthy Aging, Rush University Medical Center, 1645 West Jackson Blvd, Suite 675, Chicago, IL 60612, USA
Am J Public Health 94:1800-6. 2004..We sought to identify predictors of beginning and ending caregiving...
Black-white differences in health-related quality of life among older adultsKimberly A Skarupski
Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson, Suite 675, Chicago, IL 60612 3227, USA
Qual Life Res 16:287-96. 2007..06; 95% CI: 0.89-1.27). Our results suggest that racial differences in HRQOL are associated with the combined effects of social disadvantage, poor physical health, and lower cognitive function...
Physical activity and motor decline in older personsA S Buchman
Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Facility, Suite 1038, 600 South Paulina Street, Chicago, Illinois 60612, USA
Muscle Nerve 35:354-62. 2007..Thus, higher levels of physical activity are associated with a slower rate of motor decline in older persons...
Relative weight and mobility: a longitudinal study in a biracial population of older adultsCarlos F Mendes de Leon
Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA
Ann Epidemiol 16:770-6. 2006..We examined the association of relative weight with mobility and changes in mobility over time and whether these associations differed by race...
Cognitive decline in old age: separating retest effects from the effects of growing olderRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Psychol Aging 21:774-89. 2006..Individual differences in retest effects were substantial but not consistent across cognitive measures. The results suggest that retest-based improvement in cognitive test performance can be substantial and persistent...
Change in motor function and risk of mortality in older personsAron S Buchman
Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
J Am Geriatr Soc 55:11-9. 2007..To assess the association between change in motor function and mortality...
Terminal cognitive decline: accelerated loss of cognition in the last years of lifeRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, Suite 1038, Chicago, IL 60612, USA
Psychosom Med 69:131-7. 2007..To test the hypothesis that rate of cognitive decline accelerates in the last years of life...
Racial differences in perceived discrimination in a community population of older blacks and whitesLisa L Barnes
Rush Alzheimer s Disease Center and Institute for Healthy Aging
J Aging Health 16:315-37. 2004..To examine the prevalence of perceived discrimination in an older biracial population and to examine its correlation with depressive symptoms...
Improved detection of substantia nigra pathology in Alzheimer's diseaseJulie A Schneider
Rush Alzheimer s Disease Center, Rush University and Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
J Histochem Cytochem 50:99-106. 2002..We show that detection of nigra pathology is influenced by histological method. Clinicopathological studies using these methods are needed to determine the role of nigral pathology in AD...
Changes in disability before and after myocardial infarction in older adultsCarlos F Mendes de Leon
Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
Arch Intern Med 165:763-8. 2005..Disability in older adults is thought to occur primarily as a consequence of clinical disease episodes. However, the temporal relationship between clinical disease and disability has received little systematic attention...
Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's diseaseThomas W Mitchell
Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Ann Neurol 51:182-9. 2002....
Levels of estrogen receptors alpha and beta in frontal cortex of patients with Alzheimer's disease: relationship to Mini-Mental State Examination scoresJeremiah F Kelly
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Curr Alzheimer Res 5:45-51. 2008....
A longitudinal study of black-white differences in social resourcesLisa L Barnes
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois, USA
J Gerontol B Psychol Sci Soc Sci 59:S146-53. 2004..This study examined the differences in levels of social networks and social engagement between older Blacks and Whites and racial differences in rates of change in social resources over time...
Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairmentHyman M Schipper
Centre for Neurotranslational Research and Bloomfield Centre for Research in Aging, Lady Davis Institute, Sir Mortimer B Davis Jewish General Hospital, 3755 Cote St Catherine Road, Montreal, Que, Canada H3T 1E2
Neurobiol Aging 27:252-61. 2006..Cortical and hippocampal oxidative stress is a very early event in the pathogenesis of sporadic AD and correlates with the development of specific cognitive deficits in this condition...
