Research Topics
Species | Lisa L BarnesSummaryAffiliation: Rush University Medical Center Country: USA Publications
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Publications
Effects of early-life adversity on cognitive decline in older African Americans and whitesLisa L Barnes
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL, USA
Neurology 79:2321-7. 2012..Early-life adversity is related to adult health in old age but little is known about its relation with cognitive decline...
The Minority Aging Research Study: ongoing efforts to obtain brain donation in African Americans without dementiaLisa L Barnes
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1038, Chicago, IL 60612, USA
Curr Alzheimer Res 9:734-45. 2012..The implications of these efforts are discussed...
Correlates of life space in a volunteer cohort of older adultsLisa L Barnes
Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
Exp Aging Res 33:77-93. 2007..The results suggest that the range of environmental movement in older adults is a useful indicator of health in old age and may complement measures of disability...
A longitudinal study of black-white differences in social resourcesLisa L Barnes
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois, USA
J Gerontol B Psychol Sci Soc Sci 59:S146-53. 2004..This study examined the differences in levels of social networks and social engagement between older Blacks and Whites and racial differences in rates of change in social resources over time...
Racial differences in perceived discrimination in a community population of older blacks and whitesLisa L Barnes
Rush Alzheimer s Disease Center and Institute for Healthy Aging
J Aging Health 16:315-37. 2004..To examine the prevalence of perceived discrimination in an older biracial population and to examine its correlation with depressive symptoms...
The relation of lifetime cognitive activity and lifetime access to resources to late-life cognitive function in older African AmericansLisa L Barnes
Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 13:516-28. 2006..The results suggest that both measures are psychometrically sound in a minority population and that lifetime cognitive activity may contribute to current cognitive function in African Americans...
Sex differences in the clinical manifestations of Alzheimer disease pathologyLisa L Barnes
Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
Arch Gen Psychiatry 62:685-91. 2005....
Hostility and change in cognitive function over time in older blacks and whitesLisa L Barnes
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
Psychosom Med 71:652-8. 2009..To test whether the level of hostility predicted the rate of cognitive decline in a community of older blacks and whites and whether the association varied as a function of race...
Effect of a purpose in life on risk of incident Alzheimer disease and mild cognitive impairment in community-dwelling older personsPatricia A Boyle
Rush Alzheimer s Disease Center, 600 S Paulina, Ste 1020B, Chicago, IL 60612, USA
Arch Gen Psychiatry 67:304-10. 2010..Emerging data suggest that psychological and experiential factors are associated with risk of Alzheimer disease (AD), but the association of purpose in life with incident AD is unknown...
Perceived discrimination and mortality in a population-based study of older adultsLisa L Barnes
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1038, Chicago, IL 60612, USA
Am J Public Health 98:1241-7. 2008..We examined the relation of individual-level perceived discrimination to mortality in a biracial, population-based sample...
Racial differences in the progression of cognitive decline in Alzheimer diseaseLisa L Barnes
Rush Alzheimer s Disease Center, Depeartment of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
Am J Geriatr Psychiatry 13:959-67. 2005..The purpose of the current study was to examine the association of race with rate of cognitive decline in AD...
Biracial population study of mortality in mild cognitive impairment and Alzheimer diseaseRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina Ave, Ste 1038, Chicago, IL 60612, USA
Arch Neurol 66:767-72. 2009..To assess mortality associated with mild cognitive impairment (MCI) and Alzheimer disease (AD) among older African Americans and whites from an urban community...
Black-white differences in depressive symptoms among older adults over timeKimberly A Skarupski
Rush Institute for Healthy Aging, 1645 W Jackson, Suite 675, Chicago, IL 60612 3227, USA
J Gerontol B Psychol Sci Soc Sci 60:P136-42. 2005..225, p < .001) but remained robust. The racial differences increased slightly over time. Our findings support heightened awareness of depression in older Black populations...
Overview and findings from the rush Memory and Aging ProjectDavid A Bennett
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1028, Chicago, IL 60612, USA
Curr Alzheimer Res 9:646-63. 2012..The findings are discussed and contextualized...
Neighborhood-level cohesion and disorder: measurement and validation in two older adult urban populationsKathleen A Cagney
Department of Health Studies, The University of Chicago, 5841 South Maryland Avenue, MC 2007, Chicago, IL 60637, USA
J Gerontol B Psychol Sci Soc Sci 64:415-24. 2009..Drawing from collective efficacy and social disorganization theories, we developed and validated measures of neighborhood-level social processes...
Social engagement and cognitive function in old ageKristin R Krueger
Rush Alzheimer s Disease Center and Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, USA
Exp Aging Res 35:45-60. 2009..The results confirm that higher level of social engagement in old age is associated with better cognitive function but the association varies across domains of social engagement...
Cognitive decline and survival in Alzheimer's diseaseRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Int J Geriatr Psychiatry 21:356-62. 2006..To test the association of rate of cognitive decline, an indicator of the severity of the underlying disease process, with risk of death in Alzheimer's disease (AD)...
Early and late life cognitive activity and cognitive systems in old ageRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Center, 600 South Paulina, Suite 1038, Chicago, IL 60612, USA
J Int Neuropsychol Soc 11:400-7. 2005..The results suggest that past cognitive activity contributes to current cognition principally through its association with cognitive activity in old age...
The apolipoprotein E epsilon 4 allele and decline in different cognitive systems during a 6-year periodRobert S Wilson
Rush Alzheimer s Disease Center and Rush Institute for Healthy Aging, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
Arch Neurol 59:1154-60. 2002..The apolipoprotein E (APOE) epsilon 4 allele is known to influence risk of AD but it has been difficult to establish whether it affects episodic memory differently from other cognitive functions...
Change in cognitive function in Alzheimer's disease in African-American and white personsLisa L Barnes
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Neuroepidemiology 26:16-22. 2006..06), perceptual speed (p = 0.07) and naming (p = 0.08). The results suggest that the rate of cognitive decline in AD is slower in African-Americans compared with whites, particularly for episodic memory...
Loneliness and risk of Alzheimer diseaseRobert S Wilson
Rush Alzheimer s Disease Center, Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
Arch Gen Psychiatry 64:234-40. 2007..Social isolation in old age has been associated with risk of developing dementia, but the risk associated with perceived isolation, or loneliness, is not well understood...
Cognitive function is associated with the development of mobility impairments in community-dwelling eldersAron S Buchman
Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
Am J Geriatr Psychiatry 19:571-80. 2011..To examine the association of cognitive function with the risk of incident mobility impairments and the rate of declining mobility in older adults...
Racial differences in the association of education with physical and cognitive function in older blacks and whitesLisa L Barnes
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 South Paulina, Suite 1038, Chicago, IL 60612, USA
J Gerontol B Psychol Sci Soc Sci 66:354-63. 2011..We examined racial differences in the cross-sectional association of education with physical and cognitive function performance in older adults...
Participation in cognitively stimulating activities and risk of incident Alzheimer diseaseRobert S Wilson
Rush Alzheimer s Disease Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
JAMA 287:742-8. 2002..Frequent participation in cognitively stimulating activities has been hypothesized to reduce risk of Alzheimer disease (AD), but prospective data regarding an association are lacking...
Late-life social activity and cognitive decline in old ageBryan D James
Rush Alzheimer s Disease Center, Chicago, Illinois 60612, USA
J Int Neuropsychol Soc 17:998-1005. 2011..These results confirm that more socially active older adults experience less cognitive decline in old age...
Life space and risk of Alzheimer disease, mild cognitive impairment, and cognitive decline in old ageBryan D James
Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA
Am J Geriatr Psychiatry 19:961-9. 2011....
Racial disparities in disability: recent evidence from self-reported and performance-based disability measures in a population-based study of older adultsCarlos F Mendes de Leon
Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
J Gerontol B Psychol Sci Soc Sci 60:S263-71. 2005..Although disability levels have been declining in older adults, there is little current information on racial differences in disability...
Neighborhood social cohesion and disorder in relation to walking in community-dwelling older adults: a multilevel analysisCarlos F Mendes de Leon
Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
J Aging Health 21:155-71. 2009..Promotion of walking behavior in older adults may require improvement of the safety and upkeep of the neighborhood environment...
Microinfarct pathology, dementia, and cognitive systemsZoe Arvanitakis
Rush Alzheimer s Disease Center, 600 S Paulina, Suite 1020, Rush University Medical Center, Chicago, IL 60612, USA
Stroke 42:722-7. 2011..Little is known about the role of microinfarcts in dementia and cognition. We examined microinfarcts and dementia, global cognition, and 5 cognitive systems in community-dwelling older persons...
Recruitment and enrollment of caregivers for a lifestyle physical activity clinical trialCaryn D Etkin
College of Nursing, Rush University Medical Center, 600 S Paulina St, 1080 AAC, Chicago, IL 60612, USA
Res Nurs Health 35:70-81. 2012..We conclude that social marketing and community-based approaches provide a solid foundation for organizing recruitment activities for clinical trials with older adults...
Childhood adversity and psychosocial adjustment in old ageRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Am J Geriatr Psychiatry 14:307-15. 2006..The objective of this study was to test the hypothesis that higher level of childhood adversity is associated with lower level of psychosocial adjustment in old age...
Purpose in life is associated with mortality among community-dwelling older personsPatricia A Boyle
Rush Alzheimer s Disease Center, Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, USA
Psychosom Med 71:574-9. 2009..To assess the association between purpose in life and all-cause mortality in community-dwelling elderly persons...
Association between life space and risk of mortality in advanced agePatricia A Boyle
Rush Alzheimer s Disease Center, Chicago, Illinois 60612, USA
J Am Geriatr Soc 58:1925-30. 2010..To examine the association between life space, a measure of functional status that describes the range of movement through the environment covered during daily functioning, and the risk of mortality in older community-based persons...
Individual differences in rates of change in cognitive abilities of older personsRobert S Wilson
Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
Psychol Aging 17:179-93. 2002..The results suggest that change in cognitive function in old age primarily reflects person-specific factors rather than an inevitable developmental process...
Relation of driving status to incident life space constriction in community-dwelling older persons: a prospective cohort studyRaj C Shah
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 South Paulina, Suite 1022, Chicago, IL 60612, USA
J Gerontol A Biol Sci Med Sci 67:984-9. 2012..We examined whether being licensed to drive is associated with maintaining spatial movement in older persons initially reporting maximum spatial mobility...
Assessing family caregiver skill in managing behavioral symptoms of Alzheimer's diseaseCarol J Farran
Rush University College of Nursing, Rush University Medical Center, Chicago, IL, USA carol_
Aging Ment Health 15:510-21. 2011..This measurement study operationalized family caregiver skill in managing behavioral symptoms associated with Alzheimer's disease (AD) by testing a Caregiver Assessment of Behavioral Skill-Self-Report (CAB-SR) measure...
Medicare part D enrollment in a biracial community-based population of older adultsKimberly A Skarupski
Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612 3227, USA
Gerontologist 49:828-38. 2009..The Medicare Prescription Drug Benefit (Part D) program debuted in January 2006. We ascertained the sociodemographic and health characteristics of Blacks and Whites who enrolled in the early stages of the program...
Diabetes and cognitive systems in older black and white personsZoe Arvanitakis
Department of Neurological Sciences and Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA
Alzheimer Dis Assoc Disord 24:37-42. 2010..We found similar effects of diabetes on cognition in both racial groups. Because diabetes is twice as common in blacks, the burden of diabetes on cognition is higher in black than white persons...
Association between cognitive activity and cognitive function in older HispanicsMaria J Marquine
Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
J Int Neuropsychol Soc 18:1041-51. 2012..Thus, interventions aimed at increasing frequency of participation in cognitively stimulating activity may offer a potential target to reduce cognitive impairment in Hispanics...
Research Grants
- Risk Factors for Cognitive Decline in African AmericansLISA BARNES YOUNG; Fiscal Year: 2007..The faster growth of the aging minority population adds urgency to the need for a better understanding of risk factors related to cognitive decline. ..
- Risk Factors for Cognitive Decline in African-AmericansLisa L Barnes; Fiscal Year: 2010....
