Lisa L Barnes

Summary

Affiliation: Rush University Medical Center
Country: USA

Publications

  1. pmc Effects of early-life adversity on cognitive decline in older African Americans and whites
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL, USA
    Neurology 79:2321-7. 2012
  2. pmc The Minority Aging Research Study: ongoing efforts to obtain brain donation in African Americans without dementia
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1038, Chicago, IL 60612, USA
    Curr Alzheimer Res 9:734-45. 2012
  3. ncbi request reprint The relation of lifetime cognitive activity and lifetime access to resources to late-life cognitive function in older African Americans
    Lisa L Barnes
    Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 13:516-28. 2006
  4. ncbi request reprint Sex differences in the clinical manifestations of Alzheimer disease pathology
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Arch Gen Psychiatry 62:685-91. 2005
  5. ncbi request reprint Racial differences in perceived discrimination in a community population of older blacks and whites
    Lisa L Barnes
    Rush Alzheimer s Disease Center and Institute for Healthy Aging
    J Aging Health 16:315-37. 2004
  6. ncbi request reprint A longitudinal study of black-white differences in social resources
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois, USA
    J Gerontol B Psychol Sci Soc Sci 59:S146-53. 2004
  7. ncbi request reprint Correlates of life space in a volunteer cohort of older adults
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Exp Aging Res 33:77-93. 2007
  8. pmc Hostility and change in cognitive function over time in older blacks and whites
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    Psychosom Med 71:652-8. 2009
  9. pmc Effect of a purpose in life on risk of incident Alzheimer disease and mild cognitive impairment in community-dwelling older persons
    Patricia A Boyle
    Rush Alzheimer s Disease Center, 600 S Paulina, Ste 1020B, Chicago, IL 60612, USA
    Arch Gen Psychiatry 67:304-10. 2010
  10. pmc Perceived discrimination and mortality in a population-based study of older adults
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1038, Chicago, IL 60612, USA
    Am J Public Health 98:1241-7. 2008

Research Grants

Detail Information

Publications44

  1. pmc Effects of early-life adversity on cognitive decline in older African Americans and whites
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL, USA
    Neurology 79:2321-7. 2012
    ..Early-life adversity is related to adult health in old age but little is known about its relation with cognitive decline...
  2. pmc The Minority Aging Research Study: ongoing efforts to obtain brain donation in African Americans without dementia
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1038, Chicago, IL 60612, USA
    Curr Alzheimer Res 9:734-45. 2012
    ..The implications of these efforts are discussed...
  3. ncbi request reprint The relation of lifetime cognitive activity and lifetime access to resources to late-life cognitive function in older African Americans
    Lisa L Barnes
    Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 13:516-28. 2006
    ..The results suggest that both measures are psychometrically sound in a minority population and that lifetime cognitive activity may contribute to current cognitive function in African Americans...
  4. ncbi request reprint Sex differences in the clinical manifestations of Alzheimer disease pathology
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Arch Gen Psychiatry 62:685-91. 2005
    ....
  5. ncbi request reprint Racial differences in perceived discrimination in a community population of older blacks and whites
    Lisa L Barnes
    Rush Alzheimer s Disease Center and Institute for Healthy Aging
    J Aging Health 16:315-37. 2004
    ..To examine the prevalence of perceived discrimination in an older biracial population and to examine its correlation with depressive symptoms...
  6. ncbi request reprint A longitudinal study of black-white differences in social resources
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois, USA
    J Gerontol B Psychol Sci Soc Sci 59:S146-53. 2004
    ..This study examined the differences in levels of social networks and social engagement between older Blacks and Whites and racial differences in rates of change in social resources over time...
  7. ncbi request reprint Correlates of life space in a volunteer cohort of older adults
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    Exp Aging Res 33:77-93. 2007
    ..The results suggest that the range of environmental movement in older adults is a useful indicator of health in old age and may complement measures of disability...
  8. pmc Hostility and change in cognitive function over time in older blacks and whites
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA
    Psychosom Med 71:652-8. 2009
    ..To test whether the level of hostility predicted the rate of cognitive decline in a community of older blacks and whites and whether the association varied as a function of race...
  9. pmc Effect of a purpose in life on risk of incident Alzheimer disease and mild cognitive impairment in community-dwelling older persons
    Patricia A Boyle
    Rush Alzheimer s Disease Center, 600 S Paulina, Ste 1020B, Chicago, IL 60612, USA
    Arch Gen Psychiatry 67:304-10. 2010
    ..Emerging data suggest that psychological and experiential factors are associated with risk of Alzheimer disease (AD), but the association of purpose in life with incident AD is unknown...
  10. pmc Perceived discrimination and mortality in a population-based study of older adults
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1038, Chicago, IL 60612, USA
    Am J Public Health 98:1241-7. 2008
    ..We examined the relation of individual-level perceived discrimination to mortality in a biracial, population-based sample...
  11. pmc Biracial population study of mortality in mild cognitive impairment and Alzheimer disease
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina Ave, Ste 1038, Chicago, IL 60612, USA
    Arch Neurol 66:767-72. 2009
    ..To assess mortality associated with mild cognitive impairment (MCI) and Alzheimer disease (AD) among older African Americans and whites from an urban community...
  12. ncbi request reprint Racial differences in the progression of cognitive decline in Alzheimer disease
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Depeartment of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Geriatr Psychiatry 13:959-67. 2005
    ..The purpose of the current study was to examine the association of race with rate of cognitive decline in AD...
  13. ncbi request reprint Black-white differences in depressive symptoms among older adults over time
    Kimberly A Skarupski
    Rush Institute for Healthy Aging, 1645 W Jackson, Suite 675, Chicago, IL 60612 3227, USA
    J Gerontol B Psychol Sci Soc Sci 60:P136-42. 2005
    ..225, p < .001) but remained robust. The racial differences increased slightly over time. Our findings support heightened awareness of depression in older Black populations...
  14. pmc Overview and findings from the rush Memory and Aging Project
    David A Bennett
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina, Suite 1028, Chicago, IL 60612, USA
    Curr Alzheimer Res 9:646-63. 2012
    ..The findings are discussed and contextualized...
  15. ncbi request reprint Cognitive decline and survival in Alzheimer's disease
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Int J Geriatr Psychiatry 21:356-62. 2006
    ..To test the association of rate of cognitive decline, an indicator of the severity of the underlying disease process, with risk of death in Alzheimer's disease (AD)...
  16. pmc Neighborhood-level cohesion and disorder: measurement and validation in two older adult urban populations
    Kathleen A Cagney
    Department of Health Studies, The University of Chicago, 5841 South Maryland Avenue, MC 2007, Chicago, IL 60637, USA
    J Gerontol B Psychol Sci Soc Sci 64:415-24. 2009
    ..Drawing from collective efficacy and social disorganization theories, we developed and validated measures of neighborhood-level social processes...
  17. pmc Social engagement and cognitive function in old age
    Kristin R Krueger
    Rush Alzheimer s Disease Center and Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, USA
    Exp Aging Res 35:45-60. 2009
    ..The results confirm that higher level of social engagement in old age is associated with better cognitive function but the association varies across domains of social engagement...
  18. ncbi request reprint Early and late life cognitive activity and cognitive systems in old age
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Center, 600 South Paulina, Suite 1038, Chicago, IL 60612, USA
    J Int Neuropsychol Soc 11:400-7. 2005
    ..The results suggest that past cognitive activity contributes to current cognition principally through its association with cognitive activity in old age...
  19. pmc Association between cognitive activity and cognitive function in older Hispanics
    Maria J Marquine
    Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA
    J Int Neuropsychol Soc 18:1041-51. 2012
    ..Thus, interventions aimed at increasing frequency of participation in cognitively stimulating activity may offer a potential target to reduce cognitive impairment in Hispanics...
  20. ncbi request reprint The apolipoprotein E epsilon 4 allele and decline in different cognitive systems during a 6-year period
    Robert S Wilson
    Rush Alzheimer s Disease Center and Rush Institute for Healthy Aging, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
    Arch Neurol 59:1154-60. 2002
    ..The apolipoprotein E (APOE) epsilon 4 allele is known to influence risk of AD but it has been difficult to establish whether it affects episodic memory differently from other cognitive functions...
  21. ncbi request reprint Change in cognitive function in Alzheimer's disease in African-American and white persons
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Neuroepidemiology 26:16-22. 2006
    ..06), perceptual speed (p = 0.07) and naming (p = 0.08). The results suggest that the rate of cognitive decline in AD is slower in African-Americans compared with whites, particularly for episodic memory...
  22. ncbi request reprint Participation in cognitively stimulating activities and risk of incident Alzheimer disease
    Robert S Wilson
    Rush Alzheimer s Disease Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
    JAMA 287:742-8. 2002
    ..Frequent participation in cognitively stimulating activities has been hypothesized to reduce risk of Alzheimer disease (AD), but prospective data regarding an association are lacking...
  23. ncbi request reprint Loneliness and risk of Alzheimer disease
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
    Arch Gen Psychiatry 64:234-40. 2007
    ..Social isolation in old age has been associated with risk of developing dementia, but the risk associated with perceived isolation, or loneliness, is not well understood...
  24. pmc Cognitive function is associated with the development of mobility impairments in community-dwelling elders
    Aron S Buchman
    Rush Alzheimer s Disease Center, Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Geriatr Psychiatry 19:571-80. 2011
    ..To examine the association of cognitive function with the risk of incident mobility impairments and the rate of declining mobility in older adults...
  25. pmc Racial differences in the association of education with physical and cognitive function in older blacks and whites
    Lisa L Barnes
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 South Paulina, Suite 1038, Chicago, IL 60612, USA
    J Gerontol B Psychol Sci Soc Sci 66:354-63. 2011
    ..We examined racial differences in the cross-sectional association of education with physical and cognitive function performance in older adults...
  26. pmc Life-span cognitive activity, neuropathologic burden, and cognitive aging
    Robert S Wilson
    Rush Alzheimer s Disease Center and Departments of Neurological Sciences, Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA
    Neurology 81:314-21. 2013
    ..To test the hypothesis that cognitive activity across the life span is related to late-life cognitive decline not linked to common neuropathologic disorders...
  27. pmc Late-life social activity and cognitive decline in old age
    Bryan D James
    Rush Alzheimer s Disease Center, Chicago, Illinois 60612, USA
    J Int Neuropsychol Soc 17:998-1005. 2011
    ..These results confirm that more socially active older adults experience less cognitive decline in old age...
  28. pmc Life space and risk of Alzheimer disease, mild cognitive impairment, and cognitive decline in old age
    Bryan D James
    Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Geriatr Psychiatry 19:961-9. 2011
    ....
  29. ncbi request reprint Racial disparities in disability: recent evidence from self-reported and performance-based disability measures in a population-based study of older adults
    Carlos F Mendes de Leon
    Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
    J Gerontol B Psychol Sci Soc Sci 60:S263-71. 2005
    ..Although disability levels have been declining in older adults, there is little current information on racial differences in disability...
  30. pmc Neighborhood social cohesion and disorder in relation to walking in community-dwelling older adults: a multilevel analysis
    Carlos F Mendes de Leon
    Rush Institute for Healthy Aging, Rush University Medical Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
    J Aging Health 21:155-71. 2009
    ..Promotion of walking behavior in older adults may require improvement of the safety and upkeep of the neighborhood environment...
  31. pmc Microinfarct pathology, dementia, and cognitive systems
    Zoe Arvanitakis
    Rush Alzheimer s Disease Center, 600 S Paulina, Suite 1020, Rush University Medical Center, Chicago, IL 60612, USA
    Stroke 42:722-7. 2011
    ..Little is known about the role of microinfarcts in dementia and cognition. We examined microinfarcts and dementia, global cognition, and 5 cognitive systems in community-dwelling older persons...
  32. pmc Recruitment and enrollment of caregivers for a lifestyle physical activity clinical trial
    Caryn D Etkin
    College of Nursing, Rush University Medical Center, 600 S Paulina St, 1080 AAC, Chicago, IL 60612, USA
    Res Nurs Health 35:70-81. 2012
    ..We conclude that social marketing and community-based approaches provide a solid foundation for organizing recruitment activities for clinical trials with older adults...
  33. pmc Purpose in life is associated with mortality among community-dwelling older persons
    Patricia A Boyle
    Rush Alzheimer s Disease Center, Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL 60612, USA
    Psychosom Med 71:574-9. 2009
    ..To assess the association between purpose in life and all-cause mortality in community-dwelling elderly persons...
  34. pmc Childhood adversity and psychosocial adjustment in old age
    Robert S Wilson
    Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
    Am J Geriatr Psychiatry 14:307-15. 2006
    ..The objective of this study was to test the hypothesis that higher level of childhood adversity is associated with lower level of psychosocial adjustment in old age...
  35. pmc Association between life space and risk of mortality in advanced age
    Patricia A Boyle
    Rush Alzheimer s Disease Center, Chicago, Illinois 60612, USA
    J Am Geriatr Soc 58:1925-30. 2010
    ..To examine the association between life space, a measure of functional status that describes the range of movement through the environment covered during daily functioning, and the risk of mortality in older community-based persons...
  36. ncbi request reprint Individual differences in rates of change in cognitive abilities of older persons
    Robert S Wilson
    Department of Neurological Sciences, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
    Psychol Aging 17:179-93. 2002
    ..The results suggest that change in cognitive function in old age primarily reflects person-specific factors rather than an inevitable developmental process...
  37. pmc Relation of driving status to incident life space constriction in community-dwelling older persons: a prospective cohort study
    Raj C Shah
    Rush Alzheimer s Disease Center, Rush University Medical Center, 600 South Paulina, Suite 1022, Chicago, IL 60612, USA
    J Gerontol A Biol Sci Med Sci 67:984-9. 2012
    ..We examined whether being licensed to drive is associated with maintaining spatial movement in older persons initially reporting maximum spatial mobility...
  38. pmc Medicare part D enrollment in a biracial community-based population of older adults
    Kimberly A Skarupski
    Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612 3227, USA
    Gerontologist 49:828-38. 2009
    ..The Medicare Prescription Drug Benefit (Part D) program debuted in January 2006. We ascertained the sociodemographic and health characteristics of Blacks and Whites who enrolled in the early stages of the program...
  39. pmc Diabetes and cognitive systems in older black and white persons
    Zoe Arvanitakis
    Department of Neurological Sciences and Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA
    Alzheimer Dis Assoc Disord 24:37-42. 2010
    ..We found similar effects of diabetes on cognition in both racial groups. Because diabetes is twice as common in blacks, the burden of diabetes on cognition is higher in black than white persons...
  40. pmc Assessing family caregiver skill in managing behavioral symptoms of Alzheimer's disease
    Carol J Farran
    Rush University College of Nursing, Rush University Medical Center, Chicago, IL, USA carol_
    Aging Ment Health 15:510-21. 2011
    ..This measurement study operationalized family caregiver skill in managing behavioral symptoms associated with Alzheimer's disease (AD) by testing a Caregiver Assessment of Behavioral Skill-Self-Report (CAB-SR) measure...
  41. doi request reprint Racial differences on association of depressive symptoms with combined basic and instrumental activities of daily living
    Kumar B Rajan
    1645 West Jackson Boulevard, Suite 675, Chicago, IL 60612
    J Gerontol A Biol Sci Med Sci 69:215-22. 2014
    ..Depressive symptoms are predictive of multiple degenerative diseases in older age adults. However, the association of depressive symptoms with onset and progression of disability have not been studied...
  42. pmc Systemic inflammation in non-demented elderly human subjects: brain microstructure and cognition
    Konstantinos Arfanakis
    Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, USA
    PLoS ONE 8:e73107. 2013
    ....
  43. pmc Faster cognitive decline in the years prior to MR imaging is associated with smaller hippocampal volumes in cognitively healthy older persons
    Debra A Fleischman
    Rush Alzheimer s Disease Center, Rush University Medical Center Chicago, IL, USA Department of Neurological Sciences, Rush University Medical Center Chicago, IL, USA Department of Behavioral Sciences, Rush University Medical Center Chicago, IL, USA
    Front Aging Neurosci 5:21. 2013
    ..The results emphasize the importance of closely examining cognitive change and its association with brain structure during the years in which older persons are considered cognitively healthy...
  44. doi request reprint Age at surgical menopause influences cognitive decline and Alzheimer pathology in older women
    Riley Bove
    From the Program in Translational NeuroPsychiatric Genomics R B, E S, L B C, P L D, Institute for the Neurosciences, Department of Neurology, Brigham and Women s Hospital Harvard Medical School R B, L B C, P L D, Boston, MA and the Departments of Neurological Sciences L L B and Neuropathology J A S, D A B, Rush University Medical Center, Chicago, IL
    Neurology 82:222-9. 2014
    ..To determine the association between age at surgical menopause and both cognitive decline and Alzheimer disease (AD) pathology in 2 longitudinal cohorts...

Research Grants7

  1. Risk Factors for Cognitive Decline in African Americans
    LISA BARNES YOUNG; Fiscal Year: 2007
    ..The faster growth of the aging minority population adds urgency to the need for a better understanding of risk factors related to cognitive decline. ..
  2. Risk Factors for Cognitive Decline in African-Americans
    Lisa L Barnes; Fiscal Year: 2010
    ....