K N Lohr

Summary

Affiliation: RTI International
Country: USA

Publications

  1. ncbi request reprint Assessing "best evidence": issues in grading the quality of studies for systematic reviews
    K N Lohr
    Research Triangle Institute, Research Triangle Park, NC 27709 1294, USA
    Jt Comm J Qual Improv 25:470-9. 1999
  2. ncbi request reprint Health policy issues and applications for evidence-based medicine and clinical practice guidelines
    K N Lohr
    Research Triangle Institute, Research Triangle Park, NC 27709, USA
    Health Policy 46:1-19. 1998
  3. ncbi request reprint Rating the strength of scientific evidence: relevance for quality improvement programs
    Kathleen N Lohr
    RTI International, 3040 Cornwallis Drive, PO Box 12194, Research Triangle Park, NC 27709 2194, USA
    Int J Qual Health Care 16:9-18. 2004
  4. ncbi request reprint Emerging methods in comparative effectiveness and safety: symposium overview and summary
    Kathleen N Lohr
    RTI International, Research Triangle Park, North Carolina, USA
    Med Care 45:S5-8. 2007
  5. doi request reprint Using patient-reported outcomes in clinical practice: challenges and opportunities
    Kathleen N Lohr
    Social and Statistical Sciences, RTI International, 3040 Cornwallis Road, P O Box 12194, Research Triangle Park, NC 27709 2194, USA
    Qual Life Res 18:99-107. 2009
  6. doi request reprint Comparative effectiveness research methods: symposium overview and summary
    Kathleen N Lohr
    RTI International, Research Triangle Park, NC 27709 2194, USA
    Med Care 48:S3-6. 2010
  7. ncbi request reprint Health outcomes methodology symposium: summary and recommendations
    K N Lohr
    Health Services and Policy Research Program, Research Triangle Institute, Research Triangle Park, North Carolina, USA
    Med Care 38:II194-208. 2000
  8. doi request reprint Outcomes and costs of community health worker interventions: a systematic review
    Meera Viswanathan
    RTI International, Research Triangle Park, NC 27709 2194, USA
    Med Care 48:792-808. 2010
  9. ncbi request reprint Perinatal depression: a systematic review of prevalence and incidence
    Norma I Gavin
    RTI International, 3040 Cornwallis Road, PO Box 12194, Research Triangle Park, NC 27709 2194, USA
    Obstet Gynecol 106:1071-83. 2005
  10. ncbi request reprint Impact of local adjuncts to scaling and root planing in periodontal disease therapy: a systematic review
    Arthur J Bonito
    Program on Health Care Organization, Delivery and Access, Health, Social, and Economic Research, Research Triangle Institute International, Research Triangle Park, NC 27709 2194, USA
    J Periodontol 76:1227-36. 2005

Detail Information

Publications43

  1. ncbi request reprint Assessing "best evidence": issues in grading the quality of studies for systematic reviews
    K N Lohr
    Research Triangle Institute, Research Triangle Park, NC 27709 1294, USA
    Jt Comm J Qual Improv 25:470-9. 1999
    ..Clinicians, program administrators, and health policymakers can then be confident in the overall strength of the evidence and study conclusions...
  2. ncbi request reprint Health policy issues and applications for evidence-based medicine and clinical practice guidelines
    K N Lohr
    Research Triangle Institute, Research Triangle Park, NC 27709, USA
    Health Policy 46:1-19. 1998
    ..The methods and information generated from evidence-based guidelines efforts are critical inputs into health policy analysis and decision-making...
  3. ncbi request reprint Rating the strength of scientific evidence: relevance for quality improvement programs
    Kathleen N Lohr
    RTI International, 3040 Cornwallis Drive, PO Box 12194, Research Triangle Park, NC 27709 2194, USA
    Int J Qual Health Care 16:9-18. 2004
    ....
  4. ncbi request reprint Emerging methods in comparative effectiveness and safety: symposium overview and summary
    Kathleen N Lohr
    RTI International, Research Triangle Park, North Carolina, USA
    Med Care 45:S5-8. 2007
    ....
  5. doi request reprint Using patient-reported outcomes in clinical practice: challenges and opportunities
    Kathleen N Lohr
    Social and Statistical Sciences, RTI International, 3040 Cornwallis Road, P O Box 12194, Research Triangle Park, NC 27709 2194, USA
    Qual Life Res 18:99-107. 2009
    ..Introduce and explore issues at an international conference about the use of patient-reported outcomes (PROs) in clinical practice...
  6. doi request reprint Comparative effectiveness research methods: symposium overview and summary
    Kathleen N Lohr
    RTI International, Research Triangle Park, NC 27709 2194, USA
    Med Care 48:S3-6. 2010
    ..A distinguished Planning Committee set the agenda, reviewed more than 70 abstracts, and invited almost 30 speakers; the program emphasized issues of clinical heterogeneity and longitudinal outcomes, including patient-reported measures...
  7. ncbi request reprint Health outcomes methodology symposium: summary and recommendations
    K N Lohr
    Health Services and Policy Research Program, Research Triangle Institute, Research Triangle Park, North Carolina, USA
    Med Care 38:II194-208. 2000
    ..Interest in the philosophy and techniques of the assessment of health outcomes has burgeoned, prompting research funding agencies and others to examine traditional and emerging methods for outcome measurement...
  8. doi request reprint Outcomes and costs of community health worker interventions: a systematic review
    Meera Viswanathan
    RTI International, Research Triangle Park, NC 27709 2194, USA
    Med Care 48:792-808. 2010
    ..We conducted a systematic review on outcomes and costs of community health worker (CHW) interventions. CHWs are increasingly expected to improve health outcomes cost-effectively for the underserved...
  9. ncbi request reprint Perinatal depression: a systematic review of prevalence and incidence
    Norma I Gavin
    RTI International, 3040 Cornwallis Road, PO Box 12194, Research Triangle Park, NC 27709 2194, USA
    Obstet Gynecol 106:1071-83. 2005
    ..We systematically review evidence on the prevalence and incidence of perinatal depression and compare these rates with those of depression in women at non-childbearing times...
  10. ncbi request reprint Impact of local adjuncts to scaling and root planing in periodontal disease therapy: a systematic review
    Arthur J Bonito
    Program on Health Care Organization, Delivery and Access, Health, Social, and Economic Research, Research Triangle Institute International, Research Triangle Park, NC 27709 2194, USA
    J Periodontol 76:1227-36. 2005
    ..Primary outcomes considered are reductions in probing depth (PD) and gains in clinical attachment level (CAL)...
  11. doi request reprint Communication message strategies for increasing knowledge about prostate cancer screening
    Lauren A McCormack
    RTI International, Research Triangle Park, NC 27709, USA
    J Cancer Educ 24:238-43. 2009
    ..This community-based intervention study examined the effects of 2 different message strategies for presenting information about the prostate specific antigen (PSA) test...
  12. ncbi request reprint Screening and treating adults for lipid disorders
    M P Pignone
    Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Am J Prev Med 20:77-89. 2001
    ....
  13. ncbi request reprint Applying cognitive design principles to formatting HRQOL instruments
    P A Mullin
    Research Triangle Institute, Research Triangle Park, NC 27709 2194, USA
    Qual Life Res 9:13-27. 2000
    ....
  14. ncbi request reprint Health services research: an evolving definition of the field
    Kathleen N Lohr
    Research Triangle Institute, Research Triangle Park, NC 27709 2194, USA
    Health Serv Res 37:7-9. 2002
  15. pmc Literacy and health outcomes: a systematic review of the literature
    Darren A DeWalt
    RTI International University of North Carolina Evidence based Practice Center, Research Triangle Park, NC 27599, USA
    J Gen Intern Med 19:1228-39. 2004
    ..To review the relationship between literacy and health outcomes...
  16. ncbi request reprint Tocolytic treatment for the management of preterm labor: a review of the evidence
    Nancy D Berkman
    Research Triangle Institute, Research Triangle Park, NC, USA
    Am J Obstet Gynecol 188:1648-59. 2003
    ....
  17. ncbi request reprint A simple and valid tool distinguished efficacy from effectiveness studies
    Gerald Gartlehner
    University of North Carolina at Chapel Hill, Cecil G Sheps Center for Health Services Research, NC 27599, USA
    J Clin Epidemiol 59:1040-8. 2006
    ..To propose and test a simple instrument based on seven criteria of study design to distinguish effectiveness (pragmatic) from efficacy (explanatory) trials...
  18. ncbi request reprint Assessing the need to update prevention guidelines: a comparison of two methods
    Gerald Gartlehner
    Cecil G Sheps Center for Health Services Research, University of North Carolina, 725 Airport Road, Chapel Hill, NC 27599 7590, USA
    Int J Qual Health Care 16:399-406. 2004
    ..Recently, Shekelle and colleagues proposed a model of limited literature searches with modest expert involvement as a way to reduce the cost and time requirements for assessing whether a guideline needs updating...
  19. ncbi request reprint Screening and interventions for obesity in adults: summary of the evidence for the U.S. Preventive Services Task Force
    Kathleen M McTigue
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Ann Intern Med 139:933-49. 2003
    ..Obesity poses a considerable and growing health burden. This review examines evidence for screening and treating obesity in adults...
  20. ncbi request reprint How to develop a business case for quality
    Kristin L Reiter
    Department of Health Policy and Administration, 1104H McGavran Greenberg Hall, CB 7411, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7411, USA
    Int J Qual Health Care 19:50-5. 2007
    ..To describe the steps in developing a business case for quality-enhancing interventions (QEIs) in health care...
  21. ncbi request reprint Screening for colorectal cancer in adults at average risk: a summary of the evidence for the U.S. Preventive Services Task Force
    Michael Pignone
    University of North Carolina at Chapel Hill, Department of Medicine and Cecil Sheps Center for Health Services Research, 5039 Old Clinic Building, CB 7110, Chapel Hill, NC 27599, USA
    Ann Intern Med 137:132-41. 2002
    ..To assess the effectiveness of different colorectal cancer screening tests for adults at average risk...
  22. ncbi request reprint Bulimia nervosa treatment: a systematic review of randomized controlled trials
    Jennifer R Shapiro
    Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599 7160, USA
    Int J Eat Disord 40:321-36. 2007
    ....
  23. ncbi request reprint Binge eating disorder treatment: a systematic review of randomized controlled trials
    Kimberly A Brownley
    Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina 27599 7160, USA
    Int J Eat Disord 40:337-48. 2007
    ....
  24. ncbi request reprint Anorexia nervosa treatment: a systematic review of randomized controlled trials
    Cynthia M Bulik
    Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7160, USA
    Int J Eat Disord 40:310-20. 2007
    ....
  25. ncbi request reprint Biologics for the treatment of juvenile idiopathic arthritis: a systematic review and critical analysis of the evidence
    Gerald Gartlehner
    Ludwig Boltzmann Institute for Health Technology Assessments, Garnisongasse 7 20, 1090, Vienna, Austria
    Clin Rheumatol 27:67-76. 2008
    ..Clinicians have to be aware of the lack of evidence supporting a long-term net benefit when considering biologics for patients with JIA...
  26. ncbi request reprint Antibiotic therapy for the treatment of preterm labor: a review of the evidence
    John M Thorp
    Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill 27599 7570, USA
    Am J Obstet Gynecol 186:587-92. 2002
    ..The purpose of this study was to evaluate the evidence regarding antibiotics for the treatment of preterm labor...
  27. pmc Efficacy and tolerability of second-generation antidepressants in social anxiety disorder
    Richard A Hansen
    Division of Pharmaceutical Outcomes and Policy, School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA
    Int Clin Psychopharmacol 23:170-9. 2008
    ..Overall, a fair amount of evidence supports the efficacy of escitalopram, fluvoxamine, paroxetine, sertraline, and venlafaxine in social anxiety disorder. The drugs do not differ in efficacy, although their adverse event profiles do...
  28. ncbi request reprint Chemoprevention of breast cancer: a summary of the evidence for the U.S. Preventive Services Task Force
    Linda S Kinsinger
    Cecil G Sheps Center for Health Services Research, Program on Prevention, CB 7508, Wing D, Room 383, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7508, USA
    Ann Intern Med 137:59-69. 2002
    ..Chemoprevention offers promise as a strategy for reducing morbidity and mortality from breast cancer in women. This review examined the evidence for the effectiveness of chemoprevention in women without a history of breast cancer...
  29. ncbi request reprint The efficacy of behavioral interventions to modify dietary fat and fruit and vegetable intake: a review of the evidence
    Alice S Ammerman
    Department of Nutrition, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7400, USA
    Prev Med 35:25-41. 2002
    ..A secondary goal was to explore the relative effectiveness of specific intervention features and among different population subgroups...
  30. ncbi request reprint Screening for depression in adults: a summary of the evidence for the U.S. Preventive Services Task Force
    Michael P Pignone
    University of North Carolina Hospitals, Chapel Hill, USA
    Ann Intern Med 136:765-76. 2002
    ..To clarify whether screening adults for depression in primary care settings improves recognition, treatment, and clinical outcomes...
  31. ncbi request reprint Screening for dementia in primary care: a summary of the evidence for the U.S. Preventive Services Task Force
    Malaz Boustani
    Indiana University School of Medicine, Indianapolis, Indiana, USA
    Ann Intern Med 138:927-37. 2003
    ..Dementia is a large and growing problem but is often not diagnosed in its earlier stages. Screening and earlier treatment could reduce the burden of suffering of this syndrome...
  32. pmc Efficacy and safety of inhaled corticosteroids in patients with COPD: a systematic review and meta-analysis of health outcomes
    Gerald Gartlehner
    Cecil G Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Ann Fam Med 4:253-62. 2006
    ..We wanted to review systematically the efficacy, effectiveness, and safety of inhaled corticosteroids with respect to health outcomes in patients with chronic obstructive pulmonary disease (COPD)...
  33. ncbi request reprint Pharmacologic treatment of bronchiolitis in infants and children: a systematic review
    Valerie J King
    Cecil B Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, 725 Airport Road, Campus Box 7590, Chapel Hill, NC 27599 7595, USA
    Arch Pediatr Adolesc Med 158:127-37. 2004
    ..Up to 3% of all children in their first year of life are hospitalized with bronchiolitis. Bronchodilators and corticosteroids are commonly used treatments, but little consensus exists about optimal management strategies...
  34. ncbi request reprint Screening adults for type 2 diabetes: a review of the evidence for the U.S. Preventive Services Task Force
    Russell Harris
    Sheps Center for Health Services Research, 725 Airport Road, CB 7590, Chapel Hill, NC 27599 2949, USA
    Ann Intern Med 138:215-29. 2003
    ..Type 2 diabetes mellitus is associated with a heavy burden of suffering. Screening for diabetes is controversial...
  35. ncbi request reprint Screening for suicide risk in adults: a summary of the evidence for the U.S. Preventive Services Task Force
    Bradley N Gaynes
    University of North Carolina at Chapel Hill, Chapel Hill 27599, USA
    Ann Intern Med 140:822-35. 2004
    ..Suicide is the 11th leading cause of death and the seventh leading cause of years of potential life lost in the United States. Although suicide is of great public health significance, its clinical management is complicated...
  36. ncbi request reprint Counseling to promote a healthy diet in adults: a summary of the evidence for the U.S. Preventive Services Task Force
    Michael P Pignone
    Division of General Internal Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, USA
    Am J Prev Med 24:75-92. 2003
    ..The purpose of this study was to examine the effectiveness of counseling to promote a healthy diet among patients in primary care settings...
  37. ncbi request reprint Discontinuation rates for selective serotonin reuptake inhibitors and other second-generation antidepressants in outpatients with major depressive disorder: a systematic review and meta-analysis
    Gerald Gartlehner
    Cecil G Sheps Center for Health Services Research, University of North Carolina, Chapel Hill, NC 27599, USA
    Int Clin Psychopharmacol 20:59-69. 2005
    ....
  38. ncbi request reprint The insufficiency of evidence to establish the business case for quality
    Kerry E Kilpatrick
    University of North Carolina at Chapel Hill, Department of Health Policy and Administration, Chapel Hill, NC 27599 7411, USA
    Int J Qual Health Care 17:347-55. 2005
    ..To determine whether a positive financial return on investment for quality-enhancing interventions is more likely for particular health conditions, in specific organizational settings, or with the use of particular interventions...
  39. pmc Interventions to improve health outcomes for patients with low literacy. A systematic review
    Michael Pignone
    Division of General Internal Medicine and Cecil G Sheps Center for Health Services Research, University of North Carolina, Chapel Hill, NC, USA
    J Gen Intern Med 20:185-92. 2005
    ..To perform a systematic review of interventions designed to improve health outcomes for persons with low literacy skills...
  40. ncbi request reprint Challenges in systematic reviews of economic analyses
    Michael Pignone
    University of North Carolina, Chapel Hill, North Carolina 27599 7110, USA
    Ann Intern Med 142:1073-9. 2005
    ..S. Preventive Services T ask Force, particularly our systematic review of the cost-effectiveness of colorectal cancer screening, to illustrate key methodologic challenges and suggest a framework for other researchers in this area...
  41. ncbi request reprint Efficacy and safety of second-generation antidepressants in the treatment of major depressive disorder
    Richard A Hansen
    Division of Pharmaceutical Policy and Evaluative Sciences, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Ann Intern Med 143:415-26. 2005
    ....
  42. ncbi request reprint Screening for prostate cancer: an update of the evidence for the U.S. Preventive Services Task Force
    Russell Harris
    Cecil G Sheps Center for Health Services Research, CB 7590, University of North Carolina School of Medicine, 725 Airport Road, Chapel Hill, NC 27599 7590, USA
    Ann Intern Med 137:917-29. 2002
    ..In U.S. men, prostate cancer is the most common noncutaneous cancer and the second leading cause of cancer death. Screening for prostate cancer is controversial...
  43. ncbi request reprint The comparative efficacy and safety of biologics for the treatment of rheumatoid arthritis: a systematic review and metaanalysis
    Gerald Gartlehner
    Cecil G Sheps Center for Health Services, and School of Public Health, Health Policy and Administration, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    J Rheumatol 33:2398-408. 2006
    ..In addition, dosing regimens and routes of administration differ substantially among biologics. In a systematic review, we assessed the comparative efficacy and safety of biologic agents for RA...