Research Topics
| F DeStefanoSummaryAffiliation: RTI International Country: USA Publications
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Detail Information
Publications
Wheezing lower respiratory disease and vaccination of full-term infantsJohn P Mullooly
Center for Health Research, 3800 N Interstate Ave, Portland, OR 97227, USA
Pharmacoepidemiol Drug Saf 11:21-30. 2002..There have been speculations that increases in vaccinations have caused recent increases in wheezing lower respiratory disease during infancy. We assess possible associations between vaccines and incidence of wheezing in full-term infants...
Safety profile of pneumococcal conjugate vaccines: systematic review of pre- and post-licensure dataFrank Destefano
RTI International, Atlanta, GA 30341, USA
Bull World Health Organ 86:373-80. 2008....- Vaccines and autism: evidence does not support a causal associationF DeStefano
Statistics and Epidemiology Unit, RTI International, Atlanta, Georgia, USA
Clin Pharmacol Ther 82:756-9. 2007.... - Influenza vaccination in children with asthma in health maintenance organizations. Vaccine Safety Datalink TeamP Kramarz
Centers for Disease Control and Prevention, 1600 Clifton Road, MS E61, Atlanta, GA 30333, USA
Vaccine 18:2288-94. 2000..Vaccination coverage could be increased by taking advantage of all opportunities to vaccinate children with asthma whenever they make clinic visits in the fall and early winter... - Does influenza vaccination exacerbate asthma? Analysis of a large cohort of children with asthma. Vaccine Safety Datalink TeamP Kramarz
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Arch Fam Med 9:617-23. 2000..One reason for low influenza vaccine coverage among children with asthma may be concern that influenza vaccination may induce an exacerbation of asthma... - Challenges and controversies in immunization safetyR T Chen
National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Infect Dis Clin North Am 15:21-39, viii. 2001..It also provides information on how various safety research is conducted, some of the concurrent challenges, and finally, some guidance on communicating with patients on vaccine risks... - Childhood vaccinations, vaccination timing, and risk of type 1 diabetes mellitusF DeStefano
National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
Pediatrics 108:E112. 2001..To evaluate suggested associations between childhood vaccinations, particularly against hepatitis B and Haemophilus influenzae type b, and risk of developing type 1 diabetes; and to determine whether timing of vaccination influences risk... - The incidence of Kawasaki syndrome in West Coast health maintenance organizationsE D Belay
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Pediatr Infect Dis J 19:828-32. 2000..Kawasaki syndrome (KS) causes an acute vasculitis of unknown etiology. It is a leading cause of acquired heart disease of children in Japan and the United States... - The Vaccine Safety Datalink projectF DeStefano
National Immunization Program MS F34, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Pharmacoepidemiol Drug Saf 10:403-6. 2001..A cohort study was conducted that allowed estimation of incidence rates of intussusception and attributable risks associated with rotavirus vaccine... - The Vaccine Safety Datalink: immunization research in health maintenance organizations in the USAR T Chen
National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Bull World Health Organ 78:186-94. 2000.... - Does influenza vaccination prevent asthma exacerbations in children?P Kramarz
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Pediatr 138:306-10. 2001..The effectiveness of influenza vaccine in preventing influenza-related asthma exacerbations, however, is not known. We evaluated influenza vaccine effectiveness in protecting children against influenza-related asthma exacerbations... - Autism and measles-mumps-rubella vaccination: controversy laid to rest?F DeStefano
National Center on Birth Defects and Developmental Disabilities, Atlanta, Georgia 30341 3724, USA
CNS Drugs 15:831-7. 2001..Currently, the weight of the available epidemiological and related evidence does not support a causal association between MMR vaccine, or any other vaccine or vaccine constituent, and autism... - Epidemiology of autoimmune reactions induced by vaccinationR T Chen
Vaccine Safety and Development Activity, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Autoimmun 16:309-18. 2001..Examples include the possible association of immunization and multiple sclerosis (and other demyelinating diseases), type 1 diabetes mellitus, Guillain-Barre Syndrome, idiopathic thrombocytopenic purpura, and rheumatoid arthritis... - Population-based study of rotavirus vaccination and intussusceptionP Kramarz
National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA, USA
Pediatr Infect Dis J 20:410-6. 2001..0. The attributable risk was one case of intussusception per 11 073 children vaccinated. CONCLUSIONS: RRV-TV is associated with an increased risk of intussusception. The risk is greatest 3 to 7 days after the first vaccination dose... - MMR vaccine and autism: a review of the evidence for a causal associationF DeStefano
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mailstop F34, Atlanta, GA 30341-3724, USA
Mol Psychiatry 7:S51-2. 2002 - A retrospective cohort study of the association of varicella vaccine failure with asthma, steroid use, age at vaccination, and measles-mumps-rubella vaccinationThomas Verstraeten
Epidemic Intelligence Service Program, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Pediatrics 112:e98-103. 2003..We assessed the association of varicella breakthrough with asthma, steroids, age at varicella vaccination, and timing of measles-mumps-rubella (MMR) vaccination... - Hepatitis B vaccination among adolescents in 3 large health maintenance organizationsIdalia M Gonzalez
Epidemiology Program Office, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Pediatrics 110:929-34. 2002..Little is known about the implementation of these recommendations in a managed care setting. The objective of this study was to determine the impact of ACIP recommendations on HB vaccination among adolescents in 3 managed care settings... - Letter to the editor. The safety of thimerosal in newborn and infant vaccinesWilliam W Thompson
Vaccine 23:281-2. 2004 - Early thimerosal exposure and neuropsychological outcomes at 7 to 10 yearsWilliam W Thompson
National Center for Immunizations and Respiratory Diseases, Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
N Engl J Med 357:1281-92. 2007..It has been hypothesized that early exposure to thimerosal, a mercury-containing preservative used in vaccines and immune globulin preparations, is associated with neuropsychological deficits in children... - Immunogenicity and reactogenicity of 1 versus 2 doses of trivalent inactivated influenza vaccine in vaccine-naive 5-8-year-old childrenKathleen M Neuzil
Program for Appropriate Technology in Health, School of Medicine, University of Washington, Seattle, Seattle, WA 98107, USA
J Infect Dis 194:1032-9. 2006..This study assessed the need for a second dose of TIV in this age group... - Trends in diagnosis rates for autism and ADHD at hospital discharge in the context of other psychiatric diagnosesDavid S Mandell
Center for Mental Health Policy and Services Research, University of Pennsylvania, 3535 Market Street, Philadelphia, PA 19104, USA
Psychiatr Serv 56:56-62. 2005.... - MMR vaccine and autism: an update of the scientific evidenceFrank Destefano
National Immunization Program, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop E61, Atlanta, Georgia 30333, USA
Expert Rev Vaccines 3:19-22. 2004..The evidence now is convincing that the measles-mumps-rubella vaccine does not cause autism or any particular subtypes of autistic spectrum disorder... - Age at first measles-mumps-rubella vaccination in children with autism and school-matched control subjects: a population-based study in metropolitan atlantaFrank Destefano
National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Pediatrics 113:259-66. 2004..To compare ages at first measles-mumps-rubella (MMR) vaccination between children with autism and children who did not have autism in the total population and in selected subgroups, including children with regression in development... - Safety of thimerosal-containing vaccines: a two-phased study of computerized health maintenance organization databasesThomas Verstraeten
Epidemic Intelligence Service Program, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Pediatrics 112:1039-48. 2003..Conflicting results were found at different HMOs for certain outcomes. For resolving the conflicting findings, studies with uniform neurodevelopmental assessments of children with a range of cumulative thimerosal exposures are needed... - MMR vaccination and autism: is there a link?Frank Destefano
Expert Opin Drug Saf 1:115-20. 2002..Currently, the weight of the available epidemiological and related evidence does not support a causal link between MMR vaccine and autism... - Vaccinations and risk of central nervous system demyelinating diseases in adultsFrank Destefano
National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Arch Neurol 60:504-9. 2003..Several case reports of the onset or exacerbation of multiple sclerosis or other demyelinating conditions shortly after vaccination have suggested that vaccines may increase the risk of demyelinating diseases... - Childhood vaccinations and risk of asthmaFrank Destefano
Centers for Disease Control and Prevention, Atlanta, GA, USA
Pediatr Infect Dis J 21:498-504. 2002..The weak associations for Hib and hepatitis B vaccines seem to be at least partially accounted for by health care utilization or information bias...