Alec Roy

..This study was an examination of whether a family history of suicide is associated with attempts at suicide among alcoholics...

..To examine the risk factors for suicidal behaviour in human immunodeficiency virus (HIV) positive patients...

..These results suggest the possibility that ERG blue cone amplitudes may be a neurobiologic marker related to central dopamine function in cocaine-dependent patients...

..Thus, these data suggest that after protracted abstinence from cocaine there is no marked dysregulation of CRH systems as measured by CSF CRH concentrations...

..These results suggest that social, personality, family, developmental and psychiatric risk factors may predispose to suicidal behavior in drug-dependent individuals...

..To examine distal risk factors for suicidal behavior in alcoholics...

..Further studies seem warranted examining for differences between African Americans and Caucasians for risk factors for suicidal behavior...

..To examine whether childhood trauma effect the age of first attempting suicide and the number of attempts...

..These results suggest that a family history of suicide, which is known to increase the risk of suicidal behavior, may also be associated with an earlier age of first attempting suicide...

..The results showed that there were significant relationships, albeit small, between CTQ scores and BIS impulsivity scores. These results suggest that childhood trauma may be one determinant of impulsivity as an adult...

..The generalizability of these results to the general population and to other diagnostic groups requires further study...

..Female sex, childhood trauma, and a family history of suicidal behavior are three well established risk factors for attempting suicide. However, interactions between these three factors in attempting suicide have been little studied...

..The limitations of the study are discussed...

..Childhood trauma interacts with low expressing 5-HTTLPR genotypes to increase the risk of suicidal behavior among patients with substance dependence...

..These findings suggest the possibility that childhood trauma may have an effect on central monoamine function as an adult...

..These data suggest that childhood trauma and variants of the FKBP5 gene may interact to increase the risk for attempting suicide...

..Therefore, childhood trauma may be a risk factor predisposing schizophrenic patients to attempt suicide...

....

..To examine whether childhood trauma may have a relationship to hypothalamic-pituitary-adrenal (HPA) axis function as an adult...

..Longitudinal studies among suicide attempters, including measures of depression, may further evaluate the possible relevance of resilience to suicidal behavior...

..Thus, developmental, personality, family history, social, and comorbidity risk factors may differentiate alcohol dependent patients who have attempted suicide from those who have not...

..CSF monoamine metabolite concentrations were not related to cocaine craving in withdrawn cocaine-dependent patients...

..The relationship between CTQ and BGHA scores suggests the possibility that childhood trauma may be one determinant of aggression in prisoners...

..Suicide risk in diabetics appears to be multifactorial and includes gender, developmental, personality, psychiatric, and substance abuse determinants...

..Main effects of CRHBP rs6453267 and CRHR1 rs9900679, both unique to African ancestry, were detected. CRHBP variation may predispose, independently and additively, to suicidal behavior in individuals who have experienced childhood trauma...

..We explored differences between high and low-impulsive incarcerated individuals in the context of lifetime self-mutilation, suicide ideation and suicide attempt...

..Future studies of suicidal behavior should examine both genetic and environmental variables and examine for gene-environment interactions...

..A lifetime history of attempting suicide, or of having suicidal ideation, is frequent in prisoners. Risk factors include family, developmental, aggression, personality, psychiatric, and substance abuse factors...

..The aim of our study is then to analyze psychological and judicial features of a subgroup of inmates with substance abuse...

..05 for all). CONCLUSION: Suicidal behavior in opiate dependent patients may involve risk factors from the family, childhood, personality, psychiatric, and physical domains...

..Therefore, it was decided to examine the possible role of a gene in the regulation of BDNF activity in relation to suicidal behaviour among depressed patients...

..To examine the relationship of childhood trauma to depressive symptoms in type 1 diabetes, a chronic disease in which the frequency of depression is increased...

..Suicidal behavior in unipolar depression appears to be a multidetermined act, with sociodemographic, developmental, and personality determinants...

..These data suggest the possibility of a relationship between insomnia and suicidality in prisoners. Assessing insomnia may be helpful when evaluating the risk of suicidality in prisoners...

..A family history of suicide may be a useful clinical indicator that a prisoner is at increased risk for suicidal behaviour and may have problems with impulsive-aggression...

..To examine the relationship between childhood trauma and prevalence of cardiovascular disease (CVD) (either coronary disease or stroke) in Type 1 diabetes (DM)...

..Thus these results suggest that attempting suicide is common among cocaine dependent patients and that both distal and proximal risk factors may play a role...

..We wished to examine whether resilience might be a protective factor in relation to suicidal behavior...

..CONCLUSIONS: Recently abstinent cocaine-dependent patients may show dysregulation of the central dopaminergic system...

..This article discusses the frequency of suicidal behavior in schizophrenia, offers a model for understanding it, and discusses various aspects of the management of the at-risk schizophrenic patient...

..Further studies of the relationship of a family history of suicide to personality are needed in other populations and incorporating biologic measures...

..Comorbidity appears to be an important determinant of suicidal behavior...

..It was therefore decided to combine them and examine if the combination would identify patients at even increased risk for suicidal behavior...

..Thus, admission total serum cholesterol does not appear to be clinically useful in the assessment of suicidal behavior in cocaine-dependent patients...

..Dal-OUTCOMES is a multicenter, randomized, double-blind, placebo-controlled trial designed to test the hypothesis that CETP inhibition with dalcetrapib reduces cardiovascular morbidity and mortality in patients with recent ACS...

..Thus, these results suggest the possibility that childhood trauma may be a determinant of the personality dimension of hostility as an adult...

..CONCLUSIONS: Childhood trauma may be a determinant of neuroticism. This may be one way in which childhood trauma plays a role in the development of psychiatric disorders. General population studies are needed...

..In this study, various childhood traumas were found to be significantly associated withsuicidal behavior among adult male cocaine dependent patients...

..In the present review we aimed to summarize the empirical and clinical literature on controlling the access to means of suicide...

..These results suggest that attempting suicide is common among opiate dependent patients and that both distal and proximal risk factors may play a role...

..035). CONCLUSIONS: These data confirm our previous reports that MZ co-twins show greater concordance for suicidal behavior than DZ co-twins, consistent with genetic influence...

..CONCLUSION: These results, in a small sample, suggest the possibility that the 17 779C allele of the TPH gene may be associated with an increased risk of suicide. Further studies in larger samples are needed...

..The hypothesis we aimed to test in this study was the existence of an association between childhood trauma and aggression in two distinct samples of Italian and French suicide attempters...

..CONCLUSIONS: Patients with a reduced ERG response may represent a subgroup more vulnerable to cocaine craving and future relapse...

....

..Depression is a common psychiatric disorder among diabetic persons and has been shown in cross-sectional studies to be associated with the vascular complications of diabetes...

..Neuropsychopharmacology (2007) 32, 190-196. doi:10.1038/sj.npp.1301177; published online 16 August 2006...

..We sought to report the 6-year incidence of proteinuria and associated risk factors in African Americans with type 1 diabetes...

..A high percentage of suicide victims have seen a primary care physician in the months before committing suicide. Thus, primary care physicians may play an important role in suicide prevention...

..To develop a panel of markers able to extract full haplotype information for candidate genes in alcoholism, other addictions and disorders of mood and anxiety...