Katrina F Cooper
Affiliation: Rowan University
Jezek J, Smethurst D, Stieg D, Kiss Z, Hanley S, Ganesan V, et al
. Cyclin C: The Story of a Non-Cycling Cyclin. Biology (Basel). 2019;8: pubmed publisher
..Here, we review and discuss the biology of cyclin C, focusing mainly on its transcriptional and non-transcriptional roles in tumor promotion or suppression. ..
Smethurst D, Cooper K. ER fatalities-The role of ER-mitochondrial contact sites in yeast life and death decisions. Mech Ageing Dev. 2017;161:225-233 pubmed publisher
..This review focuses on recent findings in yeast that shed light on how ER-mitochondrial communication mediates critical cell fate decisions. ..
Stieg D, Willis S, Ganesan V, Ong K, Scuorzo J, Song M, et al
. A complex molecular switch directs stress-induced cyclin C nuclear release through SCFGrr1-mediated degradation of Med13. Mol Biol Cell. 2018;29:363-375 pubmed publisher
..Taken together, these results support a model in which this IDR of Med13 plays a key role in controlling a molecular switch that dictates cell fate following exposure to adverse environments. ..
Jezek J, Cooper K, Strich R. Reactive Oxygen Species and Mitochondrial Dynamics: The Yin and Yang of Mitochondrial Dysfunction and Cancer Progression. Antioxidants (Basel). 2018;7: pubmed publisher
..Here, we review the latest findings on the intricate relationship between mitochondrial dynamics and ROS production, focusing mainly on its role in malignant disease. ..