Anurag K Singh

Summary

Affiliation: Roswell Park Cancer Institute
Country: USA

Publications

  1. ncbi request reprint Magnetic resonance imaging-directed transrectal ultrasonography-guided biopsies in patients at risk of prostate cancer
    Jean Baptiste Lattouf
    Urologic Oncology Branch, DCDT, Molecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    BJU Int 99:1041-6. 2007
  2. pmc Hope for progress after 40 years of futility? Novel approaches in the treatment of advanced stage III and IV non-small-cell-lung cancer: Stereotactic body radiation therapy, mediastinal lymphadenectomy, and novel systemic therapy
    Simon Fung Fee Fung
    Department of Radiation Medicine, Roswell Park Cancer Institute, University at Buffalo School of Medicine, Elm and Carlton Streets, Buffalo, New York, 14263, USA
    J Carcinog 11:20. 2012
  3. doi request reprint Increasing age and treatment modality are predictors for subsequent diagnosis of bladder cancer following prostate cancer diagnosis
    Anurag K Singh
    Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Int J Radiat Oncol Biol Phys 78:1086-94. 2010
  4. pmc Initial clinical experience with real-time transrectal ultrasonography-magnetic resonance imaging fusion-guided prostate biopsy
    Anurag K Singh
    Radiation Medicine Department, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    BJU Int 101:841-5. 2008
  5. pmc TBI with lung dose reduction does not improve hematopoietic cell homing to BM during allogeneic transplantation
    A K Singh
    Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Bone Marrow Transplant 45:25-30. 2010
  6. ncbi request reprint Patient selection determines the prostate cancer yield of dynamic contrast-enhanced magnetic resonance imaging-guided transrectal biopsies in a closed 3-Tesla scanner
    Anurag K Singh
    Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 1642, USA
    BJU Int 101:181-5. 2008
  7. pmc Intrarectal amifostine during external beam radiation therapy for prostate cancer produces significant improvements in Quality of Life measured by EPIC score
    Nicole L Simone
    Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Int J Radiat Oncol Biol Phys 70:90-5. 2008
  8. doi request reprint Pretreatment nutritional status and locoregional failure of patients with head and neck cancer undergoing definitive concurrent chemoradiation therapy
    Mary E Platek
    Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA
    Head Neck 33:1561-8. 2011
  9. pmc Early observed transient prostate-specific antigen elevations on a pilot study of external beam radiation therapy and fractionated MRI guided high dose rate brachytherapy boost
    Anurag K Singh
    Radiation Oncology Branch, National Cancer Institute, NIH DHHS, Bldg 10, CRC Rm B2 3561, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Radiat Oncol 1:28. 2006
  10. pmc Simultaneous integrated boost of biopsy proven, MRI defined dominant intra-prostatic lesions to 95 Gray with IMRT: early results of a phase I NCI study
    Anurag K Singh
    Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, USA
    Radiat Oncol 2:36. 2007

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Magnetic resonance imaging-directed transrectal ultrasonography-guided biopsies in patients at risk of prostate cancer
    Jean Baptiste Lattouf
    Urologic Oncology Branch, DCDT, Molecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    BJU Int 99:1041-6. 2007
    ..5 t) mri...
  2. pmc Hope for progress after 40 years of futility? Novel approaches in the treatment of advanced stage III and IV non-small-cell-lung cancer: Stereotactic body radiation therapy, mediastinal lymphadenectomy, and novel systemic therapy
    Simon Fung Fee Fung
    Department of Radiation Medicine, Roswell Park Cancer Institute, University at Buffalo School of Medicine, Elm and Carlton Streets, Buffalo, New York, 14263, USA
    J Carcinog 11:20. 2012
    ..The utility of these techniques in advanced stage therapy and potential methods of combining these novel techniques with systemic therapy to improve survival are discussed...
  3. doi request reprint Increasing age and treatment modality are predictors for subsequent diagnosis of bladder cancer following prostate cancer diagnosis
    Anurag K Singh
    Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Int J Radiat Oncol Biol Phys 78:1086-94. 2010
    ..To determine the effect of prostate cancer therapy (surgery or external beam irradiation, or both or none) on the actuarial incidence of subsequent bladder cancer...
  4. pmc Initial clinical experience with real-time transrectal ultrasonography-magnetic resonance imaging fusion-guided prostate biopsy
    Anurag K Singh
    Radiation Medicine Department, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    BJU Int 101:841-5. 2008
    ..To evaluate the feasibility and utility of registration and fusion of real-time transrectal ultrasonography (TRUS) and previously acquired magnetic resonance imaging (MRI) to guide prostate biopsies...
  5. pmc TBI with lung dose reduction does not improve hematopoietic cell homing to BM during allogeneic transplantation
    A K Singh
    Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Bone Marrow Transplant 45:25-30. 2010
    ..TBI does not improve the homing of lineage-negative donor BM cells to the recipient marrow. The homing of lineage-negative, Kit-positive donor BM cells was significantly worse following TBI, with or without lung dose reduction...
  6. ncbi request reprint Patient selection determines the prostate cancer yield of dynamic contrast-enhanced magnetic resonance imaging-guided transrectal biopsies in a closed 3-Tesla scanner
    Anurag K Singh
    Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 1642, USA
    BJU Int 101:181-5. 2008
    ....
  7. pmc Intrarectal amifostine during external beam radiation therapy for prostate cancer produces significant improvements in Quality of Life measured by EPIC score
    Nicole L Simone
    Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Int J Radiat Oncol Biol Phys 70:90-5. 2008
    ..To test whether intrarectal amifostine limits symptoms of radiation proctitis, measured by using the Radiation Therapy Oncology Group (RTOG) gastrointestinal (GI) toxicity score and the Expanded Prostate Cancer Index Composite (EPIC) score...
  8. doi request reprint Pretreatment nutritional status and locoregional failure of patients with head and neck cancer undergoing definitive concurrent chemoradiation therapy
    Mary E Platek
    Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA
    Head Neck 33:1561-8. 2011
    ....
  9. pmc Early observed transient prostate-specific antigen elevations on a pilot study of external beam radiation therapy and fractionated MRI guided high dose rate brachytherapy boost
    Anurag K Singh
    Radiation Oncology Branch, National Cancer Institute, NIH DHHS, Bldg 10, CRC Rm B2 3561, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Radiat Oncol 1:28. 2006
    ..To report early observation of transient PSA elevations on this pilot study of external beam radiation therapy and magnetic resonance imaging (MRI) guided high dose rate (HDR) brachytherapy boost...
  10. pmc Simultaneous integrated boost of biopsy proven, MRI defined dominant intra-prostatic lesions to 95 Gray with IMRT: early results of a phase I NCI study
    Anurag K Singh
    Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, USA
    Radiat Oncol 2:36. 2007
    ..To assess the feasibility and early toxicity of selective, IMRT-based dose escalation (simultaneous integrated boost) to biopsy proven dominant intra-prostatic lesions visible on MRI...
  11. doi request reprint Radiation treatment interruptions greater than one week and low hemoglobin levels (12 g/dL) are predictors of local regional failure after definitive concurrent chemotherapy and intensity-modulated radiation therapy for squamous cell carcinoma of the head
    Susan A McCloskey
    Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA
    Am J Clin Oncol 32:587-91. 2009
    ....
  12. pmc Molecular and clinical responses in a pilot study of gefitinib with paclitaxel and radiation in locally advanced head-and-neck cancer
    Carter Van Waes
    Head and Neck Surgery Branch, National Institute of Deafness and Communication Disorders, National Institutes of Health, Bethesda, MD, USA
    Int J Radiat Oncol Biol Phys 77:447-54. 2010
    ....
  13. doi request reprint Pretreatment weight status and weight loss among head and neck cancer patients receiving definitive concurrent chemoradiation therapy: implications for nutrition integrated treatment pathways
    Mary E Platek
    Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, NY, USA
    Support Care Cancer 21:2825-33. 2013
    ..The purpose was to examine the effect of pretreatment weight status on loco-regional progression for patients with squamous cell carcinoma of the head and neck (SCCHN) after receiving definitive concurrent chemoradiation therapy (CCRT)...
  14. doi request reprint Quantification of the effect of treatment duration on local-regional failure after definitive concurrent chemotherapy and intensity-modulated radiation therapy for squamous cell carcinoma of the head and neck
    Mary E Platek
    Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Head Neck 35:684-8. 2013
    ..The purpose of this study was to quantify the effect of treatment duration on locoregional progression after definitive concurrent chemoradiation (CCRT) for squamous cell carcinoma of the head and neck (SCCHN)...
  15. pmc Real-time MRI-TRUS fusion for guidance of targeted prostate biopsies
    Sheng Xu
    Philips Research North America, Briarcliff, New York, USA
    Comput Aided Surg 13:255-64. 2008
    ..The fusion system has been used in more than 20 patients to guide biopsies with almost no modification of the conventional protocol. Retrospective clinical evaluation suggests that clinically acceptable spatial accuracy can be achieved...
  16. doi request reprint Survival rates and prognostic factors for infiltrating salivary duct carcinoma: Analysis of 228 cases from the Surveillance, Epidemiology, and End Results database
    Vijayvel Jayaprakash
    Department of Head and Neck Plastic and Reconstructive Surgery, Roswell Park Cancer Institute, Buffalo, New York Department of Dentistry and Maxillofacial Prosthetics, Roswell Park Cancer Institute, Buffalo, New York
    Head Neck 36:694-701. 2014
    ..The survival rates and prognostic factors for salivary duct carcinoma (SDC) are not clear...
  17. ncbi request reprint Efficacy of CD34+ stem cell dose in patients undergoing allogeneic peripheral blood stem cell transplantation after total body irradiation
    Anurag K Singh
    Radiation Oncology Branch, National Cancer Institute, Bethesda, Maryland 20892, USA
    Biol Blood Marrow Transplant 13:339-44. 2007
    ..A method for assessing risk of mortality by CD34(+) dose as a continuous variable is presented. Risk of mortality decreased with CD34(+) doses between 4-8 x 10(6) cells/kg and then began to increase...
  18. pmc Improved survival following surgery and radiation therapy for olfactory neuroblastoma: analysis of the SEER database
    Mary E Platek
    Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA
    Radiat Oncol 6:41. 2011
    ..Olfactory Neuroblastoma is a rare malignant tumor of the olfactory tract. Reports in the literature comparing treatment modalities for this tumor are limited...
  19. doi request reprint Survival differences between organ preservation surgery and definitive radiotherapy in early supraglottic squamous cell carcinoma
    Hassan Arshad
    Department of Head and Neck Plastic and Reconstructive Surgery, Roswell Park Cancer Institute, Buffalo, New York, USA
    Otolaryngol Head Neck Surg 150:237-44. 2014
    ..However, studies comparing the effectiveness of these 2 techniques are lacking. This study compares the survival outcomes in early SGC patients treated with OPS versus RT...
  20. doi request reprint High incidence of oral dysesthesias on a trial of gefitinib, Paclitaxel, and concurrent external beam radiation for locally advanced head and neck cancers
    Hadley Sharp
    Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA
    Am J Clin Oncol 31:557-60. 2008
    ....
  21. ncbi request reprint A second transient prostate-specific antigen elevation after external-beam radiation therapy and fractionated magnetic resonance imaging-guided high-dose rate brachytherapy boost
    Mark V Mishra
    Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Clin Genitourin Cancer 5:406-8. 2007
    ....
  22. doi request reprint Nicotinic modulation of therapeutic response in vitro and in vivo
    Graham W Warren
    Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Int J Cancer 131:2519-27. 2012
    ..These findings imply that during tobacco use, nicotine may function as a systemic agent through acute and reversible regulation of HIF-1α expression and a decreased therapeutic response...
  23. pmc Pretreatment predictors of death from other causes in men with prostate cancer
    Nicole L Simone
    Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Urol 180:2447-51; discussion 2451-2. 2008
    ..Accurate stratification of patients by risk of other cause mortality may reduce needless treatment preventing morbidity and expense...
  24. ncbi request reprint Pretransplant pulmonary function tests predict risk of mortality following fractionated total body irradiation and allogeneic peripheral blood stem cell transplant
    Anurag K Singh
    Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Radiat Oncol Biol Phys 66:520-7. 2006
    ..To determine the value of pulmonary function tests (PFTs) done before peripheral blood stem cell transplant (PBSCT) in predicting mortality after total body irradiation (TBI) performed with or without dose reduction to the lung...
  25. doi request reprint Automated tobacco assessment and cessation support for cancer patients
    Graham W Warren
    Department of Radiation Oncology, Medical University of South Carolina, Charleston, South Carolina Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, South Carolina Department of Health Behavior, Roswell Park Cancer Institute, Buffalo, New York
    Cancer 120:562-9. 2014
    ..Tobacco assessment and cessation support are not routinely included in cancer care. An automated tobacco assessment and cessation program was developed to increase the delivery of tobacco cessation support for cancer patients...
  26. pmc Vascular priming enhances chemotherapeutic efficacy against head and neck cancer
    Margaret Folaron
    Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Oral Oncol 49:893-902. 2013
    ..In this study, we investigated the potential of targeting the established tumor vasculature in combination with chemotherapy in head and neck cancer...
  27. pmc A prospective study of differences in duodenum compared to remaining small bowel motion between radiation treatments: implications for radiation dose escalation in carcinoma of the pancreas
    Anurag K Singh
    Radiation Oncology Branch, National Cancer Institute, Bethesda, MD 20892, USA
    Radiat Oncol 1:33. 2006
    ..As a foundation for a dose escalation trial, we sought to characterize duodenal and non-duodenal small bowel organ motion between fractions of pancreatic radiation therapy...
  28. ncbi request reprint Increased risk of bone loss without fracture risk in long-term survivors after allogeneic stem cell transplantation
    Bipin N Savani
    Stem Cell Allogeneic Transplantation Section, Hematology Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1202, USA
    Biol Blood Marrow Transplant 13:517-20. 2007
    ..Our data shows that BL is a long-term posttransplant complication, and emphasize the importance of serial BMD scans, and the treatment of BL with biphosphonates reserved for worsening BL or additional risk factors...
  29. ncbi request reprint Intrarectal amifostine suspension may protect against acute proctitis during radiation therapy for prostate cancer: a pilot study
    Anurag K Singh
    Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Int J Radiat Oncol Biol Phys 65:1008-13. 2006
    ..Our goal was to test the ability of intrarectal amifostine to limit symptoms of radiation proctitis...
  30. doi request reprint Quantification of incidental mediastinal and hilar irradiation delivered during definitive stereotactic body radiation therapy for peripheral non-small cell lung cancer
    Kate L Martin
    Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Med Dosim 37:182-5. 2012
    ..Treatment of peripheral upper lobe lung tumors delivers less incidental irradiation to the paratracheal lymph nodes with lower likelihood of therapeutic benefit...
  31. pmc Accuracy of self-reported tobacco assessments in a head and neck cancer treatment population
    Graham W Warren
    Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Radiother Oncol 103:45-8. 2012
    ..Accuracy increased by 14.9% with weekly vs. baseline self-reported assessments. Data confirm that head and neck cancer patients misrepresent true tobacco use during treatment...
  32. pmc Nicotine and lung cancer
    Graham W Warren
    Department of Radiation Oncology, Medical University of South Carolina, Charleston, SC, USA and Roswell Park Cancer Institute, Buffalo, NY, USA Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, USA and Roswell Park Cancer Institute, Buffalo, NY, USA
    J Carcinog 12:1. 2013
    ..Data suggest that nicotine may be an important mechanism by which tobacco promotes tumor development, progression, and resistance to cancer treatment...
  33. doi request reprint Treatment of early-stage uterine papillary serous carcinoma at Roswell Park Cancer Institute, 1992-2006
    Nana E Tchabo
    Division of Gynecologic Oncology, Department of Surgery, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Gynecol Oncol 115:249-56. 2009
    ..Optimal management of early-stage uterine papillary serous carcinoma (UPSC) remains controversial. We reviewed our outcomes in this patient population...
  34. pmc Mild elevation of body temperature reduces tumor interstitial fluid pressure and hypoxia and enhances efficacy of radiotherapy in murine tumor models
    Arindam Sen
    Department of Immunology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Cancer Res 71:3872-80. 2011
    ..These data suggest, for the first time, that environmental manipulation of normal vasomotor function is capable of achieving therapeutically beneficial changes in IFP and microvascular function in the tumor microenvironment...
  35. ncbi request reprint Alkaline phosphatase level increase with initiation of hormone therapy for prostate cancer portends poor prognosis with rapid progression to bone metastases: a case report and review of the literature
    Michael W Brown
    National Institutes of Health National Cancer Institute, Bethesda, MD 20892, USA
    Clin Genitourin Cancer 4:293-5. 2006
    ..In this report, we explore the role of serum ALP as an indicator for patients who develop early metastases and thus might benefit from early initiation of aggressive secondary treatments such as chemotherapy...
  36. pmc Closed-loop control in fused MR-TRUS image-guided prostate biopsy
    Sheng Xu
    Philips Research North America, Briarcliff, NY 10510, USA
    Med Image Comput Comput Assist Interv 10:128-35. 2007
    ..The accuracy of the system is 2.3 +/- 0.9 mm in phantom studies. The results of twelve patient studies show that prostate motion can be effectively compensated using closed-loop control...
  37. pmc Design and preliminary accuracy studies of an MRI-guided transrectal prostate intervention system
    Axel Krieger
    Department of Mechanical Engineering, Johns Hopkins University, Baltimore, USA
    Med Image Comput Comput Assist Interv 10:59-67. 2007
    ..Moreover, the portable design of the system using only standard MRI image sequences and minimal custom scanner interfacing allows the system to be easily used on different MRI scanners...