Research Topics
| Anurag K SinghSummaryAffiliation: Roswell Park Cancer Institute Country: USA Publications
| Collaborators
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Detail Information
Publications
Magnetic resonance imaging-directed transrectal ultrasonography-guided biopsies in patients at risk of prostate cancerJean Baptiste Lattouf
Urologic Oncology Branch, DCDT, Molecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
BJU Int 99:1041-6. 2007..5 t) mri...
Initial clinical experience with real-time transrectal ultrasonography-magnetic resonance imaging fusion-guided prostate biopsyAnurag K Singh
Radiation Medicine Department, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
BJU Int 101:841-5. 2008..To evaluate the feasibility and utility of registration and fusion of real-time transrectal ultrasonography (TRUS) and previously acquired magnetic resonance imaging (MRI) to guide prostate biopsies...
Increasing age and treatment modality are predictors for subsequent diagnosis of bladder cancer following prostate cancer diagnosisAnurag K Singh
Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Int J Radiat Oncol Biol Phys 78:1086-94. 2010..To determine the effect of prostate cancer therapy (surgery or external beam irradiation, or both or none) on the actuarial incidence of subsequent bladder cancer...- Patient selection determines the prostate cancer yield of dynamic contrast-enhanced magnetic resonance imaging-guided transrectal biopsies in a closed 3-Tesla scannerAnurag K Singh
Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 1642, USA
BJU Int 101:181-5. 2008.... - TBI with lung dose reduction does not improve hematopoietic cell homing to BM during allogeneic transplantationA K Singh
Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Bone Marrow Transplant 45:25-30. 2010..TBI does not improve the homing of lineage-negative donor BM cells to the recipient marrow. The homing of lineage-negative, Kit-positive donor BM cells was significantly worse following TBI, with or without lung dose reduction... - Pretreatment nutritional status and locoregional failure of patients with head and neck cancer undergoing definitive concurrent chemoradiation therapyMary E Platek
Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA
Head Neck 33:1561-8. 2011.... - Intrarectal amifostine during external beam radiation therapy for prostate cancer produces significant improvements in Quality of Life measured by EPIC scoreNicole L Simone
Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Int J Radiat Oncol Biol Phys 70:90-5. 2008..To test whether intrarectal amifostine limits symptoms of radiation proctitis, measured by using the Radiation Therapy Oncology Group (RTOG) gastrointestinal (GI) toxicity score and the Expanded Prostate Cancer Index Composite (EPIC) score... - Early observed transient prostate-specific antigen elevations on a pilot study of external beam radiation therapy and fractionated MRI guided high dose rate brachytherapy boostAnurag K Singh
Radiation Oncology Branch, National Cancer Institute, NIH DHHS, Bldg 10, CRC Rm B2 3561, 9000 Rockville Pike, Bethesda, MD 20892, USA
Radiat Oncol 1:28. 2006..To report early observation of transient PSA elevations on this pilot study of external beam radiation therapy and magnetic resonance imaging (MRI) guided high dose rate (HDR) brachytherapy boost... - Radiation treatment interruptions greater than one week and low hemoglobin levels (12 g/dL) are predictors of local regional failure after definitive concurrent chemotherapy and intensity-modulated radiation therapy for squamous cell carcinoma of the headSusan A McCloskey
Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA
Am J Clin Oncol 32:587-91. 2009.... - Molecular and clinical responses in a pilot study of gefitinib with paclitaxel and radiation in locally advanced head-and-neck cancerCarter Van Waes
Head and Neck Surgery Branch, National Institute of Deafness and Communication Disorders, National Institutes of Health, Bethesda, MD, USA
Int J Radiat Oncol Biol Phys 77:447-54. 2010.... - Simultaneous integrated boost of biopsy proven, MRI defined dominant intra-prostatic lesions to 95 Gray with IMRT: early results of a phase I NCI studyAnurag K Singh
Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, USA
Radiat Oncol 2:36. 2007..To assess the feasibility and early toxicity of selective, IMRT-based dose escalation (simultaneous integrated boost) to biopsy proven dominant intra-prostatic lesions visible on MRI... - Efficacy of CD34+ stem cell dose in patients undergoing allogeneic peripheral blood stem cell transplantation after total body irradiationAnurag K Singh
Radiation Oncology Branch, National Cancer Institute, Bethesda, Maryland 20892, USA
Biol Blood Marrow Transplant 13:339-44. 2007..A method for assessing risk of mortality by CD34(+) dose as a continuous variable is presented. Risk of mortality decreased with CD34(+) doses between 4-8 x 10(6) cells/kg and then began to increase... - Improved survival following surgery and radiation therapy for olfactory neuroblastoma: analysis of the SEER databaseMary E Platek
Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA
Radiat Oncol 6:41. 2011..Olfactory Neuroblastoma is a rare malignant tumor of the olfactory tract. Reports in the literature comparing treatment modalities for this tumor are limited... - A second transient prostate-specific antigen elevation after external-beam radiation therapy and fractionated magnetic resonance imaging-guided high-dose rate brachytherapy boostMark V Mishra
Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Clin Genitourin Cancer 5:406-8. 2007.... - High incidence of oral dysesthesias on a trial of gefitinib, Paclitaxel, and concurrent external beam radiation for locally advanced head and neck cancersHadley Sharp
Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA
Am J Clin Oncol 31:557-60. 2008.... - Nicotinic modulation of therapeutic response in vitro and in vivoGraham W Warren
Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Int J Cancer 131:2519-27. 2012..These findings imply that during tobacco use, nicotine may function as a systemic agent through acute and reversible regulation of HIF-1α expression and a decreased therapeutic response... - Pretreatment predictors of death from other causes in men with prostate cancerNicole L Simone
Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
J Urol 180:2447-51; discussion 2451-2. 2008..Accurate stratification of patients by risk of other cause mortality may reduce needless treatment preventing morbidity and expense... - Pretransplant pulmonary function tests predict risk of mortality following fractionated total body irradiation and allogeneic peripheral blood stem cell transplantAnurag K Singh
Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Int J Radiat Oncol Biol Phys 66:520-7. 2006..To determine the value of pulmonary function tests (PFTs) done before peripheral blood stem cell transplant (PBSCT) in predicting mortality after total body irradiation (TBI) performed with or without dose reduction to the lung... - A prospective study of differences in duodenum compared to remaining small bowel motion between radiation treatments: implications for radiation dose escalation in carcinoma of the pancreasAnurag K Singh
Radiation Oncology Branch, National Cancer Institute, Bethesda, MD 20892, USA
Radiat Oncol 1:33. 2006..As a foundation for a dose escalation trial, we sought to characterize duodenal and non-duodenal small bowel organ motion between fractions of pancreatic radiation therapy... - Intrarectal amifostine suspension may protect against acute proctitis during radiation therapy for prostate cancer: a pilot studyAnurag K Singh
Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Int J Radiat Oncol Biol Phys 65:1008-13. 2006..1 g amifostine suspension. Further studies should be conducted in populations at higher risk for developing symptomatic acute and late proctitis... - Increased risk of bone loss without fracture risk in long-term survivors after allogeneic stem cell transplantationBipin N Savani
Stem Cell Allogeneic Transplantation Section, Hematology Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892 1202, USA
Biol Blood Marrow Transplant 13:517-20. 2007..Our data shows that BL is a long-term posttransplant complication, and emphasize the importance of serial BMD scans, and the treatment of BL with biphosphonates reserved for worsening BL or additional risk factors... - Quantification of incidental mediastinal and hilar irradiation delivered during definitive stereotactic body radiation therapy for peripheral non-small cell lung cancerKate L Martin
Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Med Dosim 37:182-5. 2012..Treatment of peripheral upper lobe lung tumors delivers less incidental irradiation to the paratracheal lymph nodes with lower likelihood of therapeutic benefit... - Accuracy of self-reported tobacco assessments in a head and neck cancer treatment populationGraham W Warren
Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Radiother Oncol 103:45-8. 2012..Accuracy increased by 14.9% with weekly vs. baseline self-reported assessments. Data confirm that head and neck cancer patients misrepresent true tobacco use during treatment... - Hope for progress after 40 years of futility? Novel approaches in the treatment of advanced stage III and IV non-small-cell-lung cancer: Stereotactic body radiation therapy, mediastinal lymphadenectomy, and novel systemic therapySimon Fung Fee Fung
Department of Radiation Medicine, Roswell Park Cancer Institute, University at Buffalo School of Medicine, Elm and Carlton Streets, Buffalo, New York, 14263, USA
J Carcinog 11:20. 2012..The utility of these techniques in advanced stage therapy and potential methods of combining these novel techniques with systemic therapy to improve survival are discussed... - Mild elevation of body temperature reduces tumor interstitial fluid pressure and hypoxia and enhances efficacy of radiotherapy in murine tumor modelsArindam Sen
Department of Immunology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
Cancer Res 71:3872-80. 2011..These data suggest, for the first time, that environmental manipulation of normal vasomotor function is capable of achieving therapeutically beneficial changes in IFP and microvascular function in the tumor microenvironment... - Treatment of early-stage uterine papillary serous carcinoma at Roswell Park Cancer Institute, 1992-2006Nana E Tchabo
Division of Gynecologic Oncology, Department of Surgery, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Gynecol Oncol 115:249-56. 2009..Optimal management of early-stage uterine papillary serous carcinoma (UPSC) remains controversial. We reviewed our outcomes in this patient population... - Alkaline phosphatase level increase with initiation of hormone therapy for prostate cancer portends poor prognosis with rapid progression to bone metastases: a case report and review of the literatureMichael W Brown
National Institutes of Health/National Cancer Institute, Bethesda, MD 20892, USA
Clin Genitourin Cancer 4:293-5. 2006..In this report, we explore the role of serum ALP as an indicator for patients who develop early metastases and thus might benefit from early initiation of aggressive secondary treatments such as chemotherapy... - Closed-loop control in fused MR-TRUS image-guided prostate biopsySheng Xu
Philips Research North America, Briarcliff, NY 10510, USA
Med Image Comput Comput Assist Interv 10:128-35. 2007..The accuracy of the system is 2.3 +/- 0.9 mm in phantom studies. The results of twelve patient studies show that prostate motion can be effectively compensated using closed-loop control... - Design and preliminary accuracy studies of an MRI-guided transrectal prostate intervention systemAxel Krieger
Department of Mechanical Engineering, Johns Hopkins University, Baltimore, USA
Med Image Comput Comput Assist Interv 10:59-67. 2007..Moreover, the portable design of the system using only standard MRI image sequences and minimal custom scanner interfacing allows the system to be easily used on different MRI scanners...