Thomas M Nicotera

Summary

Affiliation: Roswell Park Cancer Institute
Country: USA

Publications

  1. pmc The caspase pathway in noise-induced apoptosis of the chinchilla cochlea
    Thomas M Nicotera
    Molecular and Cellular Biophysics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    J Assoc Res Otolaryngol 4:466-77. 2003
  2. ncbi request reprint F-actin cleavage in apoptotic outer hair cells in chinchilla cochleas exposed to intense noise
    Bo Hua Hu
    Center for Hearing and Deafness, Department of Communicative Disorders and Sciences, State University of New York at Buffalo, 215 Parker Hall, 3435 Main Street, Buffalo, NY 14214, USA
    Hear Res 172:1-9. 2002
  3. ncbi request reprint Extremely rapid induction of outer hair cell apoptosis in the chinchilla cochlea following exposure to impulse noise
    Bo Hua Hu
    Center for Hearing and Deafness, Department of Communicative Disorders and Sciences, State University of New York at Buffalo, 137 Cary Hall, 3435 Main Street, Buffalo, NY 14214, USA
    Hear Res 211:16-25. 2006
  4. ncbi request reprint Quantitative analysis of apoptotic and necrotic outer hair cells after exposure to different levels of continuous noise
    Wei Ping Yang
    Center for Hearing and Deafness, State University of New York at Buffalo, 137 Cary Hall, 3435 Main Street, Buffalo, NY 14214, USA
    Hear Res 196:69-76. 2004
  5. ncbi request reprint Involvement of apoptosis in progression of cochlear lesion following exposure to intense noise
    Bo Hua Hu
    Center for Hearing and Deafness, Department of Communicative Disorders and Sciences, State University of New York at Buffalo, 215 Parker Hall, 3435 Main Street, Buffalo, NY 14214, USA
    Hear Res 166:62-71. 2002

Research Grants

  1. Cell Death Mechanisms of Noise-Induced Hearing Loss
    Thomas Nicotera; Fiscal Year: 2002

Detail Information

Publications5

  1. pmc The caspase pathway in noise-induced apoptosis of the chinchilla cochlea
    Thomas M Nicotera
    Molecular and Cellular Biophysics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    J Assoc Res Otolaryngol 4:466-77. 2003
    ..Lastly, use of the TUNEL assay in combination with PI labeling provides a more accurate discrimination between apoptosis and necrosis...
  2. ncbi request reprint F-actin cleavage in apoptotic outer hair cells in chinchilla cochleas exposed to intense noise
    Bo Hua Hu
    Center for Hearing and Deafness, Department of Communicative Disorders and Sciences, State University of New York at Buffalo, 215 Parker Hall, 3435 Main Street, Buffalo, NY 14214, USA
    Hear Res 172:1-9. 2002
    ..The results of this study indicate that F-actin cleavage is an important early cellular event in apoptotic development in OHCs following exposure to traumatic noise...
  3. ncbi request reprint Extremely rapid induction of outer hair cell apoptosis in the chinchilla cochlea following exposure to impulse noise
    Bo Hua Hu
    Center for Hearing and Deafness, Department of Communicative Disorders and Sciences, State University of New York at Buffalo, 137 Cary Hall, 3435 Main Street, Buffalo, NY 14214, USA
    Hear Res 211:16-25. 2006
    ..The results of the study demonstrate that induction of OHC apoptosis after the noise exposure is an extremely rapid process...
  4. ncbi request reprint Quantitative analysis of apoptotic and necrotic outer hair cells after exposure to different levels of continuous noise
    Wei Ping Yang
    Center for Hearing and Deafness, State University of New York at Buffalo, 137 Cary Hall, 3435 Main Street, Buffalo, NY 14214, USA
    Hear Res 196:69-76. 2004
    ..The results of the study indicate that the early expansion of cochlear lesion is attributed primarily to apoptosis, whereas the later stage of lesion expansion is likely the result of an equal contribution from apoptosis and necrosis...
  5. ncbi request reprint Involvement of apoptosis in progression of cochlear lesion following exposure to intense noise
    Bo Hua Hu
    Center for Hearing and Deafness, Department of Communicative Disorders and Sciences, State University of New York at Buffalo, 215 Parker Hall, 3435 Main Street, Buffalo, NY 14214, USA
    Hear Res 166:62-71. 2002
    ..These results clearly implicate the apoptotic pathway in the post-exposure progression of OHC demise...

Research Grants1

  1. Cell Death Mechanisms of Noise-Induced Hearing Loss
    Thomas Nicotera; Fiscal Year: 2002
    ..e. which takes place first). Collectively, these experiments will help better understand the molecular pathways involved in cell death and the results will serve as a rationale for future therapeutic intervention. ..