Philip L McCarthy

Summary

Affiliation: Roswell Park Cancer Institute
Country: USA

Publications

  1. doi request reprint Remestemcel-L for acute graft-versus-host disease therapy
    George L Chen
    Roswell Park Cancer Institute, Department of Medicine, BMT Program, Elm and Carlton Streets, Buffalo, NY 14263, USA 1 716 845 8412
    Expert Opin Biol Ther 14:261-9. 2014
  2. ncbi request reprint Part I: the role of maintenance therapy in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplantation
    Philip L McCarthy
    Blood and Marrow Transplant Program, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    J Natl Compr Canc Netw 11:35-42. 2013
  3. pmc Lenalidomide after stem-cell transplantation for multiple myeloma
    Philip L McCarthy
    Blood and Marrow Transplant Program, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    N Engl J Med 366:1770-81. 2012
  4. ncbi request reprint Histopathologic verification of acute leukemia (AL) in a cohort of 463 post-Chernobyl patients from Belarus, Russia and Ukraine
    Philip L McCarthy
    Department of Medicine, Blood and Marrow Transplant Section, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Leuk Res 28:1273-80. 2004
  5. pmc Influence of various factors on individual radiation exposure from the Chernobyl disaster
    Pavlo Zamostian
    National University Kyiv Mogila Academy Department of Environment Sciences, Kyiv, Ukraine
    Environ Health 1:4. 2002
  6. doi request reprint Granzyme B-mediated damage of CD8+ T cells impairs graft-versus-tumor effect
    Guanglin Bian
    Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    J Immunol 190:1341-50. 2013
  7. ncbi request reprint The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in adults: an evidence-based review
    Theresa Hahn
    Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 12:1-30. 2006
  8. doi request reprint Role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of pediatric acute lymphoblastic leukemia: update of the 2005 evidence-based review
    Denise M Oliansky
    Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 18:505-22. 2012
  9. pmc A comparison of HLA-identical sibling allogeneic versus autologous transplantation for diffuse large B cell lymphoma: a report from the CIBMTR
    Hillard M Lazarus
    Department of Medicine, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA
    Biol Blood Marrow Transplant 16:35-45. 2010
  10. doi request reprint Seeing what's out of sight: wireless capsule endoscopy's unique ability to visualize and accurately assess the severity of gastrointestinal graft-versus-host-disease
    Prakash Varadarajan
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 15:643-8. 2009

Detail Information

Publications47

  1. doi request reprint Remestemcel-L for acute graft-versus-host disease therapy
    George L Chen
    Roswell Park Cancer Institute, Department of Medicine, BMT Program, Elm and Carlton Streets, Buffalo, NY 14263, USA 1 716 845 8412
    Expert Opin Biol Ther 14:261-9. 2014
    ..There is a small market for remestemcel-L in aGvHD. A possible future scenario is that a more prevalent indication is found and remestemcel-L is approved for that indication, but use continues for aGvHD. ..
  2. ncbi request reprint Part I: the role of maintenance therapy in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplantation
    Philip L McCarthy
    Blood and Marrow Transplant Program, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    J Natl Compr Canc Netw 11:35-42. 2013
    ..Introduction of new therapies, alone or in combination with existing agents, may lead to increased improvement and prolongation of disease control after autologous hematopoietic stem cell transplantation for transplant-eligible patients...
  3. pmc Lenalidomide after stem-cell transplantation for multiple myeloma
    Philip L McCarthy
    Blood and Marrow Transplant Program, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    N Engl J Med 366:1770-81. 2012
    ..Data are lacking on whether lenalidomide maintenance therapy prolongs the time to disease progression after autologous hematopoietic stem-cell transplantation in patients with multiple myeloma...
  4. ncbi request reprint Histopathologic verification of acute leukemia (AL) in a cohort of 463 post-Chernobyl patients from Belarus, Russia and Ukraine
    Philip L McCarthy
    Department of Medicine, Blood and Marrow Transplant Section, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Leuk Res 28:1273-80. 2004
    ..Among the non-slide cases, 79% were confirmed as AL: 84% ALL, and 71% AML. This study affirms AL diagnostic accuracy during a time of social upheaval in the former Soviet Union...
  5. pmc Influence of various factors on individual radiation exposure from the Chernobyl disaster
    Pavlo Zamostian
    National University Kyiv Mogila Academy Department of Environment Sciences, Kyiv, Ukraine
    Environ Health 1:4. 2002
    ..This article presents a description of how historical events conspired to disrupt these efforts and affect residents in exposed areas...
  6. doi request reprint Granzyme B-mediated damage of CD8+ T cells impairs graft-versus-tumor effect
    Guanglin Bian
    Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    J Immunol 190:1341-50. 2013
    ..This study suggests that inhibiting donor-derived GzmB function may represent a promising strategy to improve GVT effect without exacerbating graft-versus-host disease...
  7. ncbi request reprint The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in adults: an evidence-based review
    Theresa Hahn
    Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 12:1-30. 2006
    ....
  8. doi request reprint Role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of pediatric acute lymphoblastic leukemia: update of the 2005 evidence-based review
    Denise M Oliansky
    Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 18:505-22. 2012
    ..Treatment recommendations pertaining to various transplantation techniques are also provided, as are areas of needed future research...
  9. pmc A comparison of HLA-identical sibling allogeneic versus autologous transplantation for diffuse large B cell lymphoma: a report from the CIBMTR
    Hillard M Lazarus
    Department of Medicine, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA
    Biol Blood Marrow Transplant 16:35-45. 2010
    ....
  10. doi request reprint Seeing what's out of sight: wireless capsule endoscopy's unique ability to visualize and accurately assess the severity of gastrointestinal graft-versus-host-disease
    Prakash Varadarajan
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 15:643-8. 2009
    ..WCE is an excellent, noninvasive method for assessing GI GVHD, with the ability to more accurately assess the severity of GVHD, evaluate clinical symptoms, and follow response to treatment...
  11. doi request reprint The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of diffuse large B cell lymphoma: update of the 2001 evidence-based review
    Denise M Oliansky
    Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 17:20-47.e30. 2011
    ..Areas of needed research in the treatment of DLBCL with SCT were identified and are presented in the review...
  12. pmc Risk factors for acute graft-versus-host disease after human leukocyte antigen-identical sibling transplants for adults with leukemia
    Theresa Hahn
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    J Clin Oncol 26:5728-34. 2008
    ..No large registry studies of acute GVHD risk factors have been reported in two decades. Risk factors may have changed in this interval as transplant-related techniques have evolved...
  13. pmc Trends in use of and survival after autologous hematopoietic cell transplantation in North America, 1995-2005: significant improvement in survival for lymphoma and myeloma during a period of increasing recipient age
    Philip L McCarthy
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY, USA
    Biol Blood Marrow Transplant 19:1116-23. 2013
    ..001) and chemotherapy-sensitive multiple myeloma (day +100 OS, from 96% to 98%; 1-year OS, from 83% to 92%; P < .001). This improvement in OS was most pronounced in middle-aged (>40 years) and older (>60 years) individuals...
  14. ncbi request reprint The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute myeloid leukemia in children: an evidence-based review
    Denise M Oliansky
    Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 13:1-25. 2007
    ..What is the role of biologically targeted agents (ie, tyrosine kinase inhibitors, farnesyl transferase inhibitors, Flt-3 inhibitors, etc) in the treatment of AML, including induction, consolidation, conditioning regimens, and after SCT?..
  15. ncbi request reprint Invasive filamentous fungal infections in allogeneic hematopoietic stem cell transplant recipients after recovery from neutropenia: clinical, radiologic, and pathologic characteristics
    Aasma Shaukat
    Department of Medicine, School of Medicine and Biochemical Sciences, SUNY at Buffalo, Buffalo 14263, NY, USA
    Mycopathologia 159:181-8. 2005
    ..The predominance of coagulative necrosis in our series may reflect the high doses of corticosteroids used to treat graft-versus-host disease (GVHD), which may have disabled leukocyte trafficking and hyphal killing...
  16. pmc Influence of age and histology on outcome in adult non-Hodgkin lymphoma patients undergoing autologous hematopoietic cell transplantation (HCT): a report from the Center For International Blood & Marrow Transplant Research (CIBMTR)
    Hillard M Lazarus
    Department of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    Biol Blood Marrow Transplant 14:1323-33. 2008
    ..Studies addressing supportive care particular to older patients, who are most likely to benefit from this approach, are recommended...
  17. pmc Common genetic variants are associated with accelerated bone mineral density loss after hematopoietic cell transplantation
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, United States of America
    PLoS ONE 6:e25940. 2011
    ..Hypothesizing that genetic variants may influence post-HCT BMD loss, we conducted a prospective study to examine the associations of single nucleotide polymorphisms (SNP) in bone metabolism pathways and acute BMD loss after HCT...
  18. doi request reprint The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of adult acute lymphoblastic leukemia: update of the 2006 evidence-based review
    Denise M Oliansky
    Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 18:18-36.e6. 2012
    ..Areas of needed research in the treatment of adult ALL with SCT were identified and presented in the review...
  19. ncbi request reprint Ganciclovir inhibits lymphocyte proliferation by impairing DNA synthesis
    Minoo Battiwalla
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14202, USA
    Biol Blood Marrow Transplant 13:765-70. 2007
    ..Collectively, these results show that ganciclovir suppresses T-lymphocyte proliferation in vitro by inhibiting DNA synthesis; with implications for T-lymphocyte function following allogeneic BMT...
  20. doi request reprint A deletion polymorphism in glutathione-S-transferase mu (GSTM1) and/or theta (GSTT1) is associated with an increased risk of toxicity after autologous blood and marrow transplantation
    Theresa Hahn
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 16:801-8. 2010
    ..034) and mucositis (74% versus 55%, P = .006). GSTM1 and/or GSTT1 deletion polymorphisms were not associated with toxicity after allogeneic BMT. Future studies may allow for individualized genetic risk stratification...
  21. pmc The Chernobyl childhood leukemia study: background & lessons learned
    Martin C Mahoney
    Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Carlton and Elm Streets, Buffalo, NY 14263, USA
    Environ Health 3:12. 2004
    ..In an era of globalization, our experiences might benefit others involved in multinational investigations...
  22. ncbi request reprint Human leukocyte antigen (HLA) DR15 is associated with reduced incidence of acute GVHD in HLA-matched allogeneic transplantation but does not impact chronic GVHD incidence
    Minoo Battiwalla
    Department of Medicine and Laboratory Medicine, Blood and Marrow Transplantation, Roswell Park Cancer Institute, Buffalo, NY 14202, USA
    Blood 107:1970-3. 2006
    ..The HLA DR15-positive group experienced a significantly lower incidence of acute GVHD grades II to IV: 23% versus 42% (P = .041). These results suggest that HLA DR15 reduces the risk of acute GVHD...
  23. doi request reprint The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute myelogenous leukemia in adults: an evidence-based review
    Denise M Oliansky
    Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 14:137-80. 2008
    ..conventional conditioning in older (>60 years) and intermediate (40-60 years) aged adults? (4) What is the impact on survival outcomes of unrelated donor HSCT vesus chemotherapy in younger (<40 years) adults with high risk disease?..
  24. doi request reprint Human leukocyte antigen DR4 is associated with inferior progression-free survival following allogeneic hematopoietic stem cell transplantation for lymphoid malignancies
    Charu Aggarwal
    Department of Medicine, School of Medicine and Biochemical Sciences, State University of New York at Buffalo, Buffalo, NY, USA
    Leuk Lymphoma 49:1494-500. 2008
    ..2, p = 0.007). Our results suggest that in addition to the known role of HLA DRB1 disparity in mediating histocompatibility, HLA DR4 is associated with inferior PFS in patients with lymphoid malignancy undergoing alloHSCT...
  25. doi request reprint Accelerated bone mineral density loss occurs with similar incidence and severity, but with different risk factors, after autologous versus allogeneic hematopoietic cell transplantation
    Song Yao
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 16:1130-7. 2010
    ..Evaluation of clinical strategies to prevent and reverse HCT-related BMD loss is necessary in both autologous and allogeneic HCT patients...
  26. doi request reprint A TLR5 agonist enhances CD8(+) T cell-mediated graft-versus-tumor effect without exacerbating graft-versus-host disease
    Xilai Ding
    Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    J Immunol 189:4719-27. 2012
    ..This study demonstrates a new beneficial effect of CBLB502, and suggests that TLR5-mediated immune modulation may be a promising approach to improve GVT immunity without exacerbating graft-versus-host disease...
  27. ncbi request reprint Chronic myeloid leukemia after treatment of lymphoid malignancies: response to imatinib mesylate and favorable outcomes in three patients
    Jeyanthi Ramanarayanan
    Department of Medicine, Roswell Park Cancer Institute, State University of New York, Buffalo, NY 14263, USA
    Leuk Res 30:701-5. 2006
    ..All three patients received imatinib therapy, with one patient subsequently undergoing allogeneic hematopoietic stem cell transplantation. All three patients have ongoing favorable responses to CML therapy...
  28. doi request reprint The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of follicular lymphoma: an evidence-based review
    Denise M Oliansky
    Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Biol Blood Marrow Transplant 16:443-68. 2010
    ..Eleven areas of needed research in the treatment of follicular lymphoma with SCT were identified and are presented in the review...
  29. doi request reprint Simplified validated prognostic model for progression-free survival after autologous transplantation for hodgkin lymphoma
    Theresa Hahn
    Division of Blood and Marrow Transplant, Roswell Park Cancer Institute, Buffalo, New York
    Biol Blood Marrow Transplant 19:1740-4. 2013
    ..This model should assist in the prospective evaluation of alternative treatment strategies...
  30. ncbi request reprint The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in children: an evidence-based review
    Theresa Hahn
    Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 11:823-61. 2005
    ....
  31. doi request reprint A comparison of measured creatinine clearance versus calculated glomerular filtration rate for assessment of renal function before autologous and allogeneic BMT
    Theresa Hahn
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 15:574-9. 2009
    ..Larger analyses and transplantation of patients with GFR <50 mL/min may better define subgroups at risk for renal RRT...
  32. doi request reprint The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of myelodysplastic syndromes: an evidence-based review
    Denise M Oliansky
    Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 15:137-72. 2009
    ....
  33. ncbi request reprint Progressive chronic lymphocytic leukemia after allogeneic hematopoietic cell transplantation
    Potjana Jitawatanarat
    Department of Medicine, BMT Program, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    J Natl Compr Canc Netw 10:1203-6. 2012
    ..The application of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for CLL and the impact of alloHCT on secondary therapy for progressive CLL are discussed...
  34. ncbi request reprint Long-term use of oral beclomethasone dipropionate for the treatment of gastrointestinal graft-versus-host disease
    Renuka V Iyer
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 11:587-92. 2005
    ..Multiple courses may be necessary to achieve or maintain response in some patients, and prolonged BDP therapy is a feasible alternative to prolonged systemic corticosteroids...
  35. doi request reprint Unrelated donor allogeneic hematopoietic cell transplantation is underused as a curative therapy in eligible patients from the United States
    Song Yao
    Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York
    Biol Blood Marrow Transplant 19:1459-64. 2013
    ..Understanding the reasons for low use of alloHCT may lead to strategies to expand the use of this curative therapy for more patients with hematologic disorders. ..
  36. ncbi request reprint The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of multiple myeloma: an evidence-based review
    Theresa Hahn
    Roswell Park Cancer Institute, Department of Medicine, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 9:4-37. 2003
    ..The priority area of needed future research is maintenance therapy posttransplantation with nothing versus interferon alpha versus other agents such as corticosteroids or thalidomide or its derivatives...
  37. pmc Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner
    Maegan L Capitano
    Departments of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Blood 120:2600-9. 2012
    ..These findings suggest that a physiologically relevant increase in body temperature can accelerate recovery from neutropenia after TBI through a G-CSF-, IL-17-, and IL-1-dependent mechanism...
  38. ncbi request reprint Adoptive immunotherapy by allogeneic stem cell transplantation for metastatic renal cell carcinoma: a CALGB intergroup phase II study
    Brian I Rini
    Department of Medicine, University of California San Francisco Cancer Center, San Francisco, California, USA
    Biol Blood Marrow Transplant 12:778-85. 2006
    ..A graft-versus-tumor effect was not observed in this study despite acute and chronic GVHD, thus highlighting the need for further understanding of this approach. Allogeneic SCT remains investigational in RCC...
  39. ncbi request reprint The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of diffuse large cell B-cell non-Hodgkin's lymphoma
    Theresa Hahn
    Roswell Park Cancer Institute, Buffalo, NY, USA
    Biol Blood Marrow Transplant 9:667. 2003
  40. pmc Multiparameter flow cytometry for the diagnosis and monitoring of small GPI-deficient cellular populations
    Minoo Battiwalla
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA
    Cytometry B Clin Cytom 78:348-56. 2010
    ..We studied the reliability of high-resolution flow cytometry markers operating at the limits of detection...
  41. ncbi request reprint Thyroid cancer incidence trends in Belarus: examining the impact of Chernobyl
    Martin C Mahoney
    Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Int J Epidemiol 33:1025-33. 2004
    ..While prior studies of thyroid cancer incidence within Belarus have increased since the 1986 Chernobyl reactor accident, the magnitude of increase is not well quantified...
  42. ncbi request reprint Thrombotic microangiopathy after allogeneic blood and marrow transplantation is associated with dose-intensive myeloablative conditioning regimens, unrelated donor, and methylprednisolone T-cell depletion
    Theresa Hahn
    Department of Medicine, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Transplantation 78:1515-22. 2004
    ..This report examines the incidence of and risk factors for allogeneic BMT-associated TM in two patient cohorts treated before and after changes in myeloablative conditioning regimen intensity (high vs. standard intensity)...
  43. ncbi request reprint Development of a pharmacokinetic and Bayesian optimal sampling model for individualization of oral busulfan in hematopoietic stem cell transplantation
    Julie M Bullock
    Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Ther Drug Monit 28:62-6. 2006
    ..All limited sampling models tested were unbiased in their results, and a 4-sample scheme proved to adequately characterize busulfan pharmacokinetics, and should allow for a reduced sampling frequency for therapeutic drug monitoring...
  44. pmc Second autologous stem cell transplantation for relapsed lymphoma after a prior autologous transplant
    Sonali M Smith
    Department of Medicine, The University of Chicago, Chicago, Illinois 60637, USA
    Biol Blood Marrow Transplant 14:904-12. 2008
    ..HCT2 should be considered for patients with relapsed HL or NHL after HCT1 without alternative allogeneic stem cell transplant options...
  45. doi request reprint The emerging role of consolidation and maintenance therapy for transplant-eligible multiple myeloma patients
    Philip L McCarthy
    Blood and Marrow Transplant Program, Roswell Park Cancer Institute, Buffalo, NY, USA
    Expert Rev Hematol 7:55-66. 2014
    ..Incorporation of new therapies in combination with existing agents should lead increased response and improved survival of the MM patient with the ultimate goal of development of curative approaches for this disease. ..
  46. doi request reprint Strategies for induction, autologous hematopoietic stem cell transplantation, consolidation, and maintenance for transplantation-eligible multiple myeloma patients
    Philip L McCarthy
    1Roswell Park Cancer Institute, BMT Program, Department of Medicine, Buffalo, NY
    Hematology Am Soc Hematol Educ Program 2013:496-503. 2013
    ..Incorporation of new agents into the continuum of multiple myeloma care should result in improved outcomes and long-term disease control. ..
  47. pmc Linezolid-resistant Enterococcus faecalis isolated from a cord blood transplant recipient
    Imad Dibo
    Department of Medicine, Roswell Park Cancer Institute, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York, USA
    J Clin Microbiol 42:1843-5. 2004
    ..Sequencing showed a G2576U mutation in the 23S rRNA gene. Because of the important niche of linezolid in cancer treatment, linezolid-resistant E. faecalis is noteworthy...