Brenda Lauffart

Summary

Affiliation: Roswell Park Cancer Institute
Country: USA

Publications

  1. pmc Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells
    Brenda Lauffart
    Department of Cancer Genetics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Biochem J 363:195-200. 2002
  2. ncbi request reprint The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases
    Omkaram Gangisetty
    Department of Cancer Genetics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Oncogene 23:2559-63. 2004
  3. ncbi request reprint Temporal and spatial expression of TACC1 in the mouse and human
    Brenda Lauffart
    Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Dev Dyn 235:1638-47. 2006
  4. ncbi request reprint Molecular cloning, genomic structure and interactions of the putative breast tumor suppressor TACC2
    Brenda Lauffart
    Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Genomics 81:192-201. 2003

Collaborators

Detail Information

Publications4

  1. pmc Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells
    Brenda Lauffart
    Department of Cancer Genetics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Biochem J 363:195-200. 2002
    ..This suggests that the TACC proteins can form multiple complexes, dysregulation of which may be an important step during tumorigenesis...
  2. ncbi request reprint The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases
    Omkaram Gangisetty
    Department of Cancer Genetics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Oncogene 23:2559-63. 2004
    ..This raises the possibility that aberrant expression of one or more TACC proteins may affect gene regulation through their interaction with components of chromatin remodeling complexes, thus contributing to tumorigenesis...
  3. ncbi request reprint Temporal and spatial expression of TACC1 in the mouse and human
    Brenda Lauffart
    Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Dev Dyn 235:1638-47. 2006
    ..Furthermore, this analysis will provide the groundwork from which future Tacc1 knockout strategies can be designed and properly interpreted...
  4. ncbi request reprint Molecular cloning, genomic structure and interactions of the putative breast tumor suppressor TACC2
    Brenda Lauffart
    Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Genomics 81:192-201. 2003
    ..Significantly, we demonstrate that TACC2 interacts with GAS41 and the SWI/SNF chromatin remodeling complex. This suggests that defects in TACC2 expression may affect gene regulation, thus contributing to the pathogenesis of some tumors...