Research Topics
Species | Renuka IyerSummaryAffiliation: Roswell Park Cancer Institute Country: USA Publications
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Detail Information
Publications
A phase II study of gemcitabine and capecitabine in advanced cholangiocarcinoma and carcinoma of the gallbladder: a single-institution prospective studyRenuka V Iyer
Department of Medical Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA
Ann Surg Oncol 14:3202-9. 2007..To determine the clinical benefit response (CBR), time to tumor progression (TTP), overall survival, and effect on quality of life (QOL) of gemcitabine and capecitabine in patients with advanced biliary cancer...- Long-term use of oral beclomethasone dipropionate for the treatment of gastrointestinal graft-versus-host diseaseRenuka V Iyer
Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
Biol Blood Marrow Transplant 11:587-92. 2005..Multiple courses may be necessary to achieve or maintain response in some patients, and prolonged BDP therapy is a feasible alternative to prolonged systemic corticosteroids... 
Sorafenib: a clinical and pharmacologic reviewRenuka Iyer
Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Expert Opin Pharmacother 11:1943-55. 2010..Sorafenib is approved for the treatment of advanced inoperable hepatocellular cancer and advanced renal cell cancer...- A review of erlotinib--an oral, selective epidermal growth factor receptor tyrosine kinase inhibitorRenuka Iyer
Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Expert Opin Pharmacother 11:311-20. 2010.... - Surgical resection after TNFerade therapy for locally advanced pancreatic cancerManpreet K Chadha
Department of Medicine, Roswell Park Cancer Institute and State University of New York at Buffalo, Buffalo, NY, USA
JOP 10:535-8. 2009..Transfection of tumor cells with TNFerade maximizes the antitumor effect of TNF-alpha under influence of radiation leading to synergistic effects in preclinical studies... - Metastatic pancreatic adenocarcinoma and renal cell carcinoma treated with gemcitabine and sunitinib malate. A case reportAnubha Bharthuar
Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
JOP 10:523-7. 2009..When present simultaneously, they pose a therapeutic challenge given the many available targeted agents with reported efficacy in renal cell cancer and limited options for metastatic pancreatic cancer... - Cyclooxygenase-2 (COX-2) levels before and after chemotherapy: a study in rectal cancerVeena Watwe
Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Am J Clin Oncol 28:560-4. 2005..CONCLUSIONS: COX-2 induction was seen with CRT in this population of rectal cancer patients. Prognostic significance of this induction remains to be defined in a larger cohort... - Combined hepatocholangiocarcinoma: case-series and review of literatureVishal Bhagat
Department of Medicine, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Int J Gastrointest Cancer 37:27-34. 2006..0357, one-sided exact log-rank test). CONCLUSIONS: Chronic inflammation and cirrhosis may play a role in pathogenesis of CHCC. Surgical resection and early stage at diagnosis predict longer survival... - Gallbladder cancer: Defining the indications for primary radical resection and radical re-resectionJason M Foster
Department of Surgical Oncology, Roswell Park Cancer Institute, State University of New York at Buffalo, Elm and Carlton Streets, Buffalo, New York 14263 0001, USA
Ann Surg Oncol 14:833-40. 2007..In this review, we present our experience managing gallbladder cancer at a tertiary center by using an aggressive surgical approach for T2 or greater disease, reserving simple cholecystectomy only for T1 lesions... - Cystic pancreatic tumors (CPT): predictors of malignant behaviorMilind Javle
Department of Medicine, Roswell Park Cancer Institute, and State University at Buffalo, Buffalo, New York 14263, USA
J Surg Oncol 95:221-8. 2007..The diagnosis of malignancy in CPT cases requires pancreatectomy. Clinical and laboratory characteristics of CPT may predict underlying malignancy... - Exact tests using two correlated binomial variables in contemporary cancer clinical trialsJihnhee Yu
Department of Biostatistics, University at Buffalo, State University of New York, Buffalo, NY, USA
Biom J 51:899-914. 2009..The method is easy to implement. It does not increase the sample size over that of the univariate exact test and in most cases reduces the sample size required. Sample size calculations are provided for selected designs... - Chemoradiation is a tolerable therapy for older adults with esophageal cancerSujatha Nallapareddy
Roswell Park Cancer Institute, Elm and Carlton Sts, Buffalo, NY 14263, USA
Anticancer Res 25:3055-60. 2005..The median survival of the patients was 10 months. CONCLUSION: CRT was tolerable for older patients with EC. Close monitoring for dehydration, nutritional compromise and pulmonary toxicity is required... 
Evaluation of phosphatidylinositol-3-kinase catalytic subunit (PIK3CA) and epidermal growth factor receptor (EGFR) gene mutations in pancreaticobiliary adenocarcinomaGuy A Weiss
Department of Medicine, University at Buffalo, Buffalo, New York, USA
J Gastrointest Oncol 4:20-9. 2013..This study examined the prevalence of PIK3CA and EGFR mutations in pancreaticobiliary cancer where erlotinib, an EGFR inhibitor, is approved for therapy...- Higher Frequencies of GARP+CTLA-4+Foxp3+ T Regulatory Cells and Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Are Associated with Impaired T-Cell FunctionalitySuresh Kalathil
Authors Affiliations Departments of Immunology, Biostatistics, and Medicine, Roswell Park Cancer Institute, Buffalo, New York
Cancer Res 73:2435-44. 2013..Cancer Res; 73(8); 2435-44. ©2013 AACR... - Leptomeningeal metastases from signet ring adenocarcinoma of the cecumManpreet K Chadha
Department of Medicine, State University of New York, Buffalo and Roswell Park Cancer Institute, Buffalo, NY, USA
J Clin Oncol 25:5028-9. 2007 - Expression of intestinal trefoil factor (TFF-3) in hepatocellular carcinomaThaer Khoury
Department of Pathology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Int J Gastrointest Cancer 35:171-7. 2005..Intestinal trefoil peptide (TFF-3) expression has been demonstrated in benign hepatobiliary diseases, but there are limited data regarding its expression in HCC... - Anaplastic pancreatic carcinoma. A case report and review of literature Manpreet K Chadha
Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
JOP 5:512-5. 2004..A brief review of the histological and radiological findings and the possible mechanisms of the pathogenesis of anaplastic tumors is included in the discussion... - Scheduled administration of low dose irinotecan before gemcitabine in the second line therapy of non-small cell lung cancer: a phase II studyNithya Ramnath
Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Anticancer Drugs 19:749-52. 2008..However, this approach was associated with higher grade 3/4 neutropenia and is not recommended for further study in metastatic NSCLC... - Celecoxib and mucosal protection: translation from an animal model to a phase I clinical trial of celecoxib, irinotecan, and 5-fluorouracilMilind M Javle
Department of Gastrointestinal Medical Oncology, The University of Texas M D Anderson Cancer Institute, Houston, Texas 77030, USA
Clin Cancer Res 13:965-71. 2007..Cyclooxygenase-2 inhibitors may ameliorate chemotherapy-induced mucosal toxicity and enhance its antitumor effect. We investigated this hypothesis in the Ward colorectal cancer rat model and in a phase I clinical study... - Akt expression may predict favorable prognosis in cholangiocarcinomaMilind M Javle
Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
J Gastroenterol Hepatol 21:1744-51. 2006..The aim of this clinicopathological study was to investigate the overexpression and co-expression of EGFR and related signaling proteins in cholangiocarcinoma and explore their relationship to clinical outcome...