Barbara Henderson

Summary

Affiliation: Roswell Park Cancer Institute
Country: USA

Publications

  1. pmc Role of cytokines in photodynamic therapy-induced local and systemic inflammation
    S O Gollnick
    PDT Center, Roswell Park Cancer Institute, Elm and Carlton St, Buffalo, NY 14263, USA
    Br J Cancer 88:1772-9. 2003
  2. ncbi request reprint Fluence rate as a modulator of PDT mechanisms
    Barbara W Henderson
    Department of Cell Stress Biology, The Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo, New York, New York 14263, USA
    Lasers Surg Med 38:489-93. 2006
  3. ncbi request reprint Choice of oxygen-conserving treatment regimen determines the inflammatory response and outcome of photodynamic therapy of tumors
    Barbara W Henderson
    Department of Cellular Stress Biology and the Photodynamic Therapy Center, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Cancer Res 64:2120-6. 2004
  4. doi request reprint Adjuvant intraoperative photodynamic therapy in head and neck cancer
    Nestor R Rigual
    Department of Head and Neck Surgery, Roswell Park Cancer Institute, Buffalo, New York, USA
    JAMA Otolaryngol Head Neck Surg 139:706-11. 2013
  5. pmc Photodynamic therapy for head and neck dysplasia and cancer
    Nestor R Rigual
    Department of Head and Neck Surgery Plastic and Reconstructive Surgery, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Arch Otolaryngol Head Neck Surg 135:784-8. 2009
  6. ncbi request reprint Endobronchial photodynamic therapy for lung cancer
    Gregory M Loewen
    Solid Tumor Division, Department of Medicine, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York 14263, USA
    Lasers Surg Med 38:364-70. 2006
  7. ncbi request reprint Photodynamic therapy: a means to enhanced drug delivery to tumors
    John W Snyder
    The Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Cancer Res 63:8126-31. 2003
  8. pmc Light delivery over extended time periods enhances the effectiveness of photodynamic therapy
    Mukund Seshadri
    Department of Cell Stress Biology and Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Clin Cancer Res 14:2796-805. 2008
  9. ncbi request reprint Generation of effective antitumor vaccines using photodynamic therapy
    Sandra O Gollnick
    PDT Center, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Cancer Res 62:1604-8. 2002
  10. pmc Photodynamic therapy enhancement of antitumor immunity is regulated by neutrophils
    Philaretos C Kousis
    Department of Cell Stress Biology and the Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Cancer Res 67:10501-10. 2007

Research Grants

  1. OXYGEN AND LIGHT DEPENDENCY OF PHOTODYNAMIC THERAPY
    Barbara Henderson; Fiscal Year: 2000
  2. OXYGEN AND LIGHT DEPENDENCY OF PHOTODYNAMIC THERAPY
    Barbara Henderson; Fiscal Year: 2001
  3. OXYGEN AND LIGHT DEPENDENCY OF PHOTODYNAMIC THERAPY
    Barbara Henderson; Fiscal Year: 2002
  4. OXYGEN AND LIGHT DEPENDENCY OF PHOTODYNAMIC THERAPY
    Barbara Henderson; Fiscal Year: 2003
  5. OXYGEN AND LIGHT DEPENDENCY OF PHOTODYNAMIC THERAPY
    Barbara Henderson; Fiscal Year: 2004

Collaborators

Detail Information

Publications15

  1. pmc Role of cytokines in photodynamic therapy-induced local and systemic inflammation
    S O Gollnick
    PDT Center, Roswell Park Cancer Institute, Elm and Carlton St, Buffalo, NY 14263, USA
    Br J Cancer 88:1772-9. 2003
    ..They also lay the mechanistic groundwork for further ongoing studies that attempt to optimise PDT through the modulation of the critical inflammatory mediators...
  2. ncbi request reprint Fluence rate as a modulator of PDT mechanisms
    Barbara W Henderson
    Department of Cell Stress Biology, The Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo, New York, New York 14263, USA
    Lasers Surg Med 38:489-93. 2006
    ..This article provides supporting evidence for the role of fluence rate in PDT and discusses the underlying mechanisms...
  3. ncbi request reprint Choice of oxygen-conserving treatment regimen determines the inflammatory response and outcome of photodynamic therapy of tumors
    Barbara W Henderson
    Department of Cellular Stress Biology and the Photodynamic Therapy Center, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Cancer Res 64:2120-6. 2004
    ..Local inflammation is not a critical factor for tumor control under optimal PDT treatment conditions...
  4. doi request reprint Adjuvant intraoperative photodynamic therapy in head and neck cancer
    Nestor R Rigual
    Department of Head and Neck Surgery, Roswell Park Cancer Institute, Buffalo, New York, USA
    JAMA Otolaryngol Head Neck Surg 139:706-11. 2013
    ..There is an immediate need to develop local intraoperative adjuvant treatment strategies to improve outcomes in patients with cancer who undergo head and neck surgery...
  5. pmc Photodynamic therapy for head and neck dysplasia and cancer
    Nestor R Rigual
    Department of Head and Neck Surgery Plastic and Reconstructive Surgery, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Arch Otolaryngol Head Neck Surg 135:784-8. 2009
    ..To determine the response of dysplasia, carcinoma in situ (CIS), and T1 carcinoma of the oral cavity and larynx to photodynamic therapy with porfimer sodium...
  6. ncbi request reprint Endobronchial photodynamic therapy for lung cancer
    Gregory M Loewen
    Solid Tumor Division, Department of Medicine, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York 14263, USA
    Lasers Surg Med 38:364-70. 2006
    ..Endobronchial photodynamic therapy (PDT) is a minimally invasive technique for the palliation of major airway obstruction from lung cancer, and for the treatment of endobronchial microinvasive lung cancer...
  7. ncbi request reprint Photodynamic therapy: a means to enhanced drug delivery to tumors
    John W Snyder
    The Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Cancer Res 63:8126-31. 2003
    ..In summary, we have developed a novel PDT treatment that enhances the delivery and efficacy of macromolecule-based cancer therapies such as Doxil...
  8. pmc Light delivery over extended time periods enhances the effectiveness of photodynamic therapy
    Mukund Seshadri
    Department of Cell Stress Biology and Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Clin Cancer Res 14:2796-805. 2008
    ..The objective of this study was to investigate the relationship between irradiance, photosensitizer dose, and PDT dose with regard to treatment outcome and tumor oxygenation in a rat tumor model...
  9. ncbi request reprint Generation of effective antitumor vaccines using photodynamic therapy
    Sandra O Gollnick
    PDT Center, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Cancer Res 62:1604-8. 2002
    ..These studies also suggest that in addition to the role of PDT as a therapeutic modality, PDT-generated vaccines may have clinical potential as an adjuvant therapy...
  10. pmc Photodynamic therapy enhancement of antitumor immunity is regulated by neutrophils
    Philaretos C Kousis
    Department of Cell Stress Biology and the Photodynamic Therapy Center, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Cancer Res 67:10501-10. 2007
    ..Immune-enhancing PDT regimens may then be combined with treatments that result in optimal ablation of primary tumors, thus inhibiting growth of primary tumor and controlling disseminated disease...
  11. ncbi request reprint Cross-linking of signal transducer and activator of transcription 3--a molecular marker for the photodynamic reaction in cells and tumors
    Barbara W Henderson
    Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Clin Cancer Res 13:3156-63. 2007
    ..This study establishes a quantitative marker for the photoreaction that will predict the outcome of PDT...
  12. ncbi request reprint Purpurinimide carbohydrate conjugates: effect of the position of the carbohydrate moiety in photosensitizing efficacy
    Suresh K Pandey
    Photodynamic Therapy Center, Department of Dermatology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Mol Pharm 4:448-64. 2007
    ..In a comparative ELISA study of the lactose conjugates with free lactose, all carbohydrate-purpurinimides showed binding to both galectins with a significant variation between the batches of galectins...
  13. ncbi request reprint A novel approach to a bifunctional photosensitizer for tumor imaging and phototherapy
    Yihui Chen
    PDT Center, Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Bioconjug Chem 16:1264-74. 2005
    ....
  14. ncbi request reprint Synthesis and photosensitizing efficacy of isomerically pure bacteriopurpurinimides
    Yihui Chen
    PDT Center, Department of Dermatology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    J Med Chem 47:4814-7. 2004
    ..However, in preliminary in vivo screening, compared to the S-isomer, the corresponding R-isomer produced enhanced in vivo photodynamic therapy efficacy...
  15. ncbi request reprint Bacteriopurpurinimides: highly stable and potent photosensitizers for photodynamic therapy
    Yihui Chen
    J Med Chem 45:255-8. 2002
    ....

Research Grants5

  1. OXYGEN AND LIGHT DEPENDENCY OF PHOTODYNAMIC THERAPY
    Barbara Henderson; Fiscal Year: 2000
    ..Similarly, PDT destroyed tumor cells may provide tumor antigen to differentiating dendritic cells generated by preceding delivery of GM-CSF. ..
  2. OXYGEN AND LIGHT DEPENDENCY OF PHOTODYNAMIC THERAPY
    Barbara Henderson; Fiscal Year: 2001
    ..Similarly, PDT destroyed tumor cells may provide tumor antigen to differentiating dendritic cells generated by preceding delivery of GM-CSF. ..
  3. OXYGEN AND LIGHT DEPENDENCY OF PHOTODYNAMIC THERAPY
    Barbara Henderson; Fiscal Year: 2002
    ..Similarly, PDT destroyed tumor cells may provide tumor antigen to differentiating dendritic cells generated by preceding delivery of GM-CSF. ..
  4. OXYGEN AND LIGHT DEPENDENCY OF PHOTODYNAMIC THERAPY
    Barbara Henderson; Fiscal Year: 2003
    ..Similarly, PDT destroyed tumor cells may provide tumor antigen to differentiating dendritic cells generated by preceding delivery of GM-CSF. ..
  5. OXYGEN AND LIGHT DEPENDENCY OF PHOTODYNAMIC THERAPY
    Barbara Henderson; Fiscal Year: 2004
    ..Similarly, PDT destroyed tumor cells may provide tumor antigen to differentiating dendritic cells generated by preceding delivery of GM-CSF. ..