Laila Abdullah

Summary

Affiliation: Roskamp Institute
Country: USA

Publications

  1. ncbi request reprint Chronic elevation of phosphocholine containing lipids in mice exposed to Gulf War agents pyridostigmine bromide and permethrin
    Laila Abdullah
    Roskamp Institute, 2040 Whitfield Ave, Sarasota, FL 34243, United States Electronic address
    Neurotoxicol Teratol 40:74-84. 2013
  2. doi request reprint Lipidomic profiling of phosphocholine-containing brain lipids in mice with sensorimotor deficits and anxiety-like features after exposure to Gulf War agents
    Laila Abdullah
    Roskamp Institute, Sarasota, FL 34243, USA
    Neuromolecular Med 14:349-61. 2012
  3. ncbi request reprint The cyclooxygenase 2 -765 C promoter allele is a protective factor for Alzheimer's disease
    Laila Abdullah
    Roskamp Institute, 2040 Whitfield Ave Sarasota, FL, USA
    Neurosci Lett 395:240-3. 2006
  4. doi request reprint Proteomic CNS profile of delayed cognitive impairment in mice exposed to Gulf War agents
    Laila Abdullah
    Roskamp Institute, 2040 Whitfield Ave, Sarasota, FL, 34243, USA
    Neuromolecular Med 13:275-88. 2011
  5. pmc Serum Abeta levels as predictors of conversion to mild cognitive impairment/Alzheimer disease in an ADAPT subcohort
    Laila Abdullah
    Roskamp Institute, Sarasota, Florida 34243, USA
    Mol Med 15:432-7. 2009
  6. ncbi request reprint The influence of diagnosis, intra- and inter-person variability on serum and plasma Abeta levels
    Laila Abdullah
    Roskamp Institute, 2040 Whitfield Avenue, Sarasota, FL 34243, United States
    Neurosci Lett 428:53-8. 2007
  7. pmc High serum Abeta and vascular risk factors in first-degree relatives of Alzheimer's disease patients
    Laila Abdullah
    Roskamp Institute, Sarasota, Florida 34243, USA
    Mol Med 15:95-100. 2009
  8. doi request reprint Diagnostic utility of APOE, soluble CD40, CD40L, and Abeta1-40 levels in plasma in Alzheimer's disease
    Ghania Ait-Ghezala
    Roskamp Institute, 2040 Whitfield Avenue, Sarasota, FL 34243, USA
    Cytokine 44:283-7. 2008
  9. ncbi request reprint Serum beta-amyloid correlates with neuropsychological impairment
    Cheryl A Luis
    Roskamp Institute, Sarasota, FL, USA
    Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 16:203-18. 2009
  10. doi request reprint Anti-inflammatory activity of anatabine via inhibition of STAT3 phosphorylation
    Daniel Paris
    The Roskamp Institute, 2040 Whitfield Avenue, Sarasota, Florida 34243, USA
    Eur J Pharmacol 698:145-53. 2013

Detail Information

Publications17

  1. ncbi request reprint Chronic elevation of phosphocholine containing lipids in mice exposed to Gulf War agents pyridostigmine bromide and permethrin
    Laila Abdullah
    Roskamp Institute, 2040 Whitfield Ave, Sarasota, FL 34243, United States Electronic address
    Neurotoxicol Teratol 40:74-84. 2013
    ..Our studies provide a new direction for GWI research, which will be useful for developing suitable therapies for treating GWI. ..
  2. doi request reprint Lipidomic profiling of phosphocholine-containing brain lipids in mice with sensorimotor deficits and anxiety-like features after exposure to Gulf War agents
    Laila Abdullah
    Roskamp Institute, Sarasota, FL 34243, USA
    Neuromolecular Med 14:349-61. 2012
    ....
  3. ncbi request reprint The cyclooxygenase 2 -765 C promoter allele is a protective factor for Alzheimer's disease
    Laila Abdullah
    Roskamp Institute, 2040 Whitfield Ave Sarasota, FL, USA
    Neurosci Lett 395:240-3. 2006
    ..464, CI = [.351-.885], p = .013). In this sample, the C allele of COX-2 -765 promoter polymorphism is associated with decreased risk of Alzheimer's disease, a finding which further supports the involvement of COX-2 in AD etiology...
  4. doi request reprint Proteomic CNS profile of delayed cognitive impairment in mice exposed to Gulf War agents
    Laila Abdullah
    Roskamp Institute, 2040 Whitfield Ave, Sarasota, FL, 34243, USA
    Neuromolecular Med 13:275-88. 2011
    ..Evaluation of the potential role of these biological functions in GWI will be useful in identifying molecular pathways that can be targeted for the development of novel therapeutics against GWI...
  5. pmc Serum Abeta levels as predictors of conversion to mild cognitive impairment/Alzheimer disease in an ADAPT subcohort
    Laila Abdullah
    Roskamp Institute, Sarasota, Florida 34243, USA
    Mol Med 15:432-7. 2009
    ..In this subcohort of individuals at risk for AD, the association of Abeta with vascular risk factors and medications to treat these conditions did not interfere with Abeta's predictive value for MCI/AD...
  6. ncbi request reprint The influence of diagnosis, intra- and inter-person variability on serum and plasma Abeta levels
    Laila Abdullah
    Roskamp Institute, 2040 Whitfield Avenue, Sarasota, FL 34243, United States
    Neurosci Lett 428:53-8. 2007
    ....
  7. pmc High serum Abeta and vascular risk factors in first-degree relatives of Alzheimer's disease patients
    Laila Abdullah
    Roskamp Institute, Sarasota, Florida 34243, USA
    Mol Med 15:95-100. 2009
    ..Longitudinal evaluation of blood Abeta in this cohort will provide a better understanding of the significance of this association in AD etiology...
  8. doi request reprint Diagnostic utility of APOE, soluble CD40, CD40L, and Abeta1-40 levels in plasma in Alzheimer's disease
    Ghania Ait-Ghezala
    Roskamp Institute, 2040 Whitfield Avenue, Sarasota, FL 34243, USA
    Cytokine 44:283-7. 2008
    ..Thus, we present preliminary evidence for potential usefulness for combination of plasma sCD40, sCD40L along with Abeta(1-40) and APOE epsilon4 in improving the clinical diagnosis of AD...
  9. ncbi request reprint Serum beta-amyloid correlates with neuropsychological impairment
    Cheryl A Luis
    Roskamp Institute, Sarasota, FL, USA
    Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 16:203-18. 2009
    ....
  10. doi request reprint Anti-inflammatory activity of anatabine via inhibition of STAT3 phosphorylation
    Daniel Paris
    The Roskamp Institute, 2040 Whitfield Avenue, Sarasota, Florida 34243, USA
    Eur J Pharmacol 698:145-53. 2013
    ..Overall our data show that the anti-inflammatory activity of anatabine in vitro and in vivo is mediated in part via an inhibition of STAT3 phosphorylation...
  11. pmc Feasibility of Predicting MCI/AD Using Neuropsychological Tests and Serum β-Amyloid
    Cheryl A Luis
    Roskamp Institute, 2040 Whitfield Avenue, Sarasota, FL 34243, USA
    Int J Alzheimers Dis 2011:786264. 2011
    ....
  12. ncbi request reprint CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker of Alzheimer's disease
    Jun Tan
    Department of Psychiatry, Roskamp Institute, University of South Florida, 3515 E Fletcher Ave, Tampa, FL 33613, USA
    J Neuroimmunol 132:164-72. 2002
    ....
  13. ncbi request reprint Exposure to an organophosphate pesticide, individually or in combination with other Gulf War agents, impairs synaptic integrity and neuronal differentiation, and is accompanied by subtle microvascular injury in a mouse model of Gulf War agent exposure
    Joseph O Ojo
    Roskamp Institute, Sarasota, Florida, USA
    Neuropathology 34:109-27. 2014
    ..These data support early (subtle) neurotoxic effects on the brain following exposure to GW agents. ..
  14. ncbi request reprint Inhibition of angiogenesis by Abeta peptides
    Daniel Paris
    The Roskamp Institute, Sarasota, Florida 34243, USA
    Angiogenesis 7:75-85. 2004
    ..Similarly to the intra-tumoral injection regimen, Abeta delivered intraperitoneally also suppressed the growth of human lung adenocarcinoma tumor xenografts. Altogether our data show that Abeta is an angiogenesis inhibitor...
  15. ncbi request reprint Cocaine-induced oxidative stress precedes cell death in human neuronal progenitor cells
    H Fai Poon
    Roskamp Institute, 2040 Whitfield Ave, Sarasota, FL 34243, United States
    Neurochem Int 50:69-73. 2007
    ..This may have implications for the consequences of cocaine abuse in situations where antioxidant capacity is compromised, as in the aging brain...
  16. pmc Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib
    Barbara K Martin
    Arch Neurol 65:896-905. 2008
    ..Observational studies have shown reduced risk of Alzheimer dementia in users of nonsteroidal anti-inflammatory drugs...
  17. ncbi request reprint Beneficial effect of cholinesterase inhibitor medications on recognition memory performance in mild to moderate Alzheimer's disease: preliminary findings
    Timothy A Crowell
    Roskamp Institute Memory Clinic, Tampa, Florida 33617, USA
    J Geriatr Psychiatry Neurol 19:13-5. 2006
    ..The implications of this on clinical care and functional abilities as well as future directions are discussed...