Heinz Steiner

Summary

Affiliation: Rosalind Franklin University of Medicine and Science
Country: USA

Publications

  1. ncbi Addiction-related gene regulation: risks of exposure to cognitive enhancers vs. other psychostimulants
    Heinz Steiner
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, North Chicago, IL 60064, United States
    Prog Neurobiol 100:60-80. 2013
  2. ncbi Fluoxetine potentiates methylphenidate-induced gene regulation in addiction-related brain regions: concerns for use of cognitive enhancers?
    Heinz Steiner
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science, Chicago Medical School, North Chicago, Illinois, USA
    Biol Psychiatry 67:592-4. 2010
  3. ncbi Fluoxetine potentiation of methylphenidate-induced neuropeptide expression in the striatum occurs selectively in direct pathway (striatonigral) neurons
    Vincent Van Waes
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL 60064, USA
    J Neurochem 122:1054-64. 2012
  4. ncbi Repeated methylphenidate treatment in adolescent rats alters gene regulation in the striatum
    Cindy L Brandon
    Department of Cellular and Molecular Pharmacology, Finch University of Health Sciences/The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Eur J Neurosci 18:1584-92. 2003
  5. ncbi Selective serotonin reuptake inhibitor antidepressants potentiate methylphenidate (Ritalin)-induced gene regulation in the adolescent striatum
    Vincent Van Waes
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL 60064, USA
    Eur J Neurosci 32:435-47. 2010
  6. ncbi Long-lasting dysregulation of gene expression in corticostriatal circuits after repeated cocaine treatment in adult rats: effects on zif 268 and homer 1a
    Cagri T Unal
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL 60064, USA
    Eur J Neurosci 29:1615-26. 2009
  7. ncbi Motor-skill learning-associated gene regulation in the striatum: effects of cocaine
    Ingo Willuhn
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science/The Chicago Medical School, North Chicago, IL 60064, USA
    Neuropsychopharmacology 31:2669-82. 2006
  8. ncbi Dysregulation of gene induction in corticostriatal circuits after repeated methylphenidate treatment in adolescent rats: differential effects on zif 268 and homer 1a
    Lindsay Cotterly
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Eur J Neurosci 25:3617-28. 2007
  9. ncbi Skill-memory consolidation in the striatum: critical for late but not early long-term memory and stabilized by cocaine
    Ingo Willuhn
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Behav Brain Res 199:103-7. 2009
  10. ncbi Methylphenidate and cocaine: the same effects on gene regulation?
    Motoyo Yano
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Trends Pharmacol Sci 28:588-96. 2007

Research Grants

  1. Behavior/Drug Interactions in Striatal gene Regulation
    Heinz Steiner; Fiscal Year: 2003
  2. BASAL GANGLIA OUTPUT AND PSYCHOSTIMULANT ABUSE
    Heinz Steiner; Fiscal Year: 2009

Collaborators

Detail Information

Publications17

  1. ncbi Addiction-related gene regulation: risks of exposure to cognitive enhancers vs. other psychostimulants
    Heinz Steiner
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, North Chicago, IL 60064, United States
    Prog Neurobiol 100:60-80. 2013
    ..These neuronal changes may contribute to the addiction liability of the psychostimulant cognitive enhancers...
  2. ncbi Fluoxetine potentiates methylphenidate-induced gene regulation in addiction-related brain regions: concerns for use of cognitive enhancers?
    Heinz Steiner
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science, Chicago Medical School, North Chicago, Illinois, USA
    Biol Psychiatry 67:592-4. 2010
    ....
  3. ncbi Fluoxetine potentiation of methylphenidate-induced neuropeptide expression in the striatum occurs selectively in direct pathway (striatonigral) neurons
    Vincent Van Waes
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL 60064, USA
    J Neurochem 122:1054-64. 2012
    ..These results suggest that SSRIs may enhance the addiction liability of methylphenidate...
  4. ncbi Repeated methylphenidate treatment in adolescent rats alters gene regulation in the striatum
    Cindy L Brandon
    Department of Cellular and Molecular Pharmacology, Finch University of Health Sciences/The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Eur J Neurosci 18:1584-92. 2003
    ..Thus, our findings demonstrate that acute and repeated methylphenidate treatment can produce molecular alterations similar to other psychostimulants...
  5. ncbi Selective serotonin reuptake inhibitor antidepressants potentiate methylphenidate (Ritalin)-induced gene regulation in the adolescent striatum
    Vincent Van Waes
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL 60064, USA
    Eur J Neurosci 32:435-47. 2010
    ..In so far as such gene regulation is implicated in psychostimulant addiction, our findings suggest that SSRIs may enhance the addiction potential of methylphenidate...
  6. ncbi Long-lasting dysregulation of gene expression in corticostriatal circuits after repeated cocaine treatment in adult rats: effects on zif 268 and homer 1a
    Cagri T Unal
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL 60064, USA
    Eur J Neurosci 29:1615-26. 2009
    ..Future studies will have to elucidate the role of such neuronal changes in psychostimulant addiction...
  7. ncbi Motor-skill learning-associated gene regulation in the striatum: effects of cocaine
    Ingo Willuhn
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science/The Chicago Medical School, North Chicago, IL 60064, USA
    Neuropsychopharmacology 31:2669-82. 2006
    ..Such cocaine effects may contribute to aberrant motor learning implicated in psychostimulant addiction...
  8. ncbi Dysregulation of gene induction in corticostriatal circuits after repeated methylphenidate treatment in adolescent rats: differential effects on zif 268 and homer 1a
    Lindsay Cotterly
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Eur J Neurosci 25:3617-28. 2007
    ..This drug-induced dissociation in cortical and striatal functioning was associated with enhanced levels of behavioural stereotypies, suggesting disrupted motor switching function...
  9. ncbi Skill-memory consolidation in the striatum: critical for late but not early long-term memory and stabilized by cocaine
    Ingo Willuhn
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Behav Brain Res 199:103-7. 2009
    ..Furthermore, cocaine appeared to stabilize motor-memory formation by protecting consolidation processes after the training...
  10. ncbi Methylphenidate and cocaine: the same effects on gene regulation?
    Motoyo Yano
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Trends Pharmacol Sci 28:588-96. 2007
    ....
  11. ncbi Topography of methylphenidate (ritalin)-induced gene regulation in the striatum: differential effects on c-fos, substance P and opioid peptides
    Motoyo Yano
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science/The Chicago Medical School, North Chicago, IL 60064, USA
    Neuropsychopharmacology 30:901-15. 2005
    ..These molecular changes are similar, but not identical, to those produced by other psychostimulants...
  12. ncbi Amphetamine increases tyrosine kinase-B receptor expression in the dorsal striatum
    Gloria E Meredith
    Department of Cellular and Molecular Pharmacology, Chicago Medical School Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA
    Neuroreport 17:75-8. 2006
    ..These findings indicate that changes in striatal tyrosine kinase-B signaling could play a role in neuroadaptations and behavioral changes induced by amphetamine treatment...
  13. ncbi CB1 Cannabinoid Receptor Expression in the Striatum: Association with Corticostriatal Circuits and Developmental Regulation
    Vincent Van Waes
    Department of Cellular and Molecular Pharmacology, The Chicago Medical School, Rosalind Franklin University of Medicine and Science North Chicago, IL, USA
    Front Pharmacol 3:21. 2012
    ....
  14. ncbi Differential developmental trajectories for CB1 cannabinoid receptor expression in limbic/associative and sensorimotor cortical areas
    Lijun Heng
    Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, North Chicago, Illinois 60064, USA
    Synapse 65:278-86. 2011
    ..sensorimotor systems. Therefore, cannabis use during adolescence likely differentially affects limbic/associative and sensorimotor cortical circuits...
  15. ncbi Interactions between Procedural Learning and Cocaine Exposure Alter Spontaneous and Cortically Evoked Spike Activity in the Dorsal Striatum
    Janie M Ondracek
    Department of Cellular and Molecular Pharmacology, The Chicago Medical School Rosalind Franklin University of Medicine and Science North Chicago, IL, USA
    Front Neurosci 4:206. 2010
    ..Such changes may contribute to the transition from recreational to habitual or compulsive drug taking behavior...
  16. ncbi Topography of cocaine-induced gene regulation in the rat striatum: relationship to cortical inputs and role of behavioural context
    Ingo Willuhn
    Department of Cellular and Molecular Pharmacology, Finch University of Health Sciences/The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Eur J Neurosci 17:1053-66. 2003
    ....
  17. ncbi Augmented D1 dopamine receptor signaling and immediate-early gene induction in adult striatum after prenatal cocaine
    Thomas F Tropea
    Laboratory of Molecular and Developmental Neuroscience, Department of Pediatrics, Division of Pediatric Neurology, New York Presbyterian Hospital Weill Cornell Medical College, New York, New York 10021, USA
    Biol Psychiatry 63:1066-74. 2008
    ..The present study employed a mouse model to investigate alterations in D(1) dopamine receptor signaling and downstream immediate-early gene induction in the striatum of mice exposed to cocaine in utero...

Research Grants5

  1. Behavior/Drug Interactions in Striatal gene Regulation
    Heinz Steiner; Fiscal Year: 2003
    ..These studies should provide new insights into how the behavior executed during the drug action can influence drug-induced neuroplasticity in the striaturn. ..
  2. BASAL GANGLIA OUTPUT AND PSYCHOSTIMULANT ABUSE
    Heinz Steiner; Fiscal Year: 2009
    ..This work will help establish an improved cellular framework necessary to understand and successfully treat cocaine addiction. ..