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Genomes and Genes | David J RademacherSummaryAffiliation: Rosalind Franklin University of Medicine and Science Country: USA Publications
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The effects of infusions of CART 55-102 into the basolateral amygdala on amphetamine-induced conditioned place preference in ratsDavid J Rademacher
Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science, Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
Psychopharmacology (Berl) 208:499-509. 2010..The formation of context-drug associations produces either conditioned place preference (CPP) or conditioned place aversion (CPA)...
Context modulates the expression of conditioned motor sensitization, cellular activation and synaptophysin immunoreactivityDavid J Rademacher
Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60064, USA
Eur J Neurosci 26:2661-8. 2007..These data indicate that the basolateral amygdala-nucleus accumbens core pathway is necessary for the context-elicited conditioned motor responses, while the hippocampus encodes the spatial context...- Interactions between endocannabinoids and stress-induced decreased sensitivity to natural rewardDavid J Rademacher
Medical College of Wisconsin, Department of Pharmacology and Toxicology, 8701 Watertown Plank Road, Milwaukee, WI 53226 USA
Prog Neuropsychopharmacol Biol Psychiatry 31:633-41. 2007..The findings of the present study indicate that the CB(1)/endocannabinoid signaling system is an important allostatic mediator that both modulates the responses of mice to stress and is itself modulated by stress... 
Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in miceDavid J Rademacher
Medical College of Wisconsin, Department of Pharmacology and Toxicology, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Neuropharmacology 54:108-16. 2008..These studies are consistent with the hypothesis that stress exposure alters endocannabinoid signaling in the brain and that alterations in endocannabinoid signaling occur during habituation to stress...- Inhibition of restraint stress-induced neural and behavioural activation by endogenous cannabinoid signallingSachin Patel
Department of Pharmacology and Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Eur J Neurosci 21:1057-69. 2005.... - Anandamide content and interaction of endocannabinoid/GABA modulatory effects in the NTS on baroreflex-evoked sympathoinhibitionJeanne L Seagard
Zablocki Dept of Veterans Affairs Medical Center, Research Service 151, 5000 W National Ave, Milwaukee, WI 53295, USA
Am J Physiol Heart Circ Physiol 286:H992-1000. 2004.... - The neural substrates of amphetamine conditioned place preference: implications for the formation of conditioned stimulus-reward associationsDavid J Rademacher
Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science, Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
Eur J Neurosci 24:2089-97. 2006..These data therefore suggest that the formation of conditioned stimulus-reward associations requires, at least in part, activation of amygdalar-hippocampal circuits... - The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activitySachin Patel
Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI, USA
J Lipid Res 46:342-9. 2005..These data demonstrate that FAAH activity differentially affects AEA and OEA/PEA contents postmortem and suggest that AEA formation specifically occurs via an ethanolamine-dependent route postmortem... - U-46619 but not serotonin increases endocannabinoid content in middle cerebral artery: evidence for functional relevanceDavid J Rademacher
Medical College of Wisconsin, Dept of Pharmacology and Toxicology, 8701 Watertown Plank Rd, Milwaukee, WI 53226 0509, USA
Am J Physiol Heart Circ Physiol 288:H2694-701. 2005..These results suggest that MCA production of eCBs is not regulated by constriction per se but likely via a signaling pathway that is specific for TXA(2) receptors and not 5-HT receptors... - Amphetamine-associated contextual learning is accompanied by structural and functional plasticity in the basolateral amygdalaDavid J Rademacher
Department of Cellular and Molecular Pharmacology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA
J Neurosci 30:4676-86. 2010..Thus, context-drug associations are accompanied by structural and functional plasticity in the BLA, findings that have important implications for drug-seeking behavior... - Waterborne lead exposure affects brain endocannabinoid content in male but not female fathead minnows (Pimephales promelas)David J Rademacher
Department of Pharmacology and Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Neurotoxicology 26:9-15. 2005..As eCBs serve as activity-dependent retrograde inhibitors of neurotransmitter release, the increase in brain eCB content would accentuate Pb2+-induced decreases in evoked neurotransmitter release in male but not female fathead minnows... - Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axisSachin Patel
Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Endocrinology 145:5431-8. 2004.... - Production of hydroxyeicosatetraenoic acids and prostaglandins by a novel rat microglial cell lineDavid J Rademacher
Department of Pharmacology and Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
J Neuroimmunol 149:130-41. 2004..RTMGL1 synthesize 5-HETE from arachidonic acid (AA) likely via a 5-lipoxygenase (LO). Thus, RTMGL1 have morphological and histological characteristics of primary microglia and metabolize AA via both COX and LO pathways... - The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolaseSachin Patel
Department of Pharmacology and Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Br J Pharmacol 139:1005-13. 2003.... - Differential regulation of the endocannabinoids anandamide and 2-arachidonylglycerol within the limbic forebrain by dopamine receptor activitySachin Patel
Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
J Pharmacol Exp Ther 306:880-8. 2003.... - Microinjection of a cannabinoid receptor antagonist into the NTS increases baroreflex duration in dogsDavid J Rademacher
Department of Pharmacology and Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226-0509, USA
Am J Physiol Heart Circ Physiol 284:H1570-6. 2003..Microinjection of WIN-55212-2 had no effect on the baroreflex. These data suggest that endocannabinoids can modulate the excitability of NTS neurons involved in the baroreceptor reflex, leading to modulation of baroreflex regulation... - Increased synapses in the medial prefrontal cortex are associated with repeated amphetamine administrationMaud M Morshedi
Department of Cellular and Molecular Pharmacology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA
Synapse 63:126-35. 2009..Therefore, behavioral sensitization as a result of repeated exposure to AMPH is accompanied by the increased formation of spine, but not dendritic, synapses onto pyramidal neurons in the mPFC... - Effects of the selective mu(1)-opioid receptor antagonist, naloxonazine, on cocaine-induced conditioned place preference and locomotor behavior in ratsDavid J Rademacher
Department of Psychology, University of Wisconsin Milwaukee, 224 Garland Hall, 2441 East Hartford Avenue, Milwaukee, WI 53211, USA
Neurosci Lett 332:159-62. 2002..These findings indicate that the rewarding effects of cocaine can be blocked solely by mu(1)-opioid receptor antagonism and are consistent with the view that the locomotor and rewarding effects of drugs can be dissociated... - Effects of dietary lead and/or dimercaptosuccinic acid exposure on regional serotonin and serotonin metabolite content in rainbow trout (Oncorhynchus mykiss)David J Rademacher
Department of Psychology, University of Wisconsin Milwaukee, 224 Garland Hall, 2441 East Hartford Avenue, Milwaukee, WI 53211, USA
Neurosci Lett 339:156-60. 2003..DMSA increased 5-HIAA content in all three brain regions and increased 5-HT content only the optic tectum. Treatment with DMSA may be more effective than removal of Pb from the diet in reversing Pb-induced alterations in 5-HT... - Effects of cocaine and putative atypical antipsychotics on rat social behavior: an ethopharmacological studyDavid J Rademacher
Department of Psychology, University of Wisconsin Milwaukee, 224 Garland Hall, 2441 East Hartford Avenue, Milwaukee, WI 53211, USA
Pharmacol Biochem Behav 73:769-78. 2002..Amperozide, clozapine and olanzapine have anticonflict and anxiolytic effects, as well as potent and specific antiaggressive effects... - Acute effects of amperozide and paroxetine on social cohesion in male conspecificsDavid J Rademacher
Department of Psychology, University of Wisconsin Milwaukee, Milwaukee, WI, USA
Brain Res Bull 58:187-91. 2002..Amperozide may prove to be a more effective treatment for social anxiety disorder than paroxetine, which is supported by our results... - Downregulation of endocannabinoid signaling in the hippocampus following chronic unpredictable stressMatthew N Hill
Department of Psychology, University of British Columbia, Vancouver, BC, Canada V6T 1Z4
Neuropsychopharmacology 30:508-15. 2005....