Judith Potashkin

Summary

Affiliation: Rosalind Franklin University of Medicine and Science
Country: USA

Publications

  1. pmc Regulation of retention of FosB intron 4 by PTB
    Victor Marinescu
    Department of Cellular and Molecular Pharmacology, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, United States of America
    PLoS ONE 2:e828. 2007
  2. pmc Integrative network analysis unveils convergent molecular pathways in Parkinson's disease and diabetes
    Jose A Santiago
    The Cellular and Molecular Pharmacology Department, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, United States of America
    PLoS ONE 8:e83940. 2013
  3. pmc The promise of neuroprotective agents in Parkinson's disease
    Stacey E Seidl
    Department of Biological Sciences, DePaul University Chicago, IL, USA
    Front Neurol 2:68. 2011
  4. pmc The Role of miRNAs as Key Regulators in the Neoplastic Microenvironment
    K K Wentz-Hunter
    Biological, Chemical and Physical Sciences Department, College of Arts and Sciences, Roosevelt University, Chicago, IL 60605, USA
    Mol Biol Int 2011:839872. 2011
  5. pmc Limitations of animal models of Parkinson's disease
    J A Potashkin
    Department of Cellular and Molecular Pharmacology, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60064 3037, USA
    Parkinsons Dis 2011:658083. 2010
  6. pmc Biosignatures for Parkinson's disease and atypical parkinsonian disorders patients
    Judith A Potashkin
    The Cellular and Molecular Pharmacology Department, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, North Chicago, Illinois, United States of America
    PLoS ONE 7:e43595. 2012
  7. ncbi request reprint MPTP administration in mice changes the ratio of splice isoforms of fosB and rgs9
    Judith A Potashkin
    Department of Cellular and Molecular Pharmacology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Brain Res 1182:1-10. 2007
  8. pmc Modeling PD pathogenesis in mice: advantages of a chronic MPTP protocol
    Gloria E Meredith
    Department of Cellular and Molecular Pharmacology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Parkinsonism Relat Disord 14:S112-5. 2008
  9. ncbi request reprint The role of oxidative stress in the dysregulation of gene expression and protein metabolism in neurodegenerative disease
    Judith A Potashkin
    Department of Cellular and Molecular Pharmacology, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, USA
    Antioxid Redox Signal 8:144-51. 2006
  10. pmc Regulation of fosB and DeltafosB mRNA expression: in vivo and in vitro studies
    Imran N Alibhai
    Department of Psychiatry and Center for Basic Neuroscience, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Brain Res 1143:22-33. 2007

Research Grants

  1. COCAINE REGULATION OF FOSB SPLICING
    Judith Potashkin; Fiscal Year: 2002
  2. COCAINE REGULATION OF FOSB SPLICING
    Judith Potashkin; Fiscal Year: 2003
  3. COCAINE REGULATION OF FOSB SPLICING
    Judith Potashkin; Fiscal Year: 2004

Collaborators

Detail Information

Publications11

  1. pmc Regulation of retention of FosB intron 4 by PTB
    Victor Marinescu
    Department of Cellular and Molecular Pharmacology, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, United States of America
    PLoS ONE 2:e828. 2007
    ..These results demonstrate for the first time that phosphorylated PTB promotes intron retention and thereby silences the splicing of fosB I4...
  2. pmc Integrative network analysis unveils convergent molecular pathways in Parkinson's disease and diabetes
    Jose A Santiago
    The Cellular and Molecular Pharmacology Department, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, United States of America
    PLoS ONE 8:e83940. 2013
    ..In this study, we used an integrated network approach to investigate the extent to which Parkinson's disease and type 2 diabetes are linked at the molecular level...
  3. pmc The promise of neuroprotective agents in Parkinson's disease
    Stacey E Seidl
    Department of Biological Sciences, DePaul University Chicago, IL, USA
    Front Neurol 2:68. 2011
    ..The identification of neuroprotective agents for PD provides us with therapeutic opportunities for modifying the course of disease progression and, perhaps, reducing the risk of onset when preclinical biomarkers become available...
  4. pmc The Role of miRNAs as Key Regulators in the Neoplastic Microenvironment
    K K Wentz-Hunter
    Biological, Chemical and Physical Sciences Department, College of Arts and Sciences, Roosevelt University, Chicago, IL 60605, USA
    Mol Biol Int 2011:839872. 2011
    ..In this paper, we discuss the influence of miRNAs on the tumor microenvironment as it relates to cancer progression. We conclude that miRNAs are a critical component in understanding invasion and metastasis of cancer cells...
  5. pmc Limitations of animal models of Parkinson's disease
    J A Potashkin
    Department of Cellular and Molecular Pharmacology, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60064 3037, USA
    Parkinsons Dis 2011:658083. 2010
    ..In this paper we will explain the limitations of animal models of PD and why their use is inappropriate for the study of some aspects of PD...
  6. pmc Biosignatures for Parkinson's disease and atypical parkinsonian disorders patients
    Judith A Potashkin
    The Cellular and Molecular Pharmacology Department, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, North Chicago, Illinois, United States of America
    PLoS ONE 7:e43595. 2012
    ..Analysis of the PD biomarkers identified a regulatory network with nodes centered on the transcription factors HNF4A and TNF, which have been implicated in insulin regulation...
  7. ncbi request reprint MPTP administration in mice changes the ratio of splice isoforms of fosB and rgs9
    Judith A Potashkin
    Department of Cellular and Molecular Pharmacology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Brain Res 1182:1-10. 2007
    ..The data indicate that the pattern of splice isoforms of fosB and rgs9 reflects the brain's immediate and long-term responses to the physiological stress associated with Parkinsonism...
  8. pmc Modeling PD pathogenesis in mice: advantages of a chronic MPTP protocol
    Gloria E Meredith
    Department of Cellular and Molecular Pharmacology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Parkinsonism Relat Disord 14:S112-5. 2008
    ..These data support the validity of the MPTP/p model for unravelling the degenerative processes in PD and testing therapies that slow their progress...
  9. ncbi request reprint The role of oxidative stress in the dysregulation of gene expression and protein metabolism in neurodegenerative disease
    Judith A Potashkin
    Department of Cellular and Molecular Pharmacology, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, USA
    Antioxid Redox Signal 8:144-51. 2006
    ....
  10. pmc Regulation of fosB and DeltafosB mRNA expression: in vivo and in vitro studies
    Imran N Alibhai
    Department of Psychiatry and Center for Basic Neuroscience, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9070, USA
    Brain Res 1143:22-33. 2007
    ....

Research Grants3

  1. COCAINE REGULATION OF FOSB SPLICING
    Judith Potashkin; Fiscal Year: 2002
    ..Because dFosB is also induced by chronic administration of other drugs of abuse, such as amphetamine, nicotine and opiates, the results obtained in this study may also lead to a better understanding of drug addiction. ..
  2. COCAINE REGULATION OF FOSB SPLICING
    Judith Potashkin; Fiscal Year: 2003
    ..Because dFosB is also induced by chronic administration of other drugs of abuse, such as amphetamine, nicotine and opiates, the results obtained in this study may also lead to a better understanding of drug addiction. ..
  3. COCAINE REGULATION OF FOSB SPLICING
    Judith Potashkin; Fiscal Year: 2004
    ..Because dFosB is also induced by chronic administration of other drugs of abuse, such as amphetamine, nicotine and opiates, the results obtained in this study may also lead to a better understanding of drug addiction. ..