Joanne Kwak-Kim

Summary

Affiliation: Rosalind Franklin University of Medicine and Science
Country: USA

Publications

  1. ncbi request reprint T helper 1 and 2 immune responses in relationship to pregnancy, nonpregnancy, recurrent spontaneous abortions and infertility of repeated implantation failures
    Joanne Y H Kwak-Kim
    Department of Obstetrics and Gynecology, Rosalind Franklin University of Medicine and Science, Chicago Medical School, North Chicago, IL 60064, USA
    Chem Immunol Allergy 88:64-79. 2005
  2. doi request reprint Recurrent pregnancy loss: a disease of inflammation and coagulation
    Joanne Kwak-Kim
    Departments of Obstetrics and Gynecology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL, USA
    J Obstet Gynaecol Res 35:609-22. 2009
  3. doi request reprint Clinical implication of natural killer cells and reproduction
    Joanne Kwak-Kim
    Department of Obstetrics and Gynecology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL 60064, USA
    Am J Reprod Immunol 59:388-400. 2008
  4. ncbi request reprint Elevated Th1/Th2 cell ratios in a pregnant woman with a history of RSA, secondary Sjögren's syndrome and rheumatoid arthritis complicated with one fetal demise of twin pregnancy
    Joanne Kwak-Kim
    Reproductive Medicine, Department of Obstetrics and Gynecology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL 60064, USA
    Am J Reprod Immunol 58:325-9. 2007
  5. ncbi request reprint Expression of natural cytotoxicity receptors and a2V-ATPase on peripheral blood NK cell subsets in women with recurrent spontaneous abortions and implantation failures
    Atsushi Fukui
    Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL 60064, USA
    Am J Reprod Immunol 56:312-20. 2006
  6. ncbi request reprint Intracellular cytokine expression of peripheral blood natural killer cell subsets in women with recurrent spontaneous abortions and implantation failures
    Atsushi Fukui
    Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, Illinois 60064, USA
    Fertil Steril 89:157-65. 2008
  7. ncbi request reprint An in vitro coculture model to study cytokine profiles of natural killer cells during maternal immune cell-trophoblast interactions
    Evangelos Ntrivalas
    Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, Chicago, Illinois 60064, USA
    J Soc Gynecol Investig 13:196-202. 2006
  8. doi request reprint Women with multiple implantation failures and recurrent pregnancy losses have increased peripheral blood T cell activation
    Kwang Moon Yang
    Department of Obstetrics and Gynecology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60061, USA
    Am J Reprod Immunol 63:370-8. 2010
  9. ncbi request reprint Expression of killer immunoglobulin-like receptors on peripheral blood NK cell subsets of women with recurrent spontaneous abortions or implantation failures
    Evangelos I Ntrivalas
    Department of Clinical Immunology, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Am J Reprod Immunol 53:215-21. 2005
  10. ncbi request reprint The N-terminus domain of the a2 isoform of vacuolar ATPase can regulate interleukin-1beta production from mononuclear cells in co-culture with JEG-3 choriocarcinoma cells
    Evangelos Ntrivalas
    Clinical Immunology Laboratory, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, N Chicago, IL 60064, USA
    Am J Reprod Immunol 57:201-9. 2007

Collaborators

  • Joon Cheol Park
  • Atsushi Fukui
  • Zeev Shoham
  • Gerard Chaouat
  • Alice Gilman-Sachs
  • Evangelos Ntrivalas
  • Kenneth D Beaman
  • Kenneth Beaman
  • Mukesh K Jaiswal
  • Hyunkyong Ahn
  • Na Young Kim
  • Kwang Moon Yang
  • Kuniaki Ota
  • Timothy M Mallers
  • Ae Ra Han
  • Hye Jin Cho
  • Yoon Kyong Choi
  • Evangelos I Ntrivalas
  • Siu Chui Ng
  • Rajasinjham Jeyendran
  • Sivakumar Ramu
  • Mukesh Kumar Jaiswal
  • Peter Vu
  • Benjamin Larsen
  • Hyun Kyong Ahn
  • Heun Yun Kim
  • Simon Thornton
  • Richard Derks
  • Rita Levine
  • Harilaos Mantouvalos
  • Chad R Bowser
  • Poonam Thaker
  • Alan E Beer

Detail Information

Publications22

  1. ncbi request reprint T helper 1 and 2 immune responses in relationship to pregnancy, nonpregnancy, recurrent spontaneous abortions and infertility of repeated implantation failures
    Joanne Y H Kwak-Kim
    Department of Obstetrics and Gynecology, Rosalind Franklin University of Medicine and Science, Chicago Medical School, North Chicago, IL 60064, USA
    Chem Immunol Allergy 88:64-79. 2005
    ..The purpose of this review is to give an overview of what is known about the immune response in women with reproductive failures and provide an update of some of the most recent findings in this field...
  2. doi request reprint Recurrent pregnancy loss: a disease of inflammation and coagulation
    Joanne Kwak-Kim
    Departments of Obstetrics and Gynecology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL, USA
    J Obstet Gynaecol Res 35:609-22. 2009
    ..In addition, metabolic diseases and hematological conditions which often lead to thrombotic/inflammatory conditions are discussed in association with RPL. Finally, current therapeutic options for RPL are reviewed...
  3. doi request reprint Clinical implication of natural killer cells and reproduction
    Joanne Kwak-Kim
    Department of Obstetrics and Gynecology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL 60064, USA
    Am J Reprod Immunol 59:388-400. 2008
    ..Possible neurological and hormonal control of NK cells and NK cell interaction with various leukocyte populations need further investigation in women with reproductive failures...
  4. ncbi request reprint Elevated Th1/Th2 cell ratios in a pregnant woman with a history of RSA, secondary Sjögren's syndrome and rheumatoid arthritis complicated with one fetal demise of twin pregnancy
    Joanne Kwak-Kim
    Reproductive Medicine, Department of Obstetrics and Gynecology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL 60064, USA
    Am J Reprod Immunol 58:325-9. 2007
    ..We report, significantly elevated Th1/Th2 cell ratios were noticed in a pregnant woman with twin pregnancies complicated with one fetal demise, who had a history of RSA, secondary Sjögren's syndrome (SS), and rheumatoid arthritis...
  5. ncbi request reprint Expression of natural cytotoxicity receptors and a2V-ATPase on peripheral blood NK cell subsets in women with recurrent spontaneous abortions and implantation failures
    Atsushi Fukui
    Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, IL 60064, USA
    Am J Reprod Immunol 56:312-20. 2006
    ..In this study, we aim to investigate the expression of NCRs and a2V-ATPase in peripheral blood NK cells of women with recurrent spontaneous abortions (RSA) or implantation failures...
  6. ncbi request reprint Intracellular cytokine expression of peripheral blood natural killer cell subsets in women with recurrent spontaneous abortions and implantation failures
    Atsushi Fukui
    Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, North Chicago, Illinois 60064, USA
    Fertil Steril 89:157-65. 2008
    ..To investigate the cytokine expression by peripheral blood natural killer (NK) cells of women with recurrent spontaneous abortion (SAB) or implantation failures...
  7. ncbi request reprint An in vitro coculture model to study cytokine profiles of natural killer cells during maternal immune cell-trophoblast interactions
    Evangelos Ntrivalas
    Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, Chicago, Illinois 60064, USA
    J Soc Gynecol Investig 13:196-202. 2006
    ..The aim of the present study is to investigate cytokine expression in NK cells when they are in close contact with JEG-3 trophoblast-like cells using an in vitro coculture model...
  8. doi request reprint Women with multiple implantation failures and recurrent pregnancy losses have increased peripheral blood T cell activation
    Kwang Moon Yang
    Department of Obstetrics and Gynecology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60061, USA
    Am J Reprod Immunol 63:370-8. 2010
    ..We aim to determine whether peripheral blood T cell activation is associated with repeated implantation failures or recurrent pregnancy losses (RPLs)...
  9. ncbi request reprint Expression of killer immunoglobulin-like receptors on peripheral blood NK cell subsets of women with recurrent spontaneous abortions or implantation failures
    Evangelos I Ntrivalas
    Department of Clinical Immunology, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Am J Reprod Immunol 53:215-21. 2005
    ..In this study, we investigated the expression of inhibitory and activating receptors in peripheral blood NK cells of women with recurrent spontaneous abortion (RSA) or implantation failures...
  10. ncbi request reprint The N-terminus domain of the a2 isoform of vacuolar ATPase can regulate interleukin-1beta production from mononuclear cells in co-culture with JEG-3 choriocarcinoma cells
    Evangelos Ntrivalas
    Clinical Immunology Laboratory, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, N Chicago, IL 60064, USA
    Am J Reprod Immunol 57:201-9. 2007
    ..Previous studies showed that a2NTD-regulated cytokine production from stimulated T cells. The aim of this study was to determine if a2NTD can regulate cytokine production from immune cells that were in contact with JEG-3 cells...
  11. doi request reprint Immunological modes of pregnancy loss
    Joanne Kwak-Kim
    Reproductive Medicine Program, Department of Obstetrics and Gynecology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, Vernon Hills, IL, USA
    Am J Reprod Immunol 63:611-23. 2010
    ..Potential application of anti-inflammatory therapeutic agents for the prevention of pregnancy losses should be explored further...
  12. doi request reprint V-ATPase upregulation during early pregnancy: a possible link to establishment of an inflammatory response during preimplantation period of pregnancy
    Mukesh K Jaiswal
    Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA
    Reproduction 143:713-25. 2012
    ....
  13. doi request reprint Thyroid autoimmunity and its association with cellular and humoral immunity in women with reproductive failures
    Na Young Kim
    Department of Obstetrics and Gynecology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science North Chicago, IL, USA
    Am J Reprod Immunol 65:78-87. 2011
    ..We aim at investigating the prevalence of TAI in women with recurrent spontaneous abortions (RSA) or unexplained infertility (UI) and its relationship with cellular and humoral immune abnormalities...
  14. doi request reprint Immunologic characteristics of preeclampsia, a comprehensive review
    Hyunkyong Ahn
    Reproductive Medicine, Department of Obstetrics and Gynecology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60061, USA
    Am J Reprod Immunol 65:377-94. 2011
    ..In this review, the immunologic pathogenesis of the PE is reviewed in context of innate and adaptive immunity (both cellular, i.e., T and NK cells, and humoral immunity) in relation to thrombophilic conditions...
  15. doi request reprint Current trends of reproductive immunology practices in in vitro fertilization (IVF) - a first world survey using IVF-Worldwide.com
    Joanne Kwak-Kim
    Department of Obstetrics and Gynecology, Reproductive Medicine, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, Vernon Hills, IL 60061, USA
    Am J Reprod Immunol 69:12-20. 2013
    ....
  16. doi request reprint Obstetrical outcome of anti-inflammatory and anticoagulation therapy in women with recurrent pregnancy loss or unexplained infertility
    Ae Ra Han
    Reproductive Medicine Program, Department of Obstetrics and Gynecology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, Vernon Hills, IL, USA
    Am J Reprod Immunol 68:418-27. 2012
    ..We aimed to investigate the incidence of PE and other obstetrical complications in women with RPL or UI who were treated with anti-inflammatory and anticoagulant treatment...
  17. ncbi request reprint Expression of intracellular Th1 and Th2 cytokines in women with recurrent spontaneous abortion, implantation failures after IVF/ET or normal pregnancy
    Siu Chui Ng
    Department of Microbiology and Immunology, Finch University of Health Sciences The Chicago Medical School, IL 60064, USA
    Am J Reprod Immunol 48:77-86. 2002
    ....
  18. ncbi request reprint Novel role for the N-terminus domain of the a2 isoform of vacuolar ATPase in interleukin-1beta production
    Evangelos Ntrivalas
    Clinical Immunology Laboratory, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA
    Hum Immunol 68:469-77. 2007
    ..These results indicate a regulatory role for a2NTD in IL-1 cytokine production and suggest a unique role for this molecule in inflammation...
  19. pmc Expression of a2 Vacuolar ATPase in Spermatozoa is Associated with Semen Quality and Chemokine-Cytokine Profiles in Infertile Men
    Kuniaki Ota
    Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, United States of America Department of Obstetrics and Gynecology, Rosalind Franklin University of Medicine and Science, Vernon Hills, Illinois, United States of America
    PLoS ONE 8:e70470. 2013
    ..We investigated whether Atp6v0a2 (a2 isoform of vacuolar ATPase) is associated with abnormal semen quality and changes in chemokine-cytokine profiles in infertile men...
  20. doi request reprint Management of women with recurrent pregnancy losses and antiphospholipid antibody syndrome
    Joanne Kwak-Kim
    Reproductive Medicine, Department of Obstetrics and Gynecology, The Chicago Medical School at Rosalind Franklin University of Medicine and Science, Vernon Hills, IL 60061, USA
    Am J Reprod Immunol 69:596-607. 2013
    ..The complex effects of heparin may explain the limited efficacy of heparin treatment in RPL. New diagnostic criteria for obstetrical APS are needed urgently, and new therapeutic approaches should be explored further...
  21. doi request reprint Immune etiology of recurrent pregnancy loss and its diagnosis
    Kenneth D Beaman
    Clinical Immunology Laboratory, Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA
    Am J Reprod Immunol 67:319-25. 2012
    ..It is not imprudent, however, to say that incorporation of laboratory data is essential when diagnosing RSA/RSAI...
  22. doi request reprint Cytokine gene polymorphisms in recurrent spontaneous abortions: a comprehensive review
    Yoon Kyong Choi
    Reproductive Medicine, Department of Obstetrics and Gynecology, Rosalind Franklin University of Medicine and Science The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA
    Am J Reprod Immunol 60:91-110. 2008
    ..Cytokine gene polymorphism studies in women with recurrent spontaneous abortion (RSA) are reviewed to provide comprehensive understanding and a direction for the future investigation...