A R Falsey

Summary

Affiliation: Rochester General Hospital
Country: USA

Publications

  1. ncbi request reprint Detection of respiratory syncytial virus and human metapneumovirus by reverse transcription polymerase chain reaction in adults with and without respiratory illness
    Ann R Falsey
    Department of Medicine, Infectious Diseases Unit, Rochester General Hospital, 1425 Portland Avenue, Rochester, NY 14621, USA
    J Clin Virol 35:46-50. 2006
  2. ncbi request reprint Response of C-reactive protein and serum amyloid A to influenza A infection in older adults
    A R Falsey
    Department of Medicine, Rochester General Hospital, and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14621, USA
    J Infect Dis 183:995-9. 2001
  3. ncbi request reprint Novel coronavirus and severe acute respiratory syndrome
    Ann R Falsey
    Rochester General Hospital, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Lancet 361:1312-3. 2003
  4. ncbi request reprint Impact of rapid diagnosis on management of adults hospitalized with influenza
    Ann R Falsey
    Departments of Medicine, Rochester General Hospital and University of Rochester School of Medicine and Dentistry, Rochester, NY 14621, USA
    Arch Intern Med 167:354-60. 2007
  5. doi request reprint Comparison of the safety and immunogenicity of 2 respiratory syncytial virus (rsv) vaccines--nonadjuvanted vaccine or vaccine adjuvanted with alum--given concomitantly with influenza vaccine to high-risk elderly individuals
    Ann R Falsey
    Department of Medicine, Rochester General Hospital, and University of Rochester School of Medicine, Rochester, NY 14621, USA
    J Infect Dis 198:1317-26. 2008
  6. pmc Comparison of quantitative reverse transcription-PCR to viral culture for assessment of respiratory syncytial virus shedding
    Ann R Falsey
    Department of Medicine Infectious Disease Unit, Rochester General Hospital, University of Rochester School of Medicine and Dentistry, Rochester, New York 14621, USA
    J Clin Microbiol 41:4160-5. 2003
  7. doi request reprint Human metapneumovirus infection in adults
    Ann R Falsey
    Department of Medicine, University of Rochester School of Medicine and Dentistry, and the Department of Medicine, Rochester General Hospital, Rochester, NY 14621, USA
    Pediatr Infect Dis J 27:S80-3. 2008
  8. pmc Detection of respiratory syncytial virus in adults with chronic obstructive pulmonary disease
    Ann R Falsey
    Infectious Diseases Unit, Department of Medicine, Rochester General Hospital, 1425 Portland Avenue, Rochester, NY 14621, USA
    Am J Respir Crit Care Med 173:639-43. 2006
  9. pmc Long-term care facilities: a cornucopia of viral pathogens
    Ann R Falsey
    Department of Medicine, Rochester General Hospital, Rochester, New York 14621, USA
    J Am Geriatr Soc 56:1281-5. 2008
  10. ncbi request reprint Respiratory syncytial virus infection in elderly and high-risk adults
    Ann R Falsey
    Department of Medicine, Rochester General Hospital, Rochester, NY 14621, USA
    N Engl J Med 352:1749-59. 2005

Research Grants

Detail Information

Publications58

  1. ncbi request reprint Detection of respiratory syncytial virus and human metapneumovirus by reverse transcription polymerase chain reaction in adults with and without respiratory illness
    Ann R Falsey
    Department of Medicine, Infectious Diseases Unit, Rochester General Hospital, 1425 Portland Avenue, Rochester, NY 14621, USA
    J Clin Virol 35:46-50. 2006
    ..Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are two viruses for which RT-PCR is now frequently used for diagnosis in adult disease...
  2. ncbi request reprint Response of C-reactive protein and serum amyloid A to influenza A infection in older adults
    A R Falsey
    Department of Medicine, Rochester General Hospital, and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14621, USA
    J Infect Dis 183:995-9. 2001
    ..It is possible that direct effects of CRP may exacerbate preexisting atherosclerotic lesions and may help explain cardiovascular events associated with acute influenza...
  3. ncbi request reprint Novel coronavirus and severe acute respiratory syndrome
    Ann R Falsey
    Rochester General Hospital, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Lancet 361:1312-3. 2003
  4. ncbi request reprint Impact of rapid diagnosis on management of adults hospitalized with influenza
    Ann R Falsey
    Departments of Medicine, Rochester General Hospital and University of Rochester School of Medicine and Dentistry, Rochester, NY 14621, USA
    Arch Intern Med 167:354-60. 2007
    ..We compared the clinical management of patients with influenza whose rapid antigen test result was positive (Ag+) with the management of those whose rapid antigen test result was negative or the test was not performed (Ag0)...
  5. doi request reprint Comparison of the safety and immunogenicity of 2 respiratory syncytial virus (rsv) vaccines--nonadjuvanted vaccine or vaccine adjuvanted with alum--given concomitantly with influenza vaccine to high-risk elderly individuals
    Ann R Falsey
    Department of Medicine, Rochester General Hospital, and University of Rochester School of Medicine, Rochester, NY 14621, USA
    J Infect Dis 198:1317-26. 2008
    ..Respiratory syncytial virus (RSV) has been recognized recently as an important adult pathogen...
  6. pmc Comparison of quantitative reverse transcription-PCR to viral culture for assessment of respiratory syncytial virus shedding
    Ann R Falsey
    Department of Medicine Infectious Disease Unit, Rochester General Hospital, University of Rochester School of Medicine and Dentistry, Rochester, New York 14621, USA
    J Clin Microbiol 41:4160-5. 2003
    ..Quantitative RT-PCR has an excellent correlation with viral titers, as measured by culture, and should be a useful tool for future studies addressing viral load and disease pathogenesis...
  7. doi request reprint Human metapneumovirus infection in adults
    Ann R Falsey
    Department of Medicine, University of Rochester School of Medicine and Dentistry, and the Department of Medicine, Rochester General Hospital, Rochester, NY 14621, USA
    Pediatr Infect Dis J 27:S80-3. 2008
    ..Although the true spectrum of adult hMPV remains to be defined, it is clear that hMPV can result in severe illness the frail elderly and adults with underlying diseases...
  8. pmc Detection of respiratory syncytial virus in adults with chronic obstructive pulmonary disease
    Ann R Falsey
    Infectious Diseases Unit, Department of Medicine, Rochester General Hospital, 1425 Portland Avenue, Rochester, NY 14621, USA
    Am J Respir Crit Care Med 173:639-43. 2006
    ..These data raise the possibility of persistent low-grade infection in this population, which could have implications in COPD pathogenesis...
  9. pmc Long-term care facilities: a cornucopia of viral pathogens
    Ann R Falsey
    Department of Medicine, Rochester General Hospital, Rochester, New York 14621, USA
    J Am Geriatr Soc 56:1281-5. 2008
    ..To determine the frequency and types of respiratory viruses circulating in Boston long-term care facilities (LTCFs) during a 3-year period...
  10. ncbi request reprint Respiratory syncytial virus infection in elderly and high-risk adults
    Ann R Falsey
    Department of Medicine, Rochester General Hospital, Rochester, NY 14621, USA
    N Engl J Med 352:1749-59. 2005
    ..Data on the epidemiology and clinical effects in community-dwelling elderly persons and high-risk adults can help in assessing the need for vaccine development...
  11. ncbi request reprint Respiratory syncytial virus infection in elderly adults
    Ann R Falsey
    Department of Medicine, University of Rochester School of Medicine and Dentistry, and Rochester General Hospital, Rochester, New York, USA
    Drugs Aging 22:577-87. 2005
    ..An effective RSV vaccine has not yet been developed. Therefore, prevention of RSV is limited to standard infection control practices, such as hand washing and the use of gowns and gloves...
  12. ncbi request reprint Community-acquired viral pneumonia
    Ann R Falsey
    Division of Infectious Diseases, Department of Medicine at Rochester General Hospital, 1425 Portland Avenue, Rochester, NY 14621, USA
    Clin Geriatr Med 23:535-52, vi. 2007
    ..Antiviral therapy is available for influenza A and B; specific viral diagnosis, particularly with the use of rapid antigen detection, may be useful for clinical management. Treatment for other viruses primarily is supportive...
  13. ncbi request reprint Respiratory syncytial virus infection in adults
    Ann R Falsey
    Department of Medicine, Infectious Diseases Unit, Rochester General Hospital, Rochester, New York 14621, USA
    Semin Respir Crit Care Med 28:171-81. 2007
    ..Infection control measures are critical to limit spread of RSV. Currently, RSV vaccines are not available, but candidate vaccines are being developed...
  14. ncbi request reprint Viral pneumonia in older adults
    Ann R Falsey
    Department of Medicine, Rochester General Hospital, Rochester, NY 14621, USA
    Clin Infect Dis 42:518-24. 2006
    ..Because clinical features and periods of activity for many viruses overlap, laboratory confirmation of influenza is recommended for cases involving seriously ill or institutionalized patients...
  15. ncbi request reprint Serum antibody decay in adults following natural respiratory syncytial virus infection
    Ann R Falsey
    Department of Medicine at Rochester General Hospital, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14621, USA
    J Med Virol 78:1493-7. 2006
    ..In contrast, titers of uninfected subjects were relatively stable. The partial immunity resulting from a boost in serum antibody following natural RSV infection in adults appears to be short lived...
  16. ncbi request reprint Human metapneumovirus infections in young and elderly adults
    Ann R Falsey
    Infectious Diseases Unit, Rochester General Hospital, University of Rochester School of Medicine and Dentistry, 1425 Portland Avenue, Rochester, NY 14621, USA
    J Infect Dis 187:785-90. 2003
    ..In conclusion, hMPV infection occurs in adults of all ages and may account for a significant portion of persons hospitalized with respiratory infections during some years...
  17. pmc Respiratory syncytial virus infection in adults
    A R Falsey
    Rochester General Hospital and University of Rochester School of Medicine and Dentistry, Rochester, New York 14621, USA
    Clin Microbiol Rev 13:371-84. 2000
    ..An effective RSV vaccine has not yet been developed, and thus prevention of RSV infection is limited to standard infection control practices such as hand washing and the use of gowns and gloves...
  18. doi request reprint Randomized, double-blind controlled phase 3 trial comparing the immunogenicity of high-dose and standard-dose influenza vaccine in adults 65 years of age and older
    Ann R Falsey
    Department of Medicine, Rochester General Hospital, Rochester, NY, USA
    J Infect Dis 200:172-80. 2009
    ..To improve the immunogenicity of influenza vaccine, a high-dose (HD) trivalent, inactivated influenza vaccine was developed...
  19. ncbi request reprint Rhinovirus and coronavirus infection-associated hospitalizations among older adults
    Ann R Falsey
    Division of Infectious Diseases and Department of Medicine, University of Rochester School of Medicine and Dentistry, and Rochester General Hospital, Rochester, New York 14621, USA
    J Infect Dis 185:1338-41. 2002
    ..These data suggest that rhinoviruses and coronaviruses may be associated with serious respiratory illnesses in frail older adults...
  20. pmc Diagnosis of respiratory syncytial virus infection: comparison of reverse transcription-PCR to viral culture and serology in adults with respiratory illness
    Ann R Falsey
    Department of Medicine, Rochester General Hospital, University of Rochester School of Medicine and Dentistry, Rochester, New York 14621, USA
    J Clin Microbiol 40:817-20. 2002
    ..The overall RT-PCR sensitivity was 73%, and specificity was 99%. These data indicate that RT-PCR is an excellent method for the diagnosis of acute RSV infection in adults...
  21. ncbi request reprint Comparison of respiratory syncytial virus humoral immunity and response to infection in young and elderly adults
    A R Falsey
    Department of Medicine, Rochester General Hospital, Rochester, New York 14621, USA
    J Med Virol 59:221-6. 1999
    ..These data suggest that the severe clinical manifestations of RSV in the elderly are not due to a significant defect in humoral immunity...
  22. ncbi request reprint Prothrombotic changes in hemostatic parameters and C-reactive protein in the elderly with winter acute respiratory tract infections
    J T Horan
    Department of Medicine, University of Rochester School of Medicine and Dentistry, NY, USA
    Thromb Haemost 85:245-9. 2001
    ..The associated increase in fibrinogen, an independent risk factor for ischemic heart disease, may be partly responsible for the excess winter vascular mortality...
  23. ncbi request reprint Relationship of serum antibody to risk of respiratory syncytial virus infection in elderly adults
    A R Falsey
    Department of Medicine, University of Rochester School of Medicine and Dentistry and Rochester General Hospital, New York 14621, USA
    J Infect Dis 177:463-6. 1998
    ..1 +/- 2.1, vs. 10.3 +/- 1.5, P = .01). These results suggest that older adults with low titers of serum neutralizing antibody may be at greater risk of developing symptomatic RSV infection than those who have high antibody titers...
  24. ncbi request reprint A simple and reproducible method for collecting nasal secretions in frail elderly adults, for measurement of virus-specific IgA
    E E Walsh
    Division of Infectious Diseases, University of Rochester School of Medicine and Dentistry, Rochester General Hospital, Rochester, NY 14621, USA
    J Infect Dis 179:1268-73. 1999
    ....
  25. ncbi request reprint Reverse transcription polymerase chain reaction (RT-PCR) for diagnosis of respiratory syncytial virus infection in adults: use of a single-tube "hanging droplet" nested PCR
    E E Walsh
    Department of Medicine, Rochester General Hospital, University of Rochester School of Medicine and Dentistry, Rochester, New York 14621, USA
    J Med Virol 63:259-63. 2001
    ..Use of a nested RT-PCR significantly improves the ability to detect RSV in respiratory samples and should improve the ability to rapidly diagnose RSV infection in adults, especially in the elderly...
  26. ncbi request reprint Monoclonal antibody neutralization escape mutants of respiratory syncytial virus with unique alterations in the attachment (G) protein
    E E Walsh
    University of Rochester School of Medicine and Dentistry and Rochester General Hospital, New York 14621, USA
    J Gen Virol 79:479-87. 1998
    ..The predominant form of G produced by RSV-3 was found in infected cell supernatants, consistent with the size of secreted G...
  27. pmc Risk factors for respiratory failure associated with respiratory syncytial virus infection in adults
    Coley B Duncan
    Department of Medicine, Rochester General Hospital, Rochester, New York 14621 3001, USA
    J Infect Dis 200:1242-6. 2009
    ..7 +/- 1.7 plaque-forming units (PFUs)/mL vs 2.4 +/- 1.1 PFUs/mL, P = .02), and high viral load was independently associated with respiratory failure...
  28. pmc Humoral immunity to human metapneumovirus infection in adults
    Ann R Falsey
    Department of Medicine, University of Rochester School of Medicine and Dentistry, United States
    Vaccine 28:1477-80. 2010
    ..Serum antibody may play a role in protection from hMPV infection supporting the development of an hMPV vaccine that stimulates humoral immunity...
  29. ncbi request reprint Protein S declines during winter respiratory infections
    N K Kaba
    University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Thromb Haemost 1:729-34. 2003
    ....
  30. ncbi request reprint Respiratory syncytial virus infection in adults
    Yoshihiko Murata
    Infectious Diseases Unit, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester General Hospital, New York, USA
    Antivir Ther 12:659-70. 2007
    ..Vaccines against RSV remain an unachieved goal. Promising new agents that inhibit the virus-cell fusion, cell-cell fusion, or viral gene expression are currently in development...
  31. ncbi request reprint Is clinical recognition of respiratory syncytial virus infection in hospitalized elderly and high-risk adults possible?
    Edward E Walsh
    Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14621, USA
    J Infect Dis 195:1046-51. 2007
    ..The clinical and radiographic features of respiratory syncytial virus (RSV) infection in elderly hospitalized persons have not been described in detail, to our knowledge, despite its relative frequent occurrence...
  32. pmc Humoral response to the central unglycosylated region of the respiratory syncytial virus attachment protein
    Yoshihiko Murata
    Division of Infectious Diseases, Department of Medicine, University of Rochester School of Medicine and Dentistry and Infectious Diseases Unit, Rochester General Hospital, 601 Elmwood Avenue Box 689, Rochester, NY 14642, USA Yoshihiko
    Vaccine 28:6242-6. 2010
    ..Our results have implications for RSV G-based serological diagnostics and vaccine development...
  33. pmc Circulating antibody-secreting cells during acute respiratory syncytial virus infection in adults
    F Eun Hyung Lee
    Division of Pulmonary and Critical Care Medicine, University of Rochester and Rochester General Hospital, Rochester, New York, USA
    J Infect Dis 202:1659-66. 2010
    ..The specificity and duration of circulating human antibody-secreting cells (ASCs) after vaccination have been well described, but characteristics of ASCs during acute respiratory infections have not been well studied...
  34. ncbi request reprint Pulmonary complications of interpandemic influenza A in hospitalized adults
    Yoshihiko Murata
    Department of Medicine, University of Rochester School of Medicine and Dentistry and Infectious Diseases Unit, Department of Medicine, Rochester General Hospital, Rochester, NY 14621, USA
    J Infect Dis 195:1029-37. 2007
    ....
  35. pmc Human metapneumovirus infections in adults: another piece of the puzzle
    Edward E Walsh
    Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Arch Intern Med 168:2489-96. 2008
    ..We describe the incidence and clinical impact of human metapneumovirus (HMPV), a newly identified virus, in adults...
  36. ncbi request reprint Antivirals for influenza: what is their role in the older patient?
    Ghinwa Dumyati
    Rochester General Hospital, University of Rochester School of Medicine and Dentistry, Rochester, New York 14261, USA
    Drugs Aging 19:777-86. 2002
    ..However, they are costly. Early identification and diagnosis of influenza illnesses are crucial since treatment with antiviral agents should be started within 48 hours of the beginning of illness...
  37. ncbi request reprint Clinical features of influenza A virus infection in older hospitalized persons
    Edward E Walsh
    Division of Infectious Diseases and Department of Medicine, and Department of Biostatistics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14621, USA
    J Am Geriatr Soc 50:1498-503. 2002
    ..To determine the value of clinical parameters in predicting influenza in older persons and those with underlying cardiopulmonary conditions hospitalized with respiratory illnesses...
  38. ncbi request reprint Lack of sensitivity of rapid antigen tests for the diagnosis of respiratory syncytial virus infection in adults
    Aida E Casiano-Colón
    ViaHealth Clinical Laboratories and Pathology, Rochester, NY, USA
    J Clin Virol 28:169-74. 2003
    ..DFA detected 14 (23%), VIDAS detected 12 (20%) and BD detected only 6 (10%) of the RSV infected persons. Rapid antigen detection tests for the diagnosis of RSV respiratory illness in adults are of limited value...
  39. ncbi request reprint Risk factors for severe respiratory syncytial virus infection in elderly persons
    Edward E Walsh
    Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    J Infect Dis 189:233-8. 2004
    ..These data suggest that the induction of neutralizing serum antibody with an RSV vaccine may potentially reduce disease severity in adult populations...
  40. ncbi request reprint Age related differences in humoral immune response to respiratory syncytial virus infection in adults
    Edward E Walsh
    Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    J Med Virol 73:295-9. 2004
    ..The relationship of immune response to disease pathogenesis in older persons deserves further study...
  41. ncbi request reprint Humoral and mucosal immunity in protection from natural respiratory syncytial virus infection in adults
    Edward E Walsh
    Department of Medicine, University of Rochester School of Medicine and Dentistry, and Department of Medicine, Rochester General Hospital, Rochester, New York, USA
    J Infect Dis 190:373-8. 2004
    ..Multivariate analysis found that low RSV-specific nasal IgA was an independently significant risk factor for RSV infection...
  42. ncbi request reprint Respiratory syncytial virus infection in elderly and high-risk adults
    A R Falsey
    General Hospital, Rochester, NY, USA
    Exp Lung Res 31:77. 2005
  43. ncbi request reprint Respiratory syncytial virus infection in older persons
    A R Falsey
    Department of Medicine, Rochester General Hospital, NY 14621, USA
    Vaccine 16:1775-8. 1998
    ..PFP-2, a candidate RSV subunit vaccine, has been evaluated in healthy and institutionalized elderly and been found to be safe and immunogenic...
  44. ncbi request reprint Hepatitis B immunization of healthy elderly adults: relationship between naïve CD4+ T cells and primary immune response and evaluation of GM-CSF as an adjuvant
    R J Looney
    Department of Medicine, University of Rochester School of Medicine and Dentistry, New York, USA
    J Clin Immunol 21:30-6. 2001
    ..73 due to the increase in age but only 0.40 due to the decrease in naive CD4 T cells. Thus, there was a large effect of age that could not be explained by the quantitative change in the naïve T-helper cells...
  45. ncbi request reprint Experimental infection of humans with A2 respiratory syncytial virus
    F Eun Hyung Lee
    Department of Medicine, University of Rochester School of Medicine and Dentistry, Box 689, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Antiviral Res 63:191-6. 2004
    ..This model provides a safe and efficient mechanism for proof-of-concept studies of anti-viral agents and RSV vaccines, as well as for investigation of immune responses to infection...
  46. ncbi request reprint Human infant respiratory syncytial virus (RSV)-specific type 1 and 2 cytokine responses ex vivo during primary RSV infection
    F Eun Hyung Lee
    David H Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Infect Dis 195:1779-88. 2007
    ..Illness severity is likely multifactorial; however, unlike other viral infections, both type 1 and type 2 cytokine responses have been implicated in severe disease...
  47. pmc Microneutralization assay for the measurement of neutralizing antibodies to human metapneumovirus
    Ann R Falsey
    Department of Medicine, Rochester General Hospital, Rochester, NY 14621 3001, USA
    J Clin Virol 46:314-7. 2009
    ..Human metapneumovirus (hMPV) is a newly discovered virus which causes respiratory illness in persons of all ages...
  48. ncbi request reprint Effect of aging on cytokine production in response to respiratory syncytial virus infection
    Richard J Looney
    Department of Medicine, University of Rochester School of Medicine and Dentistry, Box 695, 601 Elmwood Avenue, Rochester, NY 14642, USA
    J Infect Dis 185:682-5. 2002
    ..This defect in cellular immunity may be related to the increased morbidity observed with RSV infection in elderly persons...
  49. pmc Identification of and human serum reactogenicity to neutralizing epitopes within the central unglycosylated region of the respiratory syncytial virus attachment protein
    Yoshihiko Murata
    Division of Infectious Diseases, Department of Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 689, Rochester, NY 14642, USA
    Clin Vaccine Immunol 17:695-7. 2010
    ..In approximately 40% of hospitalized and outpatient adults infected with RSV subtype A, these contiguous residues are the target of > or =4-fold increases in IgG response between acute- and convalescent-phase sera...
  50. pmc Peak frequencies of circulating human influenza-specific antibody secreting cells correlate with serum antibody response after immunization
    Jessica L Halliley
    Division of Pulmonary and Critical Care Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Vaccine 28:3582-7. 2010
    ..The kinetics of this response and the relationship of circulating ASCs to protective antibody titers have not been completely explored...
  51. pmc Clinical and immunologic predictors of influenza illness among vaccinated older adults
    Zainab Shahid
    Division of Infectious Diseases, Department of Medicine, University of Connecticut Health Center, Farmington, CT, USA
    Vaccine 28:6145-51. 2010
    ..ILI subjects (p=0.03). The cell-mediated immune response to influenza distinguishes A/H3N2 LCI from other ILI in older adults, and suggests a link between cell-mediated immunity and influenza illness severity in vaccinated older adults...
  52. ncbi request reprint The balance between influenza- and RSV-specific CD4 T cells secreting IL-10 or IFNgamma in young and healthy-elderly subjects
    F Eun Hyung Lee
    David H Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA
    Mech Ageing Dev 126:1223-9. 2005
    ..A similar trend was seen for influenza. IFNgamma-secreting CD4 T cells contributed significantly more to anti-RSV than anti-influenza responses in both groups...
  53. pmc The diagnosis of viral respiratory disease in older adults
    H Keipp Talbot
    Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Clin Infect Dis 50:747-51. 2010
    ....
  54. doi request reprint New emerging technologies and the intradermal route: the novel way to immunize against influenza
    Ann R Falsey
    Rochester General Hospital, NY 14621, USA
    Vaccine 28:D24-32. 2010
    ..In addition, these methods of delivery may increase acceptability in children and persons with needle phobias, thus addressing some of the present barriers to influenza immunization...
  55. pmc RSV 2007: recent advances in respiratory syncytial virus research
    Whitney W Stevens
    The Carter Immunology Center, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
    Viral Immunol 21:133-40. 2008
    ..Additionally, there were two posters sessions displaying more than one hundred abstracts. The following summary provides a review of the proceedings from each session...
  56. doi request reprint Detection of genetic lineages of human metapneumovirus in Croatia during the winter season 2005/2006
    Suncanica Ljubin-Sternak
    Department of Virology, Collaborating Centre WHO for Virology, Croatian National Institute of Public Health, Zagreb, Croatia
    J Med Virol 80:1282-7. 2008
    ..It also showed the existence of two sublineages within the group B (B1 and B2) and three subclusters within lineage A (A1, A2a and A2b). Further molecular analysis revealed point mutations in HMPV strains of sublineage B1...
  57. ncbi request reprint Respiratory syncytial virus and other pneumoviruses: a review of the international symposium--RSV 2003
    Alexander C Schmidt
    Department of Pediatric Pulmonology and Immunology, Charite University Hospital, Berlin, Germany
    Virus Res 106:1-13. 2004
    ..Chanock Award for lifetime achievement in RSV research, an award named in honor of the person who started the field of RSV research by recovering the first human RS virus from infants with severe bronchiolitis in 1956...
  58. pmc Serosurvey of human metapneumovirus infection in Croatia
    Suncanica Ljubin Sternak
    Virology Department, Croatian, National Institute of Public Health, Zagreb, Croatia
    Croat Med J 47:878-81. 2006
    ..To assess the seroprevalence of human metapneumovirus (hMPV) in Croatia...

Research Grants2

  1. Sixth International Respiratory Syncytial Virus Symposium
    ANN FALSEY; Fiscal Year: 2007
    ..abstract_text> ..