Research Topics
| Francisco RobertSummaryCountry: USA Publications
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Detail Information
Publications
Comparison of biodistribution, dosimetry, and outcome from clinical trials of radionuclide-CC49 antibody therapyRuby Meredith
Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
Cancer Biother Radiopharm 18:393-404. 2003..Standardization and improved dosimetry may be helpful for comparison among patients in various studies and for establishing dose/toxicity relationships that are useful for predicting safe levels of radioimmunoconjugates...
A phase I study of larotaxel (XRP9881) administered in combination with carboplatin in chemotherapy-naïve patients with stage IIIB or stage IV non-small cell lung cancerFrancisco Robert
UAB Comprehensive Cancer Center, University of Alabama at Birmingham, 35294 3300, USA
Cancer Chemother Pharmacol 65:227-34. 2010....
Vorinostat in solid and hematologic malignanciesDavid Siegel
Hackensack University Medical Center, Hackensack, NJ, USA
J Hematol Oncol 2:31. 2009....
Phase I study of anti--epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancerF Robert
Division of Hematology Oncology, Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, and Birmingham Veterans Administration, 35294 3330, USA
J Clin Oncol 19:3234-43. 2001....
Sunitinib in combination with docetaxel in patients with advanced solid tumors: a phase I dose-escalation studyFrancisco Robert
Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA
Cancer Chemother Pharmacol 66:669-80. 2010..We assessed the maximum tolerated doses (MTDs), safety, pharmacokinetic profiles, and preliminary efficacy of sunitinib plus docetaxel in patients with advanced solid tumors...
The potential benefits of low-molecular-weight heparins in cancer patientsFrancisco Robert
Department of Medicine, Division of Hematology Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 352943300, USA
J Hematol Oncol 3:3. 2010..Such findings reinforce the importance of thromboprophylaxis with low-molecular-weight heparin in cancer patients...
Phase II study of docetaxel plus enoxaparin in chemotherapy-naive patients with metastatic non-small cell lung cancer: preliminary resultsFrancisco Robert
Department of Medicine, Division of Hematology Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, 1824 6th Avenue South, Birmingham, AL 35294 3300, USA
Lung Cancer 42:237-45. 2003..This preliminary data suggests that enoxaparin may prolong the time to progression, and therefore justify the continuation of this trial...
Chemotherapy tolerance after radioimmunotherapy with 90Y-CC49 monoclonal antibody in patients with advanced non-small cell lung cancer: clinical effects and hematologic toxicityFrancisco Robert
Department of Medicine, Division of Hematology Oncology and Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Cancer Biother Radiopharm 18:317-25. 2003..Taking into consideration the potential clinical relevance of integration of RIT with other treatment modalities, it is important to expand this clinical experience in order to support combined modality strategies...
Concurrent chemoradiation therapy with cisplatin and paclitaxel for locally advanced non-small cell lung cancer: long-term follow-up of a phase I trialFrancisco Robert
Department of Medicine, Division of Hematology Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35294 3300, USA
Lung Cancer 37:189-99. 2002..The activity observed with this regimen is particularly noteworthy when considering the advanced nature of these patients, and the fact that patients (N=18) with poor risk factors were included in the study...
Phase I/IIa study of cetuximab with gemcitabine plus carboplatin in patients with chemotherapy-naive advanced non-small-cell lung cancerFrancisco Robert
University of Alabama at Birmingham, Comprehensive Cancer Center, Birmingham, AL 35294 3300, USA
J Clin Oncol 23:9089-96. 2005..Secondary objectives were to gather preliminary evidence of efficacy including tumor response rate, time to progression, and overall survival...
Phase I study of 90Y-CC49 monoclonal antibody therapy in patients with advanced non-small cell lung cancer: effect of chelating agents and paclitaxel co-administrationAndres Forero
Department of Medicine, Comprehensive Cancer Center, University of Alabama at Birmingham, 1824 Sixth Avenue South, Birmingham, AL 35294 3300, USA
Cancer Biother Radiopharm 20:467-78. 2005....
Phase I/IIa study of cisplatin and gemcitabine as induction chemotherapy followed by concurrent chemoradiotherapy with gemcitabine and paclitaxel for locally advanced non-small-cell lung cancerStephen G Divers
University of Alabama at Birmingham, Birmingham, AL 35294-3300, USA
J Clin Oncol 23:6664-73. 2005..CONCLUSION: Additional investigation with the 3-week schedule is warranted in patients with a good performance status based on the safety profile and preliminary efficacy data observed in this study...
Improved prediction of myelotoxicity using a patient-specific imaging dose estimate for non-marrow-targeting (90)Y-antibody therapySui Shen
Department of Radiation Oncology, University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama 35249, USA
J Nucl Med 43:1245-53. 2002..These include (a) recycled (90)Y in bone/marrow space after (90)Y-antibody has been processed in the liver and (b) use of the marrow mass of Reference Man for individual patients...
Women with pathologic stage I, II, and III non-small cell lung cancer have better survival than menRobert James Cerfolio
Division of Cardiothoracic Surgery, University of Alabama at Birmingham, 1900 University Blvd, THT 712, Birmingham, AL 35294, USA
Chest 130:1796-802. 2006..National registry-based studies have shown gender disparity in clinicopathologic characteristics and in survival. This study evaluates the risk factors and trends of lung cancer between genders...
Phase II study of dose-intense chemotherapy with sequential topoisomerase-targeting regimens with irinotecan/oxaliplatin followed by etoposide/carboplatin in chemotherapy naive patients with extensive small cell lung cancerJoanne Rossman
Comprehensive Cancer Center, Division of Hematology Oncology, University of Alabama at Birmingham, 1802 Sixth Avenue South, NPCC 2540, Birmingham, AL 35294 3300, United States
Lung Cancer 72:219-23. 2011....
A randomized trial comparing immediate versus delayed treatment of anemia with once-weekly epoetin alfa in patients with non-small cell lung cancer scheduled to receive first-line chemotherapyJeffrey Crawford
Duke Medical Center, Durham, NC 27710, USA
J Thorac Oncol 2:210-20. 2007....
Non-small cell lung cancerDavid S Ettinger
J Natl Compr Canc Netw 6:228-69. 2008
Randomized phase II study of bortezomib alone and bortezomib in combination with docetaxel in previously treated advanced non-small-cell lung cancerMichael P Fanucchi
Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA
J Clin Oncol 24:5025-33. 2006..Additional investigation of bortezomib in NSCLC is warranted in combination with other drugs known to be active, or using different schedules...
Individualized patient dosing in phase I clinical trials: the role of escalation with overdose control in PNU-214936Jonathan D Cheng
Department of Medical Oncology, Fox Chase Cancer Center, 7701 Burholme Ave, Philadelphia, PA 19111, USA
J Clin Oncol 22:602-9. 2004....
Small cell lung cancerGregory P Kalemkerian
J Natl Compr Canc Netw 6:294-314. 2008
Non-small cell lung cancer clinical practice guidelines in oncologyDavid S Ettinger
J Natl Compr Canc Netw 4:548-82. 2006
Small cell lung cancer clinical practice guidelines in oncologyBruce E Johnson
J Natl Compr Canc Netw 4:602-22. 2006
