Matthew D Petroski

Summary

Affiliation: Rigel Pharmaceuticals
Country: USA

Publications

  1. ncbi Context of multiubiquitin chain attachment influences the rate of Sic1 degradation
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology 156 29, California Institute of Technology, 1200 E California Boulevard, Pasadena, CA 91125, USA
    Mol Cell 11:1435-44. 2003
  2. ncbi Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology, 156 29, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA
    Cell 123:1107-20. 2005
  3. ncbi Evaluation of a diffusion-driven mechanism for substrate ubiquitination by the SCF-Cdc34 ubiquitin ligase complex
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology, 156 29, California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA
    Mol Cell 24:523-34. 2006
  4. ncbi In vitro reconstitution of SCF substrate ubiquitination with purified proteins
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Methods Enzymol 398:143-58. 2005
  5. ncbi Redundant degrons ensure the rapid destruction of Sic1 at the G1/S transition of the budding yeast cell cycle
    Matthew D Petroski
    Howard Hughes Medical Institute and Division of Biology, California Institute of Technology, Pasadena, California 91125, USA
    Cell Cycle 2:410-1. 2003
  6. ncbi Function and regulation of cullin-RING ubiquitin ligases
    Matthew D Petroski
    Division of Biology and Howard Hughes Medical Institute, California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA
    Nat Rev Mol Cell Biol 6:9-20. 2005
  7. ncbi Substrate modification with lysine 63-linked ubiquitin chains through the UBC13-UEV1A ubiquitin-conjugating enzyme
    Matthew D Petroski
    Rigel Pharmaceuticals, Inc, South San Francisco, California 94080, USA
    J Biol Chem 282:29936-45. 2007

Collaborators

Detail Information

Publications7

  1. ncbi Context of multiubiquitin chain attachment influences the rate of Sic1 degradation
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology 156 29, California Institute of Technology, 1200 E California Boulevard, Pasadena, CA 91125, USA
    Mol Cell 11:1435-44. 2003
    ..Our results reveal that a single multiubiquitin chain can sustain a physiological turnover rate, but that chain position plays an unexpectedly significant role in the rate of proteasomal proteolysis...
  2. ncbi Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology, 156 29, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA
    Cell 123:1107-20. 2005
    ..We propose that the acidic loop favorably positions K48 of a substrate-linked ubiquitin to attack SCF bound Cdc34 approximately ubiquitin thioester and thereby enables processive synthesis of K48-linked ubiquitin chains by SCF-Cdc34...
  3. ncbi Evaluation of a diffusion-driven mechanism for substrate ubiquitination by the SCF-Cdc34 ubiquitin ligase complex
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology, 156 29, California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA
    Mol Cell 24:523-34. 2006
    ..We propose that interactions between Cdc34 approximately Ub and SCF directly activate ubiquitin transfer within a substrate-SCF-Cdc34 approximately Ub ternary complex...
  4. ncbi In vitro reconstitution of SCF substrate ubiquitination with purified proteins
    Matthew D Petroski
    Howard Hughes Medical Institute, Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Methods Enzymol 398:143-58. 2005
    ..Based on our experience in reconstituting Sic1 ubiquitination, we suggest some parameters to consider that should be generally applicable to the study of different SCF complexes and other ubiquitin ligases...
  5. ncbi Redundant degrons ensure the rapid destruction of Sic1 at the G1/S transition of the budding yeast cell cycle
    Matthew D Petroski
    Howard Hughes Medical Institute and Division of Biology, California Institute of Technology, Pasadena, California 91125, USA
    Cell Cycle 2:410-1. 2003
  6. ncbi Function and regulation of cullin-RING ubiquitin ligases
    Matthew D Petroski
    Division of Biology and Howard Hughes Medical Institute, California Institute of Technology, 1200 East California Boulevard, Pasadena, California 91125, USA
    Nat Rev Mol Cell Biol 6:9-20. 2005
    ..In this review, we focus on the composition, regulation and function of cullin-RING ligases, and describe how these enzymes can be characterized by a set of general principles...
  7. ncbi Substrate modification with lysine 63-linked ubiquitin chains through the UBC13-UEV1A ubiquitin-conjugating enzyme
    Matthew D Petroski
    Rigel Pharmaceuticals, Inc, South San Francisco, California 94080, USA
    J Biol Chem 282:29936-45. 2007
    ....