David O Williams

Summary

Affiliation: Rhode Island Hospital
Country: USA

Publications

  1. ncbi request reprint Outcomes of 6906 patients undergoing percutaneous coronary intervention in the era of drug-eluting stents: report of the DEScover Registry
    David O Williams
    Division of Cardiology, Department of Medicine Rhode Island Hospital, Medical School, Brown University, Providence, RI 02903, USA
    Circulation 114:2154-62. 2006
  2. ncbi request reprint Treatment delayed is treatment denied
    David O Williams
    Division of Cardiology, Department of Medicine, Brown Medical School, Providence, RI, USA
    Circulation 109:1806-8. 2004
  3. doi request reprint Outcomes of drug-eluting stents for protected left main coronary artery disease (from the Multicenter, United States DEScover registry)
    Joshua Leitner
    Division of Cardiology, Rhode Island Hospital, Brown University, Providence, USA
    Am J Cardiol 109:466-70. 2012
  4. pmc Temporal trends in patient-reported angina at 1 year after percutaneous coronary revascularization in the stent era: a report from the National Heart, Lung, and Blood Institute-sponsored 1997-2006 dynamic registry
    Lakshmi Venkitachalam
    Cardiovascular Institute, Department of Medicine, School of Medicine, Graduate School of Public Health, University of Pittsburgh, PA, USA
    Circ Cardiovasc Qual Outcomes 2:607-15. 2009
  5. pmc Twenty-year evolution of percutaneous coronary intervention and its impact on clinical outcomes: a report from the National Heart, Lung, and Blood Institute-sponsored, multicenter 1985-1986 PTCA and 1997-2006 Dynamic Registries
    Lakshmi Venkitachalam
    Cardiovascular Institute, Department of Medicine, School of Medicine, University of Pittsburgh, and Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Circ Cardiovasc Interv 2:6-13. 2009
  6. pmc Percutaneous coronary intervention of moderate to severe calcified coronary lesions: insights from the National Heart, Lung, and Blood Institute Dynamic Registry
    Sripal Bangalore
    Division of Cardiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Catheter Cardiovasc Interv 77:22-8. 2011
  7. doi request reprint Direct stenting compared to balloon predilation in drug-eluting stents: one-year outcomes from the DEScover Registry
    J Dawn Abbott
    Division of Cardiology, Rhode Island Hospital, Brown University, Providence, Rhode Island 02903, USA
    Catheter Cardiovasc Interv 79:84-9. 2012
  8. ncbi request reprint Gender-based outcomes in percutaneous coronary intervention with drug-eluting stents (from the National Heart, Lung, and Blood Institute Dynamic Registry)
    J Dawn Abbott
    Department of Cardiology, Rhode Island Hospital, Providence, Rhode Island, USA
    Am J Cardiol 99:626-31. 2007
  9. pmc Trends in major entry site complications from percutaneous coronary intervention (from the Dynamic Registry)
    Kristal Young
    Brown University Medical School, Department of Medicine, Rhode Island Hospital, Providence, Rhode Island
    Am J Cardiol 113:626-30. 2014
  10. ncbi request reprint Unrestricted use of drug-eluting stents compared with bare-metal stents in routine clinical practice: findings from the National Heart, Lung, and Blood Institute Dynamic Registry
    J Dawn Abbott
    Department of Cardiology, Rhode Island Hospital, Providence, Rhode Island, USA
    J Am Coll Cardiol 50:2029-36. 2007

Detail Information

Publications54

  1. ncbi request reprint Outcomes of 6906 patients undergoing percutaneous coronary intervention in the era of drug-eluting stents: report of the DEScover Registry
    David O Williams
    Division of Cardiology, Department of Medicine Rhode Island Hospital, Medical School, Brown University, Providence, RI 02903, USA
    Circulation 114:2154-62. 2006
    ..The DEScover Registry was designed to characterize patients selected for drug-eluting stents (DES) in routine clinical practice and their outcomes in the United States...
  2. ncbi request reprint Treatment delayed is treatment denied
    David O Williams
    Division of Cardiology, Department of Medicine, Brown Medical School, Providence, RI, USA
    Circulation 109:1806-8. 2004
  3. doi request reprint Outcomes of drug-eluting stents for protected left main coronary artery disease (from the Multicenter, United States DEScover registry)
    Joshua Leitner
    Division of Cardiology, Rhode Island Hospital, Brown University, Providence, USA
    Am J Cardiol 109:466-70. 2012
    ..25, confidence interval 0.09 to 0.67, p = 0.006). In conclusion, status after CABG rather than PLM location increases the risk of repeat revascularization with PCI in DES-treated patients...
  4. pmc Temporal trends in patient-reported angina at 1 year after percutaneous coronary revascularization in the stent era: a report from the National Heart, Lung, and Blood Institute-sponsored 1997-2006 dynamic registry
    Lakshmi Venkitachalam
    Cardiovascular Institute, Department of Medicine, School of Medicine, Graduate School of Public Health, University of Pittsburgh, PA, USA
    Circ Cardiovasc Qual Outcomes 2:607-15. 2009
    ..Little, however, is known about the temporal impact on patient-reported symptoms and quality of life after PCI...
  5. pmc Twenty-year evolution of percutaneous coronary intervention and its impact on clinical outcomes: a report from the National Heart, Lung, and Blood Institute-sponsored, multicenter 1985-1986 PTCA and 1997-2006 Dynamic Registries
    Lakshmi Venkitachalam
    Cardiovascular Institute, Department of Medicine, School of Medicine, University of Pittsburgh, and Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Circ Cardiovasc Interv 2:6-13. 2009
    ..Percutaneous coronary intervention (PCI) has undergone rapid progress, both in technology and adjunct therapy. However, documentation of long-term temporal trends in relation to contemporary practice is lacking...
  6. pmc Percutaneous coronary intervention of moderate to severe calcified coronary lesions: insights from the National Heart, Lung, and Blood Institute Dynamic Registry
    Sripal Bangalore
    Division of Cardiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Catheter Cardiovasc Interv 77:22-8. 2011
    ..To evaluate the efficacy and safety of drug eluting stents (DES) when compared with bare metal stents (BMS) in patients with moderate to severe calcified coronary lesions...
  7. doi request reprint Direct stenting compared to balloon predilation in drug-eluting stents: one-year outcomes from the DEScover Registry
    J Dawn Abbott
    Division of Cardiology, Rhode Island Hospital, Brown University, Providence, Rhode Island 02903, USA
    Catheter Cardiovasc Interv 79:84-9. 2012
    ..We sought to examine the determinants and outcomes of direct stenting (DS) compared to predilation with drug-eluting stents (DES)...
  8. ncbi request reprint Gender-based outcomes in percutaneous coronary intervention with drug-eluting stents (from the National Heart, Lung, and Blood Institute Dynamic Registry)
    J Dawn Abbott
    Department of Cardiology, Rhode Island Hospital, Providence, Rhode Island, USA
    Am J Cardiol 99:626-31. 2007
    ..01) and men (relative risk 0.68, 95% confidence interval 0.51 to 0.91, p = 0.001). In conclusion, the widespread use of DESs is safe and has decreased clinically driven revascularization compared with BMSs equally in women and men...
  9. pmc Trends in major entry site complications from percutaneous coronary intervention (from the Dynamic Registry)
    Kristal Young
    Brown University Medical School, Department of Medicine, Rhode Island Hospital, Providence, Rhode Island
    Am J Cardiol 113:626-30. 2014
    ..001) were low and decreased with time. The trend in less risk for MES in later time periods remained after adjustment. In conclusion, MES has decreased over time; however, opportunity for bleeding avoidance strategies still exists...
  10. ncbi request reprint Unrestricted use of drug-eluting stents compared with bare-metal stents in routine clinical practice: findings from the National Heart, Lung, and Blood Institute Dynamic Registry
    J Dawn Abbott
    Department of Cardiology, Rhode Island Hospital, Providence, Rhode Island, USA
    J Am Coll Cardiol 50:2029-36. 2007
    ..We investigated the effectiveness and safety of drug-eluting stents (DES) as used in routine clinical practice...
  11. ncbi request reprint Completeness of revascularization for multivessel coronary artery disease and its effect on one-year outcome: a report from the NHLBI Dynamic Registry
    Vankeepuram S Srinivas
    Division of Cardiology, Montefiore Medical Center, New York, NY 10461, USA
    J Interv Cardiol 20:373-80. 2007
    ..In conclusion, despite the presence of more unfavorable characteristics, patients undergoing TR demonstrate 1-year outcomes equivalent to those having CR, supporting its continued use in selected patients...
  12. pmc Clinical presentation and predictors of target vessel revascularization after drug-eluting stent implantation
    Hazem Al Muradi
    Division of Cardiology, Rhode Island Hospital, Brown University, 593 Eddy St, Providence, RI 02903, USA
    Cardiovasc Revasc Med 13:311-5. 2012
    ..We sought to examine the predictors and presentations of patients with clinically driven TVR after DES...
  13. ncbi request reprint Marked improvements in outcomes of contemporary percutaneous coronary intervention in patients with diabetes mellitus
    Andrew M Freeman
    Brown University, Rhode Island Hospital, Providence, Rhode Island 02903, USA
    J Interv Cardiol 19:475-82. 2006
    ..A combination of the use of stents and an increase in adjunctive medical therapy are likely responsible for the observed improvements in outcomes in contemporary PCI...
  14. ncbi request reprint Temporal variation in inhospital mortality with percutaneous coronary intervention: a report from the National Heart, Lung and Blood Institute Dynamic Registry
    Warren K Laskey
    Division of Cardiology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    Am Heart J 150:569-76. 2005
    ..Whether such time dependence extends to the risk of procedural-related mortality after percutaneous coronary intervention (PCI) is presently unknown...
  15. ncbi request reprint Recent trends in the percutaneous treatment of chronic total coronary occlusions
    J Dawn Abbott
    Division of Cardiology, Rhode Island Hospital, Brown University, Providence, Rhode Island, USA
    Am J Cardiol 97:1691-6. 2006
    ....
  16. ncbi request reprint Importance of the postdischarge interval in assessing major adverse clinical event rates following percutaneous coronary intervention
    Warren K Laskey
    Division of Cardiology, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131 0001, USA
    Am J Cardiol 95:1135-9. 2005
    ..Most postdischarge events derive from pathology related to the controlled vessel. A 30-day MACE rate may serve as a more comprehensive measurement of procedural outcome...
  17. ncbi request reprint Impact of coronary collaterals on outcome following percutaneous coronary intervention (from the National Heart, Lung, and Blood Institute Dynamic Registry)
    J Dawn Abbott
    Division of Cardiology, Brown University, Rhode Island Hospital, Providence, Rhode Island, USA
    Am J Cardiol 96:676-80. 2005
    ....
  18. ncbi request reprint Safety and efficacy of drug-eluting stents
    David O Williams
    Department of Cardiology, Rhode Island Hospital, Providence, Rhode Island, USA
    Rev Cardiovasc Med 6:S22-30. 2005
    ..In addition, specific patient subsets, including those patients with multivessel coronary disease, will be evaluated...
  19. ncbi request reprint Comparison of outcome in patients with ST-elevation versus non-ST-elevation acute myocardial infarction treated with percutaneous coronary intervention (from the National Heart, Lung, and Blood Institute Dynamic Registry)
    J Dawn Abbott
    Division of Cardiology, Rhode Island Hospital, Brown University, Providence, Rhode Island, USA
    Am J Cardiol 100:190-5. 2007
    ..At 1 year, associated co-morbidities were strongly associated with death and MI, whereas only angiographic characteristics predicted the need for repeat revascularization...
  20. ncbi request reprint Lessons learned in the drug-eluting stent era
    J Dawn Abbott
    Division of Cardiology, Rhode Island Hospital and Brown Medical School, Providence, RI, USA
    Am Heart Hosp J 5:169-72. 2007
  21. ncbi request reprint Contemporary percutaneous coronary intervention versus balloon angioplasty for multivessel coronary artery disease: a comparison of the National Heart, Lung and Blood Institute Dynamic Registry and the Bypass Angioplasty Revascularization Investigation (B
    V S Srinivas
    Department of Medicine, Division of Cardiovascular Medicine, Albert Einstein College of Medicine Montefiore Medical Center, Bronx, NY, USA
    Circulation 106:1627-33. 2002
    ..Patients having balloon angioplasty in the Bypass Angioplasty Revascularization Investigation (BARI) and those within the Dynamic Registry meeting BARI eligibility criteria were studied...
  22. ncbi request reprint Hyperbaric oxygen solution infused into the anterior interventricular vein at reperfusion reduces infarct size in swine
    Lynne L Johnson
    Division of Cardiology, Rhode Island Hospital, Brown University, Providence, Rhode Island 02903, USA
    Am J Physiol Heart Circ Physiol 287:H2234-40. 2004
    ..001), midmyocardial (P=0.03), and endocardial (P <0.001) layers in AO 0 min. AO infused into the AIV immediately at Rep diffuses into the RR and reduces IS by reducing Rep injury associated with neutrophil activation...
  23. pmc A comparison of bare-metal and drug-eluting stents for off-label indications
    Oscar C Marroquin
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, USA
    N Engl J Med 358:342-52. 2008
    ..Recent reports suggest that off-label use of drug-eluting stents is associated with an increased incidence of adverse events. Whether the use of bare-metal stents would yield different results is unknown...
  24. ncbi request reprint Thrombosis and drug-eluting stents: an objective appraisal
    David R Holmes
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55955, USA
    J Am Coll Cardiol 50:109-18. 2007
    ....
  25. ncbi request reprint A decade of improvement in the clinical outcomes of percutaneous coronary intervention for multivessel coronary artery disease
    V S Srinivas
    Circulation 107:e88. 2003
  26. ncbi request reprint The SIRIUS-DIRECT trial: a multi-center study of direct stenting using the sirolimus-eluting stent in patients with de novo native coronary artery lesions
    Jeffrey W Moses
    New York Presbyterian Hospital, Columbia University and Cardiovascular Research Foundation, New York, USA
    Catheter Cardiovasc Interv 70:505-12. 2007
    ..To assess the safety and efficacy of direct stenting using the sirolimus-eluting BX Velocitytrade mark stent in patients with coronary lesions...
  27. ncbi request reprint Comparison of in-hospital and one-year outcomes in patients with and without diabetes mellitus undergoing percutaneous catheter intervention (from the National Heart, Lung, and Blood Institute Dynamic Registry)
    Warren K Laskey
    University of Maryland School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 90:1062-7. 2002
    ..73, 95% CI 0.61 to 0.88; adjusted RR in patients with diabetes 1.20, 95% CI 0.88 to 1.65). Beta blockers at the time of hospital discharge were significantly associated with reduced mortality rates at 1 year in both groups...
  28. ncbi request reprint Et tu, bare metal stent?
    David O Williams
    Circulation 116:2363-5. 2007
  29. doi request reprint The problem with composite end points in cardiovascular studies: the story of major adverse cardiac events and percutaneous coronary intervention
    Kevin E Kip
    College of Nursing, University of South Florida, Tampa, Florida 33612, USA
    J Am Coll Cardiol 51:701-7. 2008
    ..Our purpose was to evaluate the heterogeneity and validity of composite end points, major adverse cardiac events (MACE) in particular, in cardiology research...
  30. ncbi request reprint Intracoronary brachytherapy: past, present, and future
    David O Williams
    Circulation 105:2699-700. 2002
  31. ncbi request reprint Outcomes and complications associated with off-label and untested use of drug-eluting stents
    Nirat Beohar
    Northwestern University Feinberg School of Medicine, Chicago, Ill, USA
    JAMA 297:1992-2000. 2007
    ..Limited data exist regarding use of drug-eluting stents outside of approved indications in real-world settings...
  32. ncbi request reprint Access site hematoma requiring blood transfusion predicts mortality in patients undergoing percutaneous coronary intervention: data from the National Heart, Lung, and Blood Institute Dynamic Registry
    Leonid Yatskar
    Department of Cardiology, New York University, New York, New York, USA
    Catheter Cardiovasc Interv 69:961-6. 2007
    ..To determine both the etiology of and outcomes associated with access site hematoma requiring transfusion (HRT) in patients undergoing percutaneous coronary intervention (PCI)...
  33. ncbi request reprint Comparison of in-hospital and one-year outcomes in patients with left ventricular ejection fractions <or=40%, 41% to 49%, and >or=50% having percutaneous coronary revascularization
    Paul C Keelan
    Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Cardiol 91:1168-72. 2003
    ..Thus, significant LV dysfunction was still associated with increased in-hospital and 1-year mortality in patients having contemporary PCI...
  34. ncbi request reprint Angina 1 year after percutaneous coronary intervention: a report from the NHLBI Dynamic Registry
    Richard Holubkov
    Department of Epidemiology, Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am Heart J 144:826-33. 2002
    ..As percutaneous coronary intervention (PCI) is most commonly performed for relief of angina, it is important to identify factors associated with recurrence of anginal symptoms...
  35. ncbi request reprint Impact of age on procedural and 1-year outcome in percutaneous transluminal coronary angioplasty: a report from the NHLBI Dynamic Registry
    Howard A Cohen
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Am Heart J 146:513-9. 2003
    ..As PCI technology evolves and the US population becomes proportionally older, assessment of PCI in older age groups is essential...
  36. ncbi request reprint A twist in our understanding of enzyme elevation after coronary intervention
    David O Williams
    J Am Coll Cardiol 42:1906-8. 2003
  37. ncbi request reprint Improved outcomes for women undergoing contemporary percutaneous coronary intervention: a report from the National Heart, Lung, and Blood Institute Dynamic registry
    Alice K Jacobs
    Evans Memorial Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA
    J Am Coll Cardiol 39:1608-14. 2002
    ..The goal of this study was to determine whether women undergoing contemporary percutaneous coronary intervention (PCI) remain at increased risk in comparison with men and whether the outcomes in women have improved...
  38. ncbi request reprint Comparison of patients undergoing enhanced external counterpulsation and percutaneous coronary intervention for stable angina pectoris
    Richard Holubkov
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 89:1182-6. 2002
    ..Although PCI was associated with substantially lower rates of 1-year symptoms, EECP may be a safe treatment option for selected patients with obstructive coronary disease...
  39. ncbi request reprint Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery
    Jeffrey W Moses
    Cardiovascular Research Foundation and Lenox Hill Heart and Vascular Institute of New York, New York 10021, USA
    N Engl J Med 349:1315-23. 2003
    ..Preliminary reports of studies involving simple coronary lesions indicate that a sirolimus-eluting stent significantly reduces the risk of restenosis after percutaneous coronary revascularization...
  40. ncbi request reprint [Universal definition of the myocardial infarction]
    Kristian Thygesen
    Department of Medicine and Cardiology, Aarhus University Hospital, Dania
    Kardiol Pol 66:47-62. 2008
  41. ncbi request reprint What to do with patients receiving long-term clopidogrel: reload or relax?
    David O Williams
    Circulation 118:1219-22. 2008
  42. ncbi request reprint Thrombolytic therapy vs primary percutaneous coronary intervention for myocardial infarction in patients presenting to hospitals without on-site cardiac surgery: a randomized controlled trial
    Thomas Aversano
    Blalock 524, Johns Hopkins Hospital, 600 N Wolfe St, Baltimore, MD 21210, USA
    JAMA 287:1943-51. 2002
    ..Because PCI is often limited to hospitals that have on-site cardiac surgery programs, most acute MI patients do not have access to this therapy...
  43. ncbi request reprint Relation of percutaneous coronary intervention of complex lesions to clinical outcomes (from the NHLBI Dynamic Registry)
    Robert L Wilensky
    Cardiovascular Division, University of Pennsylvania, Philadelphia 19104, USA
    Am J Cardiol 90:216-21. 2002
    ..An increased in-hospital adverse clinical event rate was independently noted for thrombotic, bifurcation, and calcified lesions, and bifurcation lesions had worse long-term event rates...
  44. ncbi request reprint Bifurcation intervention: is it crush time yet?
    David O Williams
    J Am Coll Cardiol 46:621-4. 2005
  45. doi request reprint 2007 focused update of the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice guidelines
    Spencer B King
    J Am Coll Cardiol 51:172-209. 2008
  46. ncbi request reprint The impact of ejection fraction on outcomes after percutaneous coronary intervention in patients with congestive heart failure: an analysis of the National Heart, Lung, and Blood Institute Percutaneous Transluminal Coronary Angioplasty Registry and Dynami
    Elizabeth M Holper
    University of Chicago, Chicago, IL 60637, USA
    Am Heart J 151:69-75. 2006
    ..We studied the outcomes of patients with CHF who underwent PCI in the National Heart, Lung, and Blood Institute-sponsored Percutaneous Transluminal Coronary Angioplasty (PTCA) and Dynamic registries...
  47. ncbi request reprint Outcome of percutaneous coronary intervention in unstable angina pectoris versus stable angina pectoris in two different time periods
    Srihari S Naidu
    The Cardiovascular Division, Weill Cornell Medical Center, New York, New York, USA
    Am J Cardiol 98:447-52. 2006
    ....
  48. ncbi request reprint Ethnic differences in the presentation, treatment strategy, and outcomes of percutaneous coronary intervention (a report from the National Heart, Lung, and Blood Institute Dynamic Registry)
    James Slater
    New York University Medical Center, New York, New York 1016 649, USA
    Am J Cardiol 92:773-8. 2003
    ....
  49. ncbi request reprint Development of systems of care for ST-elevation myocardial infarction patients: the primary percutaneous coronary intervention (ST-elevation myocardial infarction-receiving) hospital perspective
    Christopher B Granger
    Circulation 116:e55-9. 2007
  50. ncbi request reprint Comparison of the efficacy of direct coronary stenting with sirolimus-eluting stents versus stenting with predilation by intravascular ultrasound imaging (from the DIRECT trial)
    Atsushi Hirohata
    Center for Research in Cardiovascular Intervention, Stanford University, Stanford, California, USA
    Am J Cardiol 98:1464-7. 2006
    ..This strategy appears to be associated with less neointimal hyperplasia near the distal stent edge...
  51. ncbi request reprint Modeling and risk prediction in the current era of interventional cardiology: a report from the National Heart, Lung, and Blood Institute Dynamic Registry
    David R Holmes
    Mayo Clinic, 200 First Street SW, Rochester, Minn 55905, USA
    Circulation 107:1871-6. 2003
    ..Validation of in-hospital mortality models after percutaneous coronary interventions using multicenter data remains limited...
  52. ncbi request reprint The truth and consequences of the COURAGE trial
    Dean J Kereiakes
    Christ Hospital Heart and Vascular Center the Lindner Research Center, Cincinnati, Ohio 45219, USA
    J Am Coll Cardiol 50:1598-603. 2007
    ..An in-depth analysis of the COURAGE trial design and execution is provided...
  53. ncbi request reprint Universal definition of myocardial infarction
    Kristian Thygesen
    Circulation 116:2634-53. 2007
  54. ncbi request reprint 2007 Focused Update of the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: 2007 Writing Group to Review New Evidence an
    Spencer B King
    Circulation 117:261-95. 2008