Research Topics
| J E UdelsonSummaryAffiliation: Rhode Island Hospital Country: USA Publications
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Detail Information
Publications
Therapeutic angiogenesis with recombinant fibroblast growth factor-2 improves stress and rest myocardial perfusion abnormalities in patients with severe symptomatic chronic coronary artery diseaseJ E Udelson
Cardiac Imaging Core Laboratory, Division of Cardiology, New England Medical Center Hospitals Tufts University School of Medicine, Boston, MA 02111, USA
Circulation 102:1605-10. 2000..We report the effects of the administration of recombinant fibroblast growth factor-2 (rFGF-2) protein on myocardial perfusion using single photon emission computed tomography imaging in humans with advanced coronary disease...
Acute hemodynamic effects of conivaptan, a dual V(1A) and V(2) vasopressin receptor antagonist, in patients with advanced heart failureJ E Udelson
Division of Cardiology, New England Medical Center Hospitals Tufts University School of Medicine, Boston, Massachusetts, USA
Circulation 104:2417-23. 2001..Inhibiting the action of vasopressin may be beneficial in patients with heart failure...
Myocardial perfusion imaging for evaluation and triage of patients with suspected acute cardiac ischemia: a randomized controlled trialJames E Udelson
Division of Clinical Care Research, Tufts New England Medical Center, 750 Washington St, Box 70, Boston, MA 02111, USA
JAMA 288:2693-700. 2002....
Radionuclide imaging in heart failure: assessing etiology and outcomes and implications for managementJames E Udelson
Division of Cardiology, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, Mass 02111, USA
J Nucl Cardiol 9:40S-52S. 2002
Heart failure etiology affects peripheral vascular endothelial function after cardiac transplantationA R Patel
Cardiovascular Imaging and Hemodynamic Laboratory, New England Medical Center Hospitals Inc, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
J Am Coll Cardiol 37:195-200. 2001..These findings indicate that cardiac transplantation corrects peripheral endothelial function for patients without ischemic heart disease, but not in those with prior atherosclerotic coronary disease...
Effects of amlodipine on exercise tolerance, quality of life, and left ventricular function in patients with heart failure from left ventricular systolic dysfunctionJ E Udelson
Division of Cardiology, Department of Medicine, New England Medical Center, Boston, MA 02111, USA
Am Heart J 139:503-10. 2000....
Clinical trials in coronary angiogenesis: issues, problems, consensus: An expert panel summaryM Simons
Angiogenesis Research Center, BIDMC, Harvard Medical School, Boston, MA, USA
Circulation 102:E73-86. 2000....
Bulls-eye display and quantitation of myocardial perfusion defects using three-dimensional contrast echocardiographyJ Yao
Tufts NEMC, Box 32, 750 Washington St, Boston, MA 02111, USA
Echocardiography 18:581-8. 2001..1 +/- 2.4%). We conclude that bulls-eye display of contrast 3-D MCE demonstrates the site and extent of perfusion abnormalities in an easily appreciable manner. It also allows fast and accurate assessment of endangered myocardium...
Radionuclide imaging in risk assessment after acute coronary syndromesJ E Udelson
Division of Cardiology, Tufts-New England Medical Center Hospitals, Tufts University School of Medicine, Boston, Massachusetts, USA
Heart 90:v16-25. 2004
Effects of losartan and captopril on left ventricular volumes in elderly patients with heart failure: results of the ELITE ventricular function substudyM A Konstam
Tufts University, New England Medical Center, Boston, MA 02111, USA
Am Heart J 139:1081-7. 2000....
Peripheral vascular endothelial function testing as a noninvasive indicator of coronary artery diseaseJ T Kuvin
Department of Medicine/Division of Cardiology, New England Medical Center Hospitals, Tufts University School of Medicine, Boston, Massachusetts, USA
J Am Coll Cardiol 38:1843-9. 2001..Further standardization of BAUS is required, however, before specific cut-points for excluding CAD can be established...
American Society of Nuclear Cardiology position statement on radionuclide imaging in patients with suspected acute ischemic syndromes in the emergency department or chest pain centerFrans J Th Wackers
J Nucl Cardiol 9:246-50. 2002
Acute resting myocardial perfusion imaging in patients with diabetes mellitus: results from the Emergency Room Assessment of Sestamibi for Evaluation of Chest Pain (ERASE Chest Pain) trialAthanasios Kapetanopoulos
Hnry Low Heart Center for the Division of Cardiology, Hartford Hospital, Hartford, CT 06102, USA
J Nucl Cardiol 11:570-7. 2004..0002 for patients without DM and P = .35 for interaction of diabetes and RR reduction). CONCLUSIONS: Acute resting MPI with Tc-99m sestamibi is associated with improved triage decision making in symptomatic ED patients with diabetes...
Clinical implications of QRS duration in patients hospitalized with worsening heart failure and reduced left ventricular ejection fractionNorman C Wang
Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
JAMA 299:2656-66. 2008..Hospitalization for heart failure is associated with high postdischarge mortality and morbidity. The predictive value of the QRS duration during admission for heart failure has not been well studied...
MIBG imaging for selecting heart failure patients for defibrillator therapy: a first stepColin D Shafer
J Nucl Cardiol 10:208-10. 2003
Evaluation of a new ultrasound contrast agent (AI-700) using two-dimensional and three-dimensional imaging during acute ischemiaJiefen Yao
Cardiovascular Imaging and Hemodynamic Laboratory Division of Cardiology, Department of Medicine, New England Medical Center, Tufts University School of Medicine, Boston, USA
J Am Soc Echocardiogr 15:686-94. 2002....
Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure: the EVEREST Clinical Status TrialsMihai Gheorghiade
Division of Cardiology, Northwestern University, Feinberg School of Medicine, Chicago, Ill 60611, USA
JAMA 297:1332-43. 2007..Heart failure causes more than 1 million US hospitalizations yearly, mostly related to congestion. Tolvaptan, an oral, nonpeptide, selective vasopressin V2-receptor antagonist, shows promise in this condition...
Randomized, controlled evaluation of short- and long-term benefits of heart failure disease management within a diverse provider network: the SPAN-CHF trialCarey Kimmelstiel
Division of Cardiology, Tufts-New England Medical Center, and Tufts University School of Medicine, Boston, Mass 02111, USA
Circulation 110:1450-5. 2004..Longer-term benefit likely requires more active chronic intervention, even among patients who appear clinically stable...
Quantitative instruments for predicting risk ... and benefitJames E Udelson
J Am Coll Cardiol 45:730-2. 2005
Screening the population for coronary artery disease: is it like screening for cancer?Prem Soman
J Nucl Cardiol 12:145-7. 2005
Rationale and design of the multicenter, randomized, double-blind, placebo-controlled study to evaluate the Efficacy of Vasopressin antagonism in Heart Failure: Outcome Study with Tolvaptan (EVEREST)Mihai Gheorghiade
Division of Cardiology, Northwestern Feinberg School of Medicine, Chicago, IL, USA
J Card Fail 11:260-9. 2005..The results of EVEREST will determine whether these effects translate into improved clinical outcomes...
Metabolic imaging with beta-methyl-p-[(123)I]-iodophenyl-pentadecanoic acid identifies ischemic memory after demand ischemiaVasken Dilsizian
Division of Nuclear Medicine, University of Maryland Hospital and School of Medicine, Baltimore, MD 21201 1595, USA
Circulation 112:2169-74. 2005..We hypothesized that a branched-chain fatty acid, beta-methyl-p-[(123)I]-iodophenyl-pentadecanoic acid (BMIPP), might identify the presence of myocardial ischemia late after demand ischemia at rest up to 30 hours later...
A head-to-head comparison of infusion and bolus doses of adenosine for stress myocardial contrast echocardiographyHans Joachim Nesser
IInd Department of Medicine, Cardiology, KH der Elisabethinen Hospital, Linz, Austria
Echocardiography 23:483-9. 2006..This study was a head-to-head, intraindividual comparison of the diagnostic accuracy and side effect profile of bolus and infusion administration of adenosine for stress myocardial contrast echocardiography (MCE)...
Assessment and key targets for therapy in the post-myocardial infarction patient with left ventricular dysfunctionJames D Flaherty
Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
Am J Cardiol 102:5G-12G. 2008..This review describes the current modalities for assessing the key pathophysiologic targets in post-MI patients with LVD and the effects of systemic factors on cardiac disease severity...
Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome TrialMarvin A Konstam
Division of Cardiology, Tufts New England Medical Center, Boston, Mass, USA
JAMA 297:1319-31. 2007..Vasopressin mediates fluid retention in heart failure. Tolvaptan, a vasopressin V2 receptor blocker, shows promise for management of heart failure...
Vascular endothelial dysfunction is associated with reversible myocardial perfusion defects in the absence of obstructive coronary artery diseasePrem Soman
Division of Cardiology, Tufts New England Medical Center, Boston, Mass, USA
J Nucl Cardiol 13:756-60. 2006..Recent evidence suggests that coronary endothelial dysfunction might play a role in the pathogenesis of these defects...
The historical and conceptual evolution of radionuclide assessment of myocardial viabilityJames E Udelson
Division of Cardiology, Tufts-New England Medical Center, Boston, MA 02111, USA
J Nucl Cardiol 11:318-34. 2004
Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: a meta-analysisKevin C Allman
Concord Hospital, Concord NSW, Australia
J Am Coll Cardiol 39:1151-8. 2002....
Noninvasive assessment of left ventricular remodeling: concepts, techniques, and implications for clinical trialsInder S Anand
Division of Cardiology, University of Minnesota Medical School and Veterans Administration Medical Center, Minneapolis, MN 55417, USA
J Card Fail 8:S452-64. 2002..CONCLUSIONS: Each of these techniques carries specific advantages and disadvantages for assessment of remodeling in individual patients and in the context of large-scale clinical trials...
Relation between left ventricular remodeling and clinical outcomes in heart failure patients with left ventricular systolic dysfunctionJames E Udelson
Division of Cardiology, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, MA, USA
J Card Fail 8:S465-71. 2002....
34th Bethesda Conference: Executive summary--can atherosclerosis imaging techniques improve the detection of patients at risk for ischemic heart disease?Allen J Taylor
Cardiovascular Research, US Army Cardiology Service, Walter Reed Army Medical Center, WRAMC Building 2, Room 4A, 6900 Georgia Avenue NW, Washington, DC 20307, 5001
J Am Coll Cardiol 41:1860-2. 2003
Primary prevention of sudden death as a novel treatment strategy in hypertrophic cardiomyopathyBarry J Maron
The Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 E 28th St, Suite 60, Minneapolis, Minn 55407, USA
Circulation 107:2872-5. 2003
ACC/AHA/ASNC guidelines for the clinical use of cardiac radionuclide imaging--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASNC Committee to Revise the 1995 GuideliFrancis J Klocke
Circulation 108:1404-18. 2003
ACC/AHA/ASNC guidelines for the clinical use of cardiac radionuclide imaging--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASNC Committee to Revise the 1995 GuideliFrancis J Klocke
J Am Coll Cardiol 42:1318-33. 2003
New concepts in post-infarction ventricular remodelingJames E Udelson
Division of Cardiology, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA
Rev Cardiovasc Med 4:S3-12. 2003..It is also demonstrated that drug therapies that slow or reverse the remodeling process appear to have favorable natural history effects in the short term as well as during long-term therapy...
Ventricular remodeling in heart failure: a credible surrogate endpointMarvin A Konstam
J Card Fail 9:350-3. 2003
Role of beta-blocker therapy in the post-myocardial infarction patient with and without left ventricular dysfunctionGregg C Fonarow
Rev Cardiovasc Med 4:S54-9. 2003
Ventricular remodeling in heart failure and the effect of beta-blockadeJames E Udelson
Division of Cardiology, Tufts New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA
Am J Cardiol 93:43B-8B. 2004..Differences in their effect on remodeling have been recently shown among the beta-blockers. Several studies and a meta-analysis suggest that carvedilol may be more favorable to outcome, having the most effect on LV remodeling...
Prevalence, clinical significance, and natural history of left ventricular apical aneurysms in hypertrophic cardiomyopathyMartin S Maron
Division of Cardiology, Hypertrophic Cardiomyopathy Center, Tufts Medical Center, Boston, Massachussetts 02111, USA
Circulation 118:1541-9. 2008..This study reports the prevalence, morphology, clinical course, and management of an underrecognized subgroup of HCM patients with left ventricular apical aneurysms...
