J Lau

Summary

Affiliation: Rhode Island Hospital
Country: USA

Publications

  1. ncbi request reprint Comparison of evidence of treatment effects in randomized and nonrandomized studies
    J P Ioannidis
    Division of Clinical Care Research, New England Medical Center, Box 63, 750 Washington St, Boston, MA 02111, USA
    JAMA 286:821-30. 2001
  2. ncbi request reprint Diagnosing acute cardiac ischemia in the emergency department: a systematic review of the accuracy and clinical effect of current technologies
    J Lau
    Evidence Based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02111, USA
    Ann Emerg Med 37:453-60. 2001
  3. ncbi request reprint Accuracy of imaging technologies in the diagnosis of acute cardiac ischemia in the emergency department: a meta-analysis
    J P Ioannidis
    Evidence-based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02115, USA
    Ann Emerg Med 37:471-7. 2001
  4. ncbi request reprint Accuracy of biomarkers to diagnose acute cardiac ischemia in the emergency department: a meta-analysis
    E M Balk
    Evidence-based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02115, USA
    Ann Emerg Med 37:478-94. 2001
  5. ncbi request reprint Accuracy and clinical effect of out-of-hospital electrocardiography in the diagnosis of acute cardiac ischemia: a meta-analysis
    J P Ioannidis
    Evidence-based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02115, USA
    Ann Emerg Med 37:461-70. 2001
  6. ncbi request reprint Technical report: evidence for the diagnosis and treatment of acute uncomplicated sinusitis in children: a systematic overview
    J P Ioannidis
    New England Medical Center Evidence-based Practice Center, Boston, Massachusetts, USA
    Pediatrics 108:E57. 2001
  7. ncbi request reprint Meta-analysis of diagnostic tests for acute sinusitis
    E A Engels
    Division of Clinical Care Research, Department of Medicine, New England Medical Center, Tufts University School of Medicine, 750 Washington Street, Boston, MA 02111, USA
    J Clin Epidemiol 53:852-62. 2000
  8. ncbi request reprint Summing up evidence: one answer is not always enough
    J Lau
    Division of Clinical Care Research, New England Medical Center Hospitals, Boston, MA 02111, USA
    Lancet 351:123-7. 1998
  9. pmc Strategies for diagnosing and treating suspected acute bacterial sinusitis: a cost-effectiveness analysis
    E M Balk
    Evidence-based Practice Center, Division of Clinical Care Research, Tufts University School of Medicine, New England Medical Center, Boston, MA 02111, USA
    J Gen Intern Med 16:701-11. 2001
  10. ncbi request reprint Balancing the benefits of primary angioplasty against the benefits of thrombolytic therapy for acute myocardial infarction: the importance of timing
    D M Kent
    New England Medical Center Tufts University School of Medicine, Boston, Mass, USA
    Eff Clin Pract 4:214-20. 2001

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Comparison of evidence of treatment effects in randomized and nonrandomized studies
    J P Ioannidis
    Division of Clinical Care Research, New England Medical Center, Box 63, 750 Washington St, Boston, MA 02111, USA
    JAMA 286:821-30. 2001
    ..There is substantial debate about whether the results of nonrandomized studies are consistent with the results of randomized controlled trials on the same topic...
  2. ncbi request reprint Diagnosing acute cardiac ischemia in the emergency department: a systematic review of the accuracy and clinical effect of current technologies
    J Lau
    Evidence Based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02111, USA
    Ann Emerg Med 37:453-60. 2001
    ..Accurate diagnosis and triage of patients with ACI in the emergency department should increase survival for these patients and reduce unnecessary hospital admissions...
  3. ncbi request reprint Accuracy of imaging technologies in the diagnosis of acute cardiac ischemia in the emergency department: a meta-analysis
    J P Ioannidis
    Evidence-based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02115, USA
    Ann Emerg Med 37:471-7. 2001
    ..More evidence should be accumulated on their performance specifically in the ED setting...
  4. ncbi request reprint Accuracy of biomarkers to diagnose acute cardiac ischemia in the emergency department: a meta-analysis
    E M Balk
    Evidence-based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02115, USA
    Ann Emerg Med 37:478-94. 2001
    ..Further high-quality studies are needed on the clinical effect of using biomarkers for patients with ACI in the ED and on optimal timing of serial testing and in combination with other tests...
  5. ncbi request reprint Accuracy and clinical effect of out-of-hospital electrocardiography in the diagnosis of acute cardiac ischemia: a meta-analysis
    J P Ioannidis
    Evidence-based Practice Center, Division of Clinical Care Research, New England Medical Center, Boston, MA 02115, USA
    Ann Emerg Med 37:461-70. 2001
    ..Out-of-hospital thrombolysis achieves time savings and improves short-term mortality, but the effect on long-term mortality is unknown...
  6. ncbi request reprint Technical report: evidence for the diagnosis and treatment of acute uncomplicated sinusitis in children: a systematic overview
    J P Ioannidis
    New England Medical Center Evidence-based Practice Center, Boston, Massachusetts, USA
    Pediatrics 108:E57. 2001
    ..Diagnostic modalities show poor concordance, and treatment options are based on inadequate data. More evidence is needed for defining the optimal treatment and diagnostic methods for this common condition...
  7. ncbi request reprint Meta-analysis of diagnostic tests for acute sinusitis
    E A Engels
    Division of Clinical Care Research, Department of Medicine, New England Medical Center, Tufts University School of Medicine, 750 Washington Street, Boston, MA 02111, USA
    J Clin Epidemiol 53:852-62. 2000
    ..In conclusion, acute sinusitis is common among symptomatic patients. Radiography and clinical evaluation (especially risk scores) appear to provide useful information for diagnosis of sinusitis...
  8. ncbi request reprint Summing up evidence: one answer is not always enough
    J Lau
    Division of Clinical Care Research, New England Medical Center Hospitals, Boston, MA 02111, USA
    Lancet 351:123-7. 1998
    ..Here we take a more rounded approach to meta-analyses, arguing that their strengths outweigh their weaknesses, although the latter must not be brushed aside...
  9. pmc Strategies for diagnosing and treating suspected acute bacterial sinusitis: a cost-effectiveness analysis
    E M Balk
    Evidence-based Practice Center, Division of Clinical Care Research, Tufts University School of Medicine, New England Medical Center, Boston, MA 02111, USA
    J Gen Intern Med 16:701-11. 2001
    ..Newer, expensive antibiotics are of limited value. Additional testing is not cost-effective. Further studies are needed to find an accurate,low-cost diagnostic test for acute bacterial sinusitis...
  10. ncbi request reprint Balancing the benefits of primary angioplasty against the benefits of thrombolytic therapy for acute myocardial infarction: the importance of timing
    D M Kent
    New England Medical Center Tufts University School of Medicine, Boston, Mass, USA
    Eff Clin Pract 4:214-20. 2001
    ..However, fewer than 20% of U.S. hospitals have facilities to perform PTCA and many clinicians must choose between immediate thrombolytic therapy and delayed PTCA...
  11. pmc Evolution of treatment effects over time: empirical insight from recursive cumulative metaanalyses
    J Ioannidis
    Division of Clinical Care Research, New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Proc Natl Acad Sci U S A 98:831-6. 2001
    ..Early wide oscillations in the evolution of the treatment effect for specific interventions may sometimes signal further major changes in the future...
  12. ncbi request reprint Efficacy of quinolone prophylaxis in neutropenic cancer patients: a meta-analysis
    E A Engels
    Tupper Research Institute, Department of Medicine, New England Medical Center, Boston, MA 02111, USA
    J Clin Oncol 16:1179-87. 1998
    ..To perform a meta-analysis to estimate the efficacy of quinolone antibiotics in preventing infections, fevers, and deaths among cancer patients neutropenic following chemotherapy...
  13. pmc Typhoid fever vaccines: a meta-analysis of studies on efficacy and toxicity
    E A Engels
    Department of Medicine, New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    BMJ 316:110-6. 1998
    ..To estimate the efficacy and toxicity of typhoid fever vaccines...
  14. ncbi request reprint Effect of biocompatibility of hemodialysis membranes on mortality in acute renal failure: a meta-analysis
    B L Jaber
    Department of Medicine, New England Medical Center Hospitals, Boston, MA 02111, USA
    Clin Nephrol 57:274-82. 2002
    ....
  15. ncbi request reprint The Kidney Disease: improving Global Outcomes website: comparison of guidelines as a tool for harmonization
    H Vanbelleghem
    University Hospital, Gent, Belgium
    Kidney Int 71:1054-61. 2007
    ..The tables displayed on the website offer a basis for structuring this process, a procedure which has recently been initiated by a body composed of the five guideline development groups...
  16. ncbi request reprint Efficacy of Haemophilus influenzae type b vaccination of children: a meta-analysis
    C O Obonyo
    Centre for Vector Biology and Control Research, Kenya Medical Research Institute, PO Box 1578, Kisumu, 40100, Kenya
    Eur J Clin Microbiol Infect Dis 25:90-7. 2006
    ....
  17. ncbi request reprint Introduction to cumulative meta-analysis in dentistry: lessons learned from undertaking a cumulative meta-analysis in periodontology
    D R Moles
    Eastman Dental Institute for Oral Health Care Science, University College London, London, WC1X 8LD, UK
    J Dent Res 84:345-9. 2005
    ..This represents a potential source of bias. Investigators are encouraged to consider their trials as part of an information continuum and to report sufficient detail to permit the trials' incorporation into subsequent syntheses...
  18. ncbi request reprint A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. Treatments for myocardial infarction
    E M Antman
    Department of Medicine, Brigham and Women's Hospital, Boston, MA
    JAMA 268:240-8. 1992
    ....
  19. ncbi request reprint Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for lower respiratory tract infections
    D G Contopoulos-Ioannidis
    Clinical Trials and Evidence-Based Medicine Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina 45110, Greece
    J Antimicrob Chemother 48:691-703. 2001
    ....
  20. ncbi request reprint Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for upper respiratory tract infections
    J P Ioannidis
    Clinical Trials and Evidence-Based Medicine Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina 45110, Greece
    J Antimicrob Chemother 48:677-89. 2001
    ..Convenience of dosing should be balanced against the increased cost of this regimen for the treatment of these common infections, where often no antibiotic may be indicated at all...
  21. pmc Evidence on interventions to reduce medical errors: an overview and recommendations for future research
    J P Ioannidis
    Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
    J Gen Intern Med 16:325-34. 2001
    ..Evidence on reduction of medical errors needs to be better categorized, replicated, and tested in study designs maximizing protection from bias. Emphasis should be placed on serious errors...
  22. ncbi request reprint Completeness of safety reporting in randomized trials: an evaluation of 7 medical areas
    J P Ioannidis
    Clinical Trials and Evidence-Based Medicine Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
    JAMA 285:437-43. 2001
    ..Current standards for safety reporting in randomized trials should be revised to address this inadequacy...
  23. ncbi request reprint Maternal obesity and risk of cesarean delivery: a meta-analysis
    S Y Chu
    Division of Reproductive Health, Centers for Disease Control and Prevention, Mailstop K23, 1600 Clifton Road, Atlanta, GA 30333, USA
    Obes Rev 8:385-94. 2007
    ..The meta-regression found no evidence that these estimates were affected by selected study characteristics. Our findings provide a quantitative estimate of the risk of cesarean delivery associated with high maternal body mass...