R B Freeman

Summary

Affiliation: Rhode Island Hospital
Country: USA

Publications

  1. ncbi request reprint Liver transplant waiting time does not correlate with waiting list mortality: implications for liver allocation policy
    R B Freeman
    Department of Surgery, Division of Transplantation, Tufts University School of Medicine New England Medical Center, Boston, MA 02111, USA
    Liver Transpl 6:543-52. 2000
  2. ncbi request reprint The new liver allocation system: moving toward evidence-based transplantation policy
    Richard B Freeman
    Department of Surgery, Tufts New England Medical Center Tufts University School of Medicine, Boston, MA, USA
    Liver Transpl 8:851-8. 2002
  3. ncbi request reprint Diagnosing hepatocellular carcinoma: a virtual reality
    Richard B Freeman
    Division of Transplantation, Tufts University School of Medicine, New England Medical Center, Boston, MA 02111, USA
    Liver Transpl 8:762-4. 2002
  4. ncbi request reprint Redrawing organ distribution boundaries: results of a computer-simulated analysis for liver transplantation
    Richard B Freeman
    Department of Surgery, Division of Transplantation, New England Medical Center Tufts University School of Medicine, Boston, MA 02111, USA
    Liver Transpl 8:659-66. 2002
  5. ncbi request reprint Measuring medical students' experience with surgical problems and procedures
    R B Freeman
    Department of Surgery, Box 40, Tufts University School of Medicine New England Medical Center, 750 Washington Street, 02111, Boston, MA, USA
    Am J Surg 181:341-6. 2001
  6. ncbi request reprint Preliminary results of a liver allocation plan using a continuous medical severity score that de-emphasizes waiting time
    R B Freeman
    New England Medical Center Tufts University School of Medicine, Division of Transplant Surgery, Box 40, 750 Washington St, Boston, MA 02111, USA
    Liver Transpl 7:173-8. 2001
  7. doi request reprint Liver and intestine transplantation in the United States, 1997-2006
    R B Freeman
    Tufts New England Medical Center, Division of Transplant Surgery, Boston, MA, USA
    Am J Transplant 8:958-76. 2008
  8. ncbi request reprint Waiting list removal rates among patients with chronic and malignant liver diseases
    R B Freeman
    Division of Transplantation, Department of Surgery, Tufts New England Medical Center, Boston, Massachusetts, USA
    Am J Transplant 6:1416-21. 2006
  9. ncbi request reprint Living-donor versus cadaveric liver transplantation for non-resectable small hepatocellular carcinoma and compensated cirrhosis: a decision analysis
    S J Cheng
    New England Medical Center, Tufts University School of Medicine, 750 Washington St, PO Box 302, Boston, MA 02111, USA
    Transplantation 72:861-8. 2001
  10. ncbi request reprint Excellent liver transplant survival rates under the MELD/PELD system
    R B Freeman
    Division of Transplant Surgery, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Transplant Proc 37:585-8. 2005

Collaborators

Detail Information

Publications56

  1. ncbi request reprint Liver transplant waiting time does not correlate with waiting list mortality: implications for liver allocation policy
    R B Freeman
    Department of Surgery, Division of Transplantation, Tufts University School of Medicine New England Medical Center, Boston, MA 02111, USA
    Liver Transpl 6:543-52. 2000
    ..Waiting time and center transplant rates should not influence liver allocation policy...
  2. ncbi request reprint The new liver allocation system: moving toward evidence-based transplantation policy
    Richard B Freeman
    Department of Surgery, Tufts New England Medical Center Tufts University School of Medicine, Boston, MA, USA
    Liver Transpl 8:851-8. 2002
    ..Application of such risk models provides an evidenced-based approach on which to base further refinements and improve the model...
  3. ncbi request reprint Diagnosing hepatocellular carcinoma: a virtual reality
    Richard B Freeman
    Division of Transplantation, Tufts University School of Medicine, New England Medical Center, Boston, MA 02111, USA
    Liver Transpl 8:762-4. 2002
  4. ncbi request reprint Redrawing organ distribution boundaries: results of a computer-simulated analysis for liver transplantation
    Richard B Freeman
    Department of Surgery, Division of Transplantation, New England Medical Center Tufts University School of Medicine, Boston, MA 02111, USA
    Liver Transpl 8:659-66. 2002
    ..Enlarging liver distribution units likely will result in significant shifts in organs across current OPO boundaries, which will have a significant impact on the activity of many transplant centers...
  5. ncbi request reprint Measuring medical students' experience with surgical problems and procedures
    R B Freeman
    Department of Surgery, Box 40, Tufts University School of Medicine New England Medical Center, 750 Washington Street, 02111, Boston, MA, USA
    Am J Surg 181:341-6. 2001
    ..Measuring medical students' experience on their surgical clerkship rotations to assess the adequacy of the breadth of exposure is essential for producing generalist clinicians...
  6. ncbi request reprint Preliminary results of a liver allocation plan using a continuous medical severity score that de-emphasizes waiting time
    R B Freeman
    New England Medical Center Tufts University School of Medicine, Division of Transplant Surgery, Box 40, 750 Washington St, Boston, MA 02111, USA
    Liver Transpl 7:173-8. 2001
    ..We conclude that a continuous medical urgency score system allocates donor livers much more fairly to those in medical need and reduces waiting list mortality without sacrificing efficacy...
  7. doi request reprint Liver and intestine transplantation in the United States, 1997-2006
    R B Freeman
    Tufts New England Medical Center, Division of Transplant Surgery, Boston, MA, USA
    Am J Transplant 8:958-76. 2008
    ..Survival rates have increased over time. Small children waiting for intestine grafts continue to have the highest waiting list mortality...
  8. ncbi request reprint Waiting list removal rates among patients with chronic and malignant liver diseases
    R B Freeman
    Division of Transplantation, Department of Surgery, Tufts New England Medical Center, Boston, Massachusetts, USA
    Am J Transplant 6:1416-21. 2006
    ..Liver transplant candidates with HCC may be prioritized using a risk score analogous to the MELD score...
  9. ncbi request reprint Living-donor versus cadaveric liver transplantation for non-resectable small hepatocellular carcinoma and compensated cirrhosis: a decision analysis
    S J Cheng
    New England Medical Center, Tufts University School of Medicine, 750 Washington St, PO Box 302, Boston, MA 02111, USA
    Transplantation 72:861-8. 2001
    ..CONCLUSIONS: Living-donor liver transplantation should confer a substantial survival advantage for patients with compensated cirrhosis and non-resectable early stage hepatocellular carcinoma...
  10. ncbi request reprint Excellent liver transplant survival rates under the MELD/PELD system
    R B Freeman
    Division of Transplant Surgery, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Transplant Proc 37:585-8. 2005
    ..Although recipients with MELD scores in the highest quartile have reduced survival compared with other quartiles, their 1-year survival rate is acceptable when their extreme risk of dying without a transplant is taken into consideration...
  11. doi request reprint Moving kidney allocation forward: the ASTS perspective
    R B Freeman
    Tufts Medical Center, Boston, MA, USA
    Am J Transplant 9:1501-6. 2009
    ..We offer alternative policy options to address some of the unmet needs and issues that were brought to light during this interesting process...
  12. doi request reprint Stimulus for organ donation: a survey of the American Society of Transplant Surgeons membership
    J R Rodrigue
    The Transplant Center and Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Am J Transplant 9:2172-6. 2009
    ..Overall, there is strong support within the ASTS membership for changes to NOTA that would permit the implementation and careful evaluation of indirect, government-regulated strategies to increase organ donation...
  13. doi request reprint The impact of variation in donation after cardiac death policies among donor hospitals: a regional analysis
    J Y Rhee
    Transplantation, Tufts Medical Center, Boston, MA, USA
    Am J Transplant 11:1719-26. 2011
    ..Our regional analysis highlights the high degree of variability of hospital DCD policies, which may contribute to misunderstanding and confusion among providers and patients that may influence acceptance of this mode of donation...
  14. ncbi request reprint Survival benefit: quality versus quantity and trade-offs in developing new renal allocation systems
    R B Freeman
    Division of Transplantation, Tufts New England Medical Center, Box 40750 Washington Street, Boston, MA, USA
    Am J Transplant 7:1043-6. 2007
  15. doi request reprint Transplantation risks and the real world: what does 'high risk' really mean?
    R B Freeman
    Division of Transplantation, Department of Surgery, Tufts Medical Center, Boston, MA, USA
    Am J Transplant 9:23-30. 2009
    ..These comparisons can be helpful for informing patients and guiding future policy development...
  16. pmc Valganciclovir results in improved oral absorption of ganciclovir in liver transplant recipients
    M D Pescovitz
    Transplantation Section, Department of Surgery, and Department of Microbiology Immunology, Indiana University, Indianapolis, Indiana 42602, USA
    Antimicrob Agents Chemother 44:2811-5. 2000
    ..Oral VGC delivers systemic GCV exposure equivalent to that of standard oral GCV (at 450 mg) or i.v. GCV (at 900 mg of VGC). VGC has promise for effective CMV prophylaxis or treatment with once-daily oral dosing in transplant recipients...
  17. ncbi request reprint MELD/PELD: one year later
    R B Freeman
    Department of Surgery, Division of Transplantation, New England Medical Center Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Transplant Proc 35:2425-7. 2003
    ..Although there are many areas for improvement, which will be addressed in future refinements, the new US liver allocation plan has provided a more objective, patient-specific system to better rank waiting liver transplant candidates...
  18. ncbi request reprint Fetal cells participate over time in the response to specific types of murine maternal hepatic injury
    K Khosrotehrani
    Division of Genetics, Department of Pediatrics, Tufts New England Medical Center, Boston, MA 02111, USA
    Hum Reprod 22:654-61. 2007
    ..Our objective was to determine whether fetal cells participate in the response to specific murine post-partum hepatic injuries...
  19. doi request reprint The 'indirect' effects of cytomegalovirus infection
    R B Freeman
    Division of Transplantation, Tufts Medical Center, Boston, MA, USA
    Am J Transplant 9:2453-8. 2009
    ..This review focuses on the immunosuppressive and inflammatory mechanisms that have been attributed to CMV and will relate them to some of the clinical sequellae that have been associated with the indirect effects of CMV infection...
  20. doi request reprint Characterization of the withdrawal phase in a porcine donation after the cardiac death model
    J Y Rhee
    Division of Transplantation, Department of Surgery, Tufts Medical Center, Boston, MA, USA
    Am J Transplant 11:1169-75. 2011
    ..Early histologic evidence suggests that there is severe hepatocyte and biliary cell disruption in our DCD model. Further research using this model may provide a deeper understanding of the pathophysiology of the DCD liver...
  21. ncbi request reprint Mortality risk, behavior, and pediatric liver allocation
    Richard B Freeman
    Liver Transpl 12:12-5. 2006
  22. ncbi request reprint Liver allocation: the intent-to-treat approach
    Richard B Freeman
    Department of Surgery, Division of Transplantation, Tufts New England Medical Center, Boston, MA 02111, USA
    Transpl Int 19:270-4. 2006
  23. ncbi request reprint Optimizing staging for hepatocellular carcinoma before liver transplantation: A retrospective analysis of the UNOS/OPTN database
    Richard B Freeman
    Division of Transplantation, Department of Surgery, Tufts New England Medical Center, Boston, MA 02111, USA
    Liver Transpl 12:1504-11. 2006
    ..In conclusion, current imaging requirements for RS prior to liver transplantation are unacceptably inaccurate. Future policy should require more accurate modalities or combinations of techniques...
  24. ncbi request reprint Transplantation for hepatocellular carcinoma: The Milan criteria and beyond
    Richard B Freeman
    Division of Transplant Surgery, Tufts New England Medical Center, Boston, MA 02111, USA
    Liver Transpl 12:S8-13. 2006
    ..5. Liver allocation for HCC candidates in the context of increasing HCC prevalence requires better and evidence-based prioritization policies...
  25. ncbi request reprint In pursuit of the ideal liver allocation model
    Richard B Freeman
    Liver Transpl 8:799-801. 2002
  26. ncbi request reprint Justice, administrative law, and the transplant clinician: the ethical and legislative basis of a national policy on donor liver allocation
    Neal R Barshes
    Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA
    J Contemp Health Law Policy 23:200-30. 2007
  27. ncbi request reprint Model for end-stage liver disease (MELD) for liver allocation: a 5-year score card
    Richard B Freeman
    Division of Transplantation, Tufts New England Medical Center, Boston, MA, USA
    Hepatology 47:1052-7. 2008
  28. ncbi request reprint Liver transplantation for hepatocellular carcinoma: racial disparities?
    Richard B Freeman
    Am J Gastroenterol 103:128-30. 2008
    ..The cause of these results, however, remains obscure with the need for a more in-depth confirmation of these findings readily apparent...
  29. ncbi request reprint Liver transplantation for hepatocellular cancer: the impact of the MELD allocation policy
    Russell H Wiesner
    William J von Liebig Transplant Center, Mayo Clinic, 200 First Street, SW, Rochester, Minnesota 55905, USA
    Gastroenterology 127:S261-7. 2004
    ..It is hoped that through continued data collection and assessment, a consensus can be reached to further optimize the use of deceased donors in HCC recipients...
  30. ncbi request reprint Predicting the probability of progression-free survival in patients with small hepatocellular carcinoma
    Steve J Cheng
    Department of Medicine, Division of Clinical Decision Making, New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Liver Transpl 8:323-8. 2002
    ..To ensure that these patients have a fair opportunity to receive a cadaveric organ, HCC-specific scores predicted by our model could be added to MELD scores of patients with HCC...
  31. ncbi request reprint Regional variations in peer reviewed liver allocation under the MELD system
    Hector Rodriguez-Luna
    Transplantation Medicine, Mayo Clinic Hospital, Phoenix, Arizona, USA
    Am J Transplant 5:2244-7. 2005
    ..9%, p<0.0001). Demographics did not differ among regions requesting non-REDs.Widespread regional variations exist in the handling of requests for non-REDs. These variations point to the need for reform to standard exception criteria...
  32. ncbi request reprint Improving liver allocation: MELD and PELD
    Richard B Freeman
    Tufts New England Medical Center, Boston, MA, USA
    Am J Transplant 4:114-31. 2004
    ..Children younger than 2 years, however, still have a considerably higher rate of death on the waiting list than adults. A limited definition of ECD livers suggests that they are used more frequently for patients with lower MELD scores...
  33. ncbi request reprint Mathematical models and behavior: assessing delta MELD for liver allocation
    Richard B Freeman
    Am J Transplant 4:1735-6. 2004
  34. ncbi request reprint Overview of the MELD/PELD system of liver allocation indications for liver transplantation in the MELD era: evidence-based patient selection
    Richard B Freeman
    Tufts New England Medical Center Tufts University School of Medicine, Boston, MA, USA
    Liver Transpl 10:S2-3. 2004
  35. ncbi request reprint MELD score as a predictor of pretransplant and posttransplant survival in OPTN/UNOS status 1 patients
    Walter K Kremers
    The William J von Liebig Transplant Center, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA
    Hepatology 39:764-9. 2004
    ..68). In conclusion, liver allocation within the Status 1 designation may need to be further stratified by diagnosis, and MELD score may be useful for prioritizing FHF-NA candidates...
  36. ncbi request reprint Expanded criteria donor grafts for deceased donor liver transplantation under the MELD system: a decision analysis
    Manish G Amin
    Division of Gastroenterology and Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Liver Transpl 10:1468-75. 2004
    ..At less advanced MELD scores, the survival benefit depends on the risk of PGF associated with the ECD organ...
  37. ncbi request reprint Results of the first year of the new liver allocation plan
    Richard B Freeman
    Tufts University School of Medicine, New England Medical Center, Division of Transplantation, Boston, MA 02111, USA
    Liver Transpl 10:7-15. 2004
    ....
  38. ncbi request reprint Mortality risk versus other endpoints: who should come first on the liver transplant waiting list?
    Richard B Freeman
    Liver Transpl 10:675-7. 2004
  39. ncbi request reprint Summary report of a national conference: Evolving concepts in liver allocation in the MELD and PELD era. December 8, 2003, Washington, DC, USA
    Kim M Olthoff
    Department of Surgery, Division of Transplantation, University of Pennsylvania, Philadelphia, PA, USA
    Liver Transpl 10:A6-22. 2004
    ..Recommendations for the transplant community, based on the analysis of the MELD data, were discussed and are presented in the summary document...
  40. ncbi request reprint Aerobic capacity is associated with 100-day outcome after hepatic transplantation
    Scott K Epstein
    Department of Medicine, New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
    Liver Transpl 10:418-24. 2004
    ..Identification of predictors of survival at the time of listing for transplantation might lead to better resource allocation...
  41. ncbi request reprint "Transplant tourism" in the United States?
    Richard B Freeman
    Division of Transplantation, Tufts New England Medical Center, Boston, MA 02111, USA
    Transplantation 84:1559-60. 2007
  42. doi request reprint Donor postextubation hypotension and age correlate with outcome after donation after cardiac death transplantation
    Karen J Ho
    Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Transplantation 85:1588-94. 2008
    ..We hypothesized that donor postextubation parameters, including duration and severity of hemodynamic instability or hypoxia might be a better predictor of subsequent graft function...
  43. ncbi request reprint Liver allocation for HCC: a moving target
    Richard B Freeman
    Liver Transpl 10:49-51. 2004
  44. ncbi request reprint The impact of the model for end-stage liver disease on recipient selection for adult living liver donation
    Richard B Freeman
    Division of Transplant Surgery, Tufts New England Medical Center, Boston, MA 02111, USA
    Liver Transpl 9:S54-9. 2003
  45. ncbi request reprint Impact of donor infections on outcome of orthotopic liver transplantation
    Michael Angelis
    Division of Transplantation, Tufts New England Medical Center, Boston, MA 02111, USA
    Liver Transpl 9:451-62. 2003
    ..These issues are critically important to maximize the use of donated organs but also minimize recipient morbidity and graft dysfunction...
  46. ncbi request reprint The survival benefit of liver transplantation
    Robert M Merion
    Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA
    Am J Transplant 5:307-13. 2005
    ..With 1 year post-transplant follow-up, patients at lower risk of pre-transplant death do not have a demonstrable survival benefit from liver transplant...
  47. ncbi request reprint Predicting the future?
    Richard B Freeman
    Liver Transpl 13:1503-5. 2007
  48. ncbi request reprint MELD and the quality of life
    Richard B Freeman
    Liver Transpl 11:134-6. 2005
  49. ncbi request reprint Optimizing the use of donated cadaver livers: analysis and policy development to increase the application of split-liver transplantation
    Jean C Emond
    Center for Liver Diseases and Transplantation, New York Presbyterian Hospital, New York, NY 10032, USA
    Liver Transpl 8:863-72. 2002
    ..This article details the data reviewed by the liver committee and their recommendations on policy development for the expanded application of split-liver transplantation...
  50. ncbi request reprint MELD: the holy grail of organ allocation?
    Richard B Freeman
    Division of Transplant Surgery, Tufts New England Medical Center, P O Box 40, 750 Washington Street, Boston, MA 02111, USA
    J Hepatol 42:16-20. 2005
  51. ncbi request reprint Risk factors associated with the development of skin cancer after liver transplantation
    Abigail B Mithoefer
    Division of Transplantation, New England Medical Center Tufts University School of Medicine, Boston, MA 02111, USA
    Liver Transpl 8:939-44. 2002
    ..Recipients with identified risk factors may be candidates for prophylactic treatment and should be followed more intensively after liver transplantation...
  52. ncbi request reprint Report of the Crystal City meeting to maximize the use of organs recovered from the cadaver donor
    Bruce R Rosengard
    Harvard Medical School, Massachusetts General Hospital, Boston 02114, USA
    Am J Transplant 2:701-11. 2002
  53. ncbi request reprint Predicted lifetimes for adult and pediatric split liver versus adult whole liver transplant recipients
    Robert M Merion
    Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA
    Am J Transplant 4:1792-7. 2004
    ....
  54. ncbi request reprint The model for end-stage liver disease comes of age
    Richard B Freeman
    Division of Transplant Surgery, Tufts New England Medical Center, Box 40, 750 Washington Street, Boston, MA 02111, USA
    Clin Liver Dis 11:249-63. 2007
    ....
  55. ncbi request reprint MELD and liver allocation: continuous quality improvement
    Richard B Freeman
    Hepatology 40:787-9. 2004
  56. ncbi request reprint Liver and intestine transplantation
    John P Roberts
    University of California San Francisco, San Francisco, CA, USA
    Am J Transplant 3:78-90. 2003