Ronald Cohen

Summary

Affiliation: Rhode Island Hospital
Country: USA

Publications

  1. pmc Sustained attention is associated with left ventricular ejection fraction in older adults with heart disease
    Beth A Jerskey
    Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA
    J Int Neuropsychol Soc 15:137-41. 2009
  2. pmc Plasma cytokine concentrations associated with HIV/hepatitis C coinfection are related to attention, executive and psychomotor functioning
    Ronald A Cohen
    Department of Psychiatry and Human Behavior, Brown University School of Medicine, Providence, RI, USA
    J Neuroimmunol 233:204-10. 2011
  3. ncbi request reprint Early life stress and adult emotional experience: an international perspective
    Ronald A Cohen
    Brown University, USA
    Int J Psychiatry Med 36:35-52. 2006
  4. ncbi request reprint Long-term citicoline (cytidine diphosphate choline) use in patients with vascular dementia: neuroimaging and neuropsychological outcomes
    Ronald A Cohen
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, R I, USA
    Cerebrovasc Dis 16:199-204. 2003
  5. pmc Vascular and cognitive functions associated with cardiovascular disease in the elderly
    Ronald A Cohen
    Department of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA
    J Clin Exp Neuropsychol 31:96-110. 2009
  6. pmc Effects of nadir CD4 count and duration of human immunodeficiency virus infection on brain volumes in the highly active antiretroviral therapy era
    Ronald A Cohen
    Department of Psychiatry and Human Behavior and the Brain Science Program, Brown University School of Medicine, Providence, RI 02903, USA
    J Neurovirol 16:25-32. 2010
  7. doi request reprint Relationship of plasma cytokines and clinical biomarkers to memory performance in HIV
    Stephen Correia
    Department of Psychiatry and Human Behavior, Alpert Medical School, Brown University, Providence, RI, USA
    J Neuroimmunol 265:117-23. 2013
  8. pmc Subcortical hyperintensities impact cognitive function among a select subset of healthy elderly
    Robert H Paul
    Brown Medical School, Centers for Behavioral and Preventive Medicine, Department of Psychiatry and Human Behavior, 1 Hoppin Street, Providence, RI 02903, USA
    Arch Clin Neuropsychol 20:697-704. 2005
  9. ncbi request reprint Neuroimaging correlates of dementia rating scale performance at baseline and 12-month follow-up among patients with vascular dementia
    Lawrence H Sweet
    Brown University Medical School, Miriam Hospital, Providence, RI 20903, USA
    J Geriatr Psychiatry Neurol 16:240-4. 2003
  10. ncbi request reprint Apathy correlates with cognitive function but not CD4 status in patients with human immunodeficiency virus
    Robert Paul
    Brown Medical School, Department of Psychiatry and Human Behavior, Center for AIDS Research and Centers for Behavioral and Preventive Medicine, 1 Hoppin Street, Providence, RI 02903, USA
    J Neuropsychiatry Clin Neurosci 17:114-8. 2005

Research Grants

Detail Information

Publications71

  1. pmc Sustained attention is associated with left ventricular ejection fraction in older adults with heart disease
    Beth A Jerskey
    Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA
    J Int Neuropsychol Soc 15:137-41. 2009
    ..Overall, the results provide support for the hypothesis that a change in cardiac pumping leads to decrements in some aspects of attention; however, inhibitory processes are relatively spared. (JINS, 2009, 15, 137-141.)...
  2. pmc Plasma cytokine concentrations associated with HIV/hepatitis C coinfection are related to attention, executive and psychomotor functioning
    Ronald A Cohen
    Department of Psychiatry and Human Behavior, Brown University School of Medicine, Providence, RI, USA
    J Neuroimmunol 233:204-10. 2011
    ..The current results suggest that a complex relationship likely exists among cytokines [how?] and that these relationships are mediated not only by HIV infection but also by antiretroviral treatment and other comorbid conditions...
  3. ncbi request reprint Early life stress and adult emotional experience: an international perspective
    Ronald A Cohen
    Brown University, USA
    Int J Psychiatry Med 36:35-52. 2006
    ..Associations between ELS and current emotional distress suggest that these events have functional relevance and deserve further investigation...
  4. ncbi request reprint Long-term citicoline (cytidine diphosphate choline) use in patients with vascular dementia: neuroimaging and neuropsychological outcomes
    Ronald A Cohen
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, R I, USA
    Cerebrovasc Dis 16:199-204. 2003
    ..This randomized, double-blind clinical trial was conducted to determine whether daily citicoline treatment improves neurocognitive and neuroimaging outcome over 12 months among patients diagnosed with vascular dementia (VaD)...
  5. pmc Vascular and cognitive functions associated with cardiovascular disease in the elderly
    Ronald A Cohen
    Department of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA
    J Clin Exp Neuropsychol 31:96-110. 2009
    ....
  6. pmc Effects of nadir CD4 count and duration of human immunodeficiency virus infection on brain volumes in the highly active antiretroviral therapy era
    Ronald A Cohen
    Department of Psychiatry and Human Behavior and the Brain Science Program, Brown University School of Medicine, Providence, RI 02903, USA
    J Neurovirol 16:25-32. 2010
    ..The pattern of HIV-associated brain loss may be changing from a subcortical to a cortical disease among patients who are largely asymptomatic on HAART...
  7. doi request reprint Relationship of plasma cytokines and clinical biomarkers to memory performance in HIV
    Stephen Correia
    Department of Psychiatry and Human Behavior, Alpert Medical School, Brown University, Providence, RI, USA
    J Neuroimmunol 265:117-23. 2013
    ..Memory performance was not significantly related to HIV disease markers. The results indicate the importance of systemic immune and inflammatory markers to neurocognitive function in chronic and stable HIV disease. ..
  8. pmc Subcortical hyperintensities impact cognitive function among a select subset of healthy elderly
    Robert H Paul
    Brown Medical School, Centers for Behavioral and Preventive Medicine, Department of Psychiatry and Human Behavior, 1 Hoppin Street, Providence, RI 02903, USA
    Arch Clin Neuropsychol 20:697-704. 2005
    ..Further, the findings suggest that cognitive aging is largely determined by factors other than SH for most older adults...
  9. ncbi request reprint Neuroimaging correlates of dementia rating scale performance at baseline and 12-month follow-up among patients with vascular dementia
    Lawrence H Sweet
    Brown University Medical School, Miriam Hospital, Providence, RI 20903, USA
    J Geriatr Psychiatry Neurol 16:240-4. 2003
    ..These findings indicate that although SH volume increases with disease progression, the relative impact of SH volume on cognitive status decreases among patients with advanced VaD...
  10. ncbi request reprint Apathy correlates with cognitive function but not CD4 status in patients with human immunodeficiency virus
    Robert Paul
    Brown Medical School, Department of Psychiatry and Human Behavior, Center for AIDS Research and Centers for Behavioral and Preventive Medicine, 1 Hoppin Street, Providence, RI 02903, USA
    J Neuropsychiatry Clin Neurosci 17:114-8. 2005
    ..As such, the increased prevalence of apathy among HIV-infected adults may reflect HIV-associated neurologic dysfunction...
  11. pmc Neuroimaging and cardiac correlates of cognitive function among patients with cardiac disease
    Robert H Paul
    Center for Behavioral Medicine, Department of Psychiatry and Human Behavior, Brown Medical School, Providence, R I 02903, USA
    Cerebrovasc Dis 20:129-33. 2005
    ....
  12. ncbi request reprint Vascular dementia: a diagnostic conundrum for the clinical neuropsychologist
    Robert Paul
    Brown Medical School, Providence, Rhode Island 02903, USA
    Appl Neuropsychol 10:129-36. 2003
    ..In this article we review these factors and offer suggestions for future research...
  13. ncbi request reprint The relationship between frontal gray matter volume and cognition varies across the healthy adult lifespan
    Molly E Zimmerman
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island, USA
    Am J Geriatr Psychiatry 14:823-33. 2006
    ..The goal of the current study is to examine the relationship between age-related changes in regional gray matter volumes and cognitive function in a large, cross-sectional sample of healthy adults across the lifespan...
  14. ncbi request reprint The neuropsychological profile of vascular cognitive impairment--no dementia: comparisons to patients at risk for cerebrovascular disease and vascular dementia
    Kelly Davis Garrett
    Department of Psychiatry and Human Behavior, Brown Medical School, USA
    Arch Clin Neuropsychol 19:745-57. 2004
    ..The current findings suggest that poor cognitive flexibility and verbal retrieval in the context of preserved function in other domains may characterize the prodromal stage of VaD...
  15. ncbi request reprint Impulsivity and verbal deficits associated with domestic violence
    Ronald A Cohen
    Department of Psychiatry and Human Behavior, Brown University School of Medicine, Providence, Rhode Island 02960, USA
    J Int Neuropsychol Soc 9:760-70. 2003
    ..Both verbal expressive deficits and behavioral impulsivity appear to be relevant variables in predisposing men to domestic violence...
  16. ncbi request reprint Executive dysfunction and apathy predict functional impairment in Alzheimer disease
    Patricia A Boyle
    Brown Medical School, Providence, RI, USA
    Am J Geriatr Psychiatry 11:214-21. 2003
    ..The purpose of this study was to examine the extent to which executive cognitive dysfunction and frontally-mediated behavioral disturbances are associated with functional impairment in patients with mild-to-moderate Alzheimer disease (AD)...
  17. pmc Cardiac rehabilitation improves cognitive performance in older adults with cardiovascular disease
    John Gunstad
    Brown Medical School, Brown University, Box G MH, Providence, RI 02912 G, USA
    J Cardiopulm Rehabil 25:173-6. 2005
  18. ncbi request reprint Patterns of cognitive performance in middle-aged and older adults: A cluster analytic examination
    John Gunstad
    Department of Psychiatry, Brown Medical School, Centers for Behavioral and Preventive Medicine, Providence, RI 02903, USA
    J Geriatr Psychiatry Neurol 19:59-64. 2006
    ..Findings generally support the frontal aging hypothesis and may provide important information about healthy cognitive aging...
  19. pmc Apathy is associated with volume of the nucleus accumbens in patients infected with HIV
    Robert H Paul
    Brown Medical School Department of Psychiatry and Human Behavior, Providence, RI 02903, USA
    J Neuropsychiatry Clin Neurosci 17:167-71. 2005
    ..By contrast, ratings of depression were unrelated to either apathy or nucleus accumbens volume. These findings provide preliminary evidence that apathy reflects direct involvement of the central nervous system in patients with HIV...
  20. ncbi request reprint Cognitive status of young and older cigarette smokers: data from the international brain database
    Robert H Paul
    Centers for Behavioral and Preventive Medicine, Department of Psychiatry, Brown Medical School, Providence, RI 02903, USA
    J Clin Neurosci 13:457-65. 2006
    ..Cigarette smoking is associated with isolated and subtle cognitive difficulties among very healthy individuals...
  21. ncbi request reprint Age-dependent change in executive function and gamma 40 Hz phase synchrony
    Robert H Paul
    Centers for Behavioral and Preventive Medicine, Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02903, USA
    J Integr Neurosci 4:63-76. 2005
    ....
  22. ncbi request reprint Progressive morphometric and cognitive changes in vascular dementia
    John Gunstad
    Department of Psychiatry and Human Behavior, Brown Medical School, Miriam Hospital, Coro West Third Floor, 1 Hoppin St, Providence RI 02903, USA
    Arch Clin Neuropsychol 20:229-41. 2005
    ..Further research is needed to determine whether this observed decline is attributable to differential lesion distribution or statistical artifact...
  23. pmc Evaluating elements of executive functioning as predictors of instrumental activities of daily living (IADLs)
    Angela L Jefferson
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI, USA
    Arch Clin Neuropsychol 21:311-20. 2006
    ..e., working memory, generation, inhibition, planning, and sequencing) to IADLs among an older adult cohort at risk for future cognitive and functional decline...
  24. ncbi request reprint The serial position effect in mild and moderately severe vascular dementia
    Robert H Paul
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island 20906, USA
    J Int Neuropsychol Soc 8:584-7. 2002
    ....
  25. ncbi request reprint Ratings of subjective mental fatigue relate to cognitive performance in patients with myasthenia gravis
    Robert H Paul
    Department of Psychiatry and Human Behavior, Brown Medical School, Miriam Hospital, Providence, RI, 02906, USA
    J Clin Neurosci 9:243-6. 2002
    ..The results indicate that cognitive impairments may be associated with perceived fatigue in MG...
  26. pmc Brain ventricular volume and cerebrospinal fluid biomarkers of Alzheimer's disease
    Brian R Ott
    Department of Neurology, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA
    J Alzheimers Dis 20:647-57. 2010
    ..The basis for the apparent effect of APOE epsilon4 genotype on the relationship of ventricular volume to Abeta and tau levels is unknown, but could involve altered CSF-blood-brain barrier function during the course of disease...
  27. ncbi request reprint Sensitivity of the dementia rating scale in vascular dementia: comparison between two sets of criteria to define cognitive impairment
    Robert H Paul
    Brown Medical School, Providence, RI 20903, USA
    Cerebrovasc Dis 15:116-20. 2003
    ..The Dementia Rating Scale (DRS) is a common measure of cognitive function, but its sensitivity to identify deficits across cognitive domains in vascular dementia (VaD) remains unclear...
  28. ncbi request reprint Clinical correlates of cognitive decline in vascular dementia
    Robert H Paul
    Brown Medical School, Providence, Rhode Island 20903, USA
    Cogn Behav Neurol 16:40-6. 2003
    ..To determine whether demographic data, dementia severity, functional status, whole brain volume (WBV), or subcortical hyperintensity volume (SH) predict subsequent cognitive decline in vascular dementia (VaD)...
  29. ncbi request reprint Relationships between cognition and structural neuroimaging findings in adults with human immunodeficiency virus type-1
    Robert Paul
    Department of Psychiatry and Human Behavior, Centers for Behavioral and Preventive Medicine, Brown Medical School, Miriam Hospital, One Hoppin Street, Providence, RI 02903, USA
    Neurosci Biobehav Rev 26:353-9. 2002
    ..Suggestions for study design and new research directions are provided...
  30. ncbi request reprint Imaging phonological similarity effects on verbal working memory
    Lawrence H Sweet
    Department of Psychiatry and Human Behavior, Brown University Medical School, Providence, RI 02906, United States
    Neuropsychologia 46:1114-23. 2008
    ..Similarity effects likely include suspension of attention to unrelated and distracting processes to improve concentration...
  31. pmc Carotid artery intima-media thickness and cognition in cardiovascular disease
    Andreana P Haley
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI, United States
    Int J Cardiol 121:148-54. 2007
    ....
  32. doi request reprint Cerebral cortical arteriolar angiopathy, vascular beta-amyloid, smooth muscle actin, Braak stage, and APOE genotype
    Edward G Stopa
    Department of Pathology, Brown University School of Medicine, Providence, RI 02903, USA
    Stroke 39:814-21. 2008
    ..We examined the associations among the vascular beta-amyloid levels, smooth muscle actin, wall thickness, and lumen diameter to achieve greater understanding of the arteriolar changes that accompany Alzheimer disease (AD)...
  33. ncbi request reprint The relationship of subcortical MRI hyperintensities and brain volume to cognitive function in vascular dementia
    Ronald A Cohen
    Department of Psychiatry, Brown Medical School, Providence, Rhode Island, USA
    J Int Neuropsychol Soc 8:743-52. 2002
    ..That WBV emerged as a stronger correlate of dementia raises further questions regarding the cerebral mechanisms that contribute to the development of VaD...
  34. ncbi request reprint Cognitive and motor impairments predict functional declines in patients with vascular dementia
    Patricia A Boyle
    Department of Psychiatry, Brown Medical School, Providence, RI 02912, USA
    Int J Geriatr Psychiatry 17:164-9. 2002
    ..Patients with VaD display diverse cognitive and motor deficits, however, and relationships between these impairments and independent living abilities remain unclear...
  35. ncbi request reprint Examining the effect of cerebral perfusion abnormality magnitude on cognitive performance in recently abstinent chronic cocaine abusers
    Jeffrey N Browndyke
    Department of Psychiatry and Human Behavior Brown Medical School, Providence, Rhode Island, USA
    J Neuroimaging 14:162-9. 2004
    ..While perfusion abnormalities have been shown to relate to cognitive deficits in this substance abuse population, the relationship between cognitive performance and the magnitude of perfusion abnormality has yet to be fully determined...
  36. ncbi request reprint FMRI correlates of the WAIS-III symbol search subtest
    Lawrence H Sweet
    Brown University Medical School, Box G BH, Providence, RI 02912, USA
    J Int Neuropsychol Soc 11:471-6. 2005
    ..Furthermore, slower SS performance was related to greater recruitment of left hemisphere regions associated with executive function in other studies...
  37. ncbi request reprint Verbal working memory and atherosclerosis in patients with cardiovascular disease: an fMRI study
    Andreana P Haley
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island, USA
    J Neuroimaging 17:227-33. 2007
    ..The purpose of this study was to examine the relationship between IMT and brain activity during a verbal working memory (VWM) task in patients with cardiovascular disease (CVD)...
  38. ncbi request reprint Computer-related anxiety: examining the impact of technology-specific affect on the performance of a computerized neuropsychological assessment measure
    Jeffrey N Browndyke
    Department of Psychiatry Human Behavior, Miriam Hospital, Brown Medical School, Providence, Rhode Island 02903, USA
    Appl Neuropsychol 9:210-8. 2002
    ..Key words: computers, anxiety, computer-based task performance, clinical neuropsychology, Category Test..
  39. pmc C-reactive protein, but not homocysteine, is related to cognitive dysfunction in older adults with cardiovascular disease
    John Gunstad
    Brown Medical School, Providence, Rhode Island, USA
    J Clin Neurosci 13:540-6. 2006
    ..Further study is needed to identify mechanisms by which inflammatory processes impact on cognitive function and to determine whether reducing circulating levels of inflammatory markers results in improved cognition...
  40. ncbi request reprint The global deterioration scale: relationships to neuropsychological performance and activities of daily living in patients with vascular dementia
    Robert H Paul
    Department of Psychiatry and Human Behavior, Brown University School of Medicine, Miriam Hospital, Providence, Rhode Island, USA
    J Geriatr Psychiatry Neurol 15:50-4. 2002
    ..Further, the GDS score accurately classified 87% of the patients with VaD. These findings provide support for the validity of the GDS in general staging of dementia severity of VaD...
  41. pmc Category and letter verbal fluency across the adult lifespan: relationship to EEG theta power
    Adam M Brickman
    Brown Medical School, Department of Psychiatry, Centers for Behavioral and Preventive Medicine, USA
    Arch Clin Neuropsychol 20:561-73. 2005
    ..The differential age-associated decline between category and letter fluency suggests separate neurobiological substrates underlying the two domains of performance, which is not related to theta activity...
  42. ncbi request reprint Early life stress and morphometry of the adult anterior cingulate cortex and caudate nuclei
    Ronald A Cohen
    Department of Psychiatry and Human Behavior, Brown University, Providence, Rhode Island, USA
    Biol Psychiatry 59:975-82. 2006
    ..We examine whether reported adverse ELS defined as stressful and/or traumatic adverse childhood events (ACEs) is associated with smaller limbic and basal ganglia volumes...
  43. ncbi request reprint Acute neuropsychological functioning following cardiosurgical interventions associated with the production of intraoperative cerebral microemboli
    Jeffrey N Browndyke
    Department of Psychiatry and Human Behavior, Brown Medical School, The Miriam Hospital, RI 02903, USA
    Clin Neuropsychol 16:463-71. 2002
    ..Intraoperative microemboli counts were not significantly associated with postsurgical neuropsychological functioning in either the CABG or VR group...
  44. ncbi request reprint The impact of apathy and depression on quality of life in patients infected with HIV
    David Tate
    Brown Medical School, Department of Psychiatry and Human Behavior, Brown Medical School, Department of Infectious Disease, Providence, Rhode Island, USA
    AIDS Patient Care STDS 17:115-20. 2003
    ..Clinicians should continue to focus on depression as an important neuropsychiatric symptom associated with HIV...
  45. ncbi request reprint Functional magnetic resonance imaging response to increased verbal working memory demands among patients with multiple sclerosis
    Lawrence H Sweet
    Brown University Medical School, Providence, Rhode Island 02912, USA
    Hum Brain Mapp 27:28-36. 2006
    ..These findings may help to explain why MS patient performance decreases as a function of effort on neuropsychological tests...
  46. pmc Endothelial function and white matter hyperintensities in older adults with cardiovascular disease
    Karin F Hoth
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02903, USA
    Stroke 38:308-12. 2007
    ..The aim of the present study was to examine the association between endothelial-dependent and endothelial-independent vasodilatation and white matter hyperintensity volume...
  47. ncbi request reprint Diffusion tensor imaging of the corpus callosum: a cross-sectional study across the lifespan
    Nicole C R McLaughlin
    Brown Medical School, Department of Psychiatry and Human Behavior, Providence, RI 02912, USA
    Int J Dev Neurosci 25:215-21. 2007
    ..These results define the microstructural development of the white matter across the lifespan. Future studies are required to examine the neurobehavioral correlates of these neuroimaging indices...
  48. ncbi request reprint Cross-cultural assessment of neuropsychological performance and electrical brain function measures: additional validation of an international brain database
    Robert H Paul
    Department of Psychology, Behavioral Neuroscience, University of Missouri, St Louis, Missouri 63121, USA
    Int J Neurosci 117:549-68. 2007
    ..These findings indicate a high degree of similarity in neurocognitive and electrophysiological function among individuals residing in developed Western cultures, consistent with a traitlike status and the high heritability of the EEG...
  49. ncbi request reprint Body mass index and neuropsychological function in healthy children and adolescents
    John Gunstad
    Department of Psychology, Kent State University, Kent, OH 44242, USA
    Appetite 50:246-51. 2008
    ..Further work is needed to clarify the inconsistent findings between adults and minors...
  50. ncbi request reprint Proton MRS and neuropsychological correlates in AIDS dementia complex: evidence of subcortical specificity
    Robert H Paul
    Department of Behavioral Neuroscience, University of Missouri, St Louis, St Louis, MO 63121, USA
    J Neuropsychiatry Clin Neurosci 19:283-92. 2007
    ..Prospective studies are needed to elucidate the evolution of these changes in the setting of antiretroviral therapy...
  51. pmc Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task
    Jeffrey N Browndyke
    Department of Psychiatry and Behavioral Sciences, Division of Medical Psychology, Duke University Medical Center, Durham, NC 27705, USA
    Brain Inj 22:481-9. 2008
    ..Event-related, functional magnetic resonance imaging (fMRI) data were acquired in healthy participants during purposefully malingered and normal recognition memory performances to evaluate the neural substrates of feigned memory impairment...
  52. doi request reprint Cardiac dysfunction and cognition in older adults with heart failure
    Karin F Hoth
    Division of Psychosocial Medicine, National Jewish Medical and Research Center, Denver, CO 80206, USA
    Cogn Behav Neurol 21:65-72. 2008
    ..To characterize cognition in patients with moderate to severe heart failure and examine the association between 2 measures of systemic perfusion (ie, ejection fraction and cardiac index) and cognition...
  53. ncbi request reprint Handedness and cognition across the healthy lifespan
    John Gunstad
    Department of Psychology, Kent State University, Kent, Ohio 44242, USA
    Int J Neurosci 117:477-85. 2007
    ..No interaction-among handedness, sex, and age were found. These findings indicate cognitive differences associated with handedness exist independent of medical and psychiatric confounds. Further work is needed to clarify these findings...
  54. ncbi request reprint Functional magnetic resonance imaging of working memory among multiple sclerosis patients
    Lawrence H Sweet
    Medical College of Wisconsin, USA
    J Neuroimaging 14:150-7. 2004
    ..Functional magnetic resonance imaging (FMRI) studies have described a VWM system in healthy samples; however, functional neuroimaging of this system among MS patients is just beginning to appear...
  55. pmc Systemic hypoperfusion is associated with executive dysfunction in geriatric cardiac patients
    Angela L Jefferson
    Department of Neurology, Alzheimer s Disease Center, Boston University School of Medicine, Robinson Complex, Suite 7800, 715 Albany Street, Boston, MA 02118 2526, USA
    Neurobiol Aging 28:477-83. 2007
    ..The executive dysfunction profile may be secondary to reduced blood flow to vulnerable subcortical structures implicated in frontal-subcortical circuitry...
  56. ncbi request reprint Age effects in time estimation: relationship to frontal brain morphometry
    John Gunstad
    Department of Psychology, Kent Hall, Kent State University, Kent, OH 44242, USA
    J Integr Neurosci 5:75-87. 2006
    ..These results indicate that healthy aging is associated with altered time estimation and suggest that changes in frontal brain regions mediate these effects...
  57. ncbi request reprint Regional white matter and neuropsychological functioning across the adult lifespan
    Adam M Brickman
    Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA
    Biol Psychiatry 60:444-53. 2006
    ..The current study utilized magnetic resonance imaging (MRI) to more fully elucidate the relationship among age, regional white matter, and neuropsychological functioning...
  58. ncbi request reprint Behavioral problems as predictors of functional abilities of vascular dementia patients
    Tricia M Zawacki
    Department of Psychology, Georgia State University, Atlanta, Georgia 30303, USA
    J Neuropsychiatry Clin Neurosci 14:296-302. 2002
    ..These findings highlight the importance of apathy as an independent factor associated with functional independence beyond general cognitive abilities...
  59. ncbi request reprint Executive impairments predict functional declines in vascular dementia
    Patricia A Boyle
    Department of Neurology, Boston University School of Medicine, Alzheimer s Disease Center, Boston, MA, USA
    Clin Neuropsychol 18:75-82. 2004
    ..These findings demonstrate that baseline executive dysfunction is a significant and powerful predictor of future functional decline in individuals with VaD...
  60. ncbi request reprint Dissociation of the component processes of attention in healthy adults
    John Gunstad
    Kent State University, Department of Psychology, Kent Hall, Kent, OH 44242, USA
    Arch Clin Neuropsychol 21:645-50. 2006
    ..Future studies including both neuropsychological testing and functional neuroimaging may provide important insight into the underpinnings of attentional processes...
  61. pmc Relation of brain natriuretic peptide levels to cognitive dysfunction in adults > 55 years of age with cardiovascular disease
    John Gunstad
    Department of Psychology, Kent State University, Kent, Ohio, USA
    Am J Cardiol 98:538-40. 2006
    ..002), a measure of verbal and nonverbal abstraction abilities. In conclusion, the results of the present study provide the first evidence for an independent relation between BNP and cognitive dysfunction in older adults with CVD...
  62. pmc Cognitive predictors of functional decline in vascular dementia
    Angela L Jefferson
    Alzheimer s Disease Center, Department of Neurology, Boston University Medical Center, Boston, MA 02118, USA
    Int J Geriatr Psychiatry 21:752-4. 2006
    ..This study examined changes in cognitive-functional relationships in vascular dementia (VaD) over the course of one year...
  63. ncbi request reprint Computer-mediated measurement and subjective ratings of white matter hyperintensities in vascular dementia: relationships to neuropsychological performance
    Kelly Davis Garrett
    Neuropsychology Program, Drexel University, Philadelphia, PA, USA
    Clin Neuropsychol 18:50-62. 2004
    ..e., psychomotor speed, executive functioning) while the visual rating scale was not. Results suggest that this computer-mediated thresholding technique is superior to visual ratings of WMHs...
  64. ncbi request reprint Elevated body mass index is associated with executive dysfunction in otherwise healthy adults
    John Gunstad
    Department of Psychology, Kent Hall, Kent State University, Kent, OH 44242, USA
    Compr Psychiatry 48:57-61. 2007
    ..Further research is needed to identify the etiology of these deficits and whether they resolve after weight loss...
  65. pmc Blood pressure variability and white matter hyperintensities in older adults with cardiovascular disease
    John Gunstad
    Kent State University, Kent, Ohio
    Blood Press 14:353-8. 2005
    ..Additional studies are needed to examine the role of autoregulatory systems in the development of WMH, particularly those using beat-to-beat measures of BP...
  66. ncbi request reprint Preserved cognitive functioning over time in asymptomatic HIV-infected people in the MACS cohort
    Ronald A Cohen
    Neurology 69:2195-6. 2007
  67. pmc Lower cardiac output is associated with greater white matter hyperintensities in older adults with cardiovascular disease
    Angela L Jefferson
    Department of Neurology, Alzheimer s Disease Center, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    J Am Geriatr Soc 55:1044-8. 2007
    ..To preliminarily examine the association between cardiac output, a measure of systemic blood flow, and structural brain magnetic resonance imaging indices of white matter hyperintensities (WMHs)...
  68. ncbi request reprint Blood pressure variability and dementia rating scale performance in older adults with cardiovascular disease
    Therese Anne Keary
    Department of Psychology, Kent State University, Kent, OH, USA
    Cogn Behav Neurol 20:73-7. 2007
    ..The present study examined the relationship between multiple indices of blood pressure (BP) and cognitive function (as measured by the Dementia Rating Scale)...
  69. ncbi request reprint Exposure to early life trauma is associated with adult obesity
    John Gunstad
    Kent State University, Department of Psychology, Kent Hall, Kent OH 44242, USA
    Psychiatry Res 142:31-7. 2006
    ..These findings suggest that multiple processes mediate the relationship between early life stress and adult obesity and that their relative contributions may differ between men and women...
  70. ncbi request reprint BDNF Val66Met polymorphism is associated with body mass index in healthy adults
    John Gunstad
    Department of Psychology, Kent State University, Kent, Ohio, USA
    Neuropsychobiology 53:153-6. 2006
    ..These findings suggest a possible relationship between Val66Met polymorphism and BMI in healthy adults. Further work is needed to clarify possible mechanisms for this relationship...
  71. ncbi request reprint Hypertension and cerebral blood flow: implications for the development of vascular cognitive impairment in the elderly
    Ronald A Cohen
    Stroke 38:1715-7. 2007

Research Grants10

  1. Age Effects on HIV-associated Brain Dysfunction
    Ronald Cohen; Fiscal Year: 2009
    ..Clinical application of brain imaging methods, most notably in particular MRI diffusion tensor imaging, may occur, which may lead to advanced in diagnostics for HIV effects in the brain. ..
  2. Age Effects on HIV-associated Brain Dysfunction
    Ronald Cohen; Fiscal Year: 2007
    ..Clinical application of brain imaging methods, most notably in particular MRI diffusion tensor imaging, may occur, which may lead to advanced in diagnostics for HIV effects in the brain. ..
  3. HEART DISEASE, CNS DYSFUNCTION & OUTCOME IN THE ELDERLY
    Ronald Cohen; Fiscal Year: 2004
    ..We will also determine the effect of that such impairments have on CR outcome, quality of life, and longer-term health status of the elderly. ..
  4. Age Effects on HIV-associated Brain Dysfunction
    Ronald A Cohen; Fiscal Year: 2010
    ..Clinical application of brain imaging methods, most notably in particular MRI diffusion tensor imaging, may occur, which may lead to advanced in diagnostics for HIV effects in the brain. ..