Walter L Biffl

Summary

Affiliation: Rhode Island
Country: USA

Publications

  1. ncbi request reprint Implementation of a tertiary trauma survey decreases missed injuries
    Walter L Biffl
    Division of Trauma and Surgical Critical Care, Rhode Island Hospital Brown Medical School, 593 Eddy Street, APC 110, Providence, RI 02903, USA
    J Trauma 54:38-43; discussion 43-4. 2003
  2. ncbi request reprint Medical disasters: are we really prepared? An analysis of the station fire
    Walter L Biffl
    Division of Trauma and Surgical Critical Care, Rhode Island Hospital, Brown Medical School, Providence, RI, USA
    Med Health R I 86:342-3. 2003
  3. pmc Bologna Guidelines for Diagnosis and Management of Adhesive Small Bowel Obstruction (ASBO): 2010 Evidence-Based Guidelines of the World Society of Emergency Surgery
    Fausto Catena
    Emergency Surgery Unit, Department of General and Multivisceral Transplant Surgery, S, Orsola Malpighi University Hospital, Bologna, Italy
    World J Emerg Surg 6:5. 2011
  4. ncbi request reprint Diagnosis of blunt cerebrovascular injuries
    Walter L Biffl
    Division of Trauma and Surgical Critical Care, Rhode Island Hospital, and Brown Medical School, Providence, Rhode Island, USA
    Curr Opin Crit Care 9:530-4. 2003
  5. ncbi request reprint Legal prosecution of alcohol-impaired drivers admitted to a level I trauma center in Rhode Island
    Walter L Biffl
    Department of Surgery, Rhode Island Hospital Brown Medical School, Providence, 02903, USA
    J Trauma 56:24-9. 2004
  6. doi request reprint Management of patients with anterior abdominal stab wounds: a Western Trauma Association multicenter trial
    Walter L Biffl
    Department of Surgery, Denver Health Medical Center University of Colorado Denver, Denver, Colorado 80204 4507, USA
    J Trauma 66:1294-301. 2009
  7. ncbi request reprint Noninvasive diagnosis of blunt cerebrovascular injuries: a preliminary report
    Walter L Biffl
    Department of Surgery, Rhode Island Hospital Brown University, Providence, USA
    J Trauma 53:850-6. 2002
  8. ncbi request reprint Nutrition support of the trauma patient
    Walter L Biffl
    Department of Surgery, Rhode Island Hospital, Brown Medical School, Providence, Rhode Island, USA
    Nutrition 18:960-5. 2002
  9. ncbi request reprint Sixteen-slice computed tomographic angiography is a reliable noninvasive screening test for clinically significant blunt cerebrovascular injuries
    Walter L Biffl
    Department of Surgery, Rhode Island Hospital Brown University, Providence, 02903, USA
    J Trauma 60:745-51; discussion 751-2. 2006
  10. doi request reprint Validating the Western Trauma Association algorithm for managing patients with anterior abdominal stab wounds: a Western Trauma Association multicenter trial
    Walter L Biffl
    Department of Surgery, Denver Health Medical Center University of Colorado, Denver, Colorado 80204 4507, USA
    J Trauma 71:1494-502. 2011

Detail Information

Publications78

  1. ncbi request reprint Implementation of a tertiary trauma survey decreases missed injuries
    Walter L Biffl
    Division of Trauma and Surgical Critical Care, Rhode Island Hospital Brown Medical School, 593 Eddy Street, APC 110, Providence, RI 02903, USA
    J Trauma 54:38-43; discussion 43-4. 2003
    ..We hypothesized that implementation of a routine tertiary trauma survey (TS) would reduce the incidence of MIs in a Level I trauma center...
  2. ncbi request reprint Medical disasters: are we really prepared? An analysis of the station fire
    Walter L Biffl
    Division of Trauma and Surgical Critical Care, Rhode Island Hospital, Brown Medical School, Providence, RI, USA
    Med Health R I 86:342-3. 2003
  3. pmc Bologna Guidelines for Diagnosis and Management of Adhesive Small Bowel Obstruction (ASBO): 2010 Evidence-Based Guidelines of the World Society of Emergency Surgery
    Fausto Catena
    Emergency Surgery Unit, Department of General and Multivisceral Transplant Surgery, S, Orsola Malpighi University Hospital, Bologna, Italy
    World J Emerg Surg 6:5. 2011
    ..abstract:..
  4. ncbi request reprint Diagnosis of blunt cerebrovascular injuries
    Walter L Biffl
    Division of Trauma and Surgical Critical Care, Rhode Island Hospital, and Brown Medical School, Providence, Rhode Island, USA
    Curr Opin Crit Care 9:530-4. 2003
    ..The optimal criteria for screening, and the best diagnostic test, remain a matter of controversy. This review analyzes the available literature to propose management guidelines for the diagnosis of BCVI...
  5. ncbi request reprint Legal prosecution of alcohol-impaired drivers admitted to a level I trauma center in Rhode Island
    Walter L Biffl
    Department of Surgery, Rhode Island Hospital Brown Medical School, Providence, 02903, USA
    J Trauma 56:24-9. 2004
    ..The purpose of this study was to measure the rate of legal prosecution among impaired drivers admitted to a trauma center after MVCs, and to determine the recidivism rate among these individuals...
  6. doi request reprint Management of patients with anterior abdominal stab wounds: a Western Trauma Association multicenter trial
    Walter L Biffl
    Department of Surgery, Denver Health Medical Center University of Colorado Denver, Denver, Colorado 80204 4507, USA
    J Trauma 66:1294-301. 2009
    ....
  7. ncbi request reprint Noninvasive diagnosis of blunt cerebrovascular injuries: a preliminary report
    Walter L Biffl
    Department of Surgery, Rhode Island Hospital Brown University, Providence, USA
    J Trauma 53:850-6. 2002
    ..We hypothesized that CTA or MRA could reliably identify BCVI, obviating the need for arteriography. The purpose of this study was to determine the accuracy of CTA and MRA in identifying BCVI in asymptomatic patients...
  8. ncbi request reprint Nutrition support of the trauma patient
    Walter L Biffl
    Department of Surgery, Rhode Island Hospital, Brown Medical School, Providence, Rhode Island, USA
    Nutrition 18:960-5. 2002
    ..Nutrition support may prevent this sequence. This review addresses the need for early nutrition support, the preferred route of substrate delivery, and the potential advantages of "immune-enhancing" diets...
  9. ncbi request reprint Sixteen-slice computed tomographic angiography is a reliable noninvasive screening test for clinically significant blunt cerebrovascular injuries
    Walter L Biffl
    Department of Surgery, Rhode Island Hospital Brown University, Providence, 02903, USA
    J Trauma 60:745-51; discussion 751-2. 2006
    ..We implemented a liberal screening protocol for BCVI, employing 16-slice CTA. We hypothesized that CTA would detect all clinically significant BCVI...
  10. doi request reprint Validating the Western Trauma Association algorithm for managing patients with anterior abdominal stab wounds: a Western Trauma Association multicenter trial
    Walter L Biffl
    Department of Surgery, Denver Health Medical Center University of Colorado, Denver, Colorado 80204 4507, USA
    J Trauma 71:1494-502. 2011
    ..The purpose of this study was to evaluate the safety and efficacy of the algorithm in providing timely interventions for significant injuries...
  11. doi request reprint Early death and late morbidity after blood transfusion of injured children: a pilot study
    Fredric M Pieracci
    Department of Surgery, Denver Health Medical Center, Denver, CO 80206, USA
    J Pediatr Surg 47:1587-91. 2012
    ..The adverse immunomodulatory effects of blood transfusion are implicated in subsequent morbidity. We hypothesized that injured children requiring pRBC transfusion demonstrate patterns in outcome similar to those observed in adults...
  12. doi request reprint Blunt cerebrovascular injuries in the child
    Teresa S Jones
    Department of Surgery, Denver Health Medical Center, Denver, CO, USA
    Am J Surg 204:7-10. 2012
    ..The purpose of this study was to describe the incidence, injury patterns, and stroke rates of pediatric patients sustaining BCVIs...
  13. ncbi request reprint Effect of blood products transfusion on the development of postinjury multiple organ failure
    Jeffrey L Johnson
    Department of Surgery, University of Colorado Denver, USA
    Arch Surg 145:973-7. 2010
    ..Transfusion of fresh frozen plasma (FFP) and platelets is independently associated with the development of multiple organ failure (MOF) in critically injured patients...
  14. doi request reprint Primary fibrinolysis is integral in the pathogenesis of the acute coagulopathy of trauma
    Jeffry L Kashuk
    Division of Trauma, Acute Care, and Critical Care Surgery, Department of Surgery, Penn State Hershey Medical Center, College of Medicine, Hershey, PA 17033, USA
    Ann Surg 252:434-42; discussion 443-4. 2010
    ..We hypothesized that postinjury PF occurs early in severe shock, leading to postinjury coagulopathy, and ultimately hemorrhage-related death...
  15. ncbi request reprint Local wound exploration remains a valuable triage tool for the evaluation of anterior abdominal stab wounds
    C Clay Cothren
    Department of Surgery, Denver Health Medical Center, University of Colorado School of Medicine, 777 Bannock St, MC 0206, Denver, CO 80204, USA
    Am J Surg 198:223-6. 2009
    ..In patients without immediate indications for laparotomy, we hypothesized that LWE/DPL would identify patients requiring surgery while limiting unnecessary hospital admissions...
  16. ncbi request reprint Postinjury coagulopathy management: goal directed resuscitation via POC thrombelastography
    Jeffry L Kashuk
    Department of Surgery, Denver Health Medical Center, University of Colorado Denver, CO, USA
    Ann Surg 251:604-14. 2010
    ....
  17. ncbi request reprint Cervical spine fracture patterns predictive of blunt vertebral artery injury
    C Clay Cothren
    Department of Surgery, Denver Health Medical Center and University of Colorado Health Sciences Center, 777 Bannock Street, Denver, CO 80204, USA
    J Trauma 55:811-3. 2003
    ..Because of the proximity of the cervical spine and vertebral arteries, we queried whether all patients with cervical spine fractures required arteriography to rule out VAI...
  18. ncbi request reprint Anticoagulation is the gold standard therapy for blunt carotid injuries to reduce stroke rate
    C Clay Cothren
    Department of Surgery, Denver Health Medical Center and the University of Colorado Health Sciences Center, 80204, USA
    Arch Surg 139:540-5; discussion 545-6. 2004
    ..Aggressive screening, early angiographic diagnosis, and prompt anticoagulation for blunt carotid artery injuries (CAIs) improves neurologic outcome...
  19. ncbi request reprint The evolution of trauma care at a level I trauma center
    Walter L Biffl
    Division of Trauma and Surgical Critical Care, Rhode Island Hospital and Brown Medical School, Providence, RI 02903, USA
    J Am Coll Surg 200:922-9. 2005
    ....
  20. pmc Hypercoagulability following blunt solid abdominal organ injury: when to initiate anticoagulation
    Brandon C Chapman
    Department of Surgery, Denver Health Medical Center, University of Colorado Health Sciences Center, 777 Bannock Street MC0206, Denver, CO 80206, USA
    Am J Surg 206:917-22; discussion 922-3. 2013
    ..The optimal time to initiate venous thromboembolism pharmacoprophylaxis after blunt abdominal solid organ injury is unknown...
  21. doi request reprint Initial experiences with point-of-care rapid thrombelastography for management of life-threatening postinjury coagulopathy
    Jeffry L Kashuk
    Department of Surgery and Anesthesia, Denver Health Medical Center, Denver, Colorado, USA
    Transfusion 52:23-33. 2012
    ..We designed a prospective study to test the hypothesis that integrating TEG into our MTP would facilitate goal-directed therapy and provide equivalent outcomes compared to conventional coagulation testing...
  22. doi request reprint Diagnostic peritoneal lavage remains a valuable adjunct to modern imaging techniques
    John Y Cha
    Department of Surgery, University of South Florida College, Tampa, Florida, USA
    J Trauma 67:330-4; discussion 334-6. 2009
    ..We hypothesized that, while its indications may have changed, DPL remains essential in the rapid, effective triage of the trauma patient...
  23. doi request reprint Refractory postinjury thrombocytopenia is associated with multiple organ failure and adverse outcomes
    Trevor L Nydam
    Department of Surgery, University of Colorado Health Science Center and School of Medicine, Aurora, Colorado 80045, USA
    J Trauma 70:401-6; discussion 406-7. 2011
    ..In addition, recent studies suggest that platelets play a critical role in postinjury hyperinflammation. Therefore, we hypothesized that postinjury thrombocytopenia is a marker for progression to MOF...
  24. doi request reprint Rapid thrombelastography (r-TEG) identifies hypercoagulability and predicts thromboembolic events in surgical patients
    Jeffry L Kashuk
    Department of Surgery, Denver Health Medical Center, Denver, CO 80204, USA
    Surgery 146:764-72; discussion 772-4. 2009
    ..We hypothesized that r-TEG can be used as a screening tool to identify hypercoagulable states in surgical patients and would predict subsequent thromboembolic events...
  25. ncbi request reprint Lessons learned from a nightclub fire: institutional disaster preparedness
    Eric J Mahoney
    Department of Surgery, Division of Trauma and Surgical Critical Care, Rhode Island Hospital Brown Medical School, Providence, Rhode Island 02903, USA
    J Trauma 58:487-91. 2005
    ..In this report, we describe the events, the surgical response at our trauma center, and the lessons learned in institutional disaster preparedness...
  26. ncbi request reprint Isolated brain injury as a cause of hypotension in the blunt trauma patient
    Eric J Mahoney
    Department of Surgery, Rhode Island Hospital Brown Medical School, Providence, 02903, USA
    J Trauma 55:1065-9. 2003
    ..Emerging evidence suggests that, contrary to standard teaching, isolated brain injury may be associated with hypotension. This study sought to determine the frequency of isolated brain injury-induced hypotension in blunt trauma victims...
  27. doi request reprint Progressive postinjury thrombocytosis is associated with thromboembolic complications
    Jeffry L Kashuk
    Department of Surgery, Division of Trauma, Acute Care, and Acute Care Surgery, Penn State Hershey Medical Center and College of Medicine, Hershey, PA 17033 0850, USA
    Surgery 148:667-74; discussion 674-5. 2010
    ..We hypothesized that progressive postinjury thrombocytosis contributes to a hypercoagulable state that is associated with thrombelastography...
  28. ncbi request reprint Beneficial versus detrimental effects of neutrophils are determined by the nature of the insult
    Mario Perl
    Shock Trauma Research Laboratories, Division of Surgical Research, Department of Surgery, Rhode Island Hospital and Brown University, School of Medicine, Providence, RI 02903, USA
    J Am Coll Surg 204:840-52; discussion 852-3. 2007
    ....
  29. doi request reprint One thousand bedside percutaneous tracheostomies in the surgical intensive care unit: time to change the gold standard
    Lucy Z Kornblith
    Department of Surgery, Denver Health Medical Center and theUniversity of Colorado, Denver, CO, USA
    J Am Coll Surg 212:163-70. 2011
    ..Because this has been our preferred technique in the surgical ICU for more than 20 years, we reviewed our experience to ascertain its safety. We hypothesize that BPT has acceptably minimal morbidity, even in high-risk patients...
  30. ncbi request reprint Selective clinical management of anterior abdominal stab wounds
    Vassiliki Tsikitis
    Division of Trauma and Surgical Critical Care, Rhode Island Hospital Brown Medical School, 593 Eddy Street, APC 443, Providence, RI 02903, USA
    Am J Surg 188:807-12. 2004
    ..We implemented a protocol of serial clinical assessments to determine the need for laparotomy. The purpose of this study was to determine whether the approach is safe and effective...
  31. doi request reprint Treatment for blunt cerebrovascular injuries: equivalence of anticoagulation and antiplatelet agents
    C Clay Cothren
    Department of Surgery, Denver Health Medical Center, Denver, CO 80204, USA
    Arch Surg 144:685-90. 2009
    ..We hypothesize that the 2 antithrombotic treatment regimens, systemic heparin sodium vs antiplatelet agents, are equivalent for the treatment of blunt cerebrovascular injuries (BCVIs) to prevent devastating injury-related strokes...
  32. ncbi request reprint Lung-sparing techniques are associated with improved outcome compared with anatomic resection for severe lung injuries
    Clay Cothren
    Department of Surgery, Denver Health Medical Center, University of Colorado Health Sciences Center, 80204, USA
    J Trauma 53:483-7. 2002
    ..The purpose of this study was to compare the morbidity and mortality associated with nonanatomic and anatomic lung resection in the management of severe pulmonary injuries...
  33. pmc Transfer times to definitive care facilities are too long: a consequence of an immature trauma system
    David T Harrington
    Rhode Island Hospital Brown Medical, School Department of Surgery, Providence, Rhode Island 02903, USA
    Ann Surg 241:961-6; discussion 966-8. 2005
    ..The purpose of this study was to review our experience with interfacility transfers to identify problems that could be addressed in the development of a statewide trauma system...
  34. doi request reprint A negative urinalysis rules out catheter-associated urinary tract infection in trauma patients in the intensive care unit
    Robert T Stovall
    Department of Surgery, Denver Health Medical Center and the University of Colorado School of Medicine, Denver, CO 80206, USA
    J Am Coll Surg 217:162-6. 2013
    ..Whether the urinalysis (UA) is an adequate test for a urinary source of fever in the ICU trauma patient has not been demonstrated. We hypothesized that the UA is a valuable screen for UTI in the febrile, critically ill trauma patient...
  35. doi request reprint Acute appendicitis: a disease severity score for the acute care surgeon
    Geoffrey C Garst
    Department of Surgery, Denver Health Medical Center, University of Colorado Denver, Denver, Colorado, USA
    J Trauma Acute Care Surg 74:32-6. 2013
    ..Analogous to organ injury scales developed for trauma, a scoring system is needed for acute care surgery. The purpose of this study was to develop a disease severity score (DSS) for acute appendicitis, the most common surgical emergency...
  36. pmc Effect of damage control surgery on major abdominal vascular trauma
    Talia A Sorrentino
    University of Colorado Denver, Denver, Colorado, USA
    J Surg Res 177:320-5. 2012
    ..Damage control surgery was subsequently introduced to address this "lethal triad." The purpose of the present study was to evaluate the outcomes from our most recent 6-year experience compared with a cohort from 30 years ago...
  37. doi request reprint Pediatric blunt vertebral artery injury: case report and treatment plan
    Louis Seitz Brunworth
    Department of Surgery, Denver Health Medical Center and the University of Colorado Denver School of Medicine, Denver, CO, USA
    J Pediatr Surg 44:e5-9. 2009
    ..With few reports in the literature of blunt cerebrovascular injuries in the pediatric population, a review of the appropriate screening parameters, treatment plans, and follow-up is helpful for the practicing physician...
  38. ncbi request reprint Radiographic characteristics of postinjury splenic autotransplantation: avoiding a diagnostic dilemma
    C Clay Cothren
    Department of Surgery, Denver Health Medical Center and the University of Colorado Health Sciences Center, Denver, Colorado, USA
    J Trauma 57:537-41. 2004
    ..The purpose of this study was to determine whether there is a characteristic radiographic appearance of splenic implants, whether this appearance changes with time, and whether implants can be differentiated from abdominal abscesses...
  39. ncbi request reprint Postinjury life threatening coagulopathy: is 1:1 fresh frozen plasma:packed red blood cells the answer?
    Jeffry L Kashuk
    Department of Surgery and Surgical Research, Denver Health Medical Center, Denver, Colorado 80204 4507, USA
    J Trauma 65:261-70; discussion 270-1. 2008
    ..Consequently, we reviewed our massive transfusion practices during a 5-year period to test the hypothesis that 1:1 FFP:RBC within the first 6 hours reduces life threatening coagulopathy...
  40. ncbi request reprint Splenic artery embolization: Have we gone too far?
    Hadley E Smith
    Department of Surgery, Rhode Island Hospital and Brown Medical School, Providence, Rhode Island, USA
    J Trauma 61:541-4; discussion 545-6. 2006
    ..We perceived a higher rate of failure than that reported in the literature. The purpose of this study was to review our experience with splenic EMBO to identify predictors of failure of nonoperative/EMBO management...
  41. ncbi request reprint Endovascular stenting is rarely necessary for the management of blunt cerebrovascular injuries
    Clay Cothren Burlew
    Department of Surgery, Denver Health Medical Center and the University of Colorado School of Medicine, Denver, CO Electronic address
    J Am Coll Surg 218:1012-7. 2014
    ..The study purpose was to determine if antithrombotic therapy, rather than stenting, was effective in post-injury patients with high-grade vascular dissections and pseudoaneurysms...
  42. doi request reprint Blunt cerebrovascular trauma
    Clay Cothren Burlew
    Department of Surgery, Denver Health Medical Center, The University of Colorado Health Sciences Center, Denver, Colorado 80204, USA
    Curr Opin Crit Care 16:587-95. 2010
    ..Over the past decade, the recognition and subsequent management of these injuries has undergone a marked evolution. This review will focus on the rationale for BCVI screening, imaging options, and treatment modalities...
  43. doi request reprint Blunt cerebrovascular injuries: redefining screening criteria in the era of noninvasive diagnosis
    Clay Cothren Burlew
    Department of Surgery, Denver Health Medical Center and the University of Colorado School of Medicine, Denver, CO 80204, USA
    J Trauma Acute Care Surg 72:330-5; discussion 336-7, quiz 539. 2012
    ..The purpose of this study was to identify injury patterns of patients with BCVI that are not currently recommended screening criteria...
  44. ncbi request reprint The station nightclub fire
    David T Harrington
    Brown Medical School Rhode Island Hospital, Providence, Rhode Island 02903, USA
    J Burn Care Rehabil 26:141-3. 2005
  45. pmc Treatment-related outcomes from blunt cerebrovascular injuries: importance of routine follow-up arteriography
    Walter L Biffl
    Department of Surgery, Denver Health Medical Center, The University of Colorado Health Sciences Center, Denver, Colorado, USA
    Ann Surg 235:699-706; discussion 706-7. 2002
    ..To assess the impact of routine follow-up arteriography on the management and outcome of patients with acute blunt cerebrovascular injuries (BCVI)...
  46. ncbi request reprint Halo vest immobilization in the elderly: a death sentence?
    Sarah Majercik
    Division of Trauma and Surgical Critical Care, Rhode Island Hospital Brown Medical School, Providence, Rhode Island, USA
    J Trauma 59:350-6; discussion 356-8. 2005
    ..The purpose of this study was to compare the outcomes of elderly and younger CSF patients as related to treatment (HVI, surgery, or hard collar)...
  47. doi request reprint Western Trauma Association critical decisions in trauma: resuscitative thoracotomy
    Clay Cothren Burlew
    Department of Surgery, Denver Health Medical Center, Denver, CO, USA
    J Trauma Acute Care Surg 73:1359-63. 2012
    ..We have sought to formulate an evidence-based guideline for the current indications for RT after injury in the patient...
  48. doi request reprint One hundred percent fascial approximation can be achieved in the postinjury open abdomen with a sequential closure protocol
    Clay Cothren Burlew
    Department of Surgery, Denver Health Medical Center and the University of Colorado, Denver, Colorado, USA
    J Trauma Acute Care Surg 72:235-41. 2012
    ..We hypothesized that a sequential closure technique performed by a systematic protocol would achieve a higher rate of primary fascial closure than other described techniques...
  49. doi request reprint Defining the limits of resuscitative emergency department thoracotomy: a contemporary Western Trauma Association perspective
    Ernest E Moore
    Department of Surgery, Denver Health, Denver, Colorado 80204, USA
    J Trauma 70:334-9. 2011
    ..The purpose of this prospective multicenter study was to identify injury patterns and physiologic profiles at ED arrival that are compatible with survival...
  50. ncbi request reprint Validation of postinjury multiple organ failure scores
    Angela Sauaia
    Department of Medicine, Division of Health Care Policy and Research, University of Colorado, Denver, Colorado, USA
    Shock 31:438-47. 2009
    ..Basic concepts of each score can probably be combined to produce an improved MOF score...
  51. doi request reprint Risk factors for delirium after major trauma
    Erik M Angles
    Department of Surgery, University of Colorado at Denver, Health Sciences Center, 12631 East 17th Ave, Mail Stop C313, PO Box 6511, Aurora, CO, USA
    Am J Surg 196:864-9; discussion 869-70. 2008
    ..This study aimed to describe the natural history of delirium after major injury, to identify risk factors that predict the development of postinjury delirium, and to compare outcome measures in subjects with and without delirium...
  52. ncbi request reprint Pediatric trauma patients with isolated airway compromise or Glasgow Coma Scale less than 8: does immediate attending surgeon's presence upon arrival make a difference?
    Felix Lui
    Division of Pediatric Surgery, Brown Medical School and Hasbro Children s Hospital, Providence, RI 02905, USA
    J Pediatr Surg 40:103-6. 2005
    ..This report analyzes the outcome of children who met these isolated criteria and were treated before the change in guidelines was made...
  53. ncbi request reprint Transfusion of the injured patient: proceed with caution
    Christopher C Silliman
    Bonfils Blood Center, Denver Health Medical Center, Denver, Colorado 80230, USA
    Shock 21:291-9. 2004
    ..We further summarize studies with hemoglobin substitutes, whose use may obviate many of the untoward events of transfusion and promise to lead to better outcomes for injured patients...
  54. doi request reprint Patterns of early and late ventilator-associated pneumonia due to methicillin-resistant Staphylococcus aureus in a trauma population
    Jeffry L Kashuk
    Department of Surgery, Division of Acute Care Surgery, Penn State Hershey Medical Center and College of Medicine, Hershey, PA 17033, USA
    J Trauma 69:519-22. 2010
    ..We sought to determine the prevalence of early (≤4 days) and late (>4 days) MRSA pneumonia in ventilated multisystem trauma patients and to correlate findings with admission nasal swabs...
  55. doi request reprint Preperitoneal pelvic packing/external fixation with secondary angioembolization: optimal care for life-threatening hemorrhage from unstable pelvic fractures
    Clay Cothren Burlew
    Department of Surgery, Denver Health Medical Center and the University of Colorado Denver, Denver, CO 80204, USA
    J Am Coll Surg 212:628-35; discussion 635-7. 2011
    ..We hypothesized that PPP/EF arrests hemorrhage rapidly, facilitates emergent operative procedures, and ensures efficient use of angioembolization (AE)...
  56. ncbi request reprint Clinically relevant hypertonicity prevents stored blood- and lipid-mediated delayed neutrophil apoptosis independent of p38 MAPK or caspase-3 activation
    Walter L Biffl
    Department of Surgery, Rhode Island Hospital Brown Medical School, Providence, RI, USA
    Surgery 134:86-91. 2003
    ..We hypothesized that clinically relevant HTS would provoke PMN apoptosis, as well as prevent stored blood- and lipid-mediated delayed PMN apoptosis through activation of p38 mitogen-activated protein kinase (MAPK) and caspase-3...
  57. doi request reprint A cost-minimization analysis of phenytoin versus levetiracetam for early seizure pharmacoprophylaxis after traumatic brain injury
    Fredric M Pieracci
    Division of Trauma and Acute Care Surgery, Denver Health Medical Center, Denver, Colorado 80206, USA
    J Trauma Acute Care Surg 72:276-81. 2012
    ..The purpose of this study was to conduct a cost-minimization analysis, from the perspective of both the acute care institution (cost) and patient (charges), comparing these two strategies...
  58. ncbi request reprint Increased rate of infection associated with transfusion of old blood after severe injury
    Patrick J Offner
    Trauma Service, St Anthony Central Hospital, 4231 W 16th Ave, Denver, CO 80204, USA
    Arch Surg 137:711-6; discussion 716-7. 2002
    ..We hypothesized that transfusion of old blood increases infection risk in severely injured patients...
  59. ncbi request reprint "Leaning" the process of venous thromboembolism prophylaxis
    Walter L Biffl
    Denver Health Medical Center, Denver, USA
    Jt Comm J Qual Patient Saf 37:99-109. 2011
    ..VTE risk factors were not consistently assessed, and the prescribing of prophylaxis varied widely. Lean was employed to standardize and implement risk assessment and evidence-based VTE prophylaxis for the institution...
  60. ncbi request reprint The Outreach Trauma Program: a model for survival of the academic trauma center
    Walter L Biffl
    Department of Surgery, Denver Health Medical Center, and University of Colorado Health Sciences Center, Denver, Colorado, USA
    J Trauma 52:840-6. 2002
    ....
  61. ncbi request reprint Halo-vest immobilization increases early morbidity and mortality in elderly odontoid fractures
    Robert Z Tashjian
    Department of Surgery, Brown Medical School, Rhode Island Hospital, 2 Dudley Street, 170 Cooperative Care Building, Providence, RI 02905, USA
    J Trauma 60:199-203. 2006
    ..We review a series of odontoid fractures in elderly patients and evaluate for predictors for in-hospital morbidity and mortality...
  62. doi request reprint Surgeons provide definitive care to patients with gallstone pancreatitis
    Sarah E Judkins
    Department of Surgery, Denver Health Medical Center, The University of Colorado Denver School of Medicine, Denver, CO 80204, USA
    Am J Surg 202:673-7; discussion 677-8. 2011
    ..There are wide variations in the use of diagnostic testing and same-stay cholecystectomy. We hypothesize that a general surgery service (SURG) will deliver more efficient, definitive care for patients with GP...
  63. doi request reprint Mass-casualty incidents: how does an ICU prepare?
    Eric J Mahoney
    Division of Trauma and Surgical Critical Care, Department of Surgery, Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island 02903, USA
    J Intensive Care Med 23:219-35. 2008
    ....
  64. pmc Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis
    Mario Perl
    Shock Trauma Research Laboratories, Division of Surgical Research, Providence, RI 02903, USA
    Am J Pathol 167:1545-59. 2005
    ..These data indicate the pathophysiological significance of Fas activation in nonpulmonary/shock-induced ALI and the feasibility of intrapulmonary administration of anti-apoptotic siRNA in vivo...
  65. doi request reprint Noncitrated whole blood is optimal for evaluation of postinjury coagulopathy with point-of-care rapid thrombelastography
    Jeffry L Kashuk
    Department of Surgery, Denver Health Medical Center, University of Colorado at Denver, Denver, CO 80204, USA
    J Surg Res 156:133-8. 2009
    ..Additionally, we sought to compare the use of r-TEG with conventional coagulation tests in analysis of postinjury coagulopathy...
  66. doi request reprint Primary repair of civilian colon injuries is safe in the damage control scenario
    Jeffry L Kashuk
    Department of Surgery, Denver Health Medical Center, University of Colorado Denver and Health Sciences Center, Denver, CO 80204, USA
    Surgery 146:663-8; discussion 668-70. 2009
    ..We hypothesized that, even in the high-risk DL group, primary repair could be safely used after patient stabilization and that the open abdomen would facilitate the safety of this procedure...
  67. doi request reprint Imaging for blunt carotid and vertebral artery injuries
    Clay Cothren Burlew
    Surgical Intensive Care Unit, Department of Surgery, Denver Health Medical Center, University of Colorado School of Medicine, 777 Bannock Street, Denver, CO 80204, USA
    Surg Clin North Am 91:217-31. 2011
    ..BCVIs are rare, potentially devastating injuries; appropriate imaging in high-risk patients should be performed and prompt treatment initiated to prevent ischemic neurologic events...
  68. pmc Recombinant human activated protein C inhibits integrin-mediated neutrophil migration
    Gwendolyn F Elphick
    Department of Surgery, Rhode Island Hospital and Brown Medical School, Providence, RI, USA
    Blood 113:4078-85. 2009
    ..Thus, we conclude that leukocyte integrins are novel cellular receptors for rhAPC and the interaction decreases neutrophil recruitment into tissues, providing a potential mechanism by which rhAPC may protect against sepsis...
  69. doi request reprint Current concepts in resuscitation
    Fredric M Pieracci
    Department of Surgery, Denver Health Medical Center, University of Colorado School of Medicine, Denver, CO 80204, USA
    J Intensive Care Med 27:79-96. 2012
    ..This article reviews the diagnosis and differentiation of shock, measurements of tissue perfusion, current evidence regarding various resuscitative techniques, and complications of resuscitation...
  70. ncbi request reprint The station nightclub fire and disaster preparedness in Rhode Island
    Deborah Gutman
    Rhode Island Hospital, 593 Eddy Street, Providence, Rhode Island 02903, USA
    Med Health R I 86:344-6. 2003
  71. ncbi request reprint Predicting failure of outpatient laparoscopic cholecystectomy
    Thomas N Robinson
    Department of Surgery, Denver Health Medical Center University of Colorado Health Sciences Center, USA
    Am J Surg 184:515-8; discussion 518-9. 2002
    ..We hypothesized that patients in whom same day discharge (SDD) is unlikely may be identified preoperatively...
  72. ncbi request reprint Evaluation of a new technique for bedside percutaneous tracheostomy
    Clay Cothren
    Department of Surgery, Denver Health Medical Center, 777 Bannock, Denver, CO 80204, USA
    Am J Surg 183:280-2. 2002
    ..Recent modification of the technique to a single-step dilator prompted us to evaluate this in the critically injured patient...
  73. doi request reprint Decreased antibiotic utilization after implementation of a guideline for inpatient cellulitis and cutaneous abscess
    Timothy C Jenkins
    Department of Medicine, Denver Health Medical Center, Denver, CO 80204, USA
    Arch Intern Med 171:1072-9. 2011
    ..We hypothesized that implementation of an institutional guideline to standardize and streamline the evaluation and treatment of inpatient cellulitis and abscess would decrease antibiotic and health care resource utilization...
  74. ncbi request reprint Hyperosmolarity abrogates neutrophil cytotoxicity provoked by post-shock mesenteric lymph
    Ricardo J Gonzalez
    Denver Health Medical Center, Department of Surgery, Colorado 80204, USA
    Shock 18:29-32. 2002
    ..These studies suggest inhibition of PMN signal transduction is a mechanism whereby HTS resuscitation abrogates acute lung injury...
  75. doi request reprint Effect of educational debt on career and quality of life among academic surgeons
    Melina R Kibbe
    Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Ann Surg 249:342-8. 2009
    ..The purpose of this study was to assess indebtedness among academic surgeons and its repercussions on personal finances, quality of life, and career choices...
  76. doi request reprint Responsible development and application of surgical innovations: a position statement of the Society of University Surgeons
    Walter L Biffl
    Department of Surgery, Denver Health Medical Center University of Colorado Denver, Denver, CO, USA
    J Am Coll Surg 206:1204-9. 2008
  77. ncbi request reprint Secondary abdominal compartment syndrome: a potential threat for all trauma clinicians
    Zsolt Balogh
    Department of Trauma, Division of Surgery, John Hunter Hospital and University of Newcastle, Locked Bag 1, Hunter Region Mail Centre, Newcastle, NSW, Australia
    Injury 38:272-9. 2007
    ..With a reliable, predictive model and new monitoring techniques, trauma clinicians should be able to identify the high-risk patient and attenuate the impact of this syndrome...
  78. ncbi request reprint Extracranial vertebral artery dissection
    Walter L Biffl
    Med Health R I 86:292. 2003