Robert I Fox

Summary

Affiliation: Rheumatology Clinic
Country: USA

Publications

  1. ncbi request reprint Sjogren's syndrome: evolving therapies
    Robert I Fox
    Rheumatology Clinic, Scripps Memorial Hospital and Research Foundation, 9850 Genesee Ave, 910, La Jolla, CA 92037, USA
    Expert Opin Investig Drugs 12:247-54. 2003
  2. ncbi request reprint Sjögren's syndrome in dermatology
    Robert I Fox
    Rheumatology Clinic Scripps Memorial Hospital and Research Foundation, La Jolla, CA 92037, USA
    Clin Dermatol 24:393-413. 2006
  3. ncbi request reprint Current issues in the diagnosis and treatment of Sjögren's syndrome
    R I Fox
    Scripps Memorial Hospital, Allergy and Rheumatology Clinic, La Jolla, California 92037, USA
    Curr Opin Rheumatol 11:364-71. 1999
  4. ncbi request reprint Sjögren's syndrome
    Robert I Fox
    Rheumatology Clinic, Scripps Memorial Hospital and Research Foundation, La Jolla, CA 92037, USA
    Lancet 366:321-31. 2005
  5. ncbi request reprint Sjögren's syndrome: mechanisms of pathogenesis involve interaction of immune and neurosecretory systems
    Robert I Fox
    Allergy and Rheumatology Clinic, Scripps Memorial Hospital and Research Foundation, La Jolla, CA 92037, USA
    Scand J Rheumatol Suppl 116:3-13. 2002
  6. ncbi request reprint Use of muscarinic agonists in the treatment of Sjögren's syndrome
    R I Fox
    Allergy and Rheumatology Clinic, Scripps Memorial Hospital and Research Foundation, La Jolla, California 92037, USA
    Clin Immunol 101:249-63. 2001
  7. ncbi request reprint Approaches to the treatment of Sjögren's syndrome
    R I Fox
    Allergy and Rheumatology Clinic and the Division of Ophthalmology, Scripps Memorial Hospital, La Jolla, CA, USA
    J Rheumatol Suppl 61:15-21. 2000
  8. ncbi request reprint Sjögren's syndrome: current therapies remain inadequate for a common disease
    R I Fox
    Allergy and Rheumatology Clinic, Scripps Institute for Medical Research, 9850 Genesee Avenue, 860, La Jolla, CA 92037, USA
    Expert Opin Investig Drugs 9:2007-16. 2000
  9. ncbi request reprint Update in Sjögren syndrome
    R I Fox
    Allergy and Rheumatology Clinic, Scripps Memorial Hospital and Research Foundation, La Jolla, California 92037, USA
    Curr Opin Rheumatol 12:391-8. 2000
  10. ncbi request reprint Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge
    Mansun Law
    Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    Nat Med 14:25-7. 2008

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Sjogren's syndrome: evolving therapies
    Robert I Fox
    Rheumatology Clinic, Scripps Memorial Hospital and Research Foundation, 9850 Genesee Ave, 910, La Jolla, CA 92037, USA
    Expert Opin Investig Drugs 12:247-54. 2003
    ..However, the cost-effectiveness and safety of biological agents needs longer term follow up, as they appear much less dramatic in their effect on systemic lupus erythematosus or Sjogren's syndrome than in rheumatoid arthritis...
  2. ncbi request reprint Sjögren's syndrome in dermatology
    Robert I Fox
    Rheumatology Clinic Scripps Memorial Hospital and Research Foundation, La Jolla, CA 92037, USA
    Clin Dermatol 24:393-413. 2006
    ....
  3. ncbi request reprint Current issues in the diagnosis and treatment of Sjögren's syndrome
    R I Fox
    Scripps Memorial Hospital, Allergy and Rheumatology Clinic, La Jolla, California 92037, USA
    Curr Opin Rheumatol 11:364-71. 1999
    ..In pregnant patients who exhibit evidence of neonatal heart block, treatment with dexamethasone is preferred over prednisone, since the placenta is unable to metabolically activate the latter compound...
  4. ncbi request reprint Sjögren's syndrome
    Robert I Fox
    Rheumatology Clinic, Scripps Memorial Hospital and Research Foundation, La Jolla, CA 92037, USA
    Lancet 366:321-31. 2005
    ..The most difficult challenge in diagnosis and therapy is patients with symptoms of fibromyalgia (arthralgia, myalgia, fatigue) and oral and ocular dryness in the presence of circulating antinuclear antibodies...
  5. ncbi request reprint Sjögren's syndrome: mechanisms of pathogenesis involve interaction of immune and neurosecretory systems
    Robert I Fox
    Allergy and Rheumatology Clinic, Scripps Memorial Hospital and Research Foundation, La Jolla, CA 92037, USA
    Scand J Rheumatol Suppl 116:3-13. 2002
    ..The ability to modulate immune response and stimulate residual glandular elements provides new therapeutic opportunities for Sjögren's patients...
  6. ncbi request reprint Use of muscarinic agonists in the treatment of Sjögren's syndrome
    R I Fox
    Allergy and Rheumatology Clinic, Scripps Memorial Hospital and Research Foundation, La Jolla, California 92037, USA
    Clin Immunol 101:249-63. 2001
    ..Also, we review the structure and function of muscarinic receptors as they may relate to SS and the potential use of novel muscarinic agonists in SS...
  7. ncbi request reprint Approaches to the treatment of Sjögren's syndrome
    R I Fox
    Allergy and Rheumatology Clinic and the Division of Ophthalmology, Scripps Memorial Hospital, La Jolla, CA, USA
    J Rheumatol Suppl 61:15-21. 2000
    ..The recent development of muscarinic agonists, such as pilocarpine and cevimeline, serves an important step in recognizing the interaction between the immune and neuroendocrine systems...
  8. ncbi request reprint Sjögren's syndrome: current therapies remain inadequate for a common disease
    R I Fox
    Allergy and Rheumatology Clinic, Scripps Institute for Medical Research, 9850 Genesee Avenue, 860, La Jolla, CA 92037, USA
    Expert Opin Investig Drugs 9:2007-16. 2000
    ....
  9. ncbi request reprint Update in Sjögren syndrome
    R I Fox
    Allergy and Rheumatology Clinic, Scripps Memorial Hospital and Research Foundation, La Jolla, California 92037, USA
    Curr Opin Rheumatol 12:391-8. 2000
    ..In animal models, antagonists of tumor necrosis factor and inhibitors of de novo pyrimidine synthesis appear promising...
  10. ncbi request reprint Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge
    Mansun Law
    Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
    Nat Med 14:25-7. 2008
    ..The results provide evidence that broadly neutralizing antibodies to HCV protect against heterologous viral infection and suggest that a prophylactic vaccine against HCV may be achievable...
  11. ncbi request reprint Use of cevimeline, a muscarinic M1 and M3 agonist, in the treatment of Sjögren's syndrome
    Robert I Fox
    Allergy and Rheumatology Clinic, Scripps Memorial Hospital and Research Foundation, La Jolla, California, USA
    Adv Exp Med Biol 506:1107-16. 2002
  12. pmc Molecular analysis of the human autoantibody response to alpha-fodrin in Sjögren's syndrome reveals novel apoptosis-induced specificity
    Toshiaki Maruyama
    Department of Immunology, The Scripps Research Institute, La Jolla, California, USA
    Am J Pathol 165:53-61. 2004
    ..The anti-150-kd alpha-fodrin hmAbs may serve as valuable reagents for the study of SS pathogenesis and diagnostic analyses of SS salivary gland tissue...