Andrea Page-McCaw

Summary

Affiliation: Rensselaer Polytechnic Institute
Country: USA

Publications

  1. pmc An MMP liberates the Ninjurin A ectodomain to signal a loss of cell adhesion
    Shuning Zhang
    Department of Biology and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, USA
    Genes Dev 20:1899-910. 2006
  2. pmc Matrix metalloproteinases and the regulation of tissue remodelling
    Andrea Page-McCaw
    Department of Biology and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, USA
    Nat Rev Mol Cell Biol 8:221-33. 2007
  3. pmc Remodeling the model organism: matrix metalloproteinase functions in invertebrates
    Andrea Page-McCaw
    Center for Biotechnology and Interdisciplinary Studies and Department of Biology, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Semin Cell Dev Biol 19:14-23. 2008
  4. pmc Distinct functions for the catalytic and hemopexin domains of a Drosophila matrix metalloproteinase
    Bernadette M Glasheen
    Department of Biology and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Proc Natl Acad Sci U S A 106:2659-64. 2009
  5. pmc A matrix metalloproteinase mediates airway remodeling in Drosophila
    Bernadette M Glasheen
    Department of Biology and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Dev Biol 344:772-83. 2010

Research Grants

  1. Genetic and Functional Analysis of Drosophila Mmp 1
    Andrea Page McCaw; Fiscal Year: 2007
  2. Genetic and Functional Analysis of Drosophila Mmp 1
    Andrea Page McCaw; Fiscal Year: 2009

Collaborators

  • Zena Werb
  • Andrea Page McCaw
  • Bernadette M Glasheen
  • Shuning Zhang
  • RenĂ©e M Robbins
  • Greg J Beitel
  • Caitlin Piette
  • Aashish T Kabra
  • Elaine Kwan
  • Gyna E Sroga
  • Gina M Dailey

Detail Information

Publications5

  1. pmc An MMP liberates the Ninjurin A ectodomain to signal a loss of cell adhesion
    Shuning Zhang
    Department of Biology and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, USA
    Genes Dev 20:1899-910. 2006
    ..This liberated ectodomain promotes the loss of cell adhesion in a cell-nonautonomous manner. We suggest that tracheal cell adhesion is regulated by a novel mechanism utilizing an MMP and a ninjurin family member...
  2. pmc Matrix metalloproteinases and the regulation of tissue remodelling
    Andrea Page-McCaw
    Department of Biology and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, USA
    Nat Rev Mol Cell Biol 8:221-33. 2007
    ..Recent studies in mice and flies point to essential roles of MMPs as mediators of change and physical adaptation in tissues, whether developmentally regulated, environmentally induced or disease associated...
  3. pmc Remodeling the model organism: matrix metalloproteinase functions in invertebrates
    Andrea Page-McCaw
    Center for Biotechnology and Interdisciplinary Studies and Department of Biology, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Semin Cell Dev Biol 19:14-23. 2008
    ..In worms and in flies, MMPs are regulated by the JNK pathway...
  4. pmc Distinct functions for the catalytic and hemopexin domains of a Drosophila matrix metalloproteinase
    Bernadette M Glasheen
    Department of Biology and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Proc Natl Acad Sci U S A 106:2659-64. 2009
    ..Thus, we find that this MMP hemopexin domain has an apparent specialization for tissue invasion events, a finding with potential implications for inhibitor therapies...
  5. pmc A matrix metalloproteinase mediates airway remodeling in Drosophila
    Bernadette M Glasheen
    Department of Biology and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Dev Biol 344:772-83. 2010
    ....

Research Grants4

  1. Genetic and Functional Analysis of Drosophila Mmp 1
    Andrea Page McCaw; Fiscal Year: 2007
    ..We will identify the functions and mechanisms of an MMP in a simple model organism in the hopes of learning how to make better cancer drugs. ..
  2. Genetic and Functional Analysis of Drosophila Mmp 1
    Andrea Page McCaw; Fiscal Year: 2009
    ..We will identify the functions and mechanisms of an MMP in a simple model organism in the hopes of learning how to make better cancer drugs. ..