James F Winchester

Summary

Affiliation: RenalTech International
Country: USA

Publications

  1. ncbi request reprint The next step from high-flux dialysis: application of sorbent technology
    James F Winchester
    RenalTech International, New York, NY 10021, USA
    Blood Purif 20:81-6. 2002
  2. ncbi request reprint Beta-2 microglobulin in ESRD: an in-depth review
    James F Winchester
    RenalTech International, LLC, New York, NY 10021, USA
    Adv Ren Replace Ther 10:279-309. 2003
  3. ncbi request reprint Sorbents in acute renal failure and the systemic inflammatory response syndrome
    James F Winchester
    RenalTech International, New York, NY 10021, USA
    Blood Purif 21:79-84. 2003
  4. ncbi request reprint Removal of middle molecules with sorbents
    James F Winchester
    RenalTech International, LLC, 320 East 65th St, 116 New York, NY 10021, USA
    Artif Cells Blood Substit Immobil Biotechnol 30:547-54. 2002
  5. ncbi request reprint Special clinical problems in geriatric patients
    James F Winchester
    RenalTech International, New York, NY 10021, USA
    Semin Dial 15:116-20. 2002
  6. ncbi request reprint Dialysis and hemoperfusion in poisoning
    James F Winchester
    RenalTech International, SUNY Downstate Medical Center, 320 East 65th Street 116, New York, NY 10021, USA
    Adv Ren Replace Ther 9:26-30. 2002
  7. ncbi request reprint Sorbent hemoperfusion in end-stage renal disease: an in-depth review
    James F Winchester
    RenalTech International, SUNY Downstate Medical Center, 320 East 65th Street 116, New York, NY 10021, USA
    Adv Ren Replace Ther 9:19-25. 2002
  8. ncbi request reprint Sorbents in acute renal failure and end-stage renal disease: middle molecule and cytokine removal
    James F Winchester
    RenalTech International, New York, NY 10021, USA
    Blood Purif 22:73-7. 2004
  9. doi request reprint The impact of residual renal function on hospitalization and mortality in incident hemodialysis patients
    Zachary Z Brener
    Department of Medicine, Nephrology Division, Beth Israel Medical Center, New York, NY 10003, USA
    Blood Purif 31:243-51. 2011
  10. doi request reprint Metformin-induced lactic acidosis and acute pancreatitis precipitated by diuretic, celecoxib, and candesartan-associated acute kidney dysfunction
    Pat Audia
    Beth Israel Medical Center, Nephrology and Hypertension, New York, New York 10003, USA
    Clin Toxicol (Phila) 46:164-6. 2008

Collaborators

Detail Information

Publications32

  1. ncbi request reprint The next step from high-flux dialysis: application of sorbent technology
    James F Winchester
    RenalTech International, New York, NY 10021, USA
    Blood Purif 20:81-6. 2002
    ..Extensive clinical studies are underway to demonstrate the clinical utility and safety of adding routinely a sorbent hemoperfusion device to hemodialysis...
  2. ncbi request reprint Beta-2 microglobulin in ESRD: an in-depth review
    James F Winchester
    RenalTech International, LLC, New York, NY 10021, USA
    Adv Ren Replace Ther 10:279-309. 2003
    ..There seems to be a relative risk reduction in mortality when patients are treated with dialysis membranes that have a higher clearance of beta-2 microglobulin...
  3. ncbi request reprint Sorbents in acute renal failure and the systemic inflammatory response syndrome
    James F Winchester
    RenalTech International, New York, NY 10021, USA
    Blood Purif 21:79-84. 2003
    ....
  4. ncbi request reprint Removal of middle molecules with sorbents
    James F Winchester
    RenalTech International, LLC, 320 East 65th St, 116 New York, NY 10021, USA
    Artif Cells Blood Substit Immobil Biotechnol 30:547-54. 2002
  5. ncbi request reprint Special clinical problems in geriatric patients
    James F Winchester
    RenalTech International, New York, NY 10021, USA
    Semin Dial 15:116-20. 2002
    ..In the event of overwhelming illness and the patient's perception of the futility of continuation of dialysis, cessation of dialysis must be approached in a humane, considerate, and compassionate manner...
  6. ncbi request reprint Dialysis and hemoperfusion in poisoning
    James F Winchester
    RenalTech International, SUNY Downstate Medical Center, 320 East 65th Street 116, New York, NY 10021, USA
    Adv Ren Replace Ther 9:26-30. 2002
    ..Tables of drugs removed by both techniques are given for guidance. These tables will be updated regularly on the Advances in Renal Replacement Therapy website...
  7. ncbi request reprint Sorbent hemoperfusion in end-stage renal disease: an in-depth review
    James F Winchester
    RenalTech International, SUNY Downstate Medical Center, 320 East 65th Street 116, New York, NY 10021, USA
    Adv Ren Replace Ther 9:19-25. 2002
    ..Clinical application of hemoperfusion devices containing these sorbents is early in its development. Studies related to hemoperfusion in uremia are discussed in detail...
  8. ncbi request reprint Sorbents in acute renal failure and end-stage renal disease: middle molecule and cytokine removal
    James F Winchester
    RenalTech International, New York, NY 10021, USA
    Blood Purif 22:73-7. 2004
    ..Sorbent devices added to hemodialysis, or the use of such devices alone in inflammatory states, including sepsis, ARF, cardiopulmonary bypass, pre-explantation of donor organs and ESRD, are being studied...
  9. doi request reprint The impact of residual renal function on hospitalization and mortality in incident hemodialysis patients
    Zachary Z Brener
    Department of Medicine, Nephrology Division, Beth Israel Medical Center, New York, NY 10003, USA
    Blood Purif 31:243-51. 2011
    ..Few data are available on the impact of residual renal function (RRF) on mortality and hospitalization in hemodialysis (HD) patients. The objective of our study was to compare clinical outcomes for HD patients with and without RRF...
  10. doi request reprint Metformin-induced lactic acidosis and acute pancreatitis precipitated by diuretic, celecoxib, and candesartan-associated acute kidney dysfunction
    Pat Audia
    Beth Israel Medical Center, Nephrology and Hypertension, New York, New York 10003, USA
    Clin Toxicol (Phila) 46:164-6. 2008
    ..The kidney injury caused the accumulation of metformin, leading to lactic acidosis and acute pancreatitis. Sodium bicarbonate hemodialysis not only improved the metabolic abnormalities but also hastened the removal of metformin...
  11. doi request reprint Extracorporeal removal of toxins
    Pallavi K Tyagi
    Division of Nephrology and Hypertension, Department of Medicine, Beth Israel Medical Center, New York, New York, USA
    Kidney Int 74:1231-3. 2008
    ..TESS data do not separate continuous renal replacement therapy from hemodialysis, and not all poisonings were reported in this system. Nonetheless, these trends are useful to the nephrology community...
  12. doi request reprint Intoxications amenable to extracorporeal removal
    James F Winchester
    Division of Nephrology and Hypertension, Beth Israel Medical Center, New York, NY 10003, USA
    Adv Chronic Kidney Dis 18:167-71. 2011
    ..This article will discuss the principles of drug removal, the indications for dialysis, and give a brief outline of poisons amenable to dialysis...
  13. ncbi request reprint Guidelines for guidelines
    Richard Amerling
    Beth Israel Medical Center, 350 East 17th Street, New York, NY 10003, USA
    Blood Purif 25:36-8. 2007
    ..Little attention is paid to the potential for harm to patients, and to the profession of medicine, from the widespread use of guidelines...
  14. doi request reprint Continuous flow peritoneal dialysis: update 2012
    Richard Amerling
    Division of Nephrology and Hypertension, Beth Israel Medical Center, New York, NY 10003, USA
    Contrib Nephrol 178:205-15. 2012
    ..Potential applications include daily home dialysis, treatment of acute renal failure in the ICU, ultrafiltration of ascites, and the wearable artificial kidney...
  15. pmc Uric acid levels and all-cause and cardiovascular mortality in the hemodialysis population
    Walead Latif
    Beth Israel Medical Center, Albert Einstein College of Medicine, New York, New York, USA
    Clin J Am Soc Nephrol 6:2470-7. 2011
    ..Hyperuricemia is associated with hypertension, coronary artery disease, and chronic kidney disease. However, there are no specific data on the relationship of uric acid to cardiovascular disease in the chronic hemodialysis setting...
  16. ncbi request reprint Extracorporeal strategies for the removal of middle molecules
    James F Winchester
    Beth Israel Medical Center, New York, New York 10003, USA
    Semin Dial 19:110-4. 2006
    ..Factors influencing dialytic removal of LMWPs such as membrane characteristics, protein-membrane interactions, and solute removal mechanisms, as well as strategies to enhance clearance of these compounds are discussed...
  17. doi request reprint Guidelines have done more harm than good
    Richard Amerling
    Division of Nephrology and Hypertension, Beth Israel Medical Center, New York, NY 10003, USA
    Blood Purif 26:73-6. 2008
    ..This all but guarantees many guidelines are obsolete by the time they are published. Guidelines are produced with industry support and recommendations often have a major impact on sales of industry products...
  18. ncbi request reprint The 2006 K/DOQI guidelines for peritoneal dialysis adequacy are not adequate
    James F Winchester
    Division of Nephrology and Hypertension, Beth Israel Medical Center, 350 East 17th Street, New York, NY 10003, USA
    Blood Purif 25:103-5. 2007
    ..Body size has changed in the US and Canada over the last few decades and there are similar changes worldwide. We suggest that the minimum targets for peritoneal dialysis be reinstituted at the previous standard Kt/V(urea) of 2.0...
  19. ncbi request reprint The potential application of sorbents in peritoneal dialysis
    James F Winchester
    Beth Israel Medical Center, New York, NY 10003, USA
    Contrib Nephrol 150:336-43. 2006
    ..Sorbents assist the process of peritoneal dialysate regeneration and have the potential to improve the efficiency of continuous flow peritoneal dialysis...
  20. ncbi request reprint Three controversial issues in extracorporeal toxin removal
    Donald A Feinfeld
    Division of Nephrology and Hypertension, Beth Israel Medical Center, New York, New York 10003, USA
    Semin Dial 19:358-62. 2006
    ..In the meantime, we must continue to use less than ideal evidence and our own experience in dealing with these controversial issues to guide our decision-making process...
  21. pmc Acute non-occlusive mesenteric ischemia of the small bowel in a patient started on hemodialysis: a case report
    Zachary Z Brener
    Division of Nephrology, Beth Israel Medical Center, 1350 E, 17th Street, Baird Pav, 18th Floor, New York, NY, USA
    Cases J 1:217. 2008
    ..abstract:..
  22. doi request reprint Nephrolithiasis: evaluation and management
    Zachary Z Brener
    Nephrology Division, Department of Medicine, Beth Israel Medical Center, New York, NY 10003, USA
    South Med J 104:133-9. 2011
    ....
  23. ncbi request reprint A quick and simple estimate of creatinine clearance
    Farhan Ali
    Division of Nephrology and Hypertension, Beth Israel Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA
    J Nephrol 23:408-14. 2010
    ..However, these equations require complex calculations and several parameters. We derived an equation to estimate creatinine clearance (eCCr) rapidly...
  24. doi request reprint In-vitro myoglobin clearance by a novel sorbent system
    Viktoriya I Kuntsevich
    Department of Medicine, Division of Nephrology and Hypertension, Beth Israel Medical Center, New York, New York 10003, USA
    Artif Cells Blood Substit Immobil Biotechnol 37:45-7. 2009
    ..X-Sorb appears to be an effective sorbent for myoglobin and warrants a trial in vivo to determine whether it is equally effective and safe...
  25. doi request reprint Clinical benefit of preserving residual renal function in dialysis patients: an update for clinicians
    Zachary Z Brener
    Department of Medicine, Beth Israel Medical Center, 350 E Seventeenth Street, Eighteenth Floor, New York, NY 10003, USA
    Am J Med Sci 339:453-6. 2010
    ..This article will review the evidence supporting the importance of RRF on outcome and outline potential strategies that may better preserve RRF in patients on dialysis...
  26. ncbi request reprint Comments on the guideline debate
    Richard Amerling
    Division of Nephrology and Hypertension, Beth Israel Medical Center, New York, NY 10003, USA
    Clin J Am Soc Nephrol 2:208. 2007
  27. ncbi request reprint Absence of NF-kappaB activation by a new polystyrene-type adsorbent designed for hemoperfusion
    Elisa Menegatti
    Scuola di Specializzazione di Patologia Clinica, Universita di Torino, Torino, Italia
    Blood Purif 23:91-8. 2005
    ..Molecular structure and chemical modifications of the surface beads of this cartridge should prevent exposure of dense hydrophobic surface sites to proteins, and avoid the major drawbacks of previous polystyrene-type adsorbent materials...
  28. ncbi request reprint Middle molecules and small-molecular-weight proteins in ESRD: properties and strategies for their removal
    William R Clark
    NxStage Medical, Inc, Indiana University School of Medicine, Indianapolis, USA
    Adv Ren Replace Ther 10:270-8. 2003
    ....
  29. ncbi request reprint Novel changes in beta2-microglobulin in dialysis patients
    James F Winchester
    Clin Chem 51:1089-90. 2005
  30. ncbi request reprint Effect of a novel adsorbent on cytokine responsiveness to uremic plasma
    Marion D Morena
    Department of Medicine, Tupper Research Institute, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Kidney Int 63:1150-4. 2003
    ..We assessed the effect of this column on the bioreactivity of uremic plasma, as measured by cytokine responsiveness...
  31. ncbi request reprint Intradialytic blood volume monitoring in ambulatory hemodialysis patients: a randomized trial
    Donal N Reddan
    Duke University Medical Center, Box 3646, Durham, NC 27710, USA
    J Am Soc Nephrol 16:2162-9. 2005
    ..The atypically low hospitalization and mortality rates for the conventional monitoring group suggest that these findings should be generalized to the US hemodialysis population with caution...
  32. pmc Relationship between interdialytic weight gain and blood pressure among prevalent hemodialysis patients
    Jula K Inrig
    Department of Medicine, Duke University Medical Center, Durham, NC 27705, USA
    Am J Kidney Dis 50:108-18, 118.e1-4. 2007
    ..This study seeks to define the relationship between IDWG and BP in prevalent hemodialysis subjects...