Norm Harden

Summary

Affiliation: Rehabilitation Institute of Chicago
Country: USA

Publications

  1. doi request reprint Chronic pain and opiates: a call for moderation
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
    Arch Phys Med Rehabil 89:S72-6. 2008
  2. doi request reprint Complex regional pain syndrome: practical diagnostic and treatment guidelines, 4th edition
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Illinois 60611, USA
    Pain Med 14:180-229. 2013
  3. doi request reprint The osteoarthritis knee model: psychophysical characteristics and putative outcomes
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA
    J Pain 14:281-9. 2013
  4. pmc A preliminary fMRI study of analgesic treatment in chronic back pain and knee osteoarthritis
    Marwan N Baliki
    Department of Physiology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Ave, Chicago IL 60611, USA
    Mol Pain 4:47. 2008
  5. ncbi request reprint Prospective, randomized, single-blind, sham treatment-controlled study of the safety and efficacy of an electromagnetic field device for the treatment of chronic low back pain: a pilot study
    R N Harden
    Center for Pain Studies, Chicago, Illinois 60611, USA
    Pain Pract 7:248-55. 2007
  6. ncbi request reprint Proposed new diagnostic criteria for complex regional pain syndrome
    R Norman Harden
    Rehabilitation Institute of Chicago, Northwestern University, Chicago, Illinois, USA
    Pain Med 8:326-31. 2007
  7. ncbi request reprint Medication Quantification Scale Version III: update in medication classes and revised detriment weights by survey of American Pain Society Physicians
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA
    J Pain 6:364-71. 2005
  8. doi request reprint Residual limbs of amputees are significantly cooler than contralateral intact limbs
    R Norman Harden
    The Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA
    Pain Pract 8:342-7. 2008
  9. ncbi request reprint Biofeedback in the treatment of phantom limb pain: a time-series analysis
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago Northwestern University Medical School, Chicago, 446 Ontario Street, Suite 1011, Chicago, Illinois 60611, USA
    Appl Psychophysiol Biofeedback 30:83-93. 2005
  10. ncbi request reprint A critical analysis of the tender points in fibromyalgia
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Pain Med 8:147-56. 2007

Detail Information

Publications44

  1. doi request reprint Chronic pain and opiates: a call for moderation
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
    Arch Phys Med Rehabil 89:S72-6. 2008
    ..OVERALL ARTICLE OBJECTIVE: To present the case for thoughtful attention and moderation in prescribing opioids to treat chronic pain conditions...
  2. doi request reprint Complex regional pain syndrome: practical diagnostic and treatment guidelines, 4th edition
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Illinois 60611, USA
    Pain Med 14:180-229. 2013
    ..This is the fourth edition of diagnostic and treatment guidelines for complex regional pain syndrome (CRPS; aka reflex sympathetic dystrophy)...
  3. doi request reprint The osteoarthritis knee model: psychophysical characteristics and putative outcomes
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA
    J Pain 14:281-9. 2013
    ..Substantial intraindividual differences were found in KOA subjects and controls for mechanical wind-up and algometric thresholds...
  4. pmc A preliminary fMRI study of analgesic treatment in chronic back pain and knee osteoarthritis
    Marwan N Baliki
    Department of Physiology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Ave, Chicago IL 60611, USA
    Mol Pain 4:47. 2008
    ..Moreover, lidocaine patch treatment modulates distinct brain circuitry in each condition, yet in OA we observe divergent results with fMRI and with questionnaire based instruments...
  5. ncbi request reprint Prospective, randomized, single-blind, sham treatment-controlled study of the safety and efficacy of an electromagnetic field device for the treatment of chronic low back pain: a pilot study
    R N Harden
    Center for Pain Studies, Chicago, Illinois 60611, USA
    Pain Pract 7:248-55. 2007
    ..To evaluate the efficacy and safety of therapeutic electromagnetic fields (TEMF) on chronic low back pain. Secondary objectives included the investigation of the effects of TEMF on psychometric measures...
  6. ncbi request reprint Proposed new diagnostic criteria for complex regional pain syndrome
    R Norman Harden
    Rehabilitation Institute of Chicago, Northwestern University, Chicago, Illinois, USA
    Pain Med 8:326-31. 2007
    ..This update summarizes the latest international consensus group's action in Budapest, Hungary to approve and codify empirically validated, statistically derived revisions of the IASP criteria for CRPS...
  7. ncbi request reprint Medication Quantification Scale Version III: update in medication classes and revised detriment weights by survey of American Pain Society Physicians
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA
    J Pain 6:364-71. 2005
    ..4), whereas other classes previously given high weights (eg, "strong" opioids) received lower detriment ratings (from 5 to 3.4) in this survey. The MQS III must now be validated in clinical and research applications...
  8. doi request reprint Residual limbs of amputees are significantly cooler than contralateral intact limbs
    R Norman Harden
    The Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA
    Pain Pract 8:342-7. 2008
    ..To test the hypothesis that distal residual limbs (DRLs) have significant vasomotor abnormalities...
  9. ncbi request reprint Biofeedback in the treatment of phantom limb pain: a time-series analysis
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago Northwestern University Medical School, Chicago, 446 Ontario Street, Suite 1011, Chicago, Illinois 60611, USA
    Appl Psychophysiol Biofeedback 30:83-93. 2005
    ..Sensory descriptors of pain decreased more than the affective pain descriptors. These preliminary results provide some support for the use of biofeedback in the treatment of PLP and indicate the need for further, definitive study...
  10. ncbi request reprint A critical analysis of the tender points in fibromyalgia
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Pain Med 8:147-56. 2007
    ..To pilot methodologies designed to critically assess the American College of Rheumatology's (ACR) diagnostic criteria for fibromyalgia...
  11. pmc Validation of proposed diagnostic criteria (the "Budapest Criteria") for Complex Regional Pain Syndrome
    R Norman Harden
    Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
    Pain 150:268-74. 2010
    ..Overall, results corroborate the validity of the Budapest Criteria and suggest they improve upon existing IASP diagnostic criteria for CRPS...
  12. doi request reprint Negligible analgesic tolerance seen with extended release oxymorphone: a post hoc analysis of open-label longitudinal data
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA
    Pain Med 11:1198-208. 2010
    ..To examine the development of analgesic tolerance in patients on oxymorphone extended-release (OxymER)...
  13. doi request reprint Hypoesthesia in the distal residual limb of amputees
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, 446 E Ontario, Suite 1011, Chicago, IL 60611, USA
    PM R 2:607-11. 2010
    ..To test the emerging hypothesis that there is polymodal fiber degeneration/loss in distal residual limbs (DRL) of amputees...
  14. doi request reprint Development of a severity score for CRPS
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
    Pain 151:870-6. 2010
    ..Its utility as an outcome measure in research studies is also suggested, with potential statistical advantages over dichotomous diagnostic criteria...
  15. pmc Brain dynamics for perception of tactile allodynia (touch-induced pain) in postherpetic neuralgia
    P Y Geha
    Department of Physiology, Northwestern University, Feinberg School of Medicine, 5 120 Ward Building, 303 East Chicago Avenue, Chicago, IL 60611, USA
    Pain 138:641-56. 2008
    ..These results have important clinical implications regarding adequate therapy...
  16. ncbi request reprint Conducting clinical trials to establish drug efficacy in chronic pain
    R N Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Department of Physical Medicine and Rehabilitation, Northwestern University Medical School, Illinois 60610, USA
    Am J Phys Med Rehabil 80:547-57. 2001
    ..Involvement of a biostatistical consultant is recommended during all phases of clinical trials...
  17. doi request reprint Medication Quantification Scale Version III: internal validation of detriment weights using a chronic pain population
    Michael Gallizzi
    Center for Pain Studies, Rehabilitation Institute of Chicago, Northwestern University, Chicago, Illinois 60611, USA
    Pain Pract 8:1-4. 2008
    ..The MQS has been used as a unitary clinical and research outcome...
  18. ncbi request reprint The placebo effect in acute headache management: ketorolac, meperidine, and saline in the emergency department
    R N Harden
    Rehabilitation Institute of Chicago, IL 60611, USA
    Headache 36:352-6. 1996
    ..In addition, the use of a standard analgesic is necessary to demonstrate both assay sensitivity and magnitude of response to placebo...
  19. pmc Redirection of cutaneous sensation from the hand to the chest skin of human amputees with targeted reinnervation
    Todd A Kuiken
    Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Department of Physical Medicine and Rehabilitation, Northwestern University, 345 East Superior Street, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 104:20061-6. 2007
    ....
  20. ncbi request reprint Signs and symptoms of the myofascial pain syndrome: a national survey of pain management providers
    R N Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Illinois 60611, USA
    Clin J Pain 16:64-72. 2000
    ..The goal of this study was to assess clinical consensus regarding whether myofascial pain syndrome (MPS) is a legitimate and distinct diagnosis as well as the signs and symptoms characterizing MPS...
  21. pmc The brain in chronic CRPS pain: abnormal gray-white matter interactions in emotional and autonomic regions
    Paul Y Geha
    Department of Physiology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Neuron 60:570-81. 2008
    ..These abnormalities encompass emotional, autonomic, and pain perception regions, implying that they likely play a critical role in the global clinical picture of CRPS...
  22. ncbi request reprint Comparative measurement of pelvic floor pain sensitivity in chronic pelvic pain
    Frank F Tu
    Department of Obstetrics and Gynecology, Feinberg School of Medicine at Northwestern University, Chicago, Illinois, USA
    Obstet Gynecol 110:1244-8. 2007
    ..The present study was undertaken to estimate pelvic floor and vaginal pressure-pain detection thresholds both in women with pelvic pain and healthy women...
  23. doi request reprint Do omega-6 and trans fatty acids play a role in complex regional pain syndrome? A pilot study
    Christopher Ramsden
    Rehabilitation Institute of Chicago, Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Pain Med 11:1115-25. 2010
    ..The study aims to compare the omega-6 (n-6) and omega-3 (n-3) highly unsaturated fatty acids (HUFA), and trans fatty acid (trans FA) status of Complex Regional Pain Syndrome (CRPS) patients to pain-free controls...
  24. doi request reprint Botulinum toxin a in the treatment of chronic tension-type headache with cervical myofascial trigger points: a randomized, double-blind, placebo-controlled pilot study
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, 446 E Ontario, Chicago, IL 60611, USA
    Headache 49:732-43. 2009
    ..To evaluate the efficacy of botulinum toxin A (BT-A) as a prophylactic treatment for chronic tension-type headache (CTTH) with myofascial trigger points (MTPs) producing referred head pain...
  25. ncbi request reprint Chronic neuropathic pain. Mechanisms, diagnosis, and treatment
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA
    Neurologist 11:111-22. 2005
    ....
  26. ncbi request reprint Topiramate for phantom limb pain: a time-series analysis
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago Northwestern University Medical School, Chicago, Illinois 60611, USA
    Pain Med 6:375-8. 2005
    ..This analysis supports a hypothesis that topiramate may be effective in reducing phantom limb pain, and suggests a definitive study is indicated...
  27. ncbi request reprint Increased systemic catecholamines in complex regional pain syndrome and relationship to psychological factors: a pilot study
    R Norman Harden
    Rehabilitation Institute of Chicago, Center for Pain Studies, 446 E Ontario, Ste 1011, Chicago, IL 60611, USA
    Anesth Analg 99:1478-85; table of contents. 2004
    ..Definitive studies are needed to examine these hypotheses in detail...
  28. ncbi request reprint Diagnosis of complex regional pain syndrome: signs, symptoms, and new empirically derived diagnostic criteria
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, IL, USA
    Clin J Pain 22:415-9. 2006
    ..The review will also address issues of staging and subtyping the syndrome, as well as a discussion of the salient signs, symptoms, and tests appropriate for use in the diagnosis...
  29. ncbi request reprint A clinical approach to complex regional pain syndrome
    R N Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Illinois 60611, USA
    Clin J Pain 16:S26-32. 2000
    ..To allow the deficiencies in the science to paralyze the clinical process is therapeutic nihilism, and not acceptable...
  30. pmc Brain activity for spontaneous pain of postherpetic neuralgia and its modulation by lidocaine patch therapy
    P Y Geha
    Department of Physiology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Ave, Chicago, IL 60611, USA
    Pain 128:88-100. 2007
    ..The results show a specific brain activity pattern for PHN spontaneous pain, and implicate areas involved in emotions and reward as best reflecting changes in pain with treatment...
  31. ncbi request reprint Cognitive factors influence outcome following multidisciplinary chronic pain treatment: a replication and extension of a cross-lagged panel analysis
    J W Burns
    Finch University of Health Sciences, The Chicago Medical School, Psychology Department, Building 51, 3333 Green Bay Road, Chicago, IL 60064, USA
    Behav Res Ther 41:1163-82. 2003
    ..Findings replicate those of a recent report regarding cross-lagged effects, and offer support that cognitive changes may indeed influence late-treatment changes in outcomes...
  32. ncbi request reprint Prospective examination of pain-related and psychological predictors of CRPS-like phenomena following total knee arthroplasty: a preliminary study
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, 345 E Superior St, Chicago, IL 60610, USA
    Pain 106:393-400. 2003
    ..There appears to be a modest utility for preoperative distress and pain in predicting CRPS signs and symptoms following TKA, although false positive rates are relatively high...
  33. doi request reprint Examining the cross-cultural validity of the english short-form McGill Pain Questionnaire using the matched moderated regression methodology
    Jennifer L Zinke
    Northwestern University, Chicago, IL 60611, USA
    Clin J Pain 26:153-62. 2010
    ..The aims of this study were to examine the psychometric properties and the differential item functioning (DIF) of the short-form McGill Pain Questionnaire (SF-MPQ) to test the cultural differences in verbally based pain expression...
  34. ncbi request reprint Chronic pain patients are impaired on an emotional decision-making task
    A Vania Apkarian
    Department of Physiology, Northwestern University Medical School, 303 E Chicago Avenue, Chicago, IL 60611, USA
    Pain 108:129-36. 2004
    ..Our evidence indicates that chronic pain is associated with a specific cognitive deficit, which may impact everyday behavior especially in risky, emotionally laden, situations...
  35. ncbi request reprint Pharmacotherapy of complex regional pain syndrome
    R Norman Harden
    Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois, USA
    Am J Phys Med Rehabil 84:S17-28. 2005
    ..As with most chronic pain syndromes, pharmacotherapy coupled with functional restoration and an interdisciplinary approach to treatment are essential to a successful outcome...
  36. ncbi request reprint Chronic pain and the emotional brain: specific brain activity associated with spontaneous fluctuations of intensity of chronic back pain
    Marwan N Baliki
    Department of Physiology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Neurosci 26:12165-73. 2006
    ....
  37. ncbi request reprint Chronic back pain is associated with decreased prefrontal and thalamic gray matter density
    A Vania Apkarian
    Department of Physiology and Institute of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Neurosci 24:10410-5. 2004
    ..Our results imply that CBP is accompanied by brain atrophy and suggest that the pathophysiology of chronic pain includes thalamocortical processes...
  38. ncbi request reprint Treatment of complex regional pain syndrome: functional restoration
    R Norman Harden
    Center for Pain Studies, Chicago, IL 60610, USA
    Clin J Pain 22:420-4. 2006
    ..Medications, interventions, and psychotherapy will be covered in other sections of this series...
  39. ncbi request reprint Do changes in cognitive factors influence outcome following multidisciplinary treatment for chronic pain? A cross-lagged panel analysis
    John W Burns
    Department of Psychology, Finch University of Health Sciences Chicago Medical School, Illinois 60064, USA
    J Consult Clin Psychol 71:81-91. 2003
    ..Findings advance understanding of pain treatment process and suggest that negative cognition changes may indeed affect improvements in treatment outcome...
  40. ncbi request reprint Stages of change in readiness to adopt a self-management approach to chronic pain: the moderating role of early-treatment stage progression in predicting outcome
    John W Burns
    Department of Psychology, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Rd, North Chicago, IL 60064, USA
    Pain 115:322-31. 2005
    ..In contrast, late-treatment gains of patients initially taking a predominant precontemplation stance were unaffected by their degree of early-treatment attitude changes...
  41. ncbi request reprint Diagnostic and treatment issues in postamputation pain after landmine injury
    Philip Wiffen
    Oxford Pain Relief Unit, UK
    Pain Med 7:S209-12. 2006
  42. ncbi request reprint Current diagnosis and therapy of complex regional pain syndrome: refining diagnostic criteria and therapeutic options
    Allen W Burton
    University of Texas MD Anderson Cancer Center, Department of Anestiology and Pain Medicine, 1400 Holcombe Boulavard 409, Houston, TX 77030, USA
    Expert Rev Neurother 5:643-51. 2005
    ..Thus, in spite of our evolving understanding of this neurologic disorder, in many cases complex regional pain syndrome remains difficult to diagnose and treat successfully...
  43. ncbi request reprint Neurophysiology of pain from landmine injury
    Andre Muller
    Centre d Etude et Traitement de la Douleur, Hopital Civil, Strasbourg, France
    Pain Med 7:S204-8. 2006
  44. ncbi request reprint Complex regional pain syndrome: are there distinct subtypes and sequential stages of the syndrome?
    Stephen Bruehl
    Department of Anesthesiology, Vanderbilt University School of Medicine, Suite 403 G MAB, 1211 Twenty First Avenue South, Nashville, TN 37232 1557, USA
    Pain 95:119-24. 2002
    ..However, several distinct CRPS subtypes are suggested, and these could ultimately have utility in targeting treatment more effectively...