Jay L Mellies

Summary

Affiliation: Reed College
Country: USA

Publications

  1. pmc Zinc-induced envelope stress diminishes type III secretion in enteropathogenic Escherichia coli
    Jay L Mellies
    Biology Department, Reed College, Portland OR, USA
    BMC Microbiol 12:123. 2012
  2. pmc The global regulator Ler is necessary for enteropathogenic Escherichia coli colonization of Caenorhabditis elegans
    Jay L Mellies
    Biology Department, Reed College, 3203 S E Woodstock Blvd, Portland, OR 97202, USA
    Infect Immun 74:64-72. 2006
  3. pmc SOS regulation of the type III secretion system of enteropathogenic Escherichia coli
    Jay L Mellies
    Biology Department, Reed College, 3203 S E Woodstock Blvd, Portland, OR 97202, USA
    J Bacteriol 189:2863-72. 2007
  4. pmc Enteropathogenic and enterohemorrhagic Escherichia coli virulence gene regulation
    Jay L Mellies
    Biology Department, Reed College, 3203 S E Woodstock Boulevard, Portland, OR 97202, USA
    Infect Immun 75:4199-210. 2007
  5. pmc Ler interdomain linker is essential for anti-silencing activity in enteropathogenic Escherichia coli
    Jay L Mellies
    Biology Department, Reed College, Portland, OR 97202, USA
    Microbiology 154:3624-38. 2008
  6. pmc Interkingdom signaling between pathogenic bacteria and Caenorhabditis elegans
    Jay L Mellies
    Department of Biology, Reed College, Portland, OR 97202, USA
    Trends Microbiol 18:448-54. 2010
  7. pmc Ler of pathogenic Escherichia coli forms toroidal protein-DNA complexes
    Jay L Mellies
    Biology Department, Reed College, Portland, OR 97202, USA
    Microbiology 157:1123-33. 2011
  8. pmc Interaction of Ler at the LEE5 (tir) operon of enteropathogenic Escherichia coli
    Kenneth R Haack
    Biology Department, Reed College, Portland, Oregon 97202, USA
    Infect Immun 71:384-92. 2003

Research Grants

Collaborators

  • Kenneth R Haack
  • Christopher L Robinson
  • Jonathan W Fowlkes
  • Kristie J Miller

Detail Information

Publications8

  1. pmc Zinc-induced envelope stress diminishes type III secretion in enteropathogenic Escherichia coli
    Jay L Mellies
    Biology Department, Reed College, Portland OR, USA
    BMC Microbiol 12:123. 2012
    ....
  2. pmc The global regulator Ler is necessary for enteropathogenic Escherichia coli colonization of Caenorhabditis elegans
    Jay L Mellies
    Biology Department, Reed College, 3203 S E Woodstock Blvd, Portland, OR 97202, USA
    Infect Immun 74:64-72. 2006
    ....
  3. pmc SOS regulation of the type III secretion system of enteropathogenic Escherichia coli
    Jay L Mellies
    Biology Department, Reed College, 3203 S E Woodstock Blvd, Portland, OR 97202, USA
    J Bacteriol 189:2863-72. 2007
    ....
  4. pmc Enteropathogenic and enterohemorrhagic Escherichia coli virulence gene regulation
    Jay L Mellies
    Biology Department, Reed College, 3203 S E Woodstock Boulevard, Portland, OR 97202, USA
    Infect Immun 75:4199-210. 2007
  5. pmc Ler interdomain linker is essential for anti-silencing activity in enteropathogenic Escherichia coli
    Jay L Mellies
    Biology Department, Reed College, Portland, OR 97202, USA
    Microbiology 154:3624-38. 2008
    ..Conversely, replacing the H-NS linker region with that of Ler caused increased transcription at LEE5 in a strain deleted for hns. In summary, the interdomain linker specific to Ler is necessary for anti-silencing activity in EPEC...
  6. pmc Interkingdom signaling between pathogenic bacteria and Caenorhabditis elegans
    Jay L Mellies
    Department of Biology, Reed College, Portland, OR 97202, USA
    Trends Microbiol 18:448-54. 2010
    ..Several regulatory networks have been implicated in nematode innate immune function and are being exploited in the C. elegans infection model to develop novel chemical therapies against bacterial pathogens...
  7. pmc Ler of pathogenic Escherichia coli forms toroidal protein-DNA complexes
    Jay L Mellies
    Biology Department, Reed College, Portland, OR 97202, USA
    Microbiology 157:1123-33. 2011
    ..Lastly, we present electron microscopy images of toroidal Ler-DNA structures that are predicted to be involved in stimulating gene expression...
  8. pmc Interaction of Ler at the LEE5 (tir) operon of enteropathogenic Escherichia coli
    Kenneth R Haack
    Biology Department, Reed College, Portland, Oregon 97202, USA
    Infect Immun 71:384-92. 2003
    ..We describe a model in which Ler activates transcription at both divergent overlapping paired and single promoters by displacing H-NS, which results in the disruption of a repressing nucleoprotein complex...

Research Grants2

  1. Ler-Mediated Regulation of EPEC Virulence Genes
    JAY MELLIES; Fiscal Year: 2004
    ....