Changes in bone density and turnover after alendronate or estrogen withdrawalRichard D Wasnich
Radiant Research Honolulu, Honolulu, HI 96814, USA
Menopause 11:622-30. 2004
..To compare bone mineral density (BMD) and bone turnover changes after therapy withdrawal in postmenopausal women treated with alendronate or estrogen-progestin...
Oral daily ibandronate prevents bone loss in early postmenopausal women without osteoporosisMichael R McClung
Oregon Osteoporosis Center, Portland, Oregon 97213, USA
J Bone Miner Res 19:11-8. 2004
..1% and 1.8%, respectively; p < or = 0.0001 versus placebo) with 2.5 mg ibandronate after 24 months. Oral ibandronate is a promising option for the prevention of postmenopausal bone loss...
Prevention of postmenopausal bone loss: six-year results from the Early Postmenopausal Intervention Cohort StudyMichael R McClung
Oregon Osteoporosis Center, 5050 Northeast Hoyt, Suite 651, Portland, Oregon 97213, USA
J Clin Endocrinol Metab 89:4879-85. 2004
..5, 10.3, and 8.9% of women taking placebo, 2.5 mg alendronate, or 5 mg alendronate daily, respectively. Therapy with alendronate is an effective and promising strategy for the prevention of postmenopausal osteoporosis...
Ibandronate produces significant, similar antifracture efficacy in North American and European women: new clinical findings from BONECharles H Chesnut
Osteoporosis Research Group, University of Washington, Seattle, WA, USA
Curr Med Res Opin 21:391-401. 2005
..As osteoporosis medications must be effective across different populations, an additional objective of BONE was to investigate and report the effect of oral ibandronate in North American and European women, as described here...
Changes in bone density and turnover explain the reductions in incidence of nonvertebral fractures that occur during treatment with antiresorptive agentsMarc C Hochberg
University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
J Clin Endocrinol Metab 87:1586-92. 2002
..Antiresorptive agents that do not produce large increases in BMD or large reductions in BCM do not appear to and would not be expected to decrease the risk of nonvertebral fractures...
Relationship between phalangeal bone density and risk of vertebral fractureMisako Ohtsuka
Department of Gynecology and Obstetrics, Kyushu University Hospital, Fukouka, Japan
J Clin Densitom 5:11-5. 2002
..The phalangeal BMD measurements obtained with this device are not significantly influenced by the presence of osteoarthritis of the hands...
Letter to the editorMarc C Hochberg
Bone 35:1222-4; author reply 1225-6. 2004
How useful are measures of BMD and bone turnover?Paul D Miller
Colorado Center for Bone Research, Lakewood, CO, USA
Curr Med Res Opin 21:545-54. 2005
..Analyses that have suggested that change in BMD or bone turnover 'explains' little of change in fracture risk with treatment appear to be flawed. Although neither can perfectly predict fracture, they are our current best alternatives...