Meera Mahalingam

Summary

Affiliation: Quest Diagnostics
Country: USA

Publications

  1. ncbi Morphea-like tattoo reaction
    Meera Mahalingam
    Quest Diagnostics Incorporated, Cambridge, MA 02139, USA
    Am J Dermatopathol 24:392-5. 2002
  2. ncbi Atypical pilar leiomyoma: cutaneous counterpart of uterine symplastic leiomyoma?
    M Mahalingam
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine Boston, Massachusetts, USA
    Am J Dermatopathol 23:299-303. 2001
  3. ncbi Metastatic papillary carcinoma of the thyroid
    M Mahalingam
    Quest Diagnostics Incorporated, Cambridge, MA 02139, USA
    J Cutan Pathol 31:509-12. 2004
  4. ncbi Follicular acantholysis: a subtle clue to the early diagnosis of pemphigus vulgaris
    M Mahalingam
    Quest Diagnostics Incorporated, Cambridge, Massachusetts, USA
    Am J Dermatopathol 27:237-9. 2005
  5. doi Mixed versus pure variants of desmoplastic melanoma: a genetic and immunohistochemical appraisal
    Daniel D Miller
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
    Mod Pathol 25:505-15. 2012
  6. doi An immunohistochemical comparison of cytokeratin 7, cytokeratin 15, cytokeratin 19, CAM 5.2, carcinoembryonic antigen, and nestin in differentiating porocarcinoma from squamous cell carcinoma
    Meera Mahalingam
    Department of Dermatology, Dermatopathology Section, Boston University School of Medicine, Boston, MA 02118, USA
    Hum Pathol 43:1265-72. 2012
  7. doi Nestin-positive stem cells in neurofibromas from patients with neurofibromatosis type 1-tumorigenic or incidental?
    Marinya Pongpudpunth
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, MA 02118, USA
    Am J Dermatopathol 32:574-7. 2010
  8. doi Stem cell markers (cytokeratin 15, cytokeratin 19 and p63) in in situ and invasive cutaneous epithelial lesions
    Ossama Abbas
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
    Mod Pathol 24:90-7. 2011
  9. doi Immunohistochemistry with a mutation-specific monoclonal antibody as a screening tool for the BRAFV600E mutational status in primary cutaneous malignant melanoma
    John K Feller
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
    Mod Pathol 26:414-20. 2013
  10. doi Adenomatous eccrine metaplasia--a novel reaction pattern
    Claudine Yap Silva
    Department of Dermatology, Dermatopathology Section, Boston University School of Medicine, Boston, MA 02118, USA
    Am J Dermatopathol 34:47-53. 2012

Collaborators

  • Mai P Hoang
  • Jag Bhawan
  • Daniel D Miller
  • Marinya Pongpudpunth
  • Adam Lerner
  • Michael R Green
  • Thomas M RĂ¼nger
  • L J Goldberg
  • Susan M Sweeney
  • W A High
  • Ossama Abbas
  • Claudine Yap Silva
  • John K Feller
  • Ron Yaar
  • Olga Pozdnyakova
  • Shi Yang
  • Stefan M Schieke
  • Minggang Fang
  • Phyu P Aung
  • Reza S Jacob
  • Deon Wolpowitz
  • Andrew Emley
  • Joanna E Richards
  • Yue Yu
  • Arash Ronaghy
  • Marie France Demierre
  • Lauren Alberta-Wszolek
  • Karen A Dresser
  • Jeremy S Bordeaux
  • Mikhail Lisovsky
  • Karen Wiss
  • Grace Fong
  • Victoria Coburn
  • Sean F Pattee
  • Nicole R Leboeuf
  • Vishesh Chhibber
  • Narendra Wajapeyee
  • Meenakshi Batrani
  • Fen Xia
  • Ching Man Virbasius
  • Jennifer G Powers
  • Mohammed A Sharaf
  • Gary Mendese
  • Emmy Graber
  • Rufus W Burlingame
  • Lisa P Nguyen
  • Karen Rothman
  • Kavitha Reddy
  • Rita A Blanchard
  • Nikki A Levin
  • Alyse M Mousette
  • Laura Capaldi
  • Payal Kapur
  • Meghan O'Brien
  • Arash Radfar
  • Yuval B Nitzan
  • Mary E Maloney
  • Stephen Lyle
  • Jeremy Bordeaux
  • David Snook

Detail Information

Publications39

  1. ncbi Morphea-like tattoo reaction
    Meera Mahalingam
    Quest Diagnostics Incorporated, Cambridge, MA 02139, USA
    Am J Dermatopathol 24:392-5. 2002
    ..Occasionally, the dermal infiltrate may be so dense as to suggest a diagnosis of cutaneous lymphoma. We report an unusual tattoo reaction that mimicked morphea histologically...
  2. ncbi Atypical pilar leiomyoma: cutaneous counterpart of uterine symplastic leiomyoma?
    M Mahalingam
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine Boston, Massachusetts, USA
    Am J Dermatopathol 23:299-303. 2001
    ..This study suggests that cutaneous leiomyomas may exhibit bizarre or "symplastic" patterns analogous to their uterine counterparts...
  3. ncbi Metastatic papillary carcinoma of the thyroid
    M Mahalingam
    Quest Diagnostics Incorporated, Cambridge, MA 02139, USA
    J Cutan Pathol 31:509-12. 2004
    ..Cutaneous metastases from thyroid carcinomas, although uncommon, have been previously reported and are usually found in association with evidence of disseminated disease...
  4. ncbi Follicular acantholysis: a subtle clue to the early diagnosis of pemphigus vulgaris
    M Mahalingam
    Quest Diagnostics Incorporated, Cambridge, Massachusetts, USA
    Am J Dermatopathol 27:237-9. 2005
    ..This case report of acantholysis restricted to the follicular epithelium as a subtle histologic manifestation of the disease, draws attention to the pitfalls encountered in the histologic diagnosis of early cases of pemphigus vulgaris...
  5. doi Mixed versus pure variants of desmoplastic melanoma: a genetic and immunohistochemical appraisal
    Daniel D Miller
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
    Mod Pathol 25:505-15. 2012
    ..Increased CD117 staining in the mixed variant suggests that alterations in the KIT protein may be involved in tumor progression. In addition, the proliferative index of the mixed variant was higher than that of the pure variant...
  6. doi An immunohistochemical comparison of cytokeratin 7, cytokeratin 15, cytokeratin 19, CAM 5.2, carcinoembryonic antigen, and nestin in differentiating porocarcinoma from squamous cell carcinoma
    Meera Mahalingam
    Department of Dermatology, Dermatopathology Section, Boston University School of Medicine, Boston, MA 02118, USA
    Hum Pathol 43:1265-72. 2012
    ..The diagnostic sensitivity and specificity appear to be significantly improved using a selected panel of immunohistochemical stains that include cytokeratin 7, cytokeratin 19, and nestin...
  7. doi Nestin-positive stem cells in neurofibromas from patients with neurofibromatosis type 1-tumorigenic or incidental?
    Marinya Pongpudpunth
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, MA 02118, USA
    Am J Dermatopathol 32:574-7. 2010
    ..Recently, we found discrete foci of melanin deposits but diffuse positivity with MART-1/MelanA in a neurofibroma from a patient with neurofibromatosis type 1 (NF1)...
  8. doi Stem cell markers (cytokeratin 15, cytokeratin 19 and p63) in in situ and invasive cutaneous epithelial lesions
    Ossama Abbas
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
    Mod Pathol 24:90-7. 2011
    ..In summary, our findings expand the neoplasms which involve stem cells to include cutaneous epithelial malignancies. Differential localization of each of these markers argues in favor of stem cell heterogeneity...
  9. doi Immunohistochemistry with a mutation-specific monoclonal antibody as a screening tool for the BRAFV600E mutational status in primary cutaneous malignant melanoma
    John K Feller
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
    Mod Pathol 26:414-20. 2013
    ..Findings from the current study support the potential use of immunohistochemistry as an ancillary screening tool to assess the BRAFV600E mutation status in primary cutaneous melanoma...
  10. doi Adenomatous eccrine metaplasia--a novel reaction pattern
    Claudine Yap Silva
    Department of Dermatology, Dermatopathology Section, Boston University School of Medicine, Boston, MA 02118, USA
    Am J Dermatopathol 34:47-53. 2012
    ....
  11. doi Perineural involvement: what does it mean?
    Arash Ronaghy
    Department of Dermatology, Dermatopathology Section, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA
    Am J Dermatopathol 32:469-76. 2010
    ..Recognition of the spectrum of benign processes that may resemble perineural involvement may help prevent diagnostic confusion, misdiagnosis, and overly aggressive treatment...
  12. doi Epidermotropic metastatic mucoepidermoid carcinoma
    Ossama Abbas
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA
    Am J Dermatopathol 32:505-8. 2010
    ..In this report, we present a case of MEC presenting as a cutaneous metastasis. A histologic feature unique to this case was epidermotropism, previously not noted in either metastatic or primary MEC...
  13. doi D2-40 expression in primary scarring and nonscarring alopecia
    Meera Mahalingam
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA
    Am J Dermatopathol 32:427-31. 2010
    ....
  14. doi c-myc and cutaneous vascular neoplasms
    John K Feller
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
    Am J Dermatopathol 35:364-9. 2013
    ..This comprehensive review outlines the structure, normal functions, and effects of the deregulated expression of c-myc with particular emphasis on its role in angiogenesis and select cutaneous vascular neoplasms...
  15. doi Desmoplasia: not always a bad thing
    Ossama Abbas
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
    Histopathology 58:643-59. 2011
    ..Examples of benign and malignant cutaneous neoplasms associated with the desmoplastic reaction pattern will be included...
  16. doi Fibroblast-activation protein: a single marker that confidently differentiates morpheaform/infiltrative basal cell carcinoma from desmoplastic trichoepithelioma
    Ossama Abbas
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA, USA
    Mod Pathol 23:1535-43. 2010
    ..In summary, findings from this study underscore the use of fibroblast-activation protein as a histologic adjunct in confidently differentiating morpheaform/infiltrative basal cell carcinoma from desmoplastic trichoepithelioma...
  17. doi The diagnostic utility of immunohistochemistry in distinguishing primary skin adnexal carcinomas from metastatic adenocarcinoma to skin: an immunohistochemical reappraisal using cytokeratin 15, nestin, p63, D2-40, and calretinin
    Meera Mahalingam
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02114, USA
    Mod Pathol 23:713-9. 2010
    ..Positive staining with all three markers argues in favor of a primary cutaneous adnexal neoplasm...
  18. doi Nests with numerous SOX10 and MiTF-positive cells in lichenoid inflammation: pseudomelanocytic nests or authentic melanocytic proliferation?
    Claudine Yap Silva
    Department of Dermatology, Dermatopathology Section, Boston University School of Medicine, Boston, MA 02118, USA
    J Cutan Pathol 38:797-800. 2011
    ....
  19. doi Expression of stem-cell markers (cytokeratin 15 and nestin) in primary adnexal neoplasms-clues to etiopathogenesis
    Meera Mahalingam
    Department of Dermatology, Boston University School of Medicine, MA, USA
    Am J Dermatopathol 32:774-9. 2010
    ..The overlap in histopathologic features and immunoprofile of eccrine and apocrine neoplasms confounds basic issues relating to lineage of these entities...
  20. pmc MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair
    Minggang Fang
    Howard Hughes Medical Institute, Programs in Gene Function and Expression and Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Mol Cell Biol 33:2635-47. 2013
    ..Collectively, our results indicate that MEN1 is a melanoma tumor suppressor that functions by stimulating the transcription of genes involved in HR-directed DNA repair...
  21. doi Primary cutaneous CD56 positive lymphoma: a diagnostic conundrum in an unusual case of lymphoma
    Stefan M Schieke
    Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
    J Cutan Pathol 39:540-4. 2012
    ....
  22. doi Levamisole-induced vasculopathy: a report of 2 cases and a novel histopathologic finding
    Reza S Jacob
    Department of Dermatology, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA
    Am J Dermatopathol 34:208-13. 2012
    ..Our 2 cases reaffirm that neutropenia may precede the cutaneous eruption of LIVEN. Case 2 extends the spectrum of histopathologic findings to include the novel phenomenon of neovascularization-hitherto unreported in this entity...
  23. doi Reactive granular histiocytosis secondary to arthroplasty prosthesis: a novel reaction pattern
    Daniel D Miller
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
    J Cutan Pathol 39:558-61. 2012
    ..Dermatopathologists should be cognizant of this uncommon reaction pattern to avoid mistaking it for a neoplastic process...
  24. doi When dead cells tell tales-cutaneous involvement by precursor T-cell acute lymphoblastic lymphoma with an uncommon phenotype
    Ron Yaar
    Department of Dermatology, Boston University School of Medicine, MA, USA
    Am J Dermatopathol 32:183-6. 2010
    ..Features unique to this case include the cutaneous presentation and the immunophenotype-absence of CD4, CD8, and TdT with expression of CD34-both highly unusual features for pre-T ALL...
  25. doi Anaplastic Kaposi's sarcoma: an uncommon histologic phenotype with an aggressive clinical course
    Yue Yu
    Department of Dermatology, Boston University School of Medicine, Boston, MA, USA
    J Cutan Pathol 37:1088-91. 2010
    ..Our case underscores the aggressive clinical course of this uncommon histologic variant of KS and its recalcitrant clinical behavior...
  26. doi Somatic mutations in GNAQ in amelanotic/hypomelanotic blue nevi
    Andrew Emley
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA
    Hum Pathol 42:136-40. 2011
    ..Activation of this pathway is a consequence of multiple triggers-one of which is a mutation in the GNAQ gene, whereas the other is yet to be identified...
  27. doi Apoptosis and in situ and invasive squamous cell carcinoma in sun-exposed sites
    Phyu P Aung
    Department of Dermatology, Dermatopathology Section, Boston University School of Medicine, Boston, MA and Department of Pathology, Boston University School of Medicine, Boston, MA
    Am J Dermatopathol 35:797-803. 2013
    ..Expression of Bak in 100% of HPV-containing lesions from sun-exposed sites suggests that the virus does not abrogate UV-induced apoptosis...
  28. doi Morphometric analyses of elastic tissue fibers in dermatofibroma: clues to etiopathogenesis?
    Marinya Pongpudpunth
    Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA, USA
    J Cutan Pathol 36:1083-8. 2009
    ..The goal of this study was to ascertain the density of elastic tissue fibers in DF in an effort to investigate whether this provides an insight into its etiopathogenesis...
  29. ncbi Prognostic value of E-cadherin, beta-catenin, CD44v6, and HER2/neu in metastatic cutaneous adenocarcinoma
    Olga Pozdnyakova
    Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Arch Pathol Lab Med 133:1285-90. 2009
    ....
  30. ncbi Linear IgA bullous dermatosis following influenza vaccination
    Lauren Alberta-Wszolek
    Division of Dermatology, Department of Medicine, UMass Memorial Healthcare, Worcester, Massachusetts, USA
    Dermatol Online J 15:3. 2009
    ..Most cases are idiopathic but medications, infections, and malignancies have also been reported to induce LABD. We report the case of a 54-year-old woman who developed LABD shortly after receiving an influenza vaccination...
  31. ncbi Verrucous carcinoma of the scalp
    Sean F Pattee
    Department of Medicine, Division of Dermatology, University of Massachusetts Memorial Medical Center, Worcester, Massachusetts, USA
    J Am Acad Dermatol 56:506-7. 2007
    ..Human papillomaviruses, predominately types 6 and 11, have been associated with some case reports. We present a case of verrucous carcinoma arising on the scalp with negative human papillomavirus testing in a relatively young patient...
  32. doi Congenital Darier disease
    Grace Fong
    J Am Acad Dermatol 59:S50-1. 2008
  33. doi Clinicopathologic challenge. Disseminated fusariosis
    Jeremy S Bordeaux
    University of Massachusetts Medical School, USA
    Int J Dermatol 47:13-4. 2008
  34. ncbi Cutaneous oncocytoma - a report of three cases and review of the literature
    Victoria Coburn
    Department of Pathology, UMass Medical School, Worcester, MA, USA
    J Cutan Pathol 34:355-9. 2007
    ..Although some believe that oncocytomas are locally aggressive lesions, our cases indicate that their clinical course is perhaps as banal as their histology...
  35. ncbi Ductal eccrine carcinoma with squamous differentiation: apropos a case
    Vishesh Chhibber
    Department of Pathology, UMass Medical School, Worcester, MA 01605, USA
    J Cutan Pathol 34:503-7. 2007
    ..As the distinction between these two neoplasms is crucial to patient management, we highlight the histologic features of this uncommon entity to highlight the potential diagnostic pitfalls...
  36. ncbi Apolipoprotein D in CD34-positive and CD34-negative cutaneous neoplasms: a useful marker in differentiating superficial acral fibromyxoma from dermatofibrosarcoma protuberans
    Mikhail Lisovsky
    Department of Pathology, UMass Medical School, Worcester, MA, USA
    Mod Pathol 21:31-8. 2008
    ....
  37. ncbi CD99 - much ado about nothing?
    Olga Pozdnyakova
    J Cutan Pathol 35:86-7. 2008
  38. ncbi Microcystic adnexal carcinoma: an immunohistochemical reappraisal
    Mai P Hoang
    Department of Pathology, UMass Medical School, Worcester, MA, USA
    Mod Pathol 21:178-85. 2008
    ..Our experience indicates that microcystic adnexal carcinoma and desmoplastic trichoepithelioma have a similar immunohistochemical profile that is, CK15+ and BerEP4+/-; thus, additional studies are needed to separate these two entities...
  39. ncbi Acanthomatous superficial sebaceous hamartoma? A study of six cases with clarification of the nomenclature
    Nicole R Leboeuf
    Department of Medicine, University of Massachusetts Medical School UMMS, Worcester, MA 01605, USA
    J Cutan Pathol 34:865-70. 2007
    ....