Alexander Wei

Summary

Affiliation: Purdue University
Country: USA

Publications

  1. pmc Challenges and opportunities in the advancement of nanomedicines
    Alexander Wei
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907, USA
    J Control Release 164:236-46. 2012
  2. pmc Hyperthermic effects of gold nanorods on tumor cells
    Terry B Huff
    Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA
    Nanomedicine (Lond) 2:125-32. 2007
  3. pmc Differential response of macrophages to core-shell Fe3O4@Au nanoparticles and nanostars
    Wei Xia
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907 2084, USA
    Nanoscale 4:7143-8. 2012
  4. doi request reprint Gold nanorods: multifunctional agents for cancer imaging and therapy
    Alexander Wei
    Department of Chemistry, Purdue University, West Lafayette, IN, USA
    Methods Mol Biol 624:119-30. 2010
  5. pmc Gold nanorods as contrast agents for biological imaging: optical properties, surface conjugation and photothermal effects
    Ling Tong
    Department of Chemistry, Purdue University, West Lafayette, IN, USA
    Photochem Photobiol 85:21-32. 2009
  6. pmc Optical imaging with dynamic contrast agents
    Qingshan Wei
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907 2084, USA
    Chemistry 17:1080-91. 2011
  7. doi request reprint Label-free detection of a bacterial pathogen using an immobilized siderophore, deferoxamine
    Youngsoon Kim
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    Lab Chip 12:971-6. 2012
  8. pmc Detoxification of gold nanorods by treatment with polystyrenesulfonate
    Alexei P Leonov
    Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA
    ACS Nano 2:2481-8. 2008
  9. pmc Assembly of dithiocarbamate-anchored monolayers on gold surfaces in aqueous solutions
    Heng Zhu
    Department of Chemistry and Birck Nanotechnology Center, Purdue University, West Lafayette, Indiana 47907, USA
    Langmuir 24:8660-6. 2008
  10. pmc Plasmon-resonant nanoparticles and nanostars with magnetic cores: synthesis and magnetomotive imaging
    Hyon Min Song
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907 2084, USA
    ACS Nano 4:5163-73. 2010

Collaborators

  • Gang Cheng
  • Ji Xin Cheng
  • Maria S Sepúlveda
  • Yan Zhao
  • Hugo Ochoa-Acuña
  • Yu Gao
  • Heng Zhu
  • Renhua Fan
  • Jean Chmielewski
  • Wei Xia
  • Kenneth Ritchie
  • Stephan T Stern
  • Qingshan Wei
  • Jonathan G Mehtala
  • Panuwat Padungros
  • Laura Alberch
  • Zhao Tang
  • David P Lyvers
  • RunHui Liu
  • Alexei P Leonov
  • Terry B Huff
  • Philip S Low
  • Hyon Min Song
  • Ling Tong
  • Jiejun Gao
  • Matthew C Stensberg
  • Jeong Mi Moon
  • Avijit K Adak
  • Youngsoon Kim
  • Matthew Charles Stensberg
  • Avijit Kumar Adak
  • Quy K Ong
  • Matthew N Hansen
  • Cecon T Mahapatra
  • Christopher Klinkhamer
  • Chulhong Kim
  • Shou Zhao
  • Dmitry Y Zemlyanov
  • Eric S McLamore
  • Gowri Yale
  • Joann P Max
  • Mansik Jeon
  • Sandra Torregrosa-Allen
  • Hari R Khatri
  • D Marshall Porterfield
  • Naveen Kadasala
  • Rajtarun Madangopal
  • Bennett D Elzey
  • Matthew D Casselman
  • Jenna Rickus
  • J William Boley
  • Ronald Reifenberger
  • George T Chiu
  • Oscar Morales-Collazo
  • Ronald G Reifenberger
  • Xuehua Li
  • Eric Scott McLamore
  • Seung kee Seo
  • Fabien P Boulineau
  • David Marshall Porterfield
  • Sumith Kularatne
  • Ning Ding
  • Jyothi Thundimadathil
  • Dongmyung Oh
  • Jacob A Hale
  • Jiwen Zheng
  • Vladimir M Shalaev
  • Jesús M Hernández-Torres
  • Karl V Wood
  • Hongling Han
  • Jeffrey D Clogston
  • Alexander V Kildishev
  • Anil K Patri
  • Chamnongsak Chanthamontri
  • Scott A McLuckey

Detail Information

Publications31

  1. pmc Challenges and opportunities in the advancement of nanomedicines
    Alexander Wei
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907, USA
    J Control Release 164:236-46. 2012
    ....
  2. pmc Hyperthermic effects of gold nanorods on tumor cells
    Terry B Huff
    Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA
    Nanomedicine (Lond) 2:125-32. 2007
    ....
  3. pmc Differential response of macrophages to core-shell Fe3O4@Au nanoparticles and nanostars
    Wei Xia
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907 2084, USA
    Nanoscale 4:7143-8. 2012
    ..These observations show that differences in NP size and shape are sufficient to produce diverse responses in macrophages following uptake...
  4. doi request reprint Gold nanorods: multifunctional agents for cancer imaging and therapy
    Alexander Wei
    Department of Chemistry, Purdue University, West Lafayette, IN, USA
    Methods Mol Biol 624:119-30. 2010
    ..This can be accomplished by using polystyrenesulfonate (PSS) as a sorbent for removing CTAB, and in situ dithiocarbamate formation for introducing chemisorptive ligands onto GNR surfaces...
  5. pmc Gold nanorods as contrast agents for biological imaging: optical properties, surface conjugation and photothermal effects
    Ling Tong
    Department of Chemistry, Purdue University, West Lafayette, IN, USA
    Photochem Photobiol 85:21-32. 2009
    ..The combination of plasmon-resonant optical properties, intense local photothermal effects and robust surface chemistry render gold NRs as promising theragnostic agents...
  6. pmc Optical imaging with dynamic contrast agents
    Qingshan Wei
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907 2084, USA
    Chemistry 17:1080-91. 2011
    ..Dynamic contrast is an emerging topic with considerable room for development, both with respect to molecular or nanoscale probes for signal modulation, and also to methods for more efficient image processing and editing...
  7. doi request reprint Label-free detection of a bacterial pathogen using an immobilized siderophore, deferoxamine
    Youngsoon Kim
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    Lab Chip 12:971-6. 2012
    ....
  8. pmc Detoxification of gold nanorods by treatment with polystyrenesulfonate
    Alexei P Leonov
    Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA
    ACS Nano 2:2481-8. 2008
    ....
  9. pmc Assembly of dithiocarbamate-anchored monolayers on gold surfaces in aqueous solutions
    Heng Zhu
    Department of Chemistry and Birck Nanotechnology Center, Purdue University, West Lafayette, Indiana 47907, USA
    Langmuir 24:8660-6. 2008
    ..These analyses establish a practical range of conditions for preparing DAMs from polar amines using in situ DTC formation...
  10. pmc Plasmon-resonant nanoparticles and nanostars with magnetic cores: synthesis and magnetomotive imaging
    Hyon Min Song
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907 2084, USA
    ACS Nano 4:5163-73. 2010
    ....
  11. pmc Stereoelectronic factors in the stereoselective epoxidation of glycals and 4-deoxypentenosides
    Laura Alberch
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907 2084, United States
    J Org Chem 76:2532-47. 2011
    ....
  12. pmc Bishydrazide glycoconjugates for lectin recognition and capture of bacterial pathogens
    Avijit Kumar Adak
    Department of Chemistry, Purdue University, West Lafayette, Indiana, United States
    Bioconjug Chem 21:2065-75. 2010
    ..A detection limit of 10³ cfu/mL is demonstrated, using a recently introduced method based on optical pattern recognition...
  13. doi request reprint Gold nanorod arrays as plasmonic cavity resonators
    David P Lyvers
    Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA
    ACS Nano 2:2569-76. 2008
    ..Removal of the metal baseplate is predicted to result in resonant transmission through the Au nanorod arrays, at frequencies defined by half-wave modes within the open-ended cavities...
  14. pmc Glycal assembly by the in situ generation of glycosyl dithiocarbamates
    Panuwat Padungros
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, USA
    Org Lett 14:3380-3. 2012
    ..The coupling efficiency can be further enhanced by in situ benzoylation, as illustrated in an 11-step synthesis of a branched hexasaccharide from glucals in 28% isolated yield and just four chromatographic purifications...
  15. doi request reprint Silver nanoparticle-specific mitotoxicity in Daphnia magna
    Matthew C Stensberg
    Department of Agriculture and Biological Engineering, Purdue University, West Lafayette, IN, USA
    Nanotoxicology 8:833-42. 2014
    ..We propose that the MOT of each form of silver are complementary, and can act in synergy to produce a greater toxic response overall...
  16. pmc Synthesis and reactivity of 4'-deoxypentenosyl disaccharides
    Panuwat Padungros
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907 2084, United States
    J Org Chem 79:4878-91. 2014
    ..These studies support a novel approach to oligosaccharide synthesis, in which the stereochemical configuration of the terminal 4'-DP unit is established at a post-glycosylative stage. ..
  17. pmc Glycosyl dithiocarbamates: β-selective couplings without auxiliary groups
    Panuwat Padungros
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States
    J Org Chem 79:2611-24. 2014
    ..We provide evidence that the directing effect is mediated by the C2 hydroxyl itself via the putative formation of a cis-fused bicyclic intermediate. ..
  18. doi request reprint Label-free detection of Staphylococcus aureus captured on immutable ligand arrays
    Avijit K Adak
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States
    ACS Appl Mater Interfaces 5:6404-11. 2013
    ..aureus, with a limit of detection between 10(2) and 10(3) cfu/mL. Inkjet printing provides independent control over array periodicity, enabling FFT signals to be assigned to specific frequencies in reciprocal k-space...
  19. pmc syn additions to 4alpha-epoxypyranosides: synthesis of L-idopyranosides
    Gang Cheng
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907 2084, USA
    Org Lett 9:4849-52. 2007
    ....
  20. pmc Gyromagnetic imaging: dynamic optical contrast using gold nanostars with magnetic cores
    Qingshan Wei
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907 2084, USA
    J Am Chem Soc 131:9728-34. 2009
    ..The gyromagnetically active nanostars do not cause a loss in viability, and can even have a mild stimulatory effect on cell growth...
  21. pmc Toxicological studies on silver nanoparticles: challenges and opportunities in assessment, monitoring and imaging
    Matthew Charles Stensberg
    Department of Agricultural and Biological Engineering, Purdue University, 225 S University St, West Lafayette, IN 47907, USA
    Nanomedicine (Lond) 6:879-98. 2011
    ..We include several proposed mechanisms of cytotoxicity based on such studies, as well as new opportunities for investigating the uptake and fate of Ag NPs in living systems...
  22. pmc Metal-mesh lithography
    Zhao Tang
    Department of Chemistry, 560 Oval Drive, Purdue University, West Lafayette, Indiana 47907 2084, USA
    ACS Appl Mater Interfaces 3:4812-8. 2011
    ..MML can be combined with other surface chemistry and lift-off methods to create functional microarrays for diverse applications, such as periodic islands of gold nanorods and patterned corrals for fibroblast cell cultures...
  23. pmc Citrate-stabilized gold nanorods
    Jonathan G Mehtala
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907 2084, United States
    Langmuir 30:13727-30. 2014
    ..The reliability of the surface exchange process supports the systematic analysis of ligand structure on the hydrodynamic size of GNRs, as described in a companion paper. ..
  24. doi request reprint Nanosilver-coated socks and their toxicity to zebrafish (Danio rerio) embryos
    Jiejun Gao
    Department of Forestry and Natural Resources and Bindley Biosciences Center, Purdue University, West Lafayette, IN 47907, United States
    Chemosphere 119:948-52. 2015
    ..More studies are needed to evaluate the toxicity of the myriad of AgNP-coated commercial products that are now estimated to be close to 500...
  25. pmc Synergistic effects of cisplatin chemotherapy and gold nanorod-mediated hyperthermia on ovarian cancer cells and tumors
    Jonathan G Mehtala
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907 2084, USA
    Nanomedicine (Lond) 9:1939-55. 2014
    ..The synergistic effects of gold nanorod (GNR)-mediated mild hyperthermia (MHT; 42-43°C) and cisplatin (CP) activity was evaluated against chemoresistant SKOV3 cells in vitro and with a tumor xenograft model...
  26. pmc Nanometric resolution in the hydrodynamic size analysis of ligand-stabilized gold nanorods
    Jonathan G Mehtala
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States
    Langmuir 30:13737-43. 2014
    ..The precision of NTA (relative standard deviation 10-12%, standard error <2%) is sufficient to allow differences in the hydrodynamic size of coated GNRs to be interpreted in terms of surfactant structure and conformation. ..
  27. pmc Solid-phase synthesis of alpha-glucosamine sulfoforms with fragmentation analysis by tandem mass spectrometry
    RunHui Liu
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907 2084, USA
    J Org Chem 73:6059-72. 2008
    ..In particular, fragmentation analysis can easily distinguish GlcN sulfoforms bearing the relatively rare 3- O-sulfate from isomers with the more common 6- O-sulfate...
  28. pmc Sulfoform generation from an orthogonally protected disaccharide
    RunHui Liu
    Department of Chemistry, Purdue University, West Lafayette, IN 47907 2084, USA
    Carbohydr Res 355:19-27. 2012
    ..The modular deprotection-sulfonation sequences can be performed with efficient recovery of the polysulfate products, and avoids complications associated with heterogeneous reactivity in solid-phase synthesis...
  29. pmc Controlling the cellular uptake of gold nanorods
    Terry B Huff
    Department of Chemistry and Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana 47907, USA
    Langmuir 23:1596-9. 2007
    ....
  30. pmc Uniform gold nanorod arrays from polyethylenimine-coated alumina templates
    Jeong Mi Moon
    Department of Chemistry, 560 Oval Drive, Purdue University, West Lafayette, Indiana 47907 2084, USA
    J Phys Chem B 109:23336-41. 2005
    ..Reflectance spectroscopy reveals a collective plasmon mode with a maximum near 1.2 microm, in accord with recent calculations for 2D arrays of closely spaced cylindrical nanoparticles...
  31. pmc Fabrication of anisotropic metal nanostructures using innovations in template-assisted lithography
    Zhao Tang
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907 2084, United States
    ACS Nano 6:998-1003. 2012
    ..We focus specifically on C-shaped nanostructures (nanocrescents and split-ring resonators), which can be fabricated by using novel variants of shadow-mask lithography, substrate etching, or microcontact printing...

Research Grants3

  1. Plasmon-Resonant Nanorods as Contrast Agents
    Alexander Wei; Fiscal Year: 2007
    ..The OCT-nanorod technology is anticipated to have broad application as an integrated, noninvasive system for medical concerns which require image-guided intervention. ..
  2. Glycosylated Nanoparticles to Inhibit Receptor Clustering
    Alexander Wei; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  3. Advances in Nanomedicine Symposium at the 236th National Meeting of the American
    Alexander Wei; Fiscal Year: 2008
    ..engineering [unreadable] [unreadable] (ii) Multifunctional nanoparticles for targeted imaging and therapy (theragnostics) [unreadable] [unreadable] (iii) Nanomaterials for drug delivery [unreadable] [unreadable] [unreadable] [unreadable]..