Connie Weaver

Summary

Affiliation: Purdue University
Country: USA

Publications

  1. ncbi request reprint Soy isoflavones and bone health: the relationship is still unclear
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana, USA
    J Nutr 135:1243-7. 2005
  2. ncbi request reprint Bone mineral and predictors of bone mass in white, Hispanic, and Asian early pubertal girls
    C M Weaver
    Department of Foods and Nutrition, Purdue University, 700 W State Street, West Lafayette, IN 47907 2059, USA
    Calcif Tissue Int 81:352-63. 2007
  3. pmc Flavonoid intake and bone health
    Connie M Weaver
    Department of Nutrition Science, Purdue University, West Lafayette, Indiana 47907 2059, USA
    J Nutr Gerontol Geriatr 31:239-53. 2012
  4. pmc Bioactive foods and ingredients for health
    Connie M Weaver
    Department of Nutrition Science, Purdue University, West Lafayette, IN
    Adv Nutr 5:306S-11S. 2014
  5. ncbi request reprint Calcium supplementation: is protecting against osteoporosis counter to protecting against cardiovascular disease?
    Connie M Weaver
    Department of Nutrition Science, Purdue University, 700 W State Street, West Lafayette, IN, 47907, USA
    Curr Osteoporos Rep 12:211-8. 2014
  6. pmc Calcium requirements and metabolism in Chinese-American boys and girls
    Lu Wu
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN, USA
    J Bone Miner Res 25:1842-9. 2010
  7. pmc Potassium and health
    Connie M Weaver
    Department of Nutrition Science, Purdue University, West Lafayette, IN, USA
    Adv Nutr 4:368S-77S. 2013
  8. pmc White vegetables: a forgotten source of nutrients: Purdue roundtable executive summary
    Connie Weaver
    Department of Nutrition Science, Purdue University, West Lafayette, IN, USA
    Adv Nutr 4:318S-26S. 2013
  9. doi request reprint Novel fibers increase bone calcium content and strength beyond efficiency of large intestine fermentation
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907, USA
    J Agric Food Chem 58:8952-7. 2010
  10. pmc Vitamin D interactions with soy isoflavones on bone after menopause: a review
    Clara Y Park
    Department of Nutrition Science, Purdue University, 700 W State St, West Lafayette, IN 47907, USA
    Nutrients 4:1610-21. 2012

Research Grants

  1. Calcium, Dairy, and Body Fat in Adolescents
    Connie Weaver; Fiscal Year: 2006
  2. CALCIUM METABOLISM IN ADOLESCENT BOYS
    Connie Weaver; Fiscal Year: 2002
  3. Calcium Metabolism in Mexican American Adolescents
    Connie M Weaver; Fiscal Year: 2010
  4. 24,25-DIHYDROXYVITAMIN D: MARKER OF SALT SENSITIVITY
    Connie Weaver; Fiscal Year: 2001
  5. CALCIUM METABOLISM IN ADOLESCENT BOYS
    Connie Weaver; Fiscal Year: 2001
  6. SODIUM INTAKE AND CALCIUM RETENTION IN ADOLESCENT GIRLS
    Connie Weaver; Fiscal Year: 2001
  7. CALCIUM METABOLISM in ASIAN AMERICAN ADOLESCENTS
    Connie Weaver; Fiscal Year: 2004
  8. Calcium, Dairy, and Body Fat in Adolescents
    Connie Weaver; Fiscal Year: 2004
  9. Calcium, Dairy, and Body Fat in Adolescents
    Connie Weaver; Fiscal Year: 2005
  10. CALCIUM METABOLISM IN ASIAN GIRLS AND POSTMENOPAUSAL WOMEN
    Connie Weaver; Fiscal Year: 2005

Collaborators

Detail Information

Publications79

  1. ncbi request reprint Soy isoflavones and bone health: the relationship is still unclear
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana, USA
    J Nutr 135:1243-7. 2005
    ..This overview will summarize these discrepancies and will suggest future studies to clarify the conditions under which these dietary substances can be helpful for bones...
  2. ncbi request reprint Bone mineral and predictors of bone mass in white, Hispanic, and Asian early pubertal girls
    C M Weaver
    Department of Foods and Nutrition, Purdue University, 700 W State Street, West Lafayette, IN 47907 2059, USA
    Calcif Tissue Int 81:352-63. 2007
    ..Bone size explained most of the racial/ethnic differences in BMC, although behavioral indicators were also significant predictors of BMC...
  3. pmc Flavonoid intake and bone health
    Connie M Weaver
    Department of Nutrition Science, Purdue University, West Lafayette, Indiana 47907 2059, USA
    J Nutr Gerontol Geriatr 31:239-53. 2012
    ..Future research is needed to determine which of the flavonoids and their metabolites are most effective and at what dose, as well as the mechanism of modulating cellular events, in order to set priorities for clinical trials...
  4. pmc Bioactive foods and ingredients for health
    Connie M Weaver
    Department of Nutrition Science, Purdue University, West Lafayette, IN
    Adv Nutr 5:306S-11S. 2014
    ..Policy processes are needed to establish the level of evidence needed to determine dietary advice and policy recommendations and to set research agendas...
  5. ncbi request reprint Calcium supplementation: is protecting against osteoporosis counter to protecting against cardiovascular disease?
    Connie M Weaver
    Department of Nutrition Science, Purdue University, 700 W State Street, West Lafayette, IN, 47907, USA
    Curr Osteoporos Rep 12:211-8. 2014
    ..At present, the current Recommended Dietary Allowances for calcium still appear to be a good target with potential risks for chronic disease if intakes fall too short or greatly exceed these recommendations. ..
  6. pmc Calcium requirements and metabolism in Chinese-American boys and girls
    Lu Wu
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN, USA
    J Bone Miner Res 25:1842-9. 2010
    ..Recommendations for calcium requirements should be lowered for Chinese-American adolescents...
  7. pmc Potassium and health
    Connie M Weaver
    Department of Nutrition Science, Purdue University, West Lafayette, IN, USA
    Adv Nutr 4:368S-77S. 2013
    ..Low potassium-to-sodium intake ratios are more strongly related to cardiovascular disease risk than either nutrient alone. This relationship deserves further attention for multiple target tissue endpoints...
  8. pmc White vegetables: a forgotten source of nutrients: Purdue roundtable executive summary
    Connie Weaver
    Department of Nutrition Science, Purdue University, West Lafayette, IN, USA
    Adv Nutr 4:318S-26S. 2013
    ..More research is needed to determine the health contributions of white vegetables as a source of nutrients and bioactive constituents and their bioavailability beyond the isolated components...
  9. doi request reprint Novel fibers increase bone calcium content and strength beyond efficiency of large intestine fermentation
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907, USA
    J Agric Food Chem 58:8952-7. 2010
    ....
  10. pmc Vitamin D interactions with soy isoflavones on bone after menopause: a review
    Clara Y Park
    Department of Nutrition Science, Purdue University, 700 W State St, West Lafayette, IN 47907, USA
    Nutrients 4:1610-21. 2012
    ..We discuss a possible synergistic effect of soy isoflavones and vitamin D on bone by affecting osteoblast and osteoclast formation and activity in postmenopausal women...
  11. ncbi request reprint Prebiotics enhance magnesium absorption and inulin-based fibers exert chronic effects on calcium utilization in a postmenopausal rodent model
    Leecole L Legette
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907, USA
    J Food Sci 77:H88-94. 2012
    ..All fibers improved magnesium absorption and retention in early and late metabolic balances; effects on magnesium metabolism were more pronounced than for calcium...
  12. ncbi request reprint Current calcium recommendations in North America
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 2059, USA
    Asia Pac J Clin Nutr 17:30-2. 2008
    ..Issues that are receiving attention currently include possible catch up growth, dairy vs. calcium intake, and how to establish optimal intakes...
  13. pmc Botanicals for age-related diseases: from field to practice
    Connie M Weaver
    Foods and Nutrition, Rutgers University, New Brunswick, NJ, USA
    Am J Clin Nutr 87:493S-7S. 2008
    ..Botanicals and their relation to bone antiresorptive capacity, cognitive function, vascular effects, and cancer are principal themes in our center...
  14. ncbi request reprint Dairy versus calcium carbonate in promoting peak bone mass and bone maintenance during subsequent calcium deficiency
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907 2059, USA
    J Bone Miner Res 24:1411-9. 2009
    ..4%) and a trend (p = 0.02) toward greater peak breaking force (17%). Thus, NFDMs improved bone measures during growth and protected bone against a subsequent period of calcium depletion compared with CaCO(3)...
  15. ncbi request reprint The role of nutrition on optimizing peak bone mass
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 2059, USA
    Asia Pac J Clin Nutr 17:135-7. 2008
    ..Dietary salt increases urinary calcium excretion. Exercise can enhance the effect of dietary calcium through enhanced bone geometry...
  16. pmc Vitamin D status and calcium metabolism in adolescent black and white girls on a range of controlled calcium intakes
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907 2059, USA
    J Clin Endocrinol Metab 93:3907-14. 2008
    ..There are limited data in adolescents on racial differences in relationships between dietary calcium intake, absorption, and retention and serum levels of calcium-regulating hormones...
  17. doi request reprint Should dairy be recommended as part of a healthy vegetarian diet? Point
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN, USA
    Am J Clin Nutr 89:1634S-1637S. 2009
    ..Overall, evidence suggests that being a lactovegetarian has greater health benefits and reduced health risks than being a vegan...
  18. pmc Antiresorptive effects of phytoestrogen supplements compared with estradiol or risedronate in postmenopausal women using (41)Ca methodology
    C M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907 2059, USA
    J Clin Endocrinol Metab 94:3798-805. 2009
    ..Isoflavones have been reported to protect bone from estrogen deficiency, but their modest effects on bone resorption have been difficult to measure with traditional analytical methods...
  19. ncbi request reprint Role of dairy beverages in the diet
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, 700 W State Street, West Lafayette, IN 47907 2059, USA
    Physiol Behav 100:63-6. 2010
    ..Concerns over milk consumption have focused on saturated fats historically. More research is needed to resolve potential concerns of milk consumption and risk of several disorders including ovarian cancer and soft tissue calcification...
  20. pmc Equol, via dietary sources or intestinal production, may ameliorate estrogen deficiency-induced bone loss
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
    J Nutr 140:1377S-9S. 2010
    ..In menopausal Western women, equol status did not affect the modest, but significant, reduction in bone resorption achieved with a soy isoflavone intervention...
  21. pmc Calcium, dairy products, and energy balance in overweight adolescents: a controlled trial
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN, USA
    Am J Clin Nutr 94:1163-70. 2011
    ..Dairy product and calcium consumption have been associated with modifying body fat and body weight in children and adults...
  22. ncbi request reprint Measuring calcium absorption and utilization in humans
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907 2059, USA
    Curr Opin Clin Nutr Metab Care 9:568-74. 2006
    ..Calcium dynamics are studied with the use of isotopic tracers. We also cover state-of-the-art methods for stable calcium isotope ratio analysis and offer insights on experimental design...
  23. doi request reprint Galactooligosaccharides improve mineral absorption and bone properties in growing rats through gut fermentation
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, 700 W State St, West Lafayette, IN 47907 2059, USA
    J Agric Food Chem 59:6501-10. 2011
    ..Regression modeling showed that GOS benefited calcium and magnesium utilization and vBMD through decreased cecal pH, increased cecal wall and content weight, and increased proportion of bifidobacteria...
  24. ncbi request reprint Dairy intakes affect bone density in the elderly
    Linda D McCabe
    Purdue University, West Lafayette, IN, USA
    Am J Clin Nutr 80:1066-74. 2004
    ..Race and sex differences in the effect of diet on bone mineral density (BMD) at the hip in the elderly are unknown...
  25. ncbi request reprint The health benefits of calcium citrate malate: a review of the supporting science
    Susan Reinwald
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
    Adv Food Nutr Res 54:219-346. 2008
    ....
  26. pmc Predictors of calcium retention in adolescent boys
    Kathleen M Hill
    Purdue University, Foods and Nutrition, 700 W State Street, West Lafayette, Indiana 47907 2059, USA
    J Clin Endocrinol Metab 93:4743-8. 2008
    ..The relationship between calcium (Ca) intake and Ca retention in adolescent boys was recently reported...
  27. pmc Bioavailability of gallic acid and catechins from grape seed polyphenol extract is improved by repeated dosing in rats: implications for treatment in Alzheimer's disease
    Mario G Ferruzzi
    Department of Food Science, Purdue University, West Lafayette, IN 47907, USA
    J Alzheimers Dis 18:113-24. 2009
    ..7 +/-45.9 and 576.7 +/- 227.7 pg/g in brain tissues from rats administered GSPE for 10 days. This study suggests that brain deposition of GA, C, and EC is affected by repeated dosing of GSPE...
  28. ncbi request reprint Racial differences in skeletal calcium retention in adolescent girls with varied controlled calcium intakes
    Michelle Braun
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
    Am J Clin Nutr 85:1657-63. 2007
    ..Higher bone mass in blacks than in whites has been related to greater calcium utilization efficiency. Dietary calcium requirements for maximal skeletal calcium accretion during puberty may differ between the races...
  29. doi request reprint Diet calcium level but not calcium supplement particle size affects bone density and mechanical properties in ovariectomized rats
    Mohammad Shahnazari
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
    J Nutr 139:1308-14. 2009
    ....
  30. pmc Supplemental dietary racemic equol has modest benefits to bone but has mild uterotropic activity in ovariectomized rats
    Leecole L Legette
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
    J Nutr 139:1908-13. 2009
    ..Dietary equol had no stimulatory effect on mammary gland epithelium. We conclude that in OVX rats, a dietary equol dose that had modest effect on bone also exerts mild uterotropic effects...
  31. ncbi request reprint Calcium bioavailability of calcium carbonate fortified soymilk is equivalent to cow's milk in young women
    Yongdong Zhao
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN, USA
    J Nutr 135:2379-82. 2005
    ..217 +/- 0.040), but both were higher (P < 0.05) than that of TCPSM (0.181 +/- 0.039). Our result suggests that calcium absorption is equivalent for CCSM and cow's milk at similar calcium loads...
  32. ncbi request reprint Calcium absorption from three salts and CaSO(4)-fortified bread in premenopausal women
    Berdine R Martin
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907 1264, USA
    J Agric Food Chem 50:3874-6. 2002
    ..0675 +/- 0.016). Calcium sulfate is a bioavailable fortificant for white bread that compares favorably with milk and two other salts...
  33. ncbi request reprint Biomarkers of bone health appropriate for evaluating functional foods designed to reduce risk of osteoporosis
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 1264, USA
    Br J Nutr 88:S225-32. 2002
    ..Use of a rare isotope, 41Ca, and accelerator mass spectrometry offers a new approach for assessing the ability of functional foods to suppress bone resorption...
  34. pmc Pharmacokinetics and tissue distribution of 14C-labeled grape polyphenols in the periphery and the central nervous system following oral administration
    Elsa M Janle
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907 2059, USA
    J Med Food 13:926-33. 2010
    ..Our observations indicate that some grape-derived polyphenolics do reach the brain, which suggests their potential value for applications in neurodegenerative disorders...
  35. ncbi request reprint Vitamin D requirements: current and future
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 2059, USA
    Am J Clin Nutr 80:1735S-9S. 2004
    ..So much new information on vitamin D and health has been collected since the requirements were set in 1997 that this nutrient is likely the most in need of revised requirements...
  36. ncbi request reprint Calcium retention in adolescent boys on a range of controlled calcium intakes
    Michelle Braun
    Purdue University, West Lafayette, IN, USA
    Am J Clin Nutr 84:414-8. 2006
    ..On average, boys develop larger skeletons than do girls, yet it is unknown whether the additional skeletal accretion in boys requires additional dietary calcium intake...
  37. ncbi request reprint Adolescence: the period of dramatic bone growth
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 1264, USA
    Endocrine 17:43-8. 2002
    ..Weight-bearing exercise can increase bone mass. Appropriate mineralization of the skeleton requires adequate dietary intakes of minerals involved in the formation of hydroxyapatite; the most likely to be deficient is calcium...
  38. ncbi request reprint Inulin, oligofructose and bone health: experimental approaches and mechanisms
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 2059, USA
    Br J Nutr 93:S99-103. 2005
    ..Chicory long-chain inulin and oligofructose enhance femoral Ca content, bone mineral density and Ca retention through enhanced Ca absorption and suppressed bone turnover rates, but it is not bone-promoting under all conditions...
  39. ncbi request reprint 2003 W.O. Atwater Memorial Lecture: Defining nutrient requirements from a perspective of bone-related nutrients
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 2059, USA
    J Nutr 133:4063-6. 2003
  40. ncbi request reprint Inulin effects on bioavailability of soy isoflavones and their calcium absorption enhancing ability
    Tasleem A Zafar
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907, USA
    J Agric Food Chem 52:2827-31. 2004
    ..01) when inulin was added to the diet containing isoflavones. We conclude that isoflavones enhance calcium absorption, without synergy from inulin, and that inulin decreases equol production...
  41. doi request reprint Bone seeking labels as markers for bone turnover: effect of dosing schedule on labeling various bone sites in rats
    Jennifer M K Cheong
    Department of Foods and Nutrition, Purdue University, 700 West State Street, West Lafayette, IN 47907 2059, USA
    Calcif Tissue Int 85:444-50. 2009
    ..The amount of label incorporation into bone was greater in bone sites that were more metabolically active and in all sites when closer vs farther from OVX...
  42. ncbi request reprint Cross-calibration of 45calcium kinetics against dynamic histomorphometry in a rat model to determine bone turnover
    Mohammad Shahnazari
    Department of Foods and Nutrition, Purdue University, 700 W State Street, West Lafayette, IN 47907, USA
    Bone 46:1238-43. 2010
    ..2% (34.2 vs. 23.8 mg/d and 10.4 vs. 5.1 mg/d, respectively, p<0.001). Our data suggest that Ca kinetic studies can be used reliably to rapidly detect changes in bone turnover at the whole skeletal level in response to interventions...
  43. ncbi request reprint Soy isoflavones and bone health: a double-edged sword?
    Susan Reinwald
    Department of Food Science, Purdue University, West Lafayette, Indiana 47907 2009, USA
    J Nat Prod 69:450-9. 2006
    ..The effects of chronic consumption of high levels of soy isoflavones at each life stage to assess risk-benefit ratios should be a high priority of research...
  44. pmc Tetracycline and calcium kinetics are comparable for estimating bone resorption in rats
    Yongdong Zhao
    Foods and Nutrition Department, Purdue University, West Lafayette, IN 47907, USA
    J Nutr 140:1704-9. 2010
    ..The tracers (45)Ca and (3)H-TC can be used interchangeably to determine bone resorption rates in OVX rats. Thus, both labels can be used to screen dietary and other interventions for beneficial effects on bone...
  45. ncbi request reprint Racial differences in calcium retention in response to dietary salt in adolescent girls
    Karin Wigertz
    Departments of Foods and Nutrition and of Statistics, Purdue University, West Lafayette, IN, USA
    Am J Clin Nutr 81:845-50. 2005
    ..The effect of dietary sodium on calcium retention and the influence of race have not been studied in adolescence, the life stage during which peak bone mass is accrued...
  46. ncbi request reprint Nondigestible oligosaccharides increase calcium absorption and suppress bone resorption in ovariectomized rats
    Tasleem A Zafar
    Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
    J Nutr 134:399-402. 2004
    ..We conclude that feeding NDO at 5.5 g/100 g for 21 d has a positive effect on calcium absorption and retention in ovariectomized rats...
  47. pmc An inflection point of serum 25-hydroxyvitamin D for maximal suppression of parathyroid hormone is not evident from multi-site pooled data in children and adolescents
    Kathleen M Hill
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47906, USA
    J Nutr 140:1983-8. 2010
    ....
  48. ncbi request reprint Milk--good for bones, good for reducing childhood obesity?
    Connie M Weaver
    Food and Nutrition Department, Purdue University, West Lafayette, IN 47907, USA
    J Am Diet Assoc 103:1598-9. 2003
  49. ncbi request reprint Comparative effect of soy protein, soy isoflavones, and 17beta-estradiol on bone metabolism in adult ovariectomized rats
    David J Cai
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907, USA
    J Bone Miner Res 20:828-39. 2005
    ..Results confirmed the bone-preserving effect of estrogen but did not support a bone-sparing role of soy isoflavones...
  50. ncbi request reprint Exercise and calcium supplementation: effects on calcium homeostasis in sportswomen
    Berdine R Martin
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 2059, USA
    Med Sci Sports Exerc 39:1481-6. 2007
    ..A second aim was to determine the effectiveness of calcium supplementation to offset any calcium loss...
  51. ncbi request reprint Daily supplementation with 25 μg cholecalciferol does not increase calcium absorption or skeletal retention in adolescent girls with low serum 25-hydroxyvitamin D
    Clara Y Park
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 2059, USA
    J Nutr 140:2139-44. 2010
    ..In pubertal girls with vitamin D status considered insufficient in adults, vitamin D supplementation of 25 μg/d for 4 wk did not improve fractional Ca absorption, net Ca absorption, or Ca retention...
  52. ncbi request reprint Comparison of 24 hour whole body versus patch tests for estimating body surface electrolyte losses
    Cristina Palacios
    Department of Foods adn Nutrition, Purdue University, West Lafayette, IN 47907 1264, USA
    Int J Sport Nutr Exerc Metab 13:479-88. 2003
    ..To compare dermal electrolyte loss between whole body and regional patch methods in women during 24-h...
  53. ncbi request reprint Absorption of calcium fumarate salts is equivalent to other calcium salts when measured in the rat model
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, 1264 Stone Hall, West Lafayette, Indiana 47907 1264, USA
    J Agric Food Chem 50:4974-5. 2002
    ..05). Thus, when measured in the rat model, calcium from calcium fumarate and calcium malate fumarate is absorbed equally well as compared to other salts, which are common calcium sources in many foods, beverages, and supplements...
  54. ncbi request reprint Food insecurity is associated with iron deficiency anemia in US adolescents
    Heather A Eicher-Miller
    Department of Foods and Nutrition and Statistics, Purdue University, West Lafayette, IN 47907 2059, USA
    Am J Clin Nutr 90:1358-71. 2009
    ..Food insecurity, a condition of low or very low food security, is associated with decreased nutrient intake and poor health, which can lead to nutrient deficiency in children, including iron deficiency and iron deficiency anemia...
  55. ncbi request reprint Calcium bioavailability and kinetics of calcium ascorbate and calcium acetate in rats
    Jianwei Cai
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907, USA
    Exp Biol Med (Maywood) 229:40-5. 2004
    ..The higher bioavailability of calcium ascorbate was due to a longer transit time in the small intestine compared with ASC...
  56. pmc Technologies and experimental approaches at the National Institutes of Health Botanical Research Centers
    Stephen Barnes
    Botanical Center for Age Related Disease, Purdue University University of Alabama at Birmingham, West Lafayette, IN, USA
    Am J Clin Nutr 87:476S-80S. 2008
    ..In summary, the skills needed to carry out botanical centers' research are extensive and may exceed those practiced by most NIH investigators...
  57. ncbi request reprint Acute versus chronic effects of whey proteins on calcium absorption in growing rats
    Yongdong Zhao
    Department of Foods and Nutrition, Purdue University, 700 W State Street, West Lafayette, IN 47907 2059, USA
    Exp Biol Med (Maywood) 230:536-42. 2005
    ..However, the initial enhancement of calcium absorption by whey protein was sufficient to increase BMC...
  58. ncbi request reprint Vitamin D, calcium homeostasis, and skeleton accretion in children
    Connie M Weaver
    Department of Foods and Nutrition, Purdue University, Lafayette, Indiana, USA
    J Bone Miner Res 22:V45-9. 2007
    ..Current cross-sectional studies in children suggest that vitamin D status is less important for bone accrual than for bone health in adults. Intervention studies are needed to identify responsive groups...
  59. ncbi request reprint The effect of soy protein and soy isoflavones on calcium metabolism in postmenopausal women: a randomized crossover study
    Lisa A Spence
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN, USA
    Am J Clin Nutr 81:916-22. 2005
    ..Evidence suggests that soy isoflavones act as estrogen agonists and have beneficial skeletal effects, but the effects on calcium metabolism in humans are not known...
  60. doi request reprint Acute and chronic effects of honey and its carbohydrate constituents on calcium absorption in rats
    Merlin W Ariefdjohan
    Department of Foods and Nutrition, Purdue University, 700 West State Street, West Lafayette, Indiana 47907 2059, USA
    J Agric Food Chem 56:2649-54. 2008
    ....
  61. ncbi request reprint Sodium retention in black and white female adolescents in response to salt intake
    Cristina Palacios
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907, USA
    J Clin Endocrinol Metab 89:1858-63. 2004
    ..In summary, black girls showed greater Na(+) retention compared with white girls. The difference in Na(+) handling may contribute to underlying racial differences in susceptibility to hypertension...
  62. ncbi request reprint The effect of exercise on water balance in premenopausal physically active women
    Eileen M Weinheimer
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
    J Am Diet Assoc 108:1662-7. 2008
    ..This controlled feeding study examined the effects of exercise on daily water intake (particularly ad libitum water intake), water output, whole-body water balance, and hydration status in physically active, premenopausal women...
  63. ncbi request reprint Effects of hindlimb unloading and bisphosphonates on the serum proteome of rats
    Yongdong Zhao
    Department of Foods and Nutrition, Purdue University, 700 W State St, West Lafayette, IN 47907 2059, USA
    Bone 41:646-58. 2007
    ..e. drug related), and 17 common to HU and HUA (e.g. potential mental stress or muscle loss markers). Spots were identified by LC-MS/MS after in-gel trypsin digestion and were found to relate to a variety of physiological functions...
  64. pmc Comparison of self-reported, measured, metabolizable energy intake with total energy expenditure in overweight teens
    Rajni Singh
    Department of Foods and Nutrition and Statistics, Purdue University, West Lafayette, IN 47907 2059, USA
    Am J Clin Nutr 89:1744-50. 2009
    ..The accuracy of dietary energy assessment tools is critical to understanding the role of diet in the increasing rate of obesity...
  65. ncbi request reprint Effect of calcium carbonate particle size on calcium absorption and retention in adolescent girls
    Ann E Elble
    Purdue University, Department of Foods and Nutrition, 700 W State St, West Lafayette, IN 47907 2059, USA
    J Am Coll Nutr 30:171-7. 2011
    ..The aim of the study was to compare (1) large versus small particle size CaCO(3) supplements and (2) small particle size CaCO(3) supplement versus placebo on calcium absorption and retention in adolescent girls...
  66. pmc Obesity augments calcium-induced increases in skeletal calcium retention in adolescents
    Kathleen M Hill
    Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47906, USA
    J Clin Endocrinol Metab 96:2171-7. 2011
    ..Overweight adolescents have low bone mineral content for weight and are at increased risk for fractures...
  67. ncbi request reprint Whole versus the piecemeal approach to evaluating soy
    Susan Reinwald
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 2059, USA
    J Nutr 140:2335S-2343S. 2010
    ..It explores the rationale for focusing research on whole soy in an attempt to understand it better rather than trying to replicate the health benefits by targeting various soy components, which has been plagued by inconsistent results...
  68. pmc Soy components vs. whole soy: are we betting our bones on a long shot?
    Susan Reinwald
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 2059, USA
    J Nutr 140:2312S-2317S. 2010
    ..This forces one to ask whether whole soy might provide a superior effect on bone...
  69. ncbi request reprint Calcium and exercise affect the growing skeleton
    Jo M Welch
    School of Health and Human Performance, Dalhousie University, Halifax, Nova Scotia, Canada
    Nutr Rev 63:361-73. 2005
    ....
  70. ncbi request reprint Newer perspectives on calcium nutrition and bone quality
    Robert P Heaney
    Creighton University Medical Center, 601 N 30th St, Suite 4841, Omaha, NE 68131, USA
    J Am Coll Nutr 24:574S-81S. 2005
    ..High calcium intakes in postmenopausal and older women reduce this homeostatic remodeling to approximately pre-menopausal values and improve bone strength immediately, well prior to any appreciable change in bone mass...
  71. ncbi request reprint MyPyramid food intake pattern modeling for the Dietary Guidelines Advisory Committee
    Patricia Britten
    USDA Center for Nutrition Policy and Promotion, Alexandria, VA 22302, USA
    J Nutr Educ Behav 38:S143-52. 2006
    ..Modeling analyses can help researchers explore the overall effect of specific dietary recommendations on intake patterns...
  72. ncbi request reprint Calcium and vitamin D
    Robert P Heaney
    Department of Medicine, Creighton University Medical Center, Omaha, NE 68131, USA
    Endocrinol Metab Clin North Am 32:181-94, vii-viii. 2003
    ..Prudent nutritional support for osteoporosis prevention and treatment consists of 30 to 40 mmol Ca/d together with sufficient vitamin D to maintain serum 25(OH)D levels above 80 nmol/L (i.e., approximately 25 microg vitamin D/d)...
  73. ncbi request reprint Calcium utilization in young women: new insights from modeling
    Meryl E Wastney
    Metabolic Modeling Services Ltd, Hamilton 2030, Dalesford, New Zealand
    Adv Exp Med Biol 537:193-205. 2003
  74. ncbi request reprint Calcium intake, body fat, and bones--a complex relation
    Connie M Weaver
    Am J Clin Nutr 86:527. 2007
  75. ncbi request reprint Race and diet interactions in the acquisition, maintenance, and loss of bone
    MARCELLA D WALKER
    Division of Endocrinology, Metabolic Bone Disease Unit, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Nutr 138:1256S-60S. 2008
    ..Predictors of aBMD have been reported for African American and American white adults and predictors of aBMD in Chinese American women have recently been studied. Much remains to be studied regarding interactions between race and diet...
  76. ncbi request reprint Are current calcium recommendations for adolescents higher than needed to achieve optimal peak bone mass? The controversy
    Stephanie A Atkinson
    Department of Pediatrics, McMaster University, Hamilton, Canada
    J Nutr 138:1182-6. 2008
  77. ncbi request reprint Back to basics: have milk with meals
    Connie M Weaver
    J Am Diet Assoc 106:1756-8. 2006
  78. ncbi request reprint Sorting out bioactivity in flavonoid mixtures
    Mary Ann Lila
    Department of Natural Resources and Environmental Sciences, University of Illinois, Urbana, IL 61801 7715, USA
    J Nutr 135:1231-5. 2005
    ..The biolabeled materials are now being investigated to determine tissue localization, structures of bioactive components, and the interactions between flavonoid components that contribute to bioactive potential...
  79. doi request reprint Black and white female adolescents lose vitamin D metabolites into urine
    Myrtle Thierry-Palmer
    Department of Biochemistry, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310 1495, USA
    Am J Med Sci 335:278-83. 2008
    ..We tested the hypothesis that urinary vitamin D metabolite content and 25-hydroxyvitamin D (25-OHD) binding activity of black female adolescents would be greater than that of white female adolescents...

Research Grants26

  1. Calcium, Dairy, and Body Fat in Adolescents
    Connie Weaver; Fiscal Year: 2006
    ..This study will evaluate calcium/dairy as a modulator of energy balance, important to the management of body fat in children. ..
  2. CALCIUM METABOLISM IN ADOLESCENT BOYS
    Connie Weaver; Fiscal Year: 2002
    ..Optimizing calcium accretion during this rapid period of growth should maximize peak bone mass within the genetic potential and reduce risk of osteoporosis later. ..
  3. Calcium Metabolism in Mexican American Adolescents
    Connie M Weaver; Fiscal Year: 2010
    ....
  4. 24,25-DIHYDROXYVITAMIN D: MARKER OF SALT SENSITIVITY
    Connie Weaver; Fiscal Year: 2001
    ..Furthermore, they should provide an explanation for the paradox that blacks can build higher bone density, have a lower rate of bone turnover, and excrete less urinary calcium on the same sodium loads compared to whites. ..
  5. CALCIUM METABOLISM IN ADOLESCENT BOYS
    Connie Weaver; Fiscal Year: 2001
    ..Optimizing calcium accretion during this rapid period of growth should maximize peak bone mass within the genetic potential and reduce risk of osteoporosis later. ..
  6. SODIUM INTAKE AND CALCIUM RETENTION IN ADOLESCENT GIRLS
    Connie Weaver; Fiscal Year: 2001
    ..Furthermore, they should provide an explanation for the paradox that blacks can build higher bone density, have a lower rate of bone turnover, and excrete less urinary calcium on the same sodium loads compared to whites. ..
  7. CALCIUM METABOLISM in ASIAN AMERICAN ADOLESCENTS
    Connie Weaver; Fiscal Year: 2004
    ..Optimizing calcium retention during periods of rapid growth is a key nutritional strategy to build peak bone mass and reduce lifelong risk of osteoporosis. ..
  8. Calcium, Dairy, and Body Fat in Adolescents
    Connie Weaver; Fiscal Year: 2004
    ..This study will evaluate calcium/dairy as a modulator of energy balance, important to the management of body fat in children. ..
  9. Calcium, Dairy, and Body Fat in Adolescents
    Connie Weaver; Fiscal Year: 2005
    ..This study will evaluate calcium/dairy as a modulator of energy balance, important to the management of body fat in children. ..
  10. CALCIUM METABOLISM IN ASIAN GIRLS AND POSTMENOPAUSAL WOMEN
    Connie Weaver; Fiscal Year: 2005
    ..Optimizing calcium retention during periods of rapid growth is a key nutritional strategy to build peak bone mass and reduce lifelong risk of osteoporosis. ..
  11. CALCIUM METABOLISM IN ASIAN GIRLS AND POSTMENOPAUSAL WOMEN
    Connie Weaver; Fiscal Year: 2006
    ..Optimizing calcium retention during periods of rapid growth is a key nutritional strategy to build peak bone mass and reduce lifelong risk of osteoporosis. ..
  12. Calcium Metabolism in Mexican American Adolescents
    Connie Weaver; Fiscal Year: 2009
    ....
  13. CALCIUM METABOLISM IN ADOLESCENT BOYS
    Connie Weaver; Fiscal Year: 2000
    ..Optimizing calcium accretion during this rapid period of growth should maximize peak bone mass within the genetic potential and reduce risk of osteoporosis later. ..
  14. SODIUM INTAKE AND CALCIUM RETENTION IN ADOLESCENT GIRLS
    Connie Weaver; Fiscal Year: 2000
    ..Furthermore, they should provide an explanation for the paradox that blacks can build higher bone density, have a lower rate of bone turnover, and excrete less urinary calcium on the same sodium loads compared to whites. ..
  15. SODIUM INTAKE AND CALCIUM RETENTION IN ADOLESCENT GIRLS
    Connie Weaver; Fiscal Year: 1999
    ..Furthermore, they should provide an explanation for the paradox that blacks can build higher bone density, have a lower rate of bone turnover, and excrete less urinary calcium on the same sodium loads compared to whites. ..
  16. CALCIUM METABOLISM IN ADOLESCENT GIRLS AND YOUNG WOMEN
    Connie Weaver; Fiscal Year: 1990
    ..Correlations with hormone levels and biochemical markers of bone turnover will also be made...
  17. CALCIUM METABOLISM IN ADOLESCENT GIRLS
    Connie Weaver; Fiscal Year: 1993
    ..Correlations between calcium retention/kinetics and hormone levels, biochemical markers of bone turnover and bone mass, and total body calcium will be determined...
  18. CALCIUM METABOLISM IN ADOLESCENT GIRLS AND YOUNG WOMEN
    Connie Weaver; Fiscal Year: 1991
    ..Correlations with hormone levels and biochemical markers of bone turnover will also be made...
  19. CALCIUM METABOLISM IN ADOLESCENT GIRLS AND YOUNG WOMEN
    Connie Weaver; Fiscal Year: 1992
    ..Correlations with hormone levels and biochemical markers of bone turnover will also be made...
  20. CALCIUM METABOLISM IN ADOLESCENT GIRLS
    Connie Weaver; Fiscal Year: 1999
    ..The relationship of calcium balance and biomarkers to menstruation and ovulation will also be studied. ..