David J Waters

Summary

Affiliation: Purdue University
Country: USA

Publications

  1. ncbi request reprint Aging research 2011: exploring the pet dog paradigm
    David J Waters
    Center for Exceptional Longevity Studies, Gerald P Murphy Cancer Foundation, 3000 Kent Avenue, Suite E2 100, West Lafayette, IN 47906, USA
    ILAR J 52:97-105. 2011
  2. pmc Prostatic response to supranutritional selenium supplementation: comparison of the target tissue potency of selenomethionine vs. selenium-yeast on markers of prostatic homeostasis
    David J Waters
    Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN 47907, USA
    Nutrients 4:1650-63. 2012
  3. doi request reprint The art of casting nets: fishing for the prize of personalized cancer prevention
    David J Waters
    The Center on Aging and the Life Course, Purdue University, and Gerald P Murphy Cancer Foundation West Lafayette, IN 47906, USA
    Nutr Cancer 60:1-6. 2008
  4. pmc Exploring mechanisms of sex differences in longevity: lifetime ovary exposure and exceptional longevity in dogs
    David J Waters
    Center for Exceptional Longevity Studies, Gerald P Murphy Cancer Foundation, 3000 Kent Avenue, West Lafayette, IN 47906, USA
    Aging Cell 8:752-5. 2009
  5. doi request reprint Probing the perils of dichotomous binning: how categorizing female dogs as spayed or intact can misinform our assumptions about the lifelong health consequences of ovariohysterectomy
    D J Waters
    Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, Indiana, USA
    Theriogenology 76:1496-500. 2011
  6. ncbi request reprint Noninvasive prediction of prostatic DNA damage by oxidative stress challenge of peripheral blood lymphocytes
    David J Waters
    Gerald P Murphy Cancer Foundation, 3000 Kent Avenue, Suite E2 100, West Lafayette, IN 47906, USA
    Cancer Epidemiol Biomarkers Prev 16:1906-10. 2007
  7. ncbi request reprint Prostate cancer risk and DNA damage: translational significance of selenium supplementation in a canine model
    David J Waters
    Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN 47907, USA
    Carcinogenesis 26:1256-62. 2005
  8. ncbi request reprint Effects of dietary selenium supplementation on DNA damage and apoptosis in canine prostate
    David J Waters
    Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN 47907, USA
    J Natl Cancer Inst 95:237-41. 2003
  9. ncbi request reprint Exceptional longevity in pet dogs is accompanied by cancer resistance and delayed onset of major diseases
    Dawn M Cooley
    Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, Indiana, USA
    J Gerontol A Biol Sci Med Sci 58:B1078-84. 2003
  10. pmc Defining the Optimal Selenium Dose for Prostate Cancer Risk Reduction: Insights from the U-Shaped Relationship between Selenium Status, DNA Damage, and Apoptosis
    Emily C Chiang
    Gerald P Murphy Cancer Foundation, West Lafayette, IN Interdepartmental Nutrition Program and The Center on Aging and the Life Course, Purdue University, West Lafayette, IN
    Dose Response 8:285-300. 2009

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Aging research 2011: exploring the pet dog paradigm
    David J Waters
    Center for Exceptional Longevity Studies, Gerald P Murphy Cancer Foundation, 3000 Kent Avenue, Suite E2 100, West Lafayette, IN 47906, USA
    ILAR J 52:97-105. 2011
    ..Yet the pet dog paradigm in aging research is nascent; tapping into the potential of this model will add to the existing strengths of conventional model systems...
  2. pmc Prostatic response to supranutritional selenium supplementation: comparison of the target tissue potency of selenomethionine vs. selenium-yeast on markers of prostatic homeostasis
    David J Waters
    Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN 47907, USA
    Nutrients 4:1650-63. 2012
    ....
  3. doi request reprint The art of casting nets: fishing for the prize of personalized cancer prevention
    David J Waters
    The Center on Aging and the Life Course, Purdue University, and Gerald P Murphy Cancer Foundation West Lafayette, IN 47906, USA
    Nutr Cancer 60:1-6. 2008
    ..Every fisherman knows that where he casts his net determines his catch. Now, we ask: When it comes to solving the cancer problem, where should we be casting our nets?..
  4. pmc Exploring mechanisms of sex differences in longevity: lifetime ovary exposure and exceptional longevity in dogs
    David J Waters
    Center for Exceptional Longevity Studies, Gerald P Murphy Cancer Foundation, 3000 Kent Avenue, West Lafayette, IN 47906, USA
    Aging Cell 8:752-5. 2009
    ..This work introduces a conceptual framework for designing additional studies in pet dogs to define the ovary-sensitive biological processes that promote healthy human longevity...
  5. doi request reprint Probing the perils of dichotomous binning: how categorizing female dogs as spayed or intact can misinform our assumptions about the lifelong health consequences of ovariohysterectomy
    D J Waters
    Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, Indiana, USA
    Theriogenology 76:1496-500. 2011
    ....
  6. ncbi request reprint Noninvasive prediction of prostatic DNA damage by oxidative stress challenge of peripheral blood lymphocytes
    David J Waters
    Gerald P Murphy Cancer Foundation, 3000 Kent Avenue, Suite E2 100, West Lafayette, IN 47906, USA
    Cancer Epidemiol Biomarkers Prev 16:1906-10. 2007
    ..These findings lend support to the concept that oxidative stress contributes to genotoxic damage, and that oxidative stress challenge may stratify men for prostate cancer risk...
  7. ncbi request reprint Prostate cancer risk and DNA damage: translational significance of selenium supplementation in a canine model
    David J Waters
    Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN 47907, USA
    Carcinogenesis 26:1256-62. 2005
    ....
  8. ncbi request reprint Effects of dietary selenium supplementation on DNA damage and apoptosis in canine prostate
    David J Waters
    Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN 47907, USA
    J Natl Cancer Inst 95:237-41. 2003
    ..7 (interquartile range = 0.2-2.8) for the control dogs ( P =.04, Mann-Whitney U test). These data suggest that dietary selenium supplementation decreases DNA damage and increases epithelial cell apoptosis within the aging canine prostate...
  9. ncbi request reprint Exceptional longevity in pet dogs is accompanied by cancer resistance and delayed onset of major diseases
    Dawn M Cooley
    Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, Indiana, USA
    J Gerontol A Biol Sci Med Sci 58:B1078-84. 2003
    ..0001). The reduction in cancer mortality in oldest-old pet dogs mimics that seen in human centenarians and provides strong rationale for using this animal model to study comparative mechanisms of cancer resistance in the extreme aged...
  10. pmc Defining the Optimal Selenium Dose for Prostate Cancer Risk Reduction: Insights from the U-Shaped Relationship between Selenium Status, DNA Damage, and Apoptosis
    Emily C Chiang
    Gerald P Murphy Cancer Foundation, West Lafayette, IN Interdepartmental Nutrition Program and The Center on Aging and the Life Course, Purdue University, West Lafayette, IN
    Dose Response 8:285-300. 2009
    ..8 ppm in toenails can achieve cancer risk reduction through daily supplementation...
  11. ncbi request reprint Making sense of sex and supplements: differences in the anticarcinogenic effects of selenium in men and women
    David J Waters
    Gerald P Murphy Cancer Foundation, 1291 Cumberland Ave, West Lafayette, IN 47906, USA
    Mutat Res 551:91-107. 2004
    ..Ultimately, achieving the ambitious goal of cancer prevention may require sex- and gender-specific approaches...
  12. ncbi request reprint Influence of host factors on survival in dogs with malignant mammary gland tumors
    Jeffrey C Philibert
    Department of Veterinary Clinical Sciences, Purdue University School of Veterinary Medicine, West Lafayette, IN, USA
    J Vet Intern Med 17:102-6. 2003
    ..Further study of other prognostic factors is needed to determine which tumors are adequately addressed with local therapy only and which dogs may require adjuvant treatment with chemotherapy...
  13. ncbi request reprint Cancer clues from pet dogs
    David J Waters
    Purdue University, USA
    Sci Am 295:94-101. 2006
  14. ncbi request reprint Folate-conjugated liposomes preferentially target macrophages associated with ovarian carcinoma
    Mary Jo Turk
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907, USA
    Cancer Lett 213:165-72. 2004
    ..These results demonstrate that, in addition to their cancer cell-targeting properties, folate-liposomes may be useful for targeting drugs to tumor-associated macrophages in vivo...
  15. ncbi request reprint Reevaluation of predictive factors for complete recovery in dogs with nonambulatory tetraparesis secondary to cervical disk herniation
    Robert B Hillman
    Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, 625 Harrison Street, West Lafayette, Indiana 47907 2026, USA
    J Am Anim Hosp Assoc 45:155-63. 2009
    ..Reliable preoperative predictors of complete recovery are needed to advance current diagnostic and treatment protocols to improve overall prognosis...
  16. ncbi request reprint Cyclooxygenase inhibitors in urinary bladder cancer: in vitro and in vivo effects
    Sulma I Mohammed
    Department of Veterinary Clinical Sciences, Purdue University, 625 Harrison Street, West Lafayette, IN 47907 2026, USA
    Mol Cancer Ther 5:329-36. 2006
    ..Athymic mice bearing TCC xenografts provide a useful in vivo system for COX inhibitor studies. Results of this study provide justification for further evaluation of COX inhibitors as antitumor agents against TCC...
  17. pmc Supplemental dietary racemic equol has modest benefits to bone but has mild uterotropic activity in ovariectomized rats
    Leecole L Legette
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
    J Nutr 139:1908-13. 2009
    ..Dietary equol had no stimulatory effect on mammary gland epithelium. We conclude that in OVX rats, a dietary equol dose that had modest effect on bone also exerts mild uterotropic effects...
  18. ncbi request reprint Endogenous gonadal hormone exposure and bone sarcoma risk
    Dawn M Cooley
    Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, Indiana 47907, USA
    Cancer Epidemiol Biomarkers Prev 11:1434-40. 2002
    ....
  19. ncbi request reprint Preparation of 66Ga- and 68Ga-labeled Ga(III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals
    Carla J Mathias
    Department of Industrial and Physical Pharmacy, Purdue University, West, Lafayette, IN, USA
    Nucl Med Biol 30:725-31. 2003
    ..The autoradiographic images of 1 mm tumor sections demonstrate the gross heterogeneity of the KB cell tumor xenograft, as well as subtle disparity in the regional accumulation of the two radiotracers...
  20. ncbi request reprint Nuclear imaging of Met-expressing human and canine cancer xenografts with radiolabeled monoclonal antibodies (MetSeek)
    Rick V Hay
    Van Andel Research Institute, Grand Rapids, Michigan 49503, USA
    Clin Cancer Res 11:7064s-7069s. 2005
    ..In this study, we compared two antibodies, Met5 and Met3, for nuclear imaging of human and canine Met-expressing tumor xenografts in nude mice...
  21. doi request reprint Group consensus reports from the Consensus Conference on Focal Treatment of Prostatic Carcinoma, Celebration, Florida, February 24, 2006
    David G Bostwick
    Bostwick Laboratories, Richmond, Virginia 23060, USA
    Urology 70:42-4. 2007
  22. ncbi request reprint RNA interference reveals that ligand-independent met activity is required for tumor cell signaling and survival
    Nariyoshi Shinomiya
    Laboratory of Molecular Oncology, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA
    Cancer Res 64:7962-70. 2004
    ..Thus, Met small-interfering RNA adenoviruses are reliable tools for studying Met function and raise the possibility of their application for cancer therapy...
  23. ncbi request reprint Human prostate cancer risk factors
    David G Bostwick
    Bostwick Laboratories, Richmond, Virginia 23294, USA
    Cancer 101:2371-490. 2004
    ..An understanding of the risk factors for prostate cancer has practical importance for public health research and policy, genetic and nutritional education and chemoprevention, and prevention strategies...
  24. ncbi request reprint Preoperative prediction of multifocal prostate cancer and application of focal therapy: review 2007
    Isabelle Meiers
    Bostwick Laboratories, Glen Allen, Virginia 23060, USA
    Urology 70:3-8. 2007
    ..This article reviews the importance of multifocal prostate cancer and the application of focal treatment...