Research Topics
| D TeegardenSummaryAffiliation: Purdue University Country: USA Publications
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Publications
Effect of 1-year dairy product intervention on fat mass in young women: 6-month follow-upMarianne S Eagan
Department of Foods and Nutrition, Purdue University, 1264 Stone Hall, 700 West State Street, West Lafayette, IN 47907, USA
Obesity (Silver Spring) 14:2242-8. 2006..DISCUSSION: Dietary calcium intake over 18 months predicted a negative change in body fat mass. Thus, increased dietary calcium intakes through dairy products may prevent fat mass accumulation in young, healthy, normal-weight women...
Dietary calcium, protein, and phosphorus are related to bone mineral density and content in young womenD Teegarden
Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907 1264, USA
Am J Clin Nutr 68:749-54. 1998..Dietary factors have been implicated in modifying bone health, although the results remain controversial, particularly in young women...
Previous milk consumption is associated with greater bone density in young womenD Teegarden
Department of Foods and Nutrition and Health, Purdue University, West Lafayette, IN 47907, USA
Am J Clin Nutr 69:1014-7. 1999..Dietary calcium and milk intakes at specific ages may influence bone mineral measures at specific sites during development of peak bone mass...
Characterization of 25-hydroxyvitamin D binding protein from intestinal cellsD Teegarden
Department of Foods and Nutrition, Purdue University, West Lafayette, Indiana 47907, USA
Biochem Biophys Res Commun 275:845-9. 2000..In summary, cDBP bound 25OHD with greater affinity than either 1,25(OH)(2)D or 24,25 dihydroxyvitamin D, the cytosolic binding activity was down-regulated by 1,25(OH)(2)D and cBDP is distinct from the nuclear VDR...
Dairy product components and weight regulation: symposium overviewDorothy Teegarden
Purdue University, West Lafayette, IN, USA
J Nutr 133:243S-244S. 2003
Calcium intake and reduction in weight or fat massDorothy Teegarden
Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
J Nutr 133:249S-251S. 2003..The implications of these results are that calcium may play a substantial contributing role in reducing the incidence of obesity and prevalence of the insulin resistance syndrome...
Parathyroid hormone is associated with decreased fat mass in young healthy womenC W Gunther
Interdepartmental Nutrition Program, Purdue University, Department of Foods and Nutrition, West Lafayette, IN 47907, USA
Int J Obes (Lond) 30:94-9. 2006..CONCLUSION: Fasting serum PTH was associated with increased fat mass, in both cross-sectional and prospective analysis. Thus, serum PTH may play a role in the regulation of body fat mass in young women...
Peak spine and femoral neck bone mass in young womenY-C Lin
Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907-1264, USA
Bone 32:546-53. 2003..We conclude that age of attaining peak bone mass at the hip is younger than at the spine, and BMC and BSA at the spine continue to increase through the early thirties in females...
Calcium and dairy product modulation of lipid utilization and energy expenditureDorothy Teegarden
Interdepartmental Nutrition Program, Purdue University, West Lafayette, Indiana, USA
Obesity (Silver Spring) 16:1566-72. 2008..The purpose of this study was to investigate the impact of dietary calcium or dairy product intake on total energy expenditure (TEE), fat oxidation, and thermic effect of a meal (TEM) during a weight loss trial...
Impact of exercise on bone health and contraindication of oral contraceptive use in young womenC M Weaver
Department of Foods and Nutrition, Purdue University, 1264 Stone Hall, West Lafayette, IN 47907 1264, USA
Med Sci Sports Exerc 33:873-80. 2001..The effect of quantified resistance and high impact exercise training on bone mass as modified by age and oral contraceptive (OCont) use in young women was studied...
Dairy products do not lead to alterations in body weight or fat mass in young women in a 1-y interventionCarolyn W Gunther
Departments of Foods and Nutrition, Purdue University, West Lafayette, IN, USA
Am J Clin Nutr 81:751-6. 2005..5 +/- 2.5, 0.3 +/- 2.7, and 0.5 +/- 3.5 kg, respectively; P = 0.26). CONCLUSION: Increased intake of dairy products does not alter body weight or fat mass in young, healthy women over 1 y...
Can the controversial relationship between dietary calcium and body weight be mechanistically explained by alterations in appetite and food intake?Dorothy Teegarden
Department of Foods and Nutrition, Purdue University, 700 West State Street, West Lafayette, Indiana, USA
Nutr Rev 66:601-5. 2008..Thus, this new evidence does not support the hypothesis that high calcium or dairy intake reduces appetite or food intake...
Fat oxidation and its relation to serum parathyroid hormone in young women enrolled in a 1-y dairy calcium interventionCarolyn W Gunther
Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907-1264, USA
Am J Clin Nutr 82:1228-34. 2005..CONCLUSIONS: The results suggest that a chronic diet high in dairy calcium increases whole-body fat oxidation from a meal, and increases in fasting serum PTH relate to decreases in postprandial whole-body fat oxidation...
Vitamin D: emerging new roles in insulin sensitivityDorothy Teegarden
Interdepartmental Nutrition Program, Purdue University, West Lafayette, IN 47907, USA
Nutr Res Rev 22:82-92. 2009..Thus, substantial evidence supports a relationship between vitamin D status and insulin sensitivity; however, the underlying mechanisms require further exploration...
The influence of dairy product consumption on body compositionDorothy Teegarden
Interdepartmental Nutrition Program, Purdue University, West Lafayette, IN 47907, USA
J Nutr 135:2749-52. 2005..If dairy products or their components have an effect on altering fat mass, it is likely to be a small change that may have a substantial effect on the incidence of obesity over time...
Dietary calcium intake protects women consuming oral contraceptives from spine and hip bone lossDorothy Teegarden
Interdepartmental Nutrition Program, 700 West State Street, Stone Hall 1264, Purdue University, West Lafayette, Indiana 47907, USA
J Clin Endocrinol Metab 90:5127-33. 2005..It is estimated that 80% of all women have used oral contraceptives (OCP), but OCP use may prevent attainment of maximal peak bone mass in young women and thus increase the risk of osteoporosis later in life...
1,25-dihydroxyvitamin D inhibits vitamin E succinate-induced apoptosis in C3H10T1/2 cells but not Harvey ras-transfected cellsLynn Stedman
Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
Nutr Cancer 45:93-100. 2003..In conclusion, VES exerts its effect intact and 1,25(OH)2D3 preferentially protects C3H10T1/2 cells, whereas ras-transformed cells were not protected from VES-mediated apoptosis...
1α, 25-Dihydroxyvitamin D regulates hypoxia-inducible factor-1α in untransformed and Harvey-ras transfected breast epithelial cellsYan Jiang
Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47906, USA
Cancer Lett 298:159-66. 2010..These results support that 1,25(OH)(2)D regulates HIF-1α protein level via transcriptional regulation in MCF10A cells in contrast to through proteosomal degradation with the presence of H-ras oncogene in MCF10A cells...
Dietary intervention with vitamin D, calcium, and whey protein reduced fat mass and increased lean mass in ratsShamim M K Siddiqui
Interdepartmental Nutrition Program, Purdue University, West Lafayette, IN 47907, USA
Nutr Res 28:783-90. 2008....
Mechanisms of nuclear vitamin D receptor resistance in Harvey-ras-transfected cellsLaura M Taber
Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
J Nutr Biochem 20:629-37. 2009....
1alpha,25-Dihydroxyvitamin D hydroxylase in adipocytesJia Li
Interdepartmental Nutrition Program, Purdue University, West Lafayette, IN 47907, USA
J Steroid Biochem Mol Biol 112:122-6. 2008..Thus, the capacity for local production may play a role in regulating adipocyte growth and metabolism...
1alpha,25-dihydroxycholecalciferol increases the expression of vascular endothelial growth factor in C3H10T1/2 mouse embryo fibroblastsMarci J Levine
Interdepartmental Nutrition Program, Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
J Nutr 134:2244-50. 2004..These data contribute to understanding the role 1,25(OH)(2)D(3) plays in regulation of angiogenesis in normal compared with disease states...
The acute effects of dairy calcium intake on fat metabolism during exercise and endurance exercise performanceKimberly M White
Department of Health and Kinesiology, Purdue University, West Lafayette, Indiana, USA
Int J Sport Nutr Exerc Metab 16:565-79. 2006..Following this protocol, acute dairy calcium intake did not alter fat utilization or endurance performance in trained female runners...
Comparison of self-reported, measured, metabolizable energy intake with total energy expenditure in overweight teensRajni Singh
Department of Foods and Nutrition and Statistics, Purdue University, West Lafayette, IN 47907 2059, USA
Am J Clin Nutr 89:1744-50. 2009..The accuracy of dietary energy assessment tools is critical to understanding the role of diet in the increasing rate of obesity...
Parathyroid hormone suppresses insulin signaling in adipocytesEugene Chang
Interdepartmental Nutrition Program, Purdue University, West Lafayette, IN 47907, USA
Mol Cell Endocrinol 307:77-82. 2009..Thus, PTH treatment of differentiated 3T3-L1 adipocytes suppresses insulin-stimulated glucose uptake and insulin signaling via cAMP pathway, potentially through the phosphorylation of IRS-1 at serine 307...
1,25-dihydroxycholecalciferol inhibits apoptosis in C3H10T1/2 murine fibroblast cells through activation of nuclear factor kappaBLynn S Adams
Department of Foods and Nutrition, Purdue University, West, Lafayette, IN 47907, USA
J Nutr 134:2948-52. 2004..In summary, NFkappaB transcriptional activation was essential to 1,25(OH)(2)D(3) protection from VES-mediated apoptosis and 1,25(OH)(2)D(3) regulated NFkappaB activity through PI3K and PAK pathways...
Sphingosine-1-phosphate inhibition of apoptosis requires mitogen-activated protein kinase phosphatase-1 in mouse fibroblast C3H10T 1/2 cellsS Sianna Castillo
Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907-1264, USA
J Nutr 133:3343-9. 2003..Thus, both ERK activation and MKP-1, which down-regulates SAPK/JNK, are required for S1P-mediated inhibition of apoptosis...
Activation of rapid signaling pathways does not contribute to 1 alpha,25-dihydroxyvitamin D3-induced growth inhibition of mouse prostate epithelial progenitor cellsJia Li
Interdepartmental Nutrition Program, Purdue University, 700 W State Street, West Lafayette, Indiana 47907, USA
J Cell Biochem 107:1031-6. 2009..In conclusion, 1,25(OH)(2)D did not mediate rapid activation of ERK1/2 or PKC alpha in MPEC3 and therefore the growth inhibitory effect of 1,25(OH)(2)D is independent of rapid activation of these signaling pathways in this cell type...
Hispanic and Asian pubertal girls have higher android/gynoid fat ratio than whitesRachel Novotny
Department of Human Nutrition, Food and Animal Sciences, University of Hawaii at Manoa, 1955 East West Road, AgSci Building, Room 216, Honolulu, HI 96822, USA
Obesity (Silver Spring) 15:1565-70. 2007..To examine differences in body size, composition, and distribution of body fat among Hispanic, white, and Asian adolescents...
