Hamid Mirzaei

Summary

Affiliation: Purdue University
Country: USA

Publications

  1. ncbi Creation of allotypic active sites during oxidative stress
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    J Proteome Res 5:2159-68. 2006
  2. ncbi Identification and quantification of protein carbonylation using light and heavy isotope labeled Girard's P reagent
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA
    J Chromatogr A 1134:122-33. 2006
  3. ncbi Protein-RNA cross-linking in the ribosomes of yeast under oxidative stress
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    J Proteome Res 5:3249-59. 2006
  4. ncbi Protein:protein aggregation induced by protein oxidation
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, IN 47907 2084, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 873:8-14. 2008
  5. ncbi Identification of yeast oxidized proteins: chromatographic top-down approach for identification of carbonylated, fragmented and cross-linked proteins in yeast
    Hamid Mirzaei
    Department of Chemistry, Purdue University West Lafayette, IN 47907, USA
    J Chromatogr A 1141:22-31. 2007
  6. ncbi Identification of oxidized proteins in rat plasma using avidin chromatography and tandem mass spectrometry
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, IN 47907 2084, USA
    Proteomics 8:1516-27. 2008
  7. ncbi Destabilization of DJ-1 by familial substitution and oxidative modifications: implications for Parkinson's disease
    John D Hulleman
    Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, USA
    Biochemistry 46:5776-89. 2007
  8. ncbi Affinity chromatographic selection of carbonylated proteins followed by identification of oxidation sites using tandem mass spectrometry
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    Anal Chem 77:2386-92. 2005
  9. ncbi Enhancing electrospray ionization efficiency of peptides by derivatization
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    Anal Chem 78:4175-83. 2006
  10. ncbi Enrichment of carbonylated peptides using Girard P reagent and strong cation exchange chromatography
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    Anal Chem 78:770-8. 2006

Collaborators

Detail Information

Publications17

  1. ncbi Creation of allotypic active sites during oxidative stress
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    J Proteome Res 5:2159-68. 2006
    ..This suggests that, when regulation or disease progression is mediated by protein oxidation, specific new "allotypic active sites" are being created in proteins that trigger the process...
  2. ncbi Identification and quantification of protein carbonylation using light and heavy isotope labeled Girard's P reagent
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA
    J Chromatogr A 1134:122-33. 2006
    ....
  3. ncbi Protein-RNA cross-linking in the ribosomes of yeast under oxidative stress
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    J Proteome Res 5:3249-59. 2006
    ..Aggregation of proteins with ribosomal RNA has not been previously reported. The probable impact of this phenomenon cells is to diminish the protein synthesis capacity...
  4. ncbi Protein:protein aggregation induced by protein oxidation
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, IN 47907 2084, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 873:8-14. 2008
    ..These proteins are part of the proteome known as the aggresome. The protein content of the aggresome may provide vital information for mechanistic studies targeting disease and aging...
  5. ncbi Identification of yeast oxidized proteins: chromatographic top-down approach for identification of carbonylated, fragmented and cross-linked proteins in yeast
    Hamid Mirzaei
    Department of Chemistry, Purdue University West Lafayette, IN 47907, USA
    J Chromatogr A 1141:22-31. 2007
    ..Finally, peptides from two or more proteins occurred together in more than one reversed phase fraction with 2% of the proteins identified. This data was interpreted to mean that this was the result of protein cross-linking...
  6. ncbi Identification of oxidized proteins in rat plasma using avidin chromatography and tandem mass spectrometry
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, IN 47907 2084, USA
    Proteomics 8:1516-27. 2008
    ..The most frequently encountered proteins in the samples were keratins. Brain and liver were among the organs contributing the most oxidized proteins to plasma followed by heart and kidney...
  7. ncbi Destabilization of DJ-1 by familial substitution and oxidative modifications: implications for Parkinson's disease
    John D Hulleman
    Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, USA
    Biochemistry 46:5776-89. 2007
    ..Our findings provide a structural basis for DJ-1 dysfunction in familial and sporadic PD, and they suggest that dimer stabilization is a reasonable therapeutic strategy to treat both forms of this disorder...
  8. ncbi Affinity chromatographic selection of carbonylated proteins followed by identification of oxidation sites using tandem mass spectrometry
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    Anal Chem 77:2386-92. 2005
    ..The significance of this affinity method is that it allows the isolation of oxidized proteins from the rest of the proteome and facilitates their identification. In some cases, it is even possible to identify the site of oxidation...
  9. ncbi Enhancing electrospray ionization efficiency of peptides by derivatization
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    Anal Chem 78:4175-83. 2006
    ..Poor ionization efficiency of native peptides was found to be due more to their inherent structural properties than the matrix in which ionization occurs...
  10. ncbi Enrichment of carbonylated peptides using Girard P reagent and strong cation exchange chromatography
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    Anal Chem 78:770-8. 2006
    ..Efficiency of the method was further demonstrated in the identification of oxidized proteins from yeast...
  11. ncbi Structure specific chromatographic selection in targeted proteomics
    Hamid Mirzaei
    Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907-2084, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 817:23-34. 2005
    ..Protein interaction with small molecules as well as other proteins also has been studied using chromatographic selection methods...
  12. ncbi Neural network prediction of peptide separation in strong anion exchange chromatography
    Cheolhwan Oh
    Bindley Bioscience Center, West Lafayette, IN 47907, USA
    Bioinformatics 23:114-8. 2007
    ..New informatics tools are needed to model the experimental analysis method that will allow scientists to predict peptide separation and assist with required data mining steps, such as protein identification...
  13. ncbi Glutathione-S-transferase P1 is a critical regulator of Cdk5 kinase activity
    Kai Hui Sun
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    J Neurochem 118:902-14. 2011
    ..Given the critical role of oxidative stress in AD pathogenesis, an increase in GSTP1 level may be an alternative way to modulate Cdk5 signaling, eliminate oxidative stress, and prevent neurodegeneration...
  14. ncbi Identification of rotenone-induced modifications in alpha-synuclein using affinity pull-down and tandem mass spectrometry
    Hamid Mirzaei
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    Anal Chem 78:2422-31. 2006
    ..Our affinity pull-down/mass spectrometry method is a useful tool to examine how specific modifications of alpha-synuclein contribute to neurologic disorders such as Parkinson's disease...
  15. ncbi Evaluating immobilized metal affinity chromatography for the selection of histidine-containing peptides in comparative proteomics
    Diya Ren
    Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
    J Proteome Res 2:321-9. 2003
    ..Although the selection of N-terminally derivatized peptides is biased toward peptides that contain more than one histidine, it is not yet possible to predict selectivity...
  16. ncbi Comparative evaluation of current peptide production platforms used in absolute quantification in proteomics
    Hamid Mirzaei
    Institute for Systems Biology, Seattle, Washington 98103, USA
    Mol Cell Proteomics 7:813-23. 2008
    ..Overall neither the chemical synthesis nor the recombinant genetic approach proved to be superior as a method for the production of reference peptides for absolute quantification...
  17. ncbi A database of mass spectrometric assays for the yeast proteome
    Paola Picotti
    Nat Methods 5:913-4. 2008